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What are the signature domains/folds – CATH
- The presence of any CATH domain in the protein secondary structure is indicated in the 1D layout of the protein chain
- The 2D topology diagram can be coloured by CATH domain by selecting the pull-down option at the bottom of the topology diagram
- Clicking on the CATH domain information in the 1D layout (circled in red in Figure 27) highlights the presence of the same domain in the 2D and 3D layout
![](https://www.ebi.ac.uk/training/online/courses/exploring-pdb-entry/wp-content/uploads/sites/112/2020/10/CATH.png)