M-CSA Mechanism and Catalytic Site Atlas

Naphthalene 1,2-dioxygenase (M-CSA:130)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this chain

The residue id shown is the one in the PDB sequence. This may be different from the resid given by the author of the PDB file.

PDB sequences identical to 1ndo

In these PDB chains all the catalytic residues are conserved and have the same numbering as the reference.

1eg9(A, B), 1o7g(A, B), 1o7h(A, B), 1o7m(A, B), 1o7n(A, B), 1o7p(A, B), 1o7w(A, B), 1uuv(A, B), 1uuw(A, B), 2hmj(B), 2hmk(A, B), 2hml(B), 2hmm(A, B), 2hmn(B), 2hmo(A, B), 4hkv(A, B), 4hm0(A, B), 4hm1(A, B), 4hm2(A, B), 4hm3(A, B), 4hm4(A, B), 4hm5(A, B), 4hm6(A, B), 4hm7(A, B), 4hm8(A, B)

PDB sequences homologous to 1ndo

Reference PDB chains/ identical chains	Homologous PDB chains	His104A Asp205E His208E His213E Asp362E
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2gbw(C,A,E) 2gbx(A,E,C)	His103 Asp204 His207 His212 Asp360
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	3eqq(A) 3en1(A)	His119 Asp219 His222 His228 Asp376
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	5hl4(A) 3vcp(A) 3vca(A)	His109 Glu201 His204 His209 Asn357
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2xso(K,W,U,O,M,S,A,Q,G,C,I,E) 2xsh(A,G,E,C,I,K)	His123 Asp230 His233 His239 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	1uli(A,E,C) 1ulj(C,A,E)	His121 Asp221 His224 His230 Asp378
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	5xbp(G,A,D)	His102 Asp203 His206 His211 Asp360
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	4qup(A) 4quq(A) 4qur(A)	His132 Glu224 His227 His232 Asn380
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	3n0q(A)	His107 Glu199 His202 His207 Asn354
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	6y8j(A) 6y8s(A) 6y9d(J,K,H,D,B,A,G,F,L,C,I,E) 6zgp(J,K,H,D,B,A,G,F,L,C,I,E)	His129 Glu225 His228 His233 not aligned
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	6y9c(A)	His129 Glu225 His228 His233 not aligned
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	7c8z(G,A,E,C)	His133 Asp240 His243 His248 Asp389
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2yfi(A,G,E,C,I,K) 2yfj(A,G,E,C,I,K) 2yfl(A,G,E,C,I,K)	His123 Asp230 His233 His239 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	1wql(A)	His124 Asp231 His234 His240 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2ckf(A,E,C)	His103 Asp204 His207 His212 Asp360
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2xrx(K,W,O,M,S,A,Q,G,E,C,I,U) 2xr8(K,U,W,M,S,A,Q,G,E,C,I,O)	His123 Asp230 His233 His239 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	4hjl(A)	His104 Asp205 His208 His213 Asp362
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	His104 Asp205 His208 His213 Asp362
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	5aew(W,U,O,M,S,A,Q,G,E,C,I,K) 5aeu(G,A,E,C)	His123 Asp230 His233 His239 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2hml(A) 2hmn(A) 2hmj(A)	His104 Asp205 His208 His213 Asp362
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2b24(C,A,E) 2b1x(C,A,E)	His111 Asp213 His216 His221 Asp372
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2bmr(A) 2bmo(A) 2bmq(A)	His102 Asp203 His206 His211 Asp360
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	3gzx(A) 3gzy(A)	His123 Asp230 His233 His239 Asp386
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2gbw(C,A,E) 2gbx(A,E,C)	His103 Asp204 His207 His212 Asp360
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	3eqq(A) 3en1(A)	His119 Asp219 His222 His228 Asp376
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	5hl4(A) 3vcp(A) 3vca(A)	His109 Glu201 His204 His209 Asn357
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2xso(K,W,U,O,M,S,A,Q,G,C,I,E) 2xsh(A,G,E,C,I,K)	His123 Asp230 His233 His239 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	1uli(A,E,C) 1ulj(C,A,E)	His121 Asp221 His224 His230 Asp378
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	5xbp(G,A,D)	His102 Asp203 His206 His211 Asp360
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	4qup(A) 4quq(A) 4qur(A)	His132 Glu224 His227 His232 Asn380
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	3n0q(A)	His107 Glu199 His202 His207 Asn354
