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(16)
Ashida H
(1)
Chun KH
(1)
Hah SS
(1)
Hong SH
(1)
Jung YK
(1)
Kang W
(1)
Kim HC
(1)
Kim NY
(1)
Kim TY
(1)
Le LTM
(1)
Le le TM
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Lee HM
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Lim B
(1)
Lim YC
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Yang JK
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Yokota A
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Homo / hetero assembly
(1)
homo
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protein structure
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tetramer
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1.5 - 2
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2010 - 2015
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Proc Natl Acad Sci U S A
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Homo sapiens
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Molecule name
(4)
APAF1-interacting protein
(1)
MTRu-1-P dehydratase
(1)
Methylthioribulose-1-phosphate dehydratase
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hAPIP
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APIP
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CGI-29
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ZN : ZINC ION
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Function and Biology
EC number / name
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4.2.1.109 : Methylthioribulose 1-phosphate dehydratase
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identical protein binding
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lyase activity
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metal ion binding
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methylthioribulose 1-phosphate dehydratase activity
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protein binding
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Biological process
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L-methionine salvage from methylthioadenosine
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amino acid biosynthetic process
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apoptotic process
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negative regulation of apoptotic process
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protein homotetramerization
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pyroptotic inflammatory response
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regulation of ERK1 and ERK2 cascade
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cytoplasm
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L-fuculose-1-phosphate Aldolase
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PF00596 : Aldolase_II
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Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme
Kang W, Hong SH, Lee HM, Kim NY, Lim YC, Le LTM, Lim B, Kim HC, Kim TY, Ashida H, Yokota A, Hah SS, Chun KH, Jung YK, Yang JK
Proc Natl Acad Sci U S A
(2014)
[PMID: 24367089 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Assembly name:
Methylthioribulose-1-phosphate dehydratase
(Preferred)
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PDBe complex ID:
PDB-CPX-188524 (Preferred)
search this ID
PDBe-KB:
Q96GX9
Entries 1 to 1 of 1