-5.6 | | FBXW7 | 'Pcolce siRNA' vs 'scrambled siRNA' | RNA interference | RNA-seq of human hypertrophic scar fibroblast cell treated with pcolce siRNA against untreated controls |
-3.8 | | FBXW7 | 'Ataxia-telangiectasia' vs 'normal' | disease | Ataxia-telangiectasia cerebellar cortex expression |
-3.2 | | FBXW7 | 'glioblastoma' vs 'control' | block, disease | DNA Methylation Profiling of Glioblastoma: Impact on Gene Expression and Clinical Outcome (Agilent Expression Study) |
3.1 | | FBXW7 | '154; 1 micromolar' vs 'DMSO' | compound | Development of a small molecule for treatment of castration resistant prostate cancer via androgen receptor and IL6/STAT3 pathways |
-2.7 | | FBXW7 | 'pilocytic astrocytoma' vs 'normal' | disease | Gene expression profile of pediatric and adult brain tumor types and normal brain |
-2.7 | | FBXW7 | 'supratentorial ependymoma' vs 'normal' | disease | Gene expression profile of pediatric and adult brain tumor types and normal brain |
-2.7 | | FBXW7 | 'medulloblastoma, large-cell' vs 'normal' | disease | Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes |
-2.6 | | FBXW7 | 'contrast-enhancing core; glioma' vs 'normal' | biopsy site, disease | Transcription profiling by high throughput sequencing in the margins of glioblastoma |
2.6 | | FBXW7 | 'P-bodies (cytosolic RNP granules)' vs 'pre-sorted fraction' | fraction | RNA-Seq of purified P-bodies from HEK293 cells |
-2.6 | | FBXW7 | 'posterior fossa group B ependymoma' vs 'normal' | disease | Gene expression profile of pediatric and adult brain tumor types and normal brain |
-2.6 | | FBXW7 | 'adult high grade glioma' vs 'normal' | disease | Gene expression profile of pediatric and adult brain tumor types and normal brain |
-2.5 | | FBXW7 | 'posterior fossa group A ependymoma' vs 'normal' | disease | Gene expression profile of pediatric and adult brain tumor types and normal brain |
2.4 | | FBXW7 | 'lung carcinoma' vs 'normal' | biopsy site, disease | Gene expression profiling of the adjacent airway field cancerization in early stage NSCLC |
-2.4 | | FBXW7 | 'lurbinectedin; 10 nanomolar' vs 'none' | compound | Whole transcriptome profiling by microarray of monocytes stimulated with LPS and treated with trabectedin, lurbinectedin or doxorubicin |
-2.4 | | FBXW7 | 'cultured skin substitute; 3 day' vs 'skin; 0 day' | organism part, time | Transcription profiling by array of human grafted engineered skin substitutes |
-2.4 | | FBXW7 | 'ependymoma' vs 'normal' | disease | gene expression profiling of three type of grade II gliomas |
-2.4 | | FBXW7 | 'astrocytic glioma' vs 'normal' | disease | gene expression profiling of three type of grade II gliomas |
-2.3 | | FBXW7 | 'erythroleukemia; ZRSR2 shRNA' vs 'normal' | disease, genotype | RNA-seq of bone marrow from patients with myelodysplastic syndrome |
-2.3 | | FBXW7 | 'pediatric high grade glioma' vs 'normal' | disease | Gene expression profile of pediatric and adult brain tumor types and normal brain |
2.3 | | FBXW7 | '154; 0.4 micromolar' vs 'DMSO' | compound | Development of a small molecule for treatment of castration resistant prostate cancer via androgen receptor and IL6/STAT3 pathways |
2.3 | | FBXW7 | 'SARS coronavirus Urbani ΔORF6 mutant' vs 'mock' at '48 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
2.3 | | FBXW7 | 'SARS coronavirus Urbani ΔORF6 mutant' vs 'mock' at '54 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
-2.3 | | FBXW7 | 'glioblastoma' vs 'normal' | disease | Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes |
-2.2 | | FBXW7 | 'blood alcohol content 0.04%declining' vs 'control' in 'time point 4' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
2.2 | | FBXW7 | 'SARS coronavirus Urbani ΔORF6 mutant' vs 'mock' at '60 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
-2.2 | | FBXW7 | 'sonic hedgehog group medulloblastoma' vs 'normal' | disease | Gene expression profile of pediatric and adult brain tumor types and normal brain |
-2.2 | | FBXW7 | 'group 4 medulloblastoma' vs 'normal' | disease | Gene expression profile of pediatric and adult brain tumor types and normal brain |
