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EMD-17540
Cryo-EM structure of full-length human UBR5 (homotetramer)
EMD-17540
Single-particle3.87 Å
Deposition: 31/05/2023Map released: 14/06/2023
Last modified: 16/08/2023
Sample Organism:
Homo sapiens
Sample: Tetramer of UBR5
Fitted models: 8p83
Deposition Authors: Aguirre JD, Kater L, Kempf G, Cavadini S, Thoma NH
Sample: Tetramer of UBR5
Fitted models: 8p83
Deposition Authors: Aguirre JD, Kater L, Kempf G, Cavadini S, Thoma NH
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Tsai JM,
Aguirre JD,
Li YD ,
Brown J,
Focht V,
Kater L,
Kempf G,
Sandoval B,
Schmitt S,
Rutter JC,
Galli P,
Sandate CR ,
Cutler JA,
Zou C,
Donovan KA,
Lumpkin RJ,
Cavadini S,
Park PMC,
Sievers Q,
Hatton C,
Ener E,
Regalado BD,
Sperling MT,
Slabicki M,
Kim J,
Zon R,
Zhang Z,
Miller PG,
Belizaire R,
Sperling AS,
Fischer ES,
Irizarry R,
Armstrong SA,
Thoma NH ,
Ebert BL
(2023) Mol Cell , 83 , 2753
,
Brown J,
Focht V,
Kater L,
Kempf G,
Sandoval B,
Schmitt S,
Rutter JC,
Galli P,
Sandate CR ,
Cutler JA,
Zou C,
Donovan KA,
Lumpkin RJ,
Cavadini S,
Park PMC,
Sievers Q,
Hatton C,
Ener E,
Regalado BD,
Sperling MT,
Slabicki M,
Kim J,
Zon R,
Zhang Z,
Miller PG,
Belizaire R,
Sperling AS,
Fischer ES,
Irizarry R,
Armstrong SA,
Thoma NH ,
Ebert BL
(2023) Mol Cell , 83 , 2753