Phosphohistidine phosphatase (M-CSA:952)

Proteins that are close homologues to the M-CSA reference protein and have the same catalytic residues (highlighted in green, below) probably share the same mechanism. Please also check if the homologue shares the same FunTree Structural Cluster and the same Pfam family, as another measure of similarity.

Legend:
Reference Residue Conserved Residue Non Conserved Residue Outside Alignment Reference Residue not in this chain

The residue id shown is the one in the PDB sequence. This may be different from the resid given by the author of the PDB file.

PDB sequences homologous to 2hw4

Reference PDB chains/ identical chains Homologous PDB chains Ala54(73)A (main-N) His53(72)A Ser94(113)A Ala96(115)A (main-N) Arg78(97)A Lys21(40)A
2hw4(A)
PfamFunTree		 4z0n(A)
PfamFunTree		 Ser76 Gln75 not aligned not aligned not aligned Thr37
2hw4(A)
PfamFunTree		 2wa0(A)
PfamFunTree		 Val54 Leu53 not aligned not aligned not aligned not aligned
2hw4(A)
PfamFunTree		 2iwp(B,A)
PfamFunTree
2iwo(B,A)
PfamFunTree		 not aligned not aligned not aligned not aligned not aligned Thr35
2hw4(A)
PfamFunTree		 2ozx(A)
PfamFunTree
2ozw(A)
PfamFunTree
2ai6(A)
PfamFunTree		 Ala54 His53 Ser94 Ala96 Arg78 Lys21
2hw4(A)
PfamFunTree		 3fe1(B,A,C)
PfamFunTree		 Thr65 Phe64 not aligned not aligned not aligned Ser36
2hw4(A)
PfamFunTree		 2w4m(A)
PfamFunTree		 Glu68 Ala67 not aligned not aligned not aligned Ile40
2hw4(A)
PfamFunTree		 4hly(B,A)
PfamFunTree
4hlx(B,D,A,C)
PfamFunTree		 Arg108 Thr107 not aligned not aligned Pro132 Arg55
2hw4(A)
PfamFunTree		 4dqx(B,D,A,C)
PfamFunTree		 Asp81 Val80 not aligned not aligned not aligned not aligned
2hw4(A)
PfamFunTree		 3fxt(E,F,B,G,D,C,A,H)
PfamFunTree		 Pro77 Ile76 not aligned not aligned not aligned Ser36
2hw4(A)
PfamFunTree		 4u19(B,A,C)
PfamFunTree		 His56 Tyr55 not aligned not aligned not aligned Thr37
2hw4(A)
PfamFunTree		 2p8u(B,A)
PfamFunTree		 Asp93 Tyr92 not aligned not aligned not aligned Pro35
2hw4(A)
PfamFunTree		 5x29(E,B,D,A,C)
PfamFunTree		 not aligned Leu81 not aligned not aligned not aligned not aligned
2hw4(A)
PfamFunTree		 2vo1(B,A)
PfamFunTree		 Gly113 Thr112 not aligned not aligned not aligned His55
2hw4(A)
PfamFunTree		 4u1a(B,A,C)
PfamFunTree		 His56 Tyr55 not aligned not aligned not aligned Thr37
2hw4(A)
PfamFunTree		 4eek(A)
PfamFunTree
4een(A)
PfamFunTree
4eel(A)
PfamFunTree		 Tyr69 Met68 not aligned not aligned not aligned Val40
2hw4(A)
PfamFunTree		 3kjd(B,A)
PfamFunTree
3kcz(B,A)
PfamFunTree
4tvj(B,A)
PfamFunTree
4pjv(B,A)
PfamFunTree		 Ala54 Lys53 Phe94 Thr96 Ile78 not aligned
2hw4(A)
PfamFunTree		 2fne(B,A,C)
PfamFunTree		 not aligned not aligned not aligned not aligned not aligned Asp36
2hw4(A)
PfamFunTree		 4mpg(B,A)
PfamFunTree
4mpf(B,A)
PfamFunTree		 Asn71 Ile70 not aligned not aligned not aligned Ser36
2hw4(A)
PfamFunTree		 2bwg(B,D,A,C)
PfamFunTree
2ble(A)
PfamFunTree		 Pro71 Ile70 not aligned not aligned not aligned Lys35
