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PDBsum entry 1vcd
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protein ligands Protein-protein interface(s) links
Hydrolase PDB id
1vcd

 

 

 

 

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Contents
Protein chains
126 a.a. *
Ligands
SO4 ×2
GOL ×2
Waters ×183
* Residue conservation analysis
PDB id:
1vcd
Name: Hydrolase
Title: Crystal structure of a t.Thermophilus hb8 ap6a hydrolase ndx1
Structure: Ndx1. Chain: a, b. Synonym: mutt/nudix family protein. Engineered: yes
Source: Thermus thermophilus. Organism_taxid: 300852. Strain: hb8. Gene: ndx1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Resolution:
1.70Å     R-factor:   0.214     R-free:   0.237
Authors: T.Iwai,N.Nakagawa,S.Kuramitsu,R.Masui,Riken Structural Genomics/proteomics Initiative (Rsgi)
Key ref: T.Iwai et al. Crystal structure of nudix protein ndx1 from thermus thermophilus hb8 in binary complex with diadenosine hexaphosphate. To be published, .
Date:
05-Mar-04     Release date:   26-Apr-05    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
Q75UV1  (NDX1_THETH) -  Diadenosine hexaphosphate hydrolase from Thermus thermophilus
Seq:
Struc: 		126 a.a.
126 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.6.1.61  - diadenosine hexaphosphate hydrolase (ATP-forming).
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction:
1. P1,P6-bis(5'-adenosyl) hexaphosphate + H2O = 2 ATP + 2 H+
2. P1,P5-bis(5'-adenosyl) pentaphosphate + H2O = ADP + ATP + 2 H+
3. P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = AMP + ATP + 2 H+
P(1),P(6)-bis(5'-adenosyl) hexaphosphate
 + H2O
 = 2 × ATP
 + 2 × H(+)
P(1),P(5)-bis(5'-adenosyl) pentaphosphate
 + H2O
 = ADP
 + ATP
 + 2 × H(+)
P(1),P(4)-bis(5'-adenosyl) tetraphosphate
 + H2O
 = AMP
 + ATP
 + 2 × H(+)
      Cofactor: Divalent cation
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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