Uniprot accession / id : Q9Z0W1  OR   Uniprot accession / id : P08138
 
Filter by :
Entry Information
Entry status  (1)
REL
(7)
 
Experimental methods  (2)
Solution NMR
(6)
X-ray diffraction
(1)
 
Authors  (34)
Ibanez CF
(6)
Lin Z
(6)
Gao JF
(3)
Goh ET
(3)
Ibáñez CF
(3)
Kelly C
(3)
Lim KB
(3)
Tann JY
(3)
Li Z
(2)
Ramanujan A
(2)
Ahn BY
(1)
Berger B
(1)
Cao P
(1)
Dang NH
(1)
Dong Y
(1)
Dymock B
(1)
Goh ETH
(1)
Gong Y
(1)
Gui W
(1)
Gui WJ
(1)
Ibanez C
(1)
Jiang T
(1)
Kisiswa L
(1)
Lopes-Rodrigues V
(1)
Ma Y
(1)
Salim S
(1)
Senger DL
(1)
Sim EW
(1)
Tian X
(1)
Yu HJ
(1)
Yuan W
(1)
Zhang N
(1)
Zhang W
(1)
Zhang WT
(1)
 
Homo / hetero assembly  (2)
hetero
(5)
homo
(2)
 
Assembly composition  (2)
protein/protein complex
(5)
protein structure
(2)
 
Assembly polymer count  (1)
dimer
(7)
 
Resolution distribution
2.5 - 3
(1)
 
Release year distribution
2005 - 2010
(1)
2010 - 2015
(3)
2015 - 2020
(4)
2020 - 2025
(2)
 
Journal  (5)
Elife
(3)
Acta Crystallogr D Biol Crystallogr
(1)
Cell Chem Biol
(1)
EMBO Rep
(1)
J Biol Chem
(1)
 
Macromolecules
Organism superkingdom  (1)
Eukaryota
(6)
 
Organism name  (2)
Homo sapiens
(6)
synthetic construct
(1)
 
Molecule name  (8)
Gp80-LNGFR
(7)
Low affinity neurotrophin receptor p75NTR
(7)
Low-affinity nerve growth factor receptor
(7)
Low-affinity nerve growth factor receptor p75NGFR
(7)
Low-affinity nerve growth factor receptor p75NGR
(7)
NGF receptor
(7)
Tumor necrosis factor receptor superfamily member 16
(7)
p75 ICD
(7)
 
Molecule type  (1)
Protein
(7)
 
Gene names  (2)
NGFR
(7)
TNFRSF16
(7)
 
Interacting Molecules  (4)
Rho GDP-dissociation inhibitor 1
(2)
Calmodulin-1
(1)
Receptor-interacting serine/threonine-protein kinase 2
(1)
Tumor necrosis factor receptor type 1-associated DEATH domain protein
(1)
 
Interacting ligands  (1)
9F6 : (2E)-1-(2-hydroxyphenyl)-3-(pyridin-3-yl)prop-2-en-1-one
(1)
 
Function and Biology
Biological process  (1)
signal transduction
(4)
 
Sequence and Structure classification
CATH class  (1)
Mainly Alpha
(3)
 
CATH topology  (1)
Death Domain, Fas
(3)
 
Pfam accession / name  (2)
PF00531 : Death
(4)
PF18422 : TNFR_16_TM
(1)
 
Experimental Information
Diffraction protocol  (1)
Single wavelength
(1)
 
Diffraction radiation source type  (1)
Rotating anode
(1)
 
Diffraction source  (1)
RIGAKU
(1)
 
Diffraction detector type  (1)
Image plate
(1)
 
Refinement software  (1)
REFMAC
(1)
 
NMR
NMR software packages  (4)
Amber
(6)
CYANA
(6)
NMRPipe
(6)
NMRView
(6)
 
NMR Field Strength
700.0 - 800
(6)
800.0 - 900
(6)
 