-2.2 | | FBXW7 | 'trabectedin; 10 nanomolar' vs 'none' | compound | Whole transcriptome profiling by microarray of monocytes stimulated with LPS and treated with trabectedin, lurbinectedin or doxorubicin |
-2.2 | | FBXW7 | 'glioblastoma' vs 'normal' | disease | Transcription profiling of human grade II astrocytic tumor (astrocytomas) vs grade IV tumors (glioblastoma) |
-2.2 | | FBXW7 | 'group 3 medulloblastoma' vs 'normal' | disease | Gene expression profile of pediatric and adult brain tumor types and normal brain |
2.2 | | FBXW7 | 'wild type; BREFELDIN A' vs 'wild type; control' | genotype, treatment | Induction of ER stress in HCT116 colon cancer cells |
-2.1 | | FBXW7 | 'ependymoma' vs 'normal' | disease | Expression data from human brain tumors and human normal brain |
-2.1 | | FBXW7 | 'blood alcohol content 0.04%rising' vs 'control' in 'time point 2' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
-2.1 | | FBXW7 | 'medulloblastoma' vs 'normal' | disease | Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes |
2.1 | | FBXW7 | 'GLV-1h153' at '24 hour' vs 'control' | infect, time | Expression data from human pancreatic cells PANC-1 infected with oncolytic vaccinia virus GLV-1h153 |
-2.1 | | FBXW7 | 'Astrocytoma, Pilocytic' vs 'normal' | disease | Expression data from human brain tumors and human normal brain |
-2.1 | | FBXW7 | 'cultured skin substitute; 14 day' vs 'skin; 0 day' | organism part, time | Transcription profiling by array of human grafted engineered skin substitutes |
-2 | | FBXW7 | 'blood alcohol content 0.08%' vs 'control' in 'time point 3' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
-2 | | FBXW7 | 'P0 cells' vs 'untreated P4 cells' | passage, treatment | Transcription profiling by high throughput sequencing of human fetal differentiated P0 retinal pigment epithelial cells, mesenchymal P4 cells, and A-83-01 rescued P4 cells |
-2 | | FBXW7 | 'cultured skin substitute; 7 day' vs 'skin; 0 day' | organism part, time | Transcription profiling by array of human grafted engineered skin substitutes |
-1.9 | | FBXW7 | 'blood alcohol content 0.02%declining' vs 'control' in 'time point 5' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
1.8 | | FBXW7 | 'dexamethasone; 1 micromolar' vs 'vehicle' | compound | RNA-seq in GR18 cell line to identify genes regulated by the Glucocorticoid Receptor (24h treatment) |
-1.8 | | FBXW7 | 'oligodendroglioma' vs 'normal' | disease | Molecular Analysis of Brain Neoplasia |
-1.8 | | FBXW7 | 'blood alcohol content 0%' vs 'control' in 'time point 1' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
1.8 | | FBXW7 | 'SARS coronavirus Urbani ΔORF6 mutant' vs 'mock' at '36 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
1.8 | | FBXW7 | 'cisplatin' at '24 hour' vs 'none' at '0 hour' | compound, time | Transcription profiling by array of human U87 cells treated with cytotoxic anticancer drug cisplatin or a ruthenium-based compound for 6 or 24 hours compared to untreated controls |
-1.8 | | FBXW7 | 'medulloblastoma' vs 'normal' | disease | Expression data from human brain tumors and human normal brain |
1.8 | | FBXW7 | 'CCRF-CEM; acute lymphoblastic (T-ALL) leukemia; P04' vs 'CCRF-CEM; acute lymphoblastic (T-ALL) leukemia; P0' | cell line, disease, passage | Microarray analysis of xenograft models in use at the Developmental Therapeutics Program of the National Cancer Institute (DTP-NCI) |
-1.8 | | FBXW7 | 'ovarian cancer' vs 'normal' in 'epithelial cell' | cell type, disease | A cancer associated fibroblasts (CAFs) specific gene signature in high grade serous ovarian cancer |
-1.8 | | FBXW7 | 'atypical teratoid/rhabdoid tumor' vs 'normal' | disease | Gene expression profile of pediatric and adult brain tumor types and normal brain |
-1.8 | | FBXW7 | 'atypical teratoid / rhabdoid tumor' vs 'normal' | disease | Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes |
-1.8 | | FBXW7 | 'astrocytoma' vs 'normal' | disease | Transcription profiling of human grade II astrocytic tumor (astrocytomas) vs grade IV tumors (glioblastoma) |
