Designing functional genomics experiments

Like all experiments, functional genomics experiments begin with a biological question (Figure 9). This can be hypothesis driven (e.g. infection with influenza triggers interferon signalling pathways) or discovery/curiosity driven (e.g. what is the effect of salt treatment on gene expression in Arabidopsis plants?).

Design elements for functional genomics studies
Figure 9 Design elements for functional genomics studies.

Red i iconThree important things to consider when designing a functional genomics experiment are:

  • scale and intent
  • data analysis
  • reproducibility

We will discuss these in more detail over the next few pages.