- Course overview
- Search within this course
- What is the IMPC?
- How is IMPC data generated?
- Translating to other species and learning about human disease
- The home page of the IMPC website
- Searching for a gene of interest
- Gene pages
- Chart pages
- Searching for phenotypes
- Phenotype pages
- Late Adult data
- Image data
- Data downloads
- Try it yourself
- Quiz: check your learning
- Summary
- Your feedback
- Get help and support on the IMPC
- References
All materials are free cultural works licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license, except where further licensing details are provided.
References
- Bowl MR, Simon MM, Ingham NJ, Greenaway S, Santos L, Cater H, Taylor S, Mason J, Kurbatova N, Pearson S, et al. 2017. A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction. Nature Communications 8:886.
- Rozman J, Rathkolb B, Oestereicher MA, Schütt C, Ravindranath AC, Leuchtenberger S, Sharma S, Kistler M, Willershäuser M, Brommage R, et al. 2018. Identification of genetic elements in metabolism by high-throughput mouse phenotyping. Nature Communications 9: 288.
- Meehan TF, Conte N, West DB, Jacobsen JO, Mason J, Warren J, Chen C-K, Tudose I, Relac M, Matthews P, et al. 2017. Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium. Nature Genetics 49: 1231-1238.
- Cacheiro P, Muñoz-Fuentes V, Murray SA, Dickinson ME, Bucan M, Nutter LMJ, Peterson KA, Haselimashhadi H, Flenniken AM, Morgan H, et al. 2020. Human and mouse essentiality screens as a resource for disease gene discovery. Nature Communications 11: 655.
- Karp NA, Mason J, Beaudet AL, Benjamini Y, Bower L, Braun RE, Brown SDM, Chesler EJ, Dickinson ME, Flenniken AM, et al. 2017. Prevalence of sexual dimorphism in mammalian phenotypic traits. Nature Communications 8: 15475.
- Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, et al. 2016. High-throughput discovery of novel developmental phenotypes. Nature 537: 508-514.
- Muñoz-Fuentes V, Cacheiro P, Meehan TF, Aguilar-Pimentel JA, Brown SDM, Flenniken AM, Flicek P, Galli A, Mashhadi HH, Hrabě de Angelis M, et al. 2018. The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation. Conservation Genetics 19: 995-1005.
- Muñoz-Fuentes V, Cacheiro P, Meehan TF, Aguilar-Pimentel JA, Beaudet AL, Brown SDM, Dickinson ME, Flenniken AM, Flicek P, Galli A, et al. 2019. Correction to: The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation. Conservation Genetics 20: 135-136.
- Robinson PN, Köhler S, Oellrich A, Sanger Mouse Genetics P, Wang K, Mungall CJ, Lewis SE, Washington N, Bauer S, Seelow D, et al. 2014. Improved exome prioritization of disease genes through cross-species phenotype comparison. Genome Research 24:340-348.