-1.7 | | FBXW7 | 'glioblastoma multiforme' vs 'normal' | disease | Molecular Analysis of Brain Neoplasia |
-1.7 | | FBXW7 | 'astrocytoma' vs 'normal' | disease | Molecular Analysis of Brain Neoplasia |
-1.7 | | FBXW7 | 'cisplatin; 100 micromolar' vs 'none' in 'scrambled siRNA' | RNA interference, compound | RNA-seq of human head and neck cancer cell line SQD9 knock-out for TMEM45A exposed to cisplatin |
-1.7 | | FBXW7 | 'glioblastoma' vs 'normal' | disease | Expression data from human brain tumors and human normal brain |
1.7 | | FBXW7 | 'SARS coronavirus Urbani ΔORF6 mutant' vs 'mock' at '72 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
-1.7 | | FBXW7 | 'ejaculatory azoospermia; Johnsen score count 2' vs 'ejaculatory azoospermia; Johnsen score count 5' | disease, histology | Transcription profiling of human testis samples from men with highly defined and homogenous testicular pathologies reveals patterns that correlate with distinct stages of spermatogenesis |
1.7 | | FBXW7 | 'dexamethasone; 1 micromolar' vs 'DMSO' in 'SUP-B15' | cell line, compound | Glucocorticoids induced transcriptional regulation in acute lymphoblastic leukemia |
-1.7 | | FBXW7 | 'oligodendroglioma' vs 'normal' | disease | gene expression profiling of three type of grade II gliomas |
-1.6 | | FBXW7 | 'cisplatin; 100 micromolar' vs 'none' in 'TMEM45A knockdown by siRNA' | RNA interference, compound | RNA-seq of human head and neck cancer cell line SQD9 knock-out for TMEM45A exposed to cisplatin |
-1.6 | | FBXW7 | 'non-small cell lung carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
-1.6 | | FBXW7 | 'sulforaphane; prostate carcinoma' at '24 hour' vs 'sulforaphane; normal' at '24 hour' | compound, disease, time | Genome-wide transcriptome analysis of the dietary chemopreventive phytochemical sulforaphane on normal and prostate cancer cells. |
1.6 | | FBXW7 | 'CCRF-CEM; acute lymphoblastic (T-ALL) leukemia; P01' vs 'CCRF-CEM; acute lymphoblastic (T-ALL) leukemia; P0' | cell line, disease, passage | Microarray analysis of xenograft models in use at the Developmental Therapeutics Program of the National Cancer Institute (DTP-NCI) |
1.6 | | FBXW7 | 'Human betacoronavirus 2c England-Qatar/2012; 24 hour' vs 'mock; 18 hour' | infect, time | Transcription profiling of human bronchial epithelial cell line Calu-3 2B4 infected with Human Coronavirus MERS-CoV-London |
1.6 | | FBXW7 | 'gestational week 16' vs 'gestational week 9' | developmental stage | RNA-Seq of human fetal hearts at 9, 12 and 16 weeks of gestation |
-1.6 | | FBXW7 | 'primitive neuroectodermal tumor' vs 'normal' | disease | Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes |
-1.6 | | FBXW7 | 'monocyte; meningococcal sepsis' at '0 hour' vs 'monocyte; normal' at '0 hour' | cell type, disease, organism part, sampling time point | Transcription profiling by array of human peripheral blood cells from meningococcal sepsis patients sampled at various time points |
-1.6 | | FBXW7 | 'lesional' vs 'non-lesional' in 'one-cycle cDNA synthesis from bulk tissue' | phenotype, protocol | Combined Use of Laser Capture Microdissection and Microarray Analysis Identifies Locally Expressed Disease-Related Genes in Focal Regions of Psoriasis Vulgaris Skin Lesions |
1.5 | | FBXW7 | 'doxycycline; 0.5 microgram per milliliter; Day 3 post Neurogenin induction' vs 'control' | compound, treatment | Rapid neurogenesis through transcriptional activation in human stem cell (RNA-Seq) |
1.5 | | FBXW7 | 'JQ1 (1 micromolar) and THZ1 (35 nanomolar)' vs 'none' | compound | RNA-seq of IMR-5/75 neuroblastoma cell line treated with JQ1, THZ1 or combination against untreated controls |
-1.5 | | FBXW7 | 'RRx-1; 20 micromolar' vs 'none' | compound | RNA-seq of Huh7 cell after G6PD enzyme activity inhibitor RRx-1 treated with 20μM concentrations for 24h |
1.5 | | FBXW7 | 'ulcerative colitis, inflammation' vs 'normal, normal tissue' in 'colon' | disease, organism part, sampling site | RNA-seq of biopsies, crypts and organoids of inflamed and non-inflamed biopsies of ulcerative colitis patients |
-1.5 | | FBXW7 | 'phymatous rosacea' vs 'healthy' | clinical information | Transcription profiling of three cutaneous rosacea subtypes to characterize the inflammatory infiltrate |
