3.9 | | PIGQ | 'human intestinal organoids derived from H9 stem cells' vs 'Undifferentiated H9 Stem Cells' | cell type | Transcriptional Profiling of human pluripotent stem cells and and derived tissues |
-2.9 | | PIGQ | 'osteosarcoma' vs 'normal' | disease | Transcription profiling by array of human bone specimens from patients with osteosarcoma |
-2.4 | | PIGQ | 'EX00000246; stimulated with interferon gamma and lipopolysaccharide' vs 'none' at '6 hour' | compound, time, treatment | GPBAR1 agonism has a broad impact on blocking macrophage activation |
-2.4 | | PIGQ | 'P-bodies (cytosolic RNP granules)' vs 'pre-sorted fraction' | fraction | RNA-Seq of purified P-bodies from HEK293 cells |
-2.3 | | PIGQ | 'DMSO' in 'stimulated with interferon gamma and lipopolysaccharide' vs 'none' at '6 hour' | compound, time, treatment | GPBAR1 agonism has a broad impact on blocking macrophage activation |
-2.3 | | PIGQ | 'Human betacoronavirus 2c EMC/2012' vs 'mock' at '24 hour' | infect, time | Transcription profiling of human bronchial epithelial cell line Calu-3 2B4 infected with Human Coronavirus EMC 2012 |
-2.3 | | PIGQ | 'chronic kidney disease' vs 'normal' in 'validation set' | cohort, disease | Development of gene expression profiles in human chronic kidney disease |
2.1 | | PIGQ | 'sebaceous of Jadassohn nevus' vs 'normal' | block, disease | RNA-seq of a panel of non-melanoma skin cancer lesions |
-2.1 | | PIGQ | 'erythroleukemia; ZRSR2 shRNA' vs 'normal' | disease, genotype | RNA-seq of bone marrow from patients with myelodysplastic syndrome |
1.9 | | PIGQ | 'actinic keratosis' vs 'normal' | block, disease | RNA-seq of a panel of non-melanoma skin cancer lesions |
-1.9 | | PIGQ | 'colorectal carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
-1.9 | | PIGQ | 'pancreatic adenocarcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
1.8 | | PIGQ | 'squamous cell carcinoma' vs 'normal' | block, disease | RNA-seq of a panel of non-melanoma skin cancer lesions |
-1.8 | | PIGQ | 'DPPA5 knock-down' vs 'mock' | RNA interference | RNA-seq analysis of vorinostat-resistant HCT116 cells following gene knockdown of potential vorinostat-resistance candidate genes |
-1.8 | | PIGQ | 'Zaire ebolavirus lacking the mucin domain of GP' vs 'mock' at '8 hour' | infect, time | Human U937 cell transcriptome response to Zaire Ebola virus wild-type in the delta-VP30 background and delta-mucin virus |
1.7 | | PIGQ | 'cisplatin; 100 micromolar' vs 'none' in 'scrambled siRNA' | RNA interference, compound | RNA-seq of human head and neck cancer cell line SQD9 knock-out for TMEM45A exposed to cisplatin |
-1.7 | | PIGQ | 'Human betacoronavirus 2c EMC/2012; 18 hour' vs 'mock; 24 hour' | infect, time | Transcription profiling of human bronchial epithelial cell line Calu-3 2B4 infected with Human Coronavirus EMC 2012 |
-1.7 | | PIGQ | 'transplant rejection; borderline' vs 'normal; none' in 'kidney transplant' | clinical information, disease, disease staging | Expression of the IL-17/Th17 axis in the development of acute renal allograft rejection |
-1.6 | | PIGQ | 'expression of estrogen receptor beta fused to N terminus tandem affinity purification tag' vs 'expression of estrogen receptor alpha fused to C terminus tandem affinity purification tag' | genotype | The nuclear receptor ERbeta engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading. Part 4 |
1.6 | | PIGQ | '12 hour' vs '0 hour' in 'MCF-10A' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
1.6 | | PIGQ | 'valproic acid; 15 millimolar' vs 'control' at '3 day' | compound, sampling time point | RNA-seq of Primary Human Hepatocytes (PHH) exposed to Valproic Acid (VPA) for 3 days daily and 3 days daily exposure followed by 3 days washout. |
