The Open Targets Platform is a comprehensive research tool that supports systematic identification and prioritisation of potential therapeutic drug targets.‌ By integrating publicly available datasets along with data generated by the Open Targets consortium, the Platform builds and scores target-disease associations. Users can also explore relevant annotation information about targets, diseases, phenotypes, and drugs, as well as their most relevant relationships.

This webinar will provide an overview of the GraphQL API that powers the Open Targets Platform. The API provides multiple endpoints that support language-agnostic queries for a single entity or target-disease association. Users can also browse the schema to see available API fields and run sample queries using the API playground.

During the webinar, participants will have access to interactive walkthroughs and API queries that can be run directly in their browser. There will also be sample Python and R scripts that they can run to test different endpoints.

Who is this course for?

This webinar is suitable for lab-based and computational research scientists, graduate students, and post-doctoral research fellows working in early stage drug discovery.

No advance preparation is necessary. However, participants are encouraged to watch the Open Targets Platform webinar to get familiar with the Platform data model and data sources, and the research questions and use cases supported by the Platform.

Outcomes

By the end of the webinar you will be able to:

• Recall the different GraphQL API endpoints and fields that are available
• Use the API schema and playground to run sample queries
• Create an API query string to use with your programming language of choice
• Explore other ways to access Open Targets data for more comprehensive and systematic queries

DOI: 10.6019/TOL.OpenTargetsGraphQL-w.2021.00001.1

This webinar took place on 15th September 2021. Please click the 'Watch video' button to view the recording.