1.5 | | FBXW7 | 'Nutlin; 5 micromolar' vs 'DMSO; 0.065 percent' in 'GL2' | RNA interference, compound | Expression data of A375 melanoma cells after DMSO or MLN4924 +/- Nutlin treatment for 26 hours |
-1.5 | | FBXW7 | 'non-triple-negative breast cancer; breast carcinoma' vs 'normal' | clinical information, disease | RNA-seq of 17 breast tumor samples of three different subtypes and normal human breast organoids samples |
1.5 | | FBXW7 | 'poly I:C' vs 'mock' in 'ncgRNA' | genotype, stimulus | Effects of innate immune stimuli on PAF1 knockout cells |
-1.5 | | FBXW7 | 'ejaculatory azoospermia; Johnsen score count 2' vs 'ejaculatory azoospermia; Johnsen score count 7' | disease, histology | Transcription profiling of human testis samples from men with highly defined and homogenous testicular pathologies reveals patterns that correlate with distinct stages of spermatogenesis |
-1.5 | | FBXW7 | 'hyperglycemic condition' vs 'non-diabetic condition' | clinical information | Transcription profiling by array of human pancreatic beta cells transplanted into mice |
-1.5 | | FBXW7 | 'post full confluence' vs 'early cell adhesion' | sampling time point | Transcription profiling by array of human osteogenic cells at different stages of the differentiation process |
-1.4 | | FBXW7 | 'breast cancer' vs 'normal' | disease | Gene expression profiling of LCM captured breast cancer cells |
-1.4 | | FBXW7 | '12 hour' vs '0 hour' in 'MCF-10A-H1047R' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
1.4 | | FBXW7 | 'HDAC1 homozygous knockout' vs 'wild type' | phenotype | RNA-seq of human near-haploid cell line HAP1 with CRISPR-edited frameshift mutations |
-1.4 | | FBXW7 | 'sebaceous of Jadassohn nevus' vs 'normal' | block, disease | RNA-seq of a panel of non-melanoma skin cancer lesions |
-1.4 | | FBXW7 | 'papulopustular rosacea' vs 'healthy' | clinical information | Transcription profiling of three cutaneous rosacea subtypes to characterize the inflammatory infiltrate |
1.4 | | FBXW7 | 'doxorubicin; 0.6 microgram per milliliter' vs 'none' | compound | Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells (Affymetrix) |
-1.4 | | FBXW7 | 'ejaculatory azoospermia; Johnsen score count 2' vs 'normal; Johnsen score count 10' | disease, histology | Transcription profiling of human testis samples from men with highly defined and homogenous testicular pathologies reveals patterns that correlate with distinct stages of spermatogenesis |
1.4 | | FBXW7 | 'prednisolone; 2 micromolar' vs 'DMSO' in 'SUP-B15' | cell line, compound | Glucocorticoids induced transcriptional regulation in acute lymphoblastic leukemia |
-1.4 | | FBXW7 | 'Newcastle disease virus' at '14 hour' vs 'none' at '0 hour' | infect, time | Transcription profiling by array of human dendritic cells infected with Newcastle Disease Virus |
1.4 | | FBXW7 | 'SARS coronavirus Urbani' vs 'mock' at '54 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
1.4 | | FBXW7 | 'p53KO; tunicamycin' vs 'p53KO; control' | genotype, treatment | Induction of ER stress in HCT116 colon cancer cells |
1.3 | | FBXW7 | 'PRPF8' vs 'control' | RNA interference | Regulation of constitutive and alternative messenger RNA splicing across the human transcriptome by PRPF8 is determined by 5' splice site strength |
-1.3 | | FBXW7 | 'CD3/CD28 beads' vs 'none' in 'none' | stimulus, xenograft | RNA-Seq of T cells sorted from human PBMCs, or from T cells stimulated with CD3/CD28 beads for 4 days, or from the spleen of NSG or NSG-HLA-A2/HHD mice, 7 days after transplantation with human PBMCs |
1.3 | | FBXW7 | '50 uM Enterobactin' vs 'control' | treatment | Effects of Lipocalin 2 (Lcn2), iron, and the bacterial siderophore Enterobactin on A549 respiratory cell gene expression |
1.3 | | FBXW7 | 'Nutlin-3; 10 micromolar' vs 'DMSO; 0.1 percent' | compound | Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells (Affymetrix) |
1.3 | | FBXW7 | 'SARS coronavirus Urbani ΔORF6 mutant' vs 'mock' at '30 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
