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{
    "metadata": {
        "accession": "PF01149",
        "entry_id": null,
        "type": "domain",
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        "source_database": "pfam",
        "member_databases": null,
        "integrated": "IPR012319",
        "hierarchy": null,
        "name": {
            "name": "Formamidopyrimidine-DNA glycosylase N-terminal domain",
            "short": "Fapy_DNA_glyco"
        },
        "description": [
            {
                "text": "<p>Formamidopyrimidine-DNA glycosylase (Fpg) is a DNA repair enzyme that excises oxidised purines from damaged DNA. This family is the N-terminal domain contains eight beta-strands, forming a beta-sandwich with two alpha-helices parallel to its edges [[cite:PUB00012853]].</p>",
                "llm": false,
                "checked": false,
                "updated": false
            }
        ],
        "wikipedia": null,
        "literature": {
            "PUB00012853": {
                "PMID": 11912217,
                "ISBN": null,
                "volume": "277",
                "issue": "22",
                "year": 2002,
                "title": "Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA.",
                "URL": null,
                "raw_pages": "19811-6",
                "medline_journal": "J Biol Chem",
                "ISO_journal": "J. Biol. Chem.",
                "authors": [
                    "Gilboa R",
                    "Zharkov DO",
                    "Golan G",
                    "Fernandes AS",
                    "Gerchman SE",
                    "Matz E",
                    "Kycia JH",
                    "Grollman AP",
                    "Shoham G."
                ],
                "DOI_URL": "http://dx.doi.org/10.1074/jbc.M202058200"
            }
        },
        "set_info": null,
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        "counters": {
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            "domain_architectures": 141,
            "interactions": 0,
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            "proteins": 56645,
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            "structural_models": {
                "alphafold": 42844
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            "structures": 116,
            "taxa": 35097
        },
        "entry_annotations": {
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        },
        "cross_references": {},
        "is_llm": false,
        "is_reviewed_llm": false,
        "is_updated_llm": false,
        "representative_structure": null
    }
}