In this course, participants will learn the necessary theoretical background and basic tools of molecular target identification in pathogens and building of compound libraries for virtual screening. We also will introduce general concepts of molecular docking simulations.

Who is this course for?

This course is for biological researchers who want to learn more about the application of structural information in their work and how to use some of the key bioinformatics resources that are available.
 
Prerequisites
No previous experience in the field of structural bioinformatics is required, however a basic knowledge of protein structure would be of benefit.

Participants should be familiar with basic Linux operations - http://www.ee.surrey.ac.uk/Teaching/Unix/ - and have some experience of bioinformatics tools and databases.

Important: We strongly recommend participants bring their own laptop with Linux OS for the course.

Please also note: this course will be taught in Spanish, however the trainers are fluent in English and can offer language support where feasible.

A number of travel fellowships are available for this course - early-stage researchers and researchers from underrepresented groups are especially encouraged to apply for CABANA travel fellowships. You can apply for travel fellowships via the course application form.

What will I learn?

Learning outcomes

After this course you should be able to:

• Describe how protein structure and molecular docking information can be applied to studies
• Use the PDBe protein structure database
• Identify potential protein targets using Target Pathogens
• Build compound library using LigQ web server

Course content

During this course you will learn about: 

• Protein structure databases (PDBe)
• Introduction to protein structure interpretation and docking
• Protein target identification using Target Pathogens (http://target.sbg.qb.fcen.uba.ar/patho/)
• Homology modeling using Modeller
• Binding site identification using FPocket
• Compound library building using LigQ web server

Trainers

In order to be considered for a place on this course applicants must complete the online application form.

Incomplete applications will NOT be considered.

If you have any queries about the registration process please email Guilherme Oliveira and Piv Gopalasingam.

Please note that the registration fee of $1200 ARS covers:

• Lunch and refreshment breaks
• Course materials 
• Course dinner on Friday 8 November

There will be a maximum of 26 participants on this course and registration is dependent on selection after successful completion of the application process.