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PDBsum entry 5odb

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protein ligands Protein-protein interface(s) links
Immune system PDB id
5odb

 

 

 

 

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Contents
Protein chains
217 a.a.
207 a.a.
Ligands
SO4
GOL
Waters ×448
PDB id:
5odb
Name: Immune system
Title: Crystal structure of the ra-associated mab d10 (chimeric fab fragment)
Structure: D10 fab fragment - heavy chain. Chain: a. Engineered: yes. Other_details: not modeled residues are not visible in the electron density map the fab fragment was prepared from a antibody chimera containing the variable domains of the human d10 mab and the constant domains of mouse igg2a heavy chain and ig-lambda light chain. D10 fab fragment - light chain. Chain: b.
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell_line: b cells. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_taxid: 9606
Resolution:
1.53Å     R-factor:   0.189     R-free:   0.214
Authors: D.Dobritzsch,C.Ge,R.Holmdahl,K.Amara,V.Malmstrom
Key ref: C.Ge et al. (2019). Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies. Arthritis Rheumatol, 71, 210-221. PubMed id: 30152126 DOI: 10.1002/art.40698
Date:
05-Jul-17     Release date:   04-Jul-18    
PROCHECK
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 Headers
 References

Protein chain
No UniProt id for this chain
Struc: 217 a.a.
Protein chain
No UniProt id for this chain
Struc: 207 a.a.
Key:    Secondary structure

 

 
DOI no: 10.1002/art.40698 Arthritis Rheumatol 71:210-221 (2019)
PubMed id: 30152126  
 
 
Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies.
C.Ge, B.Xu, B.Liang, E.Lönnblom, S.L.Lundström, R.A.Zubarev, B.Ayoglu, P.Nilsson, T.Skogh, A.Kastbom, V.Malmström, L.Klareskog, R.E.M.Toes, T.Rispens, D.Dobritzsch, R.Holmdahl.
 
  ABSTRACT  
 
No abstract given.

 

 

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