Designing functional genomics experiments
Like all experiments, functional genomics experiments begin with a biological question (Figure 9). This can be hypothesis driven (e.g. infection with influenza triggers interferon signalling pathways) or discovery/curiosity driven (e.g. what is the effect of salt treatment on gene expression in Arabidopsis plants?).
Three important things to consider when designing a functional genomics experiment are:
We will discuss these in more detail over the next few pages. |