Viewing GO annotations

You can also use QuickGO to search, browse and filter all GO annotations by going to ‘View GO annotations’ (Figure 7).

At the time of publication, there are currently in excess of one billion annotations in GOA. To help find the gene ontologies you are interested in, you can filter the annotations using the columns in the GO annotation table (Figure 8):

• Taxon – Filter for annotations just to human or mouse gene products
• Gene product ID – If you interested in annotations to a specific protein or a group of proteins and you have their accession IDs
• Gene product type – Filter for annotations to just proteins, protein complexes or RNAs. The largest portion of our annotations are to proteins.
• GO term – If you are interested in annotations to a particular term or a group of terms
• GO aspect – If you want to view annotations to only biological process, molecular function, or cellular component
• Evidence – Only see annotations you are interested in from manual curation efforts or automatic annotation
• Qualifier – Filter for annotations with a specific relationship between the gene product and GO term
• Reference – Whether you want to sort for annotations from papers or from a particular automatic annotation source
• With/From – Filter for annotations for gene products that interact with other proteins
• Assigned By – Filter for GO annotations from a specific database or group

For more information and detail on how to use QuickGO, please watch our webinar on QuickGO and GO annotation.