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	6y8j(A) 6y8s(A) 6y9d(J,K,H,D,B,A,G,F,L,C,I,E) 6zgp(J,K,H,D,B,A,G,F,L,C,I,E)	His129 Glu225 His228 His233 not aligned
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	6y9c(A)	His129 Glu225 His228 His233 not aligned
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	7c8z(G,A,E,C)	His133 Asp240 His243 His248 Asp389
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2yfi(A,G,E,C,I,K) 2yfj(A,G,E,C,I,K) 2yfl(A,G,E,C,I,K)	His123 Asp230 His233 His239 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	1wql(A)	His124 Asp231 His234 His240 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2ckf(A,E,C)	His103 Asp204 His207 His212 Asp360
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2xrx(K,W,O,M,S,A,Q,G,E,C,I,U) 2xr8(K,U,W,M,S,A,Q,G,E,C,I,O)	His123 Asp230 His233 His239 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	4hjl(A)	His104 Asp205 His208 His213 Asp362
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	His104 Asp205 His208 His213 Asp362
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	5aew(W,U,O,M,S,A,Q,G,E,C,I,K) 5aeu(G,A,E,C)	His123 Asp230 His233 His239 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2hml(A) 2hmn(A) 2hmj(A)	His104 Asp205 His208 His213 Asp362
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2b24(C,A,E) 2b1x(C,A,E)	His111 Asp213 His216 His221 Asp372
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2bmr(A) 2bmo(A) 2bmq(A)	His102 Asp203 His206 His211 Asp360
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	3gzx(A) 3gzy(A)	His123 Asp230 His233 His239 Asp386
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2gbw(C,A,E) 2gbx(A,E,C)	His103 Asp204 His207 His212 Asp360
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	3eqq(A) 3en1(A)	His119 Asp219 His222 His228 Asp376
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	5hl4(A) 3vcp(A) 3vca(A)	His109 Glu201 His204 His209 Asn357
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2xso(K,W,U,O,M,S,A,Q,G,C,I,E) 2xsh(A,G,E,C,I,K)	His123 Asp230 His233 His239 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	1uli(A,E,C) 1ulj(C,A,E)	His121 Asp221 His224 His230 Asp378
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	5xbp(G,A,D)	His102 Asp203 His206 His211 Asp360
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	4qup(A) 4quq(A) 4qur(A)	His132 Glu224 His227 His232 Asn380
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	3n0q(A)	His107 Glu199 His202 His207 Asn354
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	6y8j(A) 6y8s(A) 6y9d(J,K,H,D,B,A,G,F,L,C,I,E) 6zgp(J,K,H,D,B,A,G,F,L,C,I,E)	His129 Glu225 His228 His233 not aligned
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	6y9c(A)	His129 Glu225 His228 His233 not aligned
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	7c8z(G,A,E,C)	His133 Asp240 His243 His248 Asp389
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2yfi(A,G,E,C,I,K) 2yfj(A,G,E,C,I,K) 2yfl(A,G,E,C,I,K)	His123 Asp230 His233 His239 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	1wql(A)	His124 Asp231 His234 His240 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2ckf(A,E,C)	His103 Asp204 His207 His212 Asp360
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2xrx(K,W,O,M,S,A,Q,G,E,C,I,U) 2xr8(K,U,W,M,S,A,Q,G,E,C,I,O)	His123 Asp230 His233 His239 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	4hjl(A)	His104 Asp205 His208 His213 Asp362
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	His104 Asp205 His208 His213 Asp362
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	5aew(W,U,O,M,S,A,Q,G,E,C,I,K) 5aeu(G,A,E,C)	His123 Asp230 His233 His239 Asp388
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2hml(A) 2hmn(A) 2hmj(A)	His104 Asp205 His208 His213 Asp362
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2b24(C,A,E) 2b1x(C,A,E)	His111 Asp213 His216 His221 Asp372
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	2bmr(A) 2bmo(A) 2bmq(A)	His102 Asp203 His206 His211 Asp360
1ndo(C,A,E) 1o7h(A) 2hmm(A) 2hmk(A) 1uuv(A) 4hm0(A) 4hm5(A) 1o7n(A) 4hm3(A) 4hm2(A) 4hkv(A) 1o7p(A) 4hm4(A) 2hmo(A) 4hm6(A) 4hm8(A) 1o7m(A) 1o7w(A) 4hm7(A) 1eg9(A) 1uuw(A) 1o7g(A) 4hm1(A)	3gzx(A) 3gzy(A)	His123 Asp230 His233 His239 Asp386