Representative Structures
Representative Structures
100%
95%
90%
70%
50%
40%
30%
Entries 1 to 7 of 7
Entries 1 to 7 of 7
 Select all entries on this page
NMR structure of p75NTR transmembrane domain in complex with NSC49652
Lin Z, Ibanez C
Cell Chem Biol (2018) [PMID: 30293939  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Bound ligands: 9F6    9F6   
Assembly name: Tumor necrosis factor receptor superfamily member 16 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139929 (Preferred)   search this ID
PDBe-KB: P08138   
Solution NMR
Released: 13 Mar 2019
Model geometry
Fit model/data
Data not analysed
5zgg
5zgg
5zgg
NMR structure of p75NTR juxtamembrane domain in complex with RhoGDI N-terminal domain containing a phosphorylation-mimicking S34D mutation
Lin Z, Li Z
EMBO Rep (2024) [PMID: 38253689  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: Tumor necrosis factor receptor superfamily member 16 and Rho GDP-dissociation inhibitor 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139927 (Preferred)   search this ID
PDBe-KB: P08138    P52565   
Solution NMR
Released: 3 Apr 2024
Model geometry
Fit model/data
Data not deposited
8x8t
8x8t
8x8t
Solution structure of the complex between p75NTR-DD and TRADD-DD
Lin Z, Zhang N
J Biol Chem (2021) [PMID: 34175311  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: Tumor necrosis factor receptor superfamily member 16 and Tumor necrosis factor receptor type 1-associated DEATH domain protein (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139928 (Preferred)   search this ID
PDBe-KB: P08138    Q15628   
Solution NMR
Released: 25 Aug 2021
Model geometry
Fit model/data
Data not analysed
7csq
7csq
7csq
p75NTR DD:RIP2 CARD
Lin Z, Ibanez CF
Elife (2015) [PMID: 26646181  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: Receptor-interacting serine/threonine-protein kinase 2 and Tumor necrosis factor receptor superfamily member 16 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-128906 (Preferred)   search this ID
PDBe-KB: P08138    O43353   
Solution NMR
Released: 23 Dec 2015
Model geometry
Fit model/data
Data not analysed
2n83
2n83
2n83
DD homodimer
Lin Z, Ibanez CF
Elife (2015) [PMID: 26646181  ]
Source organism: Homo sapiens  
Assembly composition: protein only structure
Assembly name: Tumor necrosis factor receptor superfamily member 16 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139929 (Preferred)   search this ID
PDBe-KB: P08138   
Solution NMR
Released: 23 Dec 2015
Model geometry
Fit model/data
Data not analysed
2n97
2n97
2n97
Crystal Structure of calmodulin complexed with a peptide
Jiang T, Cao P, Gong Y, Yu HJ, Gui WJ, Zhang WT
Acta Crystallogr D Biol Crystallogr (2014) [PMID: 24914971  ]
Assembly composition: protein/protein complex
Bound ligands: CA    CA   
Assembly name: Calmodulin-1 and Tumor necrosis factor receptor superfamily member 16 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139926 (Preferred)   search this ID
PDBe-KB: P08138    P0DP23   
X-ray diffraction
2.6Å resolution
Released: 20 Oct 2009
Model geometry
Fit model/data
3ewv
3ewv
3ewv
p75NTR DD:RhoGDI
Lin Z, Ibanez CF
Elife (2015) [PMID: 26646181  ]
Source organism: Homo sapiens  
Assembly composition: protein/protein complex
Assembly name: Tumor necrosis factor receptor superfamily member 16 and Rho GDP-dissociation inhibitor 1 (Preferred)   search this complex
PDBe complex ID: PDB-CPX-139927 (Preferred)   search this ID
PDBe-KB: P08138    P52565   
Solution NMR
Released: 23 Dec 2015
Model geometry
Fit model/data
Data not analysed
2n80
2n80
2n80
Entries 1 to 7 of 7
Entries 1 to 7 of 7