ENSG00000122728 (TAF1L)

homo sapiens

TATA-box binding protein associated factor 1 like

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Homo sapiens
Organism part
Showing 60 experiments:
image/svg+xml human body features 2009-05-27 Sjef text : Kevin (tsaitgaist) REDON http://commons.wikimedia.org/wiki/File:Human_body_features.svg cerebral cortex pleura brain heart breast thyroid gland adrenal gland lymph node bone marrow adipose tissue skeletal muscle leukocyte frontal cortex temporal lobe prefrontal cortex pituitary gland atrial appendage aorta coronary artery gastroesophageal junction left ventricle hippocampus hippocampus caecum ileum rectum nose tongue left atrium pulmonary valve mitral valve penis vas deferens seminal vesicle testis epididymis eye nasal septum oral cavity tonsil nasal pharynx lung spinal cord amygdala trachea throat bronchus tricuspid valve diaphragm liver stomach spleen duodenum gall bladder pancreas colon small intestine appendix smooth muscle urinary bladder prostate gland nerve cerebellum cerebellar hemisphere kidney renal cortex bone cartilage esophagus salivary gland parotid gland submandibular gland skin
Created with Highcharts 6.2.0adiposecervical vertebragallbladdermedulla oblongataprefrontal cortexspleenventricular septumaortabasal ganglionbreastdiencephalon and midbrainendometriumfallopian tubehindbrain without cerebellumlarge intestineleukocytemuscle layer of esophagusoccipital lobepenisrectumright renal pelvisskeletal muscle of trunktelencephalonthyroid glandtricuspid valve
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GTEX - organism part
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68 FANTOM5 project - adult
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32 Uhlen's Lab
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Hallstrom et al., 2014 - Organism part
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68 FANTOM5 project - fetal
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19 NIH Epigenomics Roadmap
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Illumina Body Map
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ENCODE (M. Snyder lab)
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HDBR developing brain - Carnegie Stage …
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Mammalian Kaessmann
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Zhu et al., 2018 - Organism part
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Human2021_Tissues - Wang et al. 2019
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Doll et al., 2017 - Organism part
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Human Proteome Map - adult
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McKetney et al., 2019 – organism part …
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Linscheid et al., 2020 – Tissues - …
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Human Proteome Map - fetus
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ovary, pancreas, liver, subst. nigra
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Proteomics
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Transcriptomics
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Kingdom
Species
Experiment type
Experimental variables
Regulation
Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
4.5199 × 10-2-6.5
TAF1L'ZEB1 knockout' vs 'wild type'genotypeAmpliseq transcriptomic array of REF seq. genes in ZEB1 knock out triple negative breast cancer cells
Adjusted p-valueLog2-fold change
1.4766 × 10-34.8
TAF1L'triple-negative breast cancer; breast carcinoma' vs 'normal'clinical information, diseaseRNA-seq of 17 breast tumor samples of three different subtypes and normal human breast organoids samples
Adjusted p-valueLog2-fold change
2.1259 × 10-23.6
TAF1L'sulforaphane; prostate carcinoma' at '24 hour' vs 'sulforaphane; normal' at '24 hour'compound, disease, timeGenome-wide transcriptome analysis of the dietary chemopreventive phytochemical sulforaphane on normal and prostate cancer cells.
Adjusted p-valueLog2-fold change
2.6253 × 10-203.5
TAF1L'501Mel; shBRG1 knockdown' vs '501Mel; control'cell line, phenotypeBRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq)
Adjusted p-valueLog2-fold change
4.9935 × 10-8-3.3
TAF1L'colorectal carcinoma' vs 'normal'block, diseaseRNA-seq of blood platelets from six tumor types and healthy donors
Adjusted p-valueLog2-fold change
1.0444 × 10-33.3
TAF1L'arsenite' vs 'control'compoundTranscription profiling by high throughput sequencing of 293S cells treated with arsenite
Adjusted p-valueLog2-fold change
2.8098 × 10-23.3
TAF1L'non-triple-negative breast cancer; breast carcinoma' vs 'normal'clinical information, diseaseRNA-seq of 17 breast tumor samples of three different subtypes and normal human breast organoids samples
Adjusted p-valueLog2-fold change
2.8229 × 10-33.1
TAF1L'induced into senescence; 5-aza-2-deoxycytidine' vs 'spontaneously immortal cells; control'phenotype, treatmentPathway Profiling of Replicative and Induced Senescence
Adjusted p-valueLog2-fold change
3.6712 × 10-23.1
TAF1L'DNMT1 homozygous knockout' vs 'wild type'phenotypeRNA-seq of