1.3 | | FBXW7 | 'SARS coronavirus Urbani' vs 'mock' at '36 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
1.3 | | FBXW7 | 'SARS coronavirus Urbani' vs 'mock' at '48 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
-1.3 | | FBXW7 | 'ochratoxin A; 130 nanomolar' vs 'none' at '1 day' | compound, time | Microarray mRNA data of RPTEC/TERT1 cells exposed to nephrotoxic chemicals ochratoxin A and potassium bromate |
-1.3 | | FBXW7 | 'ejaculatory azoospermia; Johnsen score count 2' vs 'ejaculatory azoospermia; Johnsen score count 8' | disease, histology | Transcription profiling of human testis samples from men with highly defined and homogenous testicular pathologies reveals patterns that correlate with distinct stages of spermatogenesis |
1.3 | | FBXW7 | 'doxorubicin; 450 micromole per liter' vs 'none' at '2 day' | compound, sampling time point | Transcription profiling by array to investigate doxorubicin-induced toxicity in human cardiomyocytes derived from embryonic stem cell line SA121 |
1.3 | | FBXW7 | 'chronic kidney disease' vs 'normal' in 'validation set' | cohort, disease | Development of gene expression profiles in human chronic kidney disease |
1.3 | | FBXW7 | 'ovarian cancer' vs 'normal' in 'stromal cell' | cell type, disease | A cancer associated fibroblasts (CAFs) specific gene signature in high grade serous ovarian cancer |
-1.3 | | FBXW7 | 'monocyte; meningococcal sepsis' at '8 hour' vs 'monocyte; normal' at '0 hour' | cell type, disease, organism part, sampling time point | Transcription profiling by array of human peripheral blood cells from meningococcal sepsis patients sampled at various time points |
-1.3 | | FBXW7 | 'full confluence' vs 'early cell adhesion' | sampling time point | Transcription profiling by array of human osteogenic cells at different stages of the differentiation process |
1.3 | | FBXW7 | 'multiple myeloma' vs 'normal' in 'plasma cells' | cell type, disease | Gene expression profiling of B lymphocytes and plasma cells from Waldenstrons macroglobulinemia. |
1.2 | | FBXW7 | 'THZ1 (35 nanomolar)' vs 'none' | compound | RNA-seq of IMR-5/75 neuroblastoma cell line treated with JQ1, THZ1 or combination against untreated controls |
-1.2 | | FBXW7 | 'estrogen receptor alpha shRNA' vs 'scrambled shRNA' | RNA interference | RNA-seq of the human breast cancer ERα-suppressed MCF-7(MCF-7/SP10+) cells and of their internal control MCF-7 (MCF-7/C) cells |
-1.2 | | FBXW7 | 'stem cell from lung adenocarcinoma cell' vs 'stem cell from normal lung epithelial cell' | cell type | transcription profiling by array of stem cells isolated from non-small cell lung cancer cell lines (NCI-H2170 and A549) and normal lung epithelial cell line (PHBEC) |
1.2 | | FBXW7 | 'HUVEC cell' vs 'placental mesenchymal progenitor' | cell type | Transcription profiling by array of human akt-activated endothelial cells and mesenchymal progenitors to compare the cytokines and membrane factors that are differentially expressed |
-1.2 | | FBXW7 | 'erythematotelangiectatic rosacea' vs 'healthy' | clinical information | Transcription profiling of three cutaneous rosacea subtypes to characterize the inflammatory infiltrate |
1.2 | | FBXW7 | 'Cisplatin' vs 'None' in 'A2780; Normoxia' | cell line, compound, growth condition | Analysis of gene expression changes in response to hypoxia and/or cisplatin in A2780 and A2780cis cells |
-1.2 | | FBXW7 | 'non-enhancing margin; glioma' vs 'normal' | biopsy site, disease | Transcription profiling by high throughput sequencing in the margins of glioblastoma |
1.2 | | FBXW7 | 'doxorubicin; 450 micromole per liter' vs 'none' at '1 day' | compound, sampling time point | Transcription profiling by array to investigate doxorubicin-induced toxicity in human cardiomyocytes derived from embryonic stem cell line SA121 |
-1.2 | | FBXW7 | 'actinic keratosis' vs 'normal' | block, disease | RNA-seq of a panel of non-melanoma skin cancer lesions |
-1.2 | | FBXW7 | 'ejaculatory azoospermia; Johnsen score count 3.2' vs 'ejaculatory azoospermia; Johnsen score count 5' | disease, histology | Transcription profiling of human testis samples from men with highly defined and homogenous testicular pathologies reveals patterns that correlate with distinct stages of spermatogenesis |
