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{
"metadata": {
"accession": "PF01149",
"entry_id": null,
"type": "domain",
"go_terms": null,
"source_database": "pfam",
"member_databases": null,
"integrated": "IPR012319",
"hierarchy": null,
"name": {
"name": "Formamidopyrimidine-DNA glycosylase N-terminal domain",
"short": "Fapy_DNA_glyco"
},
"description": [
{
"text": "<p>Formamidopyrimidine-DNA glycosylase (Fpg) is a DNA repair enzyme that excises oxidised purines from damaged DNA. This family is the N-terminal domain contains eight beta-strands, forming a beta-sandwich with two alpha-helices parallel to its edges [[cite:PUB00012853]].</p>",
"llm": false,
"checked": false,
"updated": false
}
],
"wikipedia": null,
"literature": {
"PUB00012853": {
"PMID": 11912217,
"ISBN": null,
"volume": "277",
"issue": "22",
"year": 2002,
"title": "Structure of formamidopyrimidine-DNA glycosylase covalently complexed to DNA.",
"URL": null,
"raw_pages": "19811-6",
"medline_journal": "J Biol Chem",
"ISO_journal": "J. Biol. Chem.",
"authors": [
"Gilboa R",
"Zharkov DO",
"Golan G",
"Fernandes AS",
"Gerchman SE",
"Matz E",
"Kycia JH",
"Grollman AP",
"Shoham G."
],
"DOI_URL": "http://dx.doi.org/10.1074/jbc.M202058200"
}
},
"set_info": null,
"overlaps_with": null,
"counters": {
"subfamilies": 0,
"domain_architectures": 141,
"interactions": 0,
"matches": 56693,
"pathways": 0,
"proteins": 56645,
"proteomes": 9180,
"sets": 0,
"structural_models": {
"alphafold": 42844
},
"structures": 116,
"taxa": 35097
},
"entry_annotations": {
"hmm": 0,
"logo": 0,
"alignment:seed": 591,
"alignment:full": 15370
},
"cross_references": {},
"is_llm": false,
"is_reviewed_llm": false,
"is_updated_llm": false,
"representative_structure": null
}
}