{"metadata":{"accession":"IPR011650","entry_id":null,"type":"domain","go_terms":null,"source_database":"interpro","member_databases":{"pfam":{"PF07687":"Peptidase dimerisation domain"}},"integrated":null,"hierarchy":{"accession":"IPR011650","name":"Peptidase M20, dimerisation domain","type":"Domain","children":[]},"name":{"name":"Peptidase M20, dimerisation domain","short":"Peptidase_M20_dimer"},"description":[{"text":"<p>This domain consists of 4 β-strands and two α-helices which make up the dimerisation surface of members of the MEROPS peptidase family M20 [[cite:PUB00015203]]. This family includes a range of zinc exopeptidases: carboxypeptidases, dipeptidases and specialised aminopeptidases [[cite:PUB00003579]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00015203":{"PMID":9083113,"ISBN":null,"volume":"5","issue":"3","year":1997,"title":"Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy.","URL":null,"raw_pages":"337-47","medline_journal":"Structure","ISO_journal":"Structure","authors":["Rowsell S","Pauptit RA","Tucker AD","Melton RG","Blow DM","Brick P."],"DOI_URL":"http://dx.doi.org/10.1016/S0969-2126(97)00191-3"},"PUB00003579":{"PMID":7674922,"ISBN":null,"volume":"248","issue":null,"year":1995,"title":"Evolutionary families of metallopeptidases.","URL":null,"raw_pages":"183-228","medline_journal":"Methods Enzymol","ISO_journal":"Meth. Enzymol.","authors":["Rawlings ND","Barrett AJ."],"DOI_URL":"http://dx.doi.org/10.1016/0076-6879(95)48015-3"}},"set_info":null,"overlaps_with":[{"accession":"IPR036264","name":"Bacterial exopeptidase dimerisation domain","type":"homologous_superfamily"}],"counters":{"subfamilies":0,"domain_architectures":689,"interactions":0,"matches":279629,"pathways":72,"proteins":279484,"proteomes":12020,"sets":0,"structural_models":{"alphafold":208910},"structures":70,"taxa":46354},"entry_annotations":{"alignment:seed":175,"alignment:full":76198},"cross_references":{"ec":{"displayName":"ENZYME","description":"ENZYME is a repository of information relative to the nomenclature of enzymes. It is primarily based on the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB) and it describes each type of characterized enzyme for which an EC (Enzyme Commission) number has been provided.","rank":19,"accessions":[{"accession":"3.4.11.-","url":"https://enzyme.expasy.org/EC/3.4.11.-"},{"accession":"3.4.11.4","url":"https://enzyme.expasy.org/EC/3.4.11.4"},{"accession":"3.4.13.-","url":"https://enzyme.expasy.org/EC/3.4.13.-"},{"accession":"3.4.13.18","url":"https://enzyme.expasy.org/EC/3.4.13.18"},{"accession":"3.4.13.20","url":"https://enzyme.expasy.org/EC/3.4.13.20"},{"accession":"3.4.13.23","url":"https://enzyme.expasy.org/EC/3.4.13.23"},{"accession":"3.4.13.4","url":"https://enzyme.expasy.org/EC/3.4.13.4"},{"accession":"3.4.17.-","url":"https://enzyme.expasy.org/EC/3.4.17.-"},{"accession":"3.4.17.11","url":"https://enzyme.expasy.org/EC/3.4.17.11"},{"accession":"3.4.17.4","url":"https://enzyme.expasy.org/EC/3.4.17.4"},{"accession":"3.5.1.-","url":"https://enzyme.expasy.org/EC/3.5.1.-"},{"accession":"3.5.1.114","url":"https://enzyme.expasy.org/EC/3.5.1.114"},{"accession":"3.5.1.127","url":"https://enzyme.expasy.org/EC/3.5.1.127"},{"accession":"3.5.1.130","url":"https://enzyme.expasy.org/EC/3.5.1.130"},{"accession":"3.5.1.132","url":"https://enzyme.expasy.org/EC/3.5.1.132"},{"accession":"3.5.1.133","url":"https://enzyme.expasy.org/EC/3.5.1.133"},{"accession":"3.5.1.134","url":"https://enzyme.expasy.org/EC/3.5.1.134"},{"accession":"3.5.1.14","url":"https://enzyme.expasy.org/EC/3.5.1.14"},{"accession":"3.5.1.16","url":"https://enzyme.expasy.org/EC/3.5.1.16"},{"accession":"3.5.1.18","url":"https://enzyme.expasy.org/EC/3.5.1.18"},{"accession":"3.5.1.32","url":"https://enzyme.expasy.org/EC/3.5.1.32"},{"accession":"3.5.1.47","url":"https://enzyme.expasy.org/EC/3.5.1.47"},{"accession":"3.5.1.87","url":"https://enzyme.expasy.org/EC/3.5.1.87"},{"accession":"3.5.3.9","url":"https://enzyme.expasy.org/EC/3.5.3.9"},{"accession":"3.5.99.8","url":"https://enzyme.expasy.org/EC/3.5.99.8"}]}},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}