1.2 | | FBXW7 | 'mural granulosa cell' vs 'cumulus cell' | cell type | Transcription profiling by array of human cumulus and mural granulosa cells from pre-ovulatory follicles after controlled ovarian stimulation |
-1.2 | | FBXW7 | 'monocyte; meningococcal sepsis' at '24 hour' vs 'monocyte; normal' at '0 hour' | cell type, disease, organism part, sampling time point | Transcription profiling by array of human peripheral blood cells from meningococcal sepsis patients sampled at various time points |
-1.2 | | FBXW7 | 'Alzheimers disease' vs 'normal' in 'posterior cingulate cortex' | disease, organism part | Microarray analysis of six brain areas from Alzheimers disease patients and normal individuals |
-1.2 | | FBXW7 | 'Newcastle disease virus' at '12 hour' vs 'none' at '0 hour' | infect, time | Transcription profiling by array of human dendritic cells infected with Newcastle Disease Virus |
-1.2 | | FBXW7 | 'semiconfluence' vs 'early cell adhesion' | sampling time point | Transcription profiling by array of human osteogenic cells at different stages of the differentiation process |
1.2 | | FBXW7 | 'astrocyte overexpressing 4 genes' vs 'astrocyte' | phenotype | Transcription profiling by array of human primary astrocytes, cancer stem cells derived from astrocytes overexpressing various oncogenic and iPSC-inducing factors, glioma stem cells and gliblastomat cell line to compare their expression profiles and tumor-initiating capabilities |
1.1 | | FBXW7 | 'dexamethasone; 1 micromolar' vs 'ethanol' | compound | RNA-seq in GR18 cell line to identify genes regulated by the Glucocorticoid Receptor |
1.1 | | FBXW7 | 'Human gammaherpesvirus 4' at '14 day' vs 'none' at '0 day' | infect, time | Infection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection |
-1.1 | | FBXW7 | 'p63 knockdown by siRNA' vs 'scrambled siRNA' in 'BxPC-3' | RNA interference, cell line | RNA-seq of human pancreatic cell lines, L3.6pl and BxPC-3, upon knockdown of p63 for 48 hours compared to siControl |
-1.1 | | FBXW7 | '12 hour' vs '0 hour' in 'MCF-10A' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
-1.1 | | FBXW7 | '24 hour' vs '0 hour' in 'MCF-10A-H1047R' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
-1.1 | | FBXW7 | 'sulforaphane; prostate carcinoma' at '6 hour' vs 'sulforaphane; normal' at '6 hour' | compound, disease, time | Genome-wide transcriptome analysis of the dietary chemopreventive phytochemical sulforaphane on normal and prostate cancer cells. |
-1.1 | | FBXW7 | 'breast carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
-1.1 | | FBXW7 | 'Cal51; cocultured with fibroblast HFF1' vs 'Cal51; normal' | cell line, growth condition | System-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity |
-1.1 | | FBXW7 | 'pancreatic adenocarcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
-1.1 | | FBXW7 | 'colorectal carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
1.1 | | FBXW7 | 'Daunorubicin; 100 nanomolar' vs 'DMSO; 0.065 percent' in 'GL2' | RNA interference, compound | Expression data of A375 melanoma cells after DMSO or MLN4924 +/- Nutlin treatment for 26 hours |
1.1 | | FBXW7 | 'MLN4924; 650 nanomolar' vs 'DMSO; 0.065 percent' in 'GL2' | RNA interference, compound | Expression data of A375 melanoma cells after DMSO or MLN4924 +/- Nutlin treatment for 26 hours |
1.1 | | FBXW7 | 'Human betacoronavirus 2c England-Qatar/2012' vs 'mock' at '18 hour' | infect, time | Transcription profiling of human bronchial epithelial cell line Calu-3 2B4 infected with Human Coronavirus MERS-CoV-London |
1.1 | | FBXW7 | 'SARS coronavirus Urbani' vs 'mock' at '30 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
1.1 | | FBXW7 | 'panobinostat' vs 'none' in 'MOLT-4' | cell line, compound | Gene expression profile of acute lymphoblastic leukemia cell lines treated with panobinostat |
1.1 | | FBXW7 | 'Cisplatin' vs 'None' in 'A2780cis; Normoxia' | cell line, compound, growth condition | Analysis of gene expression changes in response to hypoxia and/or cisplatin in A2780 and A2780cis cells |
