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X-ray diffraction
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(53)
Bode W
(2)
Debela M
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Goettig P
(2)
Huber R
(2)
Magdolen V
(2)
Schechter NM
(2)
Arron JR
(1)
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Zhang J
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J Mol Biol
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Acta Crystallogr F Struct Biol Commun
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(4)
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KLK-L2
(4)
Kallikrein-5
(4)
Kallikrein-like protein 2
(4)
Stratum corneum tryptic enzyme
(4)
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Protein
(4)
Gene names
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KLK5
(4)
SCTE
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UNQ570/PRO1132
(4)
Interacting Molecules
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LEUPEPTIN
(2)
anti-KLK5 Fab Heavy Chain
(1)
anti-KLK5 Fab Light Chain
(1)
Interacting ligands
(5)
NAG : 2-acetamido-2-deoxy-beta-D-glucopyranose
(3)
J08 : 4-[(5-phenyl-1~{H}-imidazol-2-yl)methylamino]-2-(pyridin-3-ylmethoxy)benzenecarboximidamide
(1)
NA : SODIUM ION
(1)
SO4 : SULFATE ION
(1)
ZN : ZINC ION
(1)
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serine-type endopeptidase activity
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proteolysis
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Thrombin, subunit H
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PF00089 : Trypsin
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(4)
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Representative Structures
Representative Structures
Entries
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Entries 1 to 4 of 4
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Crystal Structure of Human Kallikrein 5 in complex with Leupeptin
Debela M, Bode W, Goettig P
J Mol Biol
(2007)
[PMID: 17881000 ]
Source organisms: Homo sapiens , Streptomyces roseus
Assembly composition: protein/protein complex
Carbohydrate polymer components:
Molecule 1 -
NAG(2)
Assembly name:
Kallikrein-5 and peptide
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-163179 (Preferred)
search this ID

Crystal Structure of Human Kallikrein 5 in complex with GSK144
Thorpe JH
Acta Crystallogr F Struct Biol Commun
(2019)
[PMID: 31045568 ]
Source organism: Homo sapiens
Assembly composition: protein only structure
Carbohydrate polymer components:
Molecule 1 -
NAG(2)
Assembly name:
Kallikrein-5
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-195179 (Preferred)
search this ID

Crystal Structure of Human Kallikrein 5 in complex with Leupeptin and Zinc
Debela M, Bode W, Goettig P
J Mol Biol
(2007)
[PMID: 17881000 ]
Source organisms: Homo sapiens , Streptomyces roseus
Assembly composition: protein/protein complex
Carbohydrate polymer components:
Molecule 1 -
NAG(2)
Assembly name:
Kallikrein-5 and peptide
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-163180 (Preferred)
search this ID

Structure of Human KLK5 bound to anti-KLK5 Fab
Yin J, Sudhamsu J
Sci Transl Med
(2022)
[PMID: 36516271 ]
Source organisms: synthetic construct , Homo sapiens
Assembly composition: protein/protein complex
Bound ligands:
SO4
Assembly name:
Kallikrein-5 and IG-heavy chain and IG-light kappa chain
(Preferred)
search this complex
PDBe complex ID:
PDB-CPX-280355 (Preferred)
search this ID

Entries 1 to 4 of 4