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{
    "metadata": {
        "accession": "IPR013154",
        "entry_id": null,
        "type": "domain",
        "go_terms": null,
        "source_database": "interpro",
        "member_databases": {
            "pfam": {
                "PF08240": "Alcohol dehydrogenase GroES-like domain"
            }
        },
        "integrated": null,
        "hierarchy": {
            "accession": "IPR013154",
            "name": "Alcohol dehydrogenase-like, N-terminal",
            "type": "Domain",
            "children": []
        },
        "name": {
            "name": "Alcohol dehydrogenase-like, N-terminal",
            "short": "ADH-like_N"
        },
        "description": [
            {
                "text": "<p>This is the catalytic domain of alcohol dehydrogenases ([ec:1.1.1.1]). Many of them contain an inserted zinc binding domain. This domain has a GroES-like structure; a name derived from the superfamily of proteins with a GroES fold. Proteins with a GroES fold structure have a highly conserved hydrophobic core and a glycyl-aspartate dipeptide which is thought to maintain the fold [[cite:PUB00017153], [cite:PUB00015341]].</p>",
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        "wikipedia": null,
        "literature": {
            "PUB00015341": {
                "PMID": 8804825,
                "ISBN": null,
                "volume": "6",
                "issue": "3",
                "year": 1996,
                "title": "Structural classification of proteins: new superfamilies.",
                "URL": null,
                "raw_pages": "386-94",
                "medline_journal": "Curr Opin Struct Biol",
                "ISO_journal": "Curr. Opin. Struct. Biol.",
                "authors": [
                    "Murzin AG."
                ],
                "DOI_URL": "http://dx.doi.org/10.1016/S0959-440X(96)80059-5"
            },
            "PUB00017153": {
                "PMID": 10556240,
                "ISBN": null,
                "volume": "12",
                "issue": "10",
                "year": 1999,
                "title": "Conserved structural features and sequence patterns in the GroES fold family.",
                "URL": null,
                "raw_pages": "815-8",
                "medline_journal": "Protein Eng",
                "ISO_journal": "Protein Eng.",
                "authors": [
                    "Taneja B",
                    "Mande SC."
                ],
                "DOI_URL": "http://dx.doi.org/10.1093/protein/12.10.815"
            }
        },
        "set_info": null,
        "overlaps_with": [
            {
                "accession": "IPR011032",
                "name": "GroES-like superfamily",
                "type": "homologous_superfamily"
            }
        ],
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            "domain_architectures": 4899,
            "interactions": 0,
            "matches": 538531,
            "pathways": 564,
            "proteins": 537162,
            "proteomes": 11525,
            "sets": 0,
            "structural_models": {
                "alphafold": 381194
            },
            "structures": 409,
            "taxa": 46155
        },
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            "alignment:full": 171194
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}