1.1 | | FBXW7 | 'Cisplatin' vs 'None' in 'A2780; Hypoxia' | cell line, compound, growth condition | Analysis of gene expression changes in response to hypoxia and/or cisplatin in A2780 and A2780cis cells |
1.1 | | FBXW7 | 'atopic eczema; normal skin' vs 'normal; normal skin' | clinical information, disease, phenotype | Transcription profiling by array of acute and chronic atopic dermatitis compared to normal skin |
1.1 | | FBXW7 | 'ulcer; interstitial cystitis' vs 'normal' | clinical information, disease | Transcription profiling by array of bladder tissue of patients with interstitial cystitis |
-1.1 | | FBXW7 | 'hepatobiliary carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
-1.1 | | FBXW7 | 'cultured skin substitute; 28 day' vs 'skin; 0 day' | organism part, time | Transcription profiling by array of human grafted engineered skin substitutes |
-1.1 | | FBXW7 | 'DMSO; prostate carcinoma' at '24 hour' vs 'DMSO; normal' at '24 hour' | compound, disease, time | Genome-wide transcriptome analysis of the dietary chemopreventive phytochemical sulforaphane on normal and prostate cancer cells. |
-1.1 | | FBXW7 | 'cutaneous lupus erythematosus' vs 'normal' in 'Ovation RNA Amplification V2 kit' | disease, protocol | Dominant Th1 and Minimal Th17 Skewing in Discoid Lupus Revealed by Transcriptomic Comparison with Psoriasis |
-1.1 | | FBXW7 | 'Down syndrome' vs 'normal' | disease | Transcription profiling of human adult postmortem brain tissue from Down syndrome and healthy control subjects |
1.1 | | FBXW7 | 'response to RAF265 treatment; BRAF mutant' vs 'response to RAF265 treatment; wild type' | clinical information, genotype | Gene expression data from human metastatic melanoma tumors that may predict response to RAF265 |
-1.1 | | FBXW7 | 'lesional' vs 'non-lesional' in 'two-cycle cDNA synthesis from bulk tissue' | phenotype, protocol | Combined Use of Laser Capture Microdissection and Microarray Analysis Identifies Locally Expressed Disease-Related Genes in Focal Regions of Psoriasis Vulgaris Skin Lesions |
-1.1 | | FBXW7 | 'PAF1 knockout' vs 'ncgRNA' in 'poly I:C' | genotype, stimulus | Effects of innate immune stimuli on PAF1 knockout cells |
-1.1 | | FBXW7 | 'glioblastoma surrounding tissue' vs 'control' | histology | Candidate genes for the recurrence of glioblastoma multiforme identified by microarray |
1 | | FBXW7 | 'embryonic stem cell differentiating toward definitive endoderm; 48 hour' vs 'embryonic stem cell; 0 hour' | cell type, time | RNA-seq of definitive endoderm differentiation of human embryonic stem cells in early G1 phase of the cell cycle |
1 | | FBXW7 | 'embryonic stem cell differentiating toward definitive endoderm; 36 hour' vs 'embryonic stem cell; 0 hour' | cell type, time | RNA-seq of definitive endoderm differentiation of human embryonic stem cells in early G1 phase of the cell cycle |
1 | | FBXW7 | 'embryonic stem cell differentiating toward definitive endoderm; 60 hour' vs 'embryonic stem cell; 0 hour' | cell type, time | RNA-seq of definitive endoderm differentiation of human embryonic stem cells in early G1 phase of the cell cycle |
-1 | | FBXW7 | 'injected in NSG mouse' vs 'none' in 'none' | stimulus, xenograft | RNA-Seq of T cells sorted from human PBMCs, or from T cells stimulated with CD3/CD28 beads for 4 days, or from the spleen of NSG or NSG-HLA-A2/HHD mice, 7 days after transplantation with human PBMCs |
1 | | FBXW7 | 'brain-derived neurotrophic factor' vs 'none' at '2 hour' | sampling time point, stimulus | RNA-seq of human neurons derived from H9 embryonic stem cell lines treated with BDNF, TrkB agonist ZEB 85 or NT4 against untreated controls |
-1 | | FBXW7 | 'Barrett’s esophagus; low-grade dysplasia' vs 'normal' | disease, disease staging | Whole transcriptome profiling of Esophageal adenocarcinoma and Barrett's |
-1 | | FBXW7 | '180 days after left ventricular assist device placement' vs 'control' | treatment | Identification of differentially expressed transcripts and pathways one week and six months following implant of left ventricular devices |