1.6 | | PIGQ | 'K-562; chronic myelogenous (blast crisis) leukemia; P01' vs 'K-562; chronic myelogenous (blast crisis) leukemia; P0' | cell line, disease, passage | Microarray analysis of xenograft models in use at the Developmental Therapeutics Program of the National Cancer Institute (DTP-NCI) |
-1.5 | | PIGQ | '501Mel; shBRG1 knockdown' vs '501Mel; control' | cell line, phenotype | BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq) |
-1.5 | | PIGQ | 'EX00000246' vs 'none' in 'unstimulated' at '6 hour' | compound, time, treatment | GPBAR1 agonism has a broad impact on blocking macrophage activation |
1.5 | | PIGQ | 'atopic eczema; normal skin' vs 'normal; normal skin' | clinical information, disease, phenotype | Transcription profiling by array of acute and chronic atopic dermatitis compared to normal skin |
1.5 | | PIGQ | 'K-562; chronic myelogenous (blast crisis) leukemia; P04' vs 'K-562; chronic myelogenous (blast crisis) leukemia; P0' | cell line, disease, passage | Microarray analysis of xenograft models in use at the Developmental Therapeutics Program of the National Cancer Institute (DTP-NCI) |
-1.5 | | PIGQ | 'transplant rejection; acute' vs 'normal; none' in 'kidney transplant' | clinical information, disease, disease staging | Expression of the IL-17/Th17 axis in the development of acute renal allograft rejection |
-1.5 | | PIGQ | 'myxosarcoma' vs 'normal' | disease | Atrial Myxomas Arise From Multipotent Myxoid Cardiac Stem Cells |
-1.4 | | PIGQ | 'Digoxin; 400 nanomolar' vs 'DMSO' | compound | Expression profiling of Jurkat cells infected with HIV-1 and treated with digoxin or DMSO |
1.4 | | PIGQ | '12 hour' vs '0 hour' in 'MCF-10A-H1047R' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
1.4 | | PIGQ | '24 hour' vs '0 hour' in 'MCF-10A-H1047R' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
1.4 | | PIGQ | 'suberoylanilide hydroxamic acid' vs 'control' | compound | Vascular histone deacetylation by pharmacological HDAC inhibition [SAHA, RNA-seq] |
1.4 | | PIGQ | 'MDAMB231; cocultured with fibroblast CCD1112Sk' vs 'MDAMB231; normal' | cell line, growth condition | System-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity |
1.4 | | PIGQ | 'trichostatin A; 500 nanomolar' vs 'control' | compound | Transcription profiling by high throughput sequencing of human aortic endothelial cell treated with TSA |
-1.4 | | PIGQ | 'kidney transplant; transplant rejection; borderline' vs 'none; normal; none' | clinical information, disease, disease staging | Expression of the IL-17/Th17 axis in the development of acute renal allograft rejection |
-1.3 | | PIGQ | 'PAX2 siRNA' vs 'control' | RNA interference | Transcription profiling by high throughput sequencing of control- and PAX2-siRNA-transfected human epididymis epithelial cells |
-1.3 | | PIGQ | 'expression of estrogen receptor beta fused to C terminus tandem affinity purification tag' vs 'expression of estrogen receptor alpha fused to C terminus tandem affinity purification tag' | genotype | The nuclear receptor ERbeta engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading. Part 4 |
1.3 | | PIGQ | 'SNCA overexpression' vs 'wild type genotype' | genotype | RNA-seq of human midbrain organoid models of Parkinson's Disease |
-1.3 | | PIGQ | 'EX00000246' vs 'none' in 'unstimulated' at '24 hour' | compound, time, treatment | GPBAR1 agonism has a broad impact on blocking macrophage activation |
1.3 | | PIGQ | 'POLR2D knock-down' vs 'mock' | RNA interference | RNA-seq analysis of vorinostat-resistant HCT116 cells following gene knockdown of potential vorinostat-resistance candidate genes |
-1.3 | | PIGQ | 'tongue squamous cell carcinoma' vs 'normal' in 'vehicle' | compound, disease | Transcription profiling by high throughput sequencing of retinoic acid treated human oral squamous cell carcinoma cells and normal cells |
