0%

Sequence (& isoforms)

This section displays by default the selected representative (canonical) protein sequence and all the isoforms described in the entry (Figure 31). It also includes information pertinent to the sequence(s), including length and molecular weight. Isoforms can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Isoform information includes both manually reviewed sequences, which may have specific names, functional information and experimental evidence associated with them, and also automatic gene-centric isoform mappings from eukaryotic reference proteome sequences.

Figure 31 Two isoforms of  Caenorhabditis elegans X-box-binding protein 1, UniProtKB entry G5EE07. G5EE07-1 is the selected canonical sequence.