-1 | | FBXW7 | 'neoplasm' vs 'normal tissue adjacent to neoplasm' | sampling site | Global gene expression profiles of 10 gastric cancer (GC) samples and 10 gastric normal adjacent tissue (gNAT) samples |
-1 | | FBXW7 | 'NLRC4-Macrophage Activation Syndrome; prior to anakinra treatment' vs 'normal' | disease, treatment | An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome |
-1 | | FBXW7 | 'squamous cell carcinoma' vs 'normal' | block, disease | RNA-seq of a panel of non-melanoma skin cancer lesions |
1 | | FBXW7 | 'acetaminophen; 18 millimolar' vs 'none' in 'hSKP-HPC; normal; skin' | cell line, compound, disease, organism part | Gene expression data from acetaminophen-induced toxicity in human hepatic in vitro systems and clinical liver samples |
1 | | FBXW7 | 'Human betacoronavirus 2c EMC/2012' vs 'mock' at '24 hour' | infect, time | Transcription profiling of human bronchial epithelial cell line Calu-3 2B4 infected with Human Coronavirus EMC 2012 |
-1 | | FBXW7 | 'neoplasm' vs 'normal tissue adjacent to neoplasm' | sampling site | Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma |
-1 | | FBXW7 | 'SDC1-siRNA' vs 'control' | RNA interference | Genes regulated by SDC1 |
1 | | FBXW7 | 'CCRF-CEM; acute lymphoblastic (T-ALL) leukemia; P10' vs 'CCRF-CEM; acute lymphoblastic (T-ALL) leukemia; P0' | cell line, disease, passage | Microarray analysis of xenograft models in use at the Developmental Therapeutics Program of the National Cancer Institute (DTP-NCI) |
-1 | | FBXW7 | 'media with 10 mM lactic acid (pH 6.7) in hypoxia (1% pO2)' vs 'control' | growth condition | The genomic analysis of the interaction between the lactic acidosis and hypoxia response |
-1 | | FBXW7 | 'glioblastoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
1 | | FBXW7 | '24 hours with hMSC Osteogenic Bullet Kit' vs 'none' in 'total' | fraction, protocol | RNA-seq of total RNA from human adipose tissue stem cells induced to adipogenesis and osteogenesis for 24 hours |
1 | | FBXW7 | 'shZBTB4' vs 'scrambled control' | RNA interference | RNAi knock down of mSin3a-b and SBTB4 in human colon carcinoma cell line HCT116 |
1 | | FBXW7 | '10 micromolar; Nutlin-3' vs 'DMSO control' | compound | Transcription profiling by array of human HCT116 cells treated with Nutlin-3 (an inhibitor of mdm2 and p53 interaction) or DMSO control to study p53-regulated transcription |
1 | | FBXW7 | 'pituitary cancer' vs 'normal' | disease | Transcription profiling by array of human gonadotrope and null cell pituitary tumors |
1 | | FBXW7 | '100 microgram per milliliter trovafloxacin' vs 'none' | compound | Transcription profiling by array of human primary hepatocytes treated with trovafloxacin |
-1 | | FBXW7 | 'DMSO; prostate carcinoma' at '6 hour' vs 'DMSO; normal' at '6 hour' | compound, disease, time | Genome-wide transcriptome analysis of the dietary chemopreventive phytochemical sulforaphane on normal and prostate cancer cells. |
1 | | FBXW7 | '450 micromole per liter' vs '50 micromole per liter' in 'doxorubicin' at '1 day' | compound, sampling time point | Transcription profiling by array to investigate doxorubicin-induced toxicity in human cardiomyocytes derived from embryonic stem cell line SA121 |
-1 | | FBXW7 | 'chronic discoid lupus erythematosus' vs 'normal' | clinical history | Gene expression in cutaneous lupus erythematosus |
-1 | | FBXW7 | 'lapatinib and foretinib' vs 'DMSO' in 'acquired resistant to lapatinib' | compound, phenotype | BT474 and BT474-J4 microarray data |
-1 | | FBXW7 | 'Newcastle disease virus' at '16 hour' vs 'none' at '0 hour' | infect, time | Transcription profiling by array of human dendritic cells infected with Newcastle Disease Virus |
1 | | FBXW7 | 'transplant rejection; borderline' vs 'normal; none' in 'kidney transplant' | clinical information, disease, disease staging | Expression of the IL-17/Th17 axis in the development of acute renal allograft rejection |
1 | | FBXW7 | 'DICERER5/EX5; tunicamycin' vs 'DICERER5/EX5; control' | genotype, treatment | Induction of ER stress in HCT116 colon cancer cells |
