In this talk we will show advancements on the usage of supercomputer-based modelling and simulation in advanced biomedical applications, including tools for creating virtual populations of Virtual Human Twins and “Twinoids”. In particular, we will showcase computational achievements on coupled multi-scale and multi-physics problems to create in-silico clinical trials to understand physiology and to improve old and create new and better therapies. Regarding the application problems, we will present contributions on blood circulatory system, cardiac hemodynamics, bioprosthetic heart valves implants and valve reparation surgical procedures, respiratory fluid mechanics from upper airways down to alveoli, inhalers and nebulizers, lung models, spinal intrathecal fluid mechanics, etc.

About the speaker

Mariano Vázquez is CTO/CSO of the company ELEM Biotech, which develops and commercialises supercomputer-based applications for the biomedical sector, and researcher of the Barcelona Supercomputing Center, from which ELEM spun off in 2018. He has a PhD from the Technical University of Catalunya (UPC) with postdocs in Dassault Aviation and in INRIA Sophia Antipolis in France.

Who is this course for?

This webinar is part of PerMedCoE webinar series and is open for researchers in the life sciences, biomedical scientists and anyone interested in immuno-oncology as well as in simulation of intercellular interactions.

The goal of PerMedCoE is to provide an efficient and sustainable entry point to the HPC/Exascale-upgraded methodology to translate omics analyses into actionable models of cellular functions of medical relevance.

Outcomes

By the end of this webinar, you will be able to:

• Describe biomedical modelling at organ and system level
• Describe the potential of the Virtual Human Twin for medical applications

This webinar took place on 09 March 2023. Please click the 'Watch video' button to view the recording