2hw4(A)
PfamFunTree		 3p0c(B,A)
PfamFunTree		 His60 Phe59 not aligned not aligned not aligned Thr37
2hw4(A)
PfamFunTree		 2xs6(A)
PfamFunTree		 Glu65 Pro64 not aligned not aligned not aligned Ser35
2hw4(A)
PfamFunTree		 4yqy(B,A)
PfamFunTree		 Asp85 Gly84 not aligned not aligned not aligned not aligned
2hw4(A)
PfamFunTree		 4lk5(B,A,C)
PfamFunTree		 Thr65 Ile64 Asp105 Gly107 Gly89 Phe46
2hw4(A)
PfamFunTree		 3n8e(B,A)
PfamFunTree		 Cys72 Val71 not aligned not aligned not aligned Phe39
2hw4(A)
PfamFunTree		 4az9(B,A)
PfamFunTree		 His65 Phe64 not aligned not aligned not aligned Thr42
2hw4(A)
PfamFunTree		 2hw4(A)
PfamFunTree		 x x x x x x
2hw4(A)
PfamFunTree		 2nmm(B,A,C)
PfamFunTree		 Ala64 His63 Ser104 Ala106 Arg88 Lys31
2hw4(A)
PfamFunTree		 2r4h(B,A,C)
PfamFunTree		 not aligned not aligned not aligned not aligned not aligned Lys35
2hw4(A)
PfamFunTree		 4mch(A)
PfamFunTree
4lnh(A)
PfamFunTree
4mci(A)
PfamFunTree		 Gly73 Asn72 not aligned not aligned not aligned Val40
2hw4(A)
PfamFunTree		 2jku(A)
PfamFunTree		 not aligned not aligned not aligned not aligned not aligned Val37
2hw4(A)
PfamFunTree		 4has(B,A)
PfamFunTree		 Ala69 Phe68 not aligned not aligned not aligned not aligned
2hw4(A)
PfamFunTree		 3iuc(A,C)
PfamFunTree		 Thr67 Phe66 not aligned not aligned not aligned Ser38
2hw4(A)
PfamFunTree		 4n18(A)
PfamFunTree		 Leu100 Ala99 not aligned not aligned not aligned Cys42
2hw4(A)
PfamFunTree		 4jbb(A)
PfamFunTree		 Ala76 Tyr75 not aligned not aligned not aligned not aligned
2hw4(A)
PfamFunTree		 5cqe(B,A)
PfamFunTree		 Glu68 Met67 not aligned not aligned not aligned Leu36
2hw4(A)
PfamFunTree		 3tcs(B,A)
PfamFunTree		 Ser98 Gly97 not aligned not aligned not aligned Arg40
2hw4(A)
PfamFunTree		 5bp9(A)
PfamFunTree		 Pro91 Met90 not aligned not aligned not aligned Thr40
2hw4(A)
PfamFunTree		 4jwt(A)
PfamFunTree		 Thr59 Ala58 not aligned not aligned not aligned Ser36
2hw4(A)
PfamFunTree		 2f6q(B,A,C)
PfamFunTree		 His56 Tyr55 not aligned not aligned not aligned Thr37
2hw4(A)
PfamFunTree		 4l8t(A)
PfamFunTree		 Leu69 Met68 not aligned not aligned not aligned Lys44
2hw4(A)
PfamFunTree		 4jyj(B,A)
PfamFunTree		 Ala61 Ser60 not aligned not aligned not aligned Ala36
2hw4(A)
PfamFunTree		 3ly5(B,A)
PfamFunTree		 Lys83 His82 not aligned not aligned not aligned Glu50
2hw4(A)
PfamFunTree		 4hnl(A)
PfamFunTree		 Pro106 Gly105 not aligned not aligned not aligned Ser55
2hw4(A)
PfamFunTree		 4u18(B,A,C)
PfamFunTree		 His56 Tyr55 not aligned not aligned not aligned Thr37
2hw4(A)
PfamFunTree		 4zzl(B,A)
PfamFunTree		 Gln74 Leu73 not aligned not aligned not aligned Gln37
2hw4(A)
PfamFunTree		 3ec8(A)
PfamFunTree		 Glu64 Arg63 not aligned not aligned not aligned Lys39
2hw4(A)
PfamFunTree		 6dxp(B,A,D,C)
PfamFunTree		 x x x x x x
2hw4(A)
PfamFunTree		 6j3p(B,A)
PfamFunTree		 x x x x x x
2hw4(A)
PfamFunTree		 6xi9(B,A)
PfamFunTree
6xig(B,A)
PfamFunTree		 x x x x x x