Online tutorial

PDBeFold

Searching for structural homologues of a protein

Time to complete:

0.5 hour


Written by:

Last reviewed:

March 2024


Creative Commons

All materials are free cultural works licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license, except where further licensing details are provided.


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PDBeFold can be used to identify structural homologues in the PDB. PDBe's Secondary Structure Matching service (SSM) allows you to interactively compare, align and superimpose protein structures in 3D. This course will show you how to use PDBeFold and what you can do with it.

Feedback and help

Who is this course for?

This courses is suitable for anyone interested in learning about PDBeFold, however undergraduate knowledge of a life science subject would be an advantage. You may wish to look at the PDBe quick tour and Biomacromolecular structures course as an introduction to this tutorial.

What will I achieve?

By the end of the course you will be able to:

  • Evaluate what PDBeFold is and what it can do
  • Launch PDBeFold and search for 3D structures that are similar to your protein of interest
  • Interpret structural similarity of your results based on Q-scores
  • View and analyse structures from your returned results

What resources do I need?

There are no specific resources required to complete this course.

DOI: 10.6019/TOL.PDBeF-t.2014.00001.1