Pyruvate kinase (M-CSA:326)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this sequence

Homologous SwissProt sequences of P11974

Reference Sequence Homologue Arg73 Lys270 Thr328 Arg120
P11974
FunTreePfam
P11974
FunTreePfam
Arg73 Lys270 Thr328 Arg120
P11974
FunTreePfam
P52489
FunTreePfam
Arg51 Lys242 Thr300 Arg93
P11974
FunTreePfam
P80885
FunTreePfam
Arg32 Lys220 Thr278 Arg73
P11974
FunTreePfam
P46614
FunTreePfam
Arg53 Lys244 Thr302 Arg95
P11974
FunTreePfam
P73534
FunTreePfam
Arg38 Lys227 Thr285 Arg79
P11974
FunTreePfam
Q759A9
FunTreePfam
Arg50 Lys241 Thr299 Arg92
P11974
FunTreePfam
Q46289
FunTreePfam
Arg32 Lys219 Thr277 Arg73
P11974
FunTreePfam
O08309
FunTreePfam
Arg32 Lys219 Thr277 Arg73
P11974
FunTreePfam
Q875M9
FunTreePfam
Arg50 Lys241 Thr299 Arg92
P11974
FunTreePfam
O65595
FunTreePfam
Arg37 Lys227 Thr285 Arg78
P11974
FunTreePfam
P11979
FunTreePfam
Arg73 Lys270 Thr328 Arg120
P11974
FunTreePfam
P53657
FunTreePfam
Arg116 Lys313 Thr371 Arg163
P11974
FunTreePfam
P52480
FunTreePfam
Arg73 Lys270 Thr328 Arg120
P11974
FunTreePfam
Q5NVN0
FunTreePfam
Arg73 Lys270 Thr328 Arg120
P11974
FunTreePfam
P77983
FunTreePfam
Arg32 Lys220 Thr278 Arg73
P11974
FunTreePfam
Q29536
FunTreePfam
Arg116 Lys313 Thr371 Arg163
P11974
FunTreePfam
Q07637
FunTreePfam
Arg54 Lys250 Thr308 Arg95
P11974
FunTreePfam
Q875Z9
FunTreePfam
Arg50 Lys241 Thr299 Arg92
P11974
FunTreePfam
P22360
FunTreePfam
Arg63 Lys254 Thr312 Arg105
P11974
FunTreePfam
Q4L739
FunTreePfam
Arg32 Lys220 Thr278 Arg73
P11974
FunTreePfam
Q6FIS9
FunTreePfam
Arg50 Lys241 Thr299 Arg92
P11974
FunTreePfam
Q40546
FunTreePfam
Arg121 Lys306 Thr364 Ile163
P11974
FunTreePfam
Q8FP04
FunTreePfam
Arg33 Lys218 Thr276 Arg74
P11974
FunTreePfam
Q6BS75
FunTreePfam
Arg53 Lys244 Thr302 Arg95
P11974
FunTreePfam
Q2FXM9
FunTreePfam
Arg32 Lys219 Thr277 Arg73
P11974
FunTreePfam
P12928
FunTreePfam
Arg116 Lys313 Thr371 Arg163
P11974
FunTreePfam
Q9FLW9
FunTreePfam
Arg140 Lys325 Thr383 Arg182
P11974
FunTreePfam
Q42954
FunTreePfam
Arg48 Lys238 Thr296 Arg89
P11974
FunTreePfam
Q93Z53
FunTreePfam
Arg129 Lys314 Thr372 Arg171
P11974
FunTreePfam
P0AD61
FunTreePfam
Arg32 Lys220 Thr278 Arg73
P11974
FunTreePfam
Q5HNK7
FunTreePfam
Arg32 Lys219 Thr277 Arg73
P11974
FunTreePfam
P22200
FunTreePfam
Arg50 Lys240 Thr298 Arg91
P11974
FunTreePfam
P30613
FunTreePfam
Arg116 Lys313 Thr371 Arg163
P11974
FunTreePfam
Q10208
FunTreePfam
Arg56 Lys247 Thr305 Arg98
P11974
FunTreePfam
P30614
FunTreePfam
Arg60 Lys251 Thr309 Arg102
P11974
FunTreePfam
Q49YC7
FunTreePfam
Arg32 Lys220 Thr278 Arg73
P11974
FunTreePfam
O62619
FunTreePfam
Arg76 Lys273 Thr331 Arg123
P11974
FunTreePfam
Q42806
FunTreePfam
Arg51 Lys241 Thr299 Arg92
P11974
FunTreePfam
P11980
FunTreePfam
Arg73 Lys270 Thr328 Arg120
P11974
FunTreePfam
Q46078
FunTreePfam
Arg33 Lys218 Thr276 Arg74
P11974
FunTreePfam
Q55863
FunTreePfam
Arg46 Lys233 Thr291 Arg87
P11974
FunTreePfam
P00548
FunTreePfam
Arg72 Lys269 Thr327 Arg119
P11974
FunTreePfam
Q7RVA8
FunTreePfam
Arg62 Lys253 Thr311 Arg104
P11974
FunTreePfam
Q6FV12
FunTreePfam
Arg50 Lys241 Thr299 Arg92
P11974
FunTreePfam
P0CE21
FunTreePfam
Arg33 Lys219 Thr277 Arg74
P11974
FunTreePfam
P14618
FunTreePfam
Arg73 Lys270 Thr328 Arg120
P11974
FunTreePfam
Q54RF5
FunTreePfam
Arg50 Lys240 Thr298 Arg91
P11974
FunTreePfam
O51323
FunTreePfam
Arg34 Lys214 Thr272 Arg71
P11974
FunTreePfam
P47458
FunTreePfam
Arg56 Lys249 Thr307 Arg97
P11974
FunTreePfam
Q9WY51
FunTreePfam
Arg32 Lys217 Thr275 Arg73
P11974
FunTreePfam
B8BJ39
FunTreePfam
Arg58 Lys256 Thr313 Gln99
P11974
FunTreePfam
Q2RAK2
FunTreePfam
Arg58 Lys256 Thr313 Gln99
P11974
FunTreePfam
Q89AI8
FunTreePfam
Arg36 Lys223 Thr284 Arg77
P11974
FunTreePfam
P21599
FunTreePfam
Arg36 Lys223 Thr284 Arg77
P11974
FunTreePfam
B8BM17
FunTreePfam
Arg58 Lys256 Thr313 Gln99
P11974
FunTreePfam
Q57572
FunTreePfam
Arg33 Lys201 Thr259 Arg68
P11974
FunTreePfam
P9WKE5
FunTreePfam
Arg33 Lys218 Thr276 Arg74
P11974
FunTreePfam
Q8ZYE0
FunTreePfam
Arg46 Lys230 Thr288 Arg87
P11974
FunTreePfam
Q40545
FunTreePfam
Arg144 Lys341 Ser399 His185
P11974
FunTreePfam
P32044
FunTreePfam
Arg31 Lys202 Thr260 Arg68
P11974
FunTreePfam
O05118
FunTreePfam
Arg35 Lys217 Thr275 Arg76
P11974
FunTreePfam
P57404
FunTreePfam
Arg36 Lys223 Thr284 Arg77
P11974
FunTreePfam
Q8ZNW0
FunTreePfam
Arg36 Lys223 Thr284 Arg77
P11974
FunTreePfam
P78031
FunTreePfam
Arg56 Lys249 Thr307 Arg97
P11974
FunTreePfam
Q2QXR8
FunTreePfam
Arg58 Lys256 Thr313 Gln99
P11974
FunTreePfam
Q9YEU2
FunTreePfam
Arg33 Lys212 Thr270 Arg74
P11974
FunTreePfam
Q9LIK0
FunTreePfam
Arg147 Lys344 Ser402 His188
P11974
FunTreePfam
Q9M3B6
FunTreePfam
Arg265 Lys583 Thr647 Arg306
P11974
FunTreePfam
P43924
FunTreePfam
Arg36 Lys223 Thr284 Arg77
P11974
FunTreePfam
Q8SQP0
FunTreePfam
Arg34 Lys212 Thr270 Arg75
P11974
FunTreePfam
P00549
FunTreePfam
Arg49 Lys240 Thr298 Arg91
P11974
FunTreePfam
P0AD62
FunTreePfam
Arg32 Lys220 Thr278 Arg73
P11974
FunTreePfam
P30615
FunTreePfam
Arg50 Lys239 Thr297 Arg91
P11974
FunTreePfam
Q02499
FunTreePfam
Arg33 Lys221 Thr279 Arg74
P11974
FunTreePfam
Q27686
FunTreePfam
Arg50 Lys239 Thr297 Arg91
P11974
FunTreePfam
Q6GG09
FunTreePfam
Arg32 Lys219 Thr277 Arg73
P11974
FunTreePfam
Q2YTE3
FunTreePfam
Arg32 Lys219 Thr277 Arg73
P11974
FunTreePfam
Q9Z984
FunTreePfam
Arg33 Lys219 Thr277 Arg74
P11974
FunTreePfam
P55964
FunTreePfam
not aligned Lys163 Thr221 Arg21
P11974
FunTreePfam
P34038
FunTreePfam
Arg32 Lys221 Thr279 Arg73
P11974
FunTreePfam
Q12669
FunTreePfam
Arg63 Lys254 Thr312 Arg105
P11974
FunTreePfam
Q7A0N4
FunTreePfam
Arg32 Lys219 Thr277 Arg73
P11974
FunTreePfam
O30853
FunTreePfam
not aligned not aligned Thr43 not aligned
P11974
FunTreePfam
Q8K9M3
FunTreePfam
Arg36 Lys223 Thr284 Arg77
P11974
FunTreePfam
Q9PK61
FunTreePfam
Arg33 Lys219 Thr277 Arg74
P11974
FunTreePfam
O94122
FunTreePfam
Arg63 Lys254 Thr312 Arg106
P11974
FunTreePfam
Q2FG40
FunTreePfam
Arg32 Lys219 Thr277 Arg73
P11974
FunTreePfam
Q99TG5
FunTreePfam
Arg32 Lys219 Thr277 Arg73
P11974
FunTreePfam
Q875S4
FunTreePfam
Arg50 Lys241 Thr299 Arg92
P11974
FunTreePfam
B0B7Q0
FunTreePfam
Arg33 Lys219 Thr277 Arg74
P11974
FunTreePfam
Q56301
FunTreePfam
Arg36 Lys221 Thr279 Arg77
P11974
FunTreePfam
P94939
FunTreePfam
Arg33 Lys218 Thr276 Arg74
P11974
FunTreePfam
Q43117
FunTreePfam
Arg134 Lys331 Ser389 His175
P11974
FunTreePfam
Q7A559
FunTreePfam
Arg32 Lys219 Thr277 Arg73
P11974
FunTreePfam
Q8Z6K2
FunTreePfam
Arg32 Lys220 Thr278 Arg73
P11974
FunTreePfam
P70789
FunTreePfam
Arg37 Lys220 Thr278 Arg78
P11974
FunTreePfam
P9WKE4
FunTreePfam
Arg33 Lys218 Thr276 Arg74
P11974
FunTreePfam
Q04668
FunTreePfam
Arg48 not aligned not aligned Arg89
P11974
FunTreePfam
P51182
FunTreePfam
Arg32 Lys220 Thr278 Arg73
P11974
FunTreePfam
O44006
FunTreePfam
Arg86 Lys275 Thr333 Arg128
P11974
FunTreePfam
P30616
FunTreePfam
Arg50 Lys239 Thr297 Arg91
P11974
FunTreePfam
Q92122
FunTreePfam
Arg69 Lys266 Thr324 Arg116
P11974
FunTreePfam
Q44473
FunTreePfam
Arg37 Lys220 Thr278 Arg78
P11974
FunTreePfam
P51181
FunTreePfam
Arg32 Lys220 Thr278 Arg73
P11974
FunTreePfam
P31865
FunTreePfam
Arg72 Lys263 Thr321 Arg114
P11974
FunTreePfam
Q27788
FunTreePfam
Arg53 Lys238 Thr296 Arg94
P11974
FunTreePfam
Q5HF76
FunTreePfam
Arg32 Lys219 Thr277 Arg73
P11974
FunTreePfam
Q8CS69
FunTreePfam
Arg32 Lys219 Thr277 Arg73
P11974
FunTreePfam
Q6G8M9
FunTreePfam
Arg32 Lys219 Thr277 Arg73