Nuclease P1 (M-CSA:395)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this chain

The residue id shown is the one in the PDB sequence. This may be different from the resid given by the author of the PDB file.

PDB sequences homologous to 1ak0

Reference PDB chains/ identical chains Homologous PDB chains His60A His6A Trp1A (N-term) Arg48A Asp45A His116A Asp120A His126A His149A Asp153A
1ak0(A)
PfamFunTree
5fbd(A)
PfamFunTree
5fbc(A)
PfamFunTree
5fbf(A)
PfamFunTree
5fbb(B,A)
PfamFunTree
5fb9(B,A)
PfamFunTree
5fba(A)
PfamFunTree
His60 His6 Trp1 Lys48 Asp45 His115 Asp119 His125 His148 Asp152
1ak0(A)
PfamFunTree
5fbg(B,A)
PfamFunTree
His60 His6 Trp1 Lys48 Asn45 His115 Asp119 His125 His148 Asp152
1ak0(A)
PfamFunTree
4cxo(A)
PfamFunTree
His58 His6 Trp1 Lys48 Asp45 His120 Asp124 His130 His154 Asp158
1ak0(A)
PfamFunTree
1ak0(A)
PfamFunTree
x x x x x x x x x x
1ak0(A)
PfamFunTree
4dj4(B,A)
PfamFunTree
4jdg(A)
PfamFunTree
His60 His6 Trp1 Arg48 Asp45 His122 Asp126 His132 His156 Asp160
1ak0(A)
PfamFunTree
3sng(A)
PfamFunTree
His60 His6 Trp1 Arg48 Asp45 His122 Asp126 His132 His156 Asp160
1ak0(A)
PfamFunTree
4cxp(A)
PfamFunTree
4cwm(B,A)
PfamFunTree
4cxv(B,A)
PfamFunTree
3w52(A)
PfamFunTree
His58 His6 Trp1 Lys48 Asp45 His120 Asp124 His130 His154 Asp158