1.3 | | PIGQ | 'blood alcohol content 0%' vs 'control' in 'time point 1' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
1.3 | | PIGQ | 'blood alcohol content 0.04%rising' vs 'control' in 'time point 2' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
-1.3 | | PIGQ | 'tumor necrosis factor alpha' vs 'none' in 'brain microvascular endothelial cell; co-culture' | cell type, growth condition, stimulus | Reactive astrocytes transduce blood-brain barrier inflammation through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin |
1.3 | | PIGQ | '24 hours with hMSC Adipogenic Differentiation Bullet Kit' vs 'none' in 'polysome' | fraction, protocol | RNA-seq of total RNA from human adipose tissue stem cells induced to adipogenesis and osteogenesis for 24 hours |
1.3 | | PIGQ | 'sepsis' vs 'normal' in 'whole blood' | cell type, disease, treatment | Next generation sequencing of human immune cell subsets across diseases |
-1.3 | | PIGQ | 'ssON; 0.5 micromolar' vs 'none' in 'none; none' | compound, infect, stimulus | RNA-seq of H1N1 infected monocyte-derived dendritic cells (MoDC), stimulated with single-stranded oligonucleotides (ssON) and/or Poly I:C. |
-1.2 | | PIGQ | 'CD3/CD28 beads' vs 'none' in 'none' | stimulus, xenograft | RNA-Seq of T cells sorted from human PBMCs, or from T cells stimulated with CD3/CD28 beads for 4 days, or from the spleen of NSG or NSG-HLA-A2/HHD mice, 7 days after transplantation with human PBMCs |
1.2 | | PIGQ | 'cisplatin; 100 micromolar' vs 'none' in 'TMEM45A knockdown by siRNA' | RNA interference, compound | RNA-seq of human head and neck cancer cell line SQD9 knock-out for TMEM45A exposed to cisplatin |
1.2 | | PIGQ | '24 hour' vs '0 hour' in 'MCF-10A' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
1.2 | | PIGQ | 'Cal51; cocultured with fibroblast HFF1' vs 'Cal51; normal' | cell line, growth condition | System-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity |
1.2 | | PIGQ | 'MDAMB231; cocultured with fibroblast HFF1' vs 'MDAMB231; normal' | cell line, growth condition | System-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity |
-1.2 | | PIGQ | 'ribavirin 100 microgram per milliliter' vs 'phosphate buffered saline' | compound, dose | Transcription profiling by array of human Huh7 cells after treatment with ribavirin |
1.2 | | PIGQ | 'UV' vs 'none' in 'brct expression' | phenotype, stimulus | Transcriptional profiling by array of U2OS cells overexpressing the BRCT domain of PARP1 after UV radiation |
-1.2 | | PIGQ | 'THZ1 (35 nanomolar)' vs 'none' | compound | RNA-seq of IMR-5/75 neuroblastoma cell line treated with JQ1, THZ1 or combination against untreated controls |
1.2 | | PIGQ | 'definitive endoderm differentiated from H9 stem cells' vs 'Undifferentiated H9 Stem Cells' | cell type | Transcriptional Profiling of human pluripotent stem cells and and derived tissues |
-1.2 | | PIGQ | 'hepatobiliary carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
1.1 | | PIGQ | 'blood alcohol content 0.08%' vs 'control' in 'time point 3' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
1.1 | | PIGQ | 'blood alcohol content 0.04%declining' vs 'control' in 'time point 4' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
1.1 | | PIGQ | 'Cal51; cocultured with fibroblast CCD1112Sk' vs 'Cal51; normal' | cell line, growth condition | System-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity |
-1.1 | | PIGQ | 'kidney transplant; transplant rejection; acute' vs 'none; normal; none' | clinical information, disease, disease staging | Expression of the IL-17/Th17 axis in the development of acute renal allograft rejection |
1.1 | | PIGQ | 'blood alcohol content 0.02%declining' vs 'control' in 'time point 5' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
