0%

Sequence & Isoform

This section displays the selected representative (canonical) protein sequence and all the isoforms described in the entry (Figure 34). It also includes information about the sequences including length and molecular weight. Isoforms can be generated from the same gene by alternative promoter usage, alternative splicing, alternative initiation or ribosomal frameshifting (or sometimes by a combination of these events). Isoform information includes both manually reviewed sequences, which may have specific names, functional information and experimental evidence associated with them, and also computationally mapped potential isoforms which are unreviewed records likely to belong to the same gene.

Figure 34 Two isoforms of  Caenorhabditis elegans X-box-binding protein 1, UniProtKB entry G5EE07. G5EE07-1 is the selected canonical sequence.