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What are the signature domains/folds – Pfam

  • The Pfam annotation of a particular protein is mapped against the primary sequence of the protein present in the entry
  • The 2D topology diagram provides you with an option to highlight the Pfam domain(s) present in a protein chain by selecting ‘Pfam’ from the pull-down menu (Figure 26)
Figure 26 The Pfam domain present in chain C of PDB entry 4KGC is highlighted in its 1D, 2D and 3D layout.