-1.1 | | PIGQ | 'Hypoxia' vs 'Normoxia' in 'A2780; None' | cell line, compound, growth condition | Analysis of gene expression changes in response to hypoxia and/or cisplatin in A2780 and A2780cis cells |
-1.1 | | PIGQ | 'DMSO' in 'stimulated with interferon gamma and lipopolysaccharide' vs 'none' at '24 hour' | compound, time, treatment | GPBAR1 agonism has a broad impact on blocking macrophage activation |
1.1 | | PIGQ | 'KM12; adenocarcinoma of colon; P04' vs 'KM12; adenocarcinoma of colon; P0' | cell line, disease, passage | Microarray analysis of xenograft models in use at the Developmental Therapeutics Program of the National Cancer Institute (DTP-NCI) |
-1.1 | | PIGQ | 'HTB56; highly metastatic' vs 'HTB56; normal' | cell line, phenotype | Changes in global gene expression in lung cancer cell lines A549 (A) and HTB56 (H) [Affymetrix microarrays] |
1.1 | | PIGQ | 'RXF 393; poorly differentiated hypernephroma; P10' vs 'RXF 393; poorly differentiated hypernephroma; P0' | cell line, disease, passage | Microarray analysis of xenograft models in use at the Developmental Therapeutics Program of the National Cancer Institute (DTP-NCI) |
-1.1 | | PIGQ | 'tumor necrosis factor alpha' vs 'none' in 'brain microvascular endothelial cell; monoculture' | cell type, growth condition, stimulus | Reactive astrocytes transduce blood-brain barrier inflammation through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin |
-1.1 | | PIGQ | 'triple-negative breast cancer; breast carcinoma' vs 'normal' | clinical information, disease | RNA-seq of 17 breast tumor samples of three different subtypes and normal human breast organoids samples |
-1 | | PIGQ | 'estrogen receptor alpha shRNA' vs 'scrambled shRNA' | RNA interference | RNA-seq of the human breast cancer ERα-suppressed MCF-7(MCF-7/SP10+) cells and of their internal control MCF-7 (MCF-7/C) cells |
-1 | | PIGQ | 'T3; 100 nanomolar' vs 'none' in 'derived neural cell; correction to MCT8[wt]' | cell type, compound, genotype | RNA-seq analysis of MCT8-deficient and healthy control brain microvascular endothelial cells (BMECs) and neural cells |
-1 | | PIGQ | 'T3; 100 nanomolar' vs 'none' in 'derived neural cell; MCT8[P321L]' | cell type, compound, genotype | RNA-seq analysis of MCT8-deficient and healthy control brain microvascular endothelial cells (BMECs) and neural cells |
-1 | | PIGQ | 'Human betacoronavirus 2c England-Qatar/2012; 24 hour' vs 'mock; 18 hour' | infect, time | Transcription profiling of human bronchial epithelial cell line Calu-3 2B4 infected with Human Coronavirus MERS-CoV-London |
1 | | PIGQ | '8 day' vs '0 day' | time | Global expression profiling time series of early human embryonic stem cell differentiation towards the mesoderm lineage |
1 | | PIGQ | '10 day' vs '0 day' | time | Global expression profiling time series of early human embryonic stem cell differentiation towards the mesoderm lineage |
1 | | PIGQ | '5 day' vs '0 day' | time | Global expression profiling time series of early human embryonic stem cell differentiation towards the mesoderm lineage |
1 | | PIGQ | '6 day' vs '0 day' | time | Global expression profiling time series of early human embryonic stem cell differentiation towards the mesoderm lineage |
1 | | PIGQ | '9 day' vs '0 day' | time | Global expression profiling time series of early human embryonic stem cell differentiation towards the mesoderm lineage |
1 | | PIGQ | 'valproic acid; 15 millimolar' vs 'control' at '2 day' | compound, sampling time point | RNA-seq of Primary Human Hepatocytes (PHH) exposed to Valproic Acid (VPA) for 3 days daily and 3 days daily exposure followed by 3 days washout. |
-1 | | PIGQ | 'PSMD13 knock-down' vs 'mock' | RNA interference | RNA-seq analysis of vorinostat-resistant HCT116 cells following gene knockdown of potential vorinostat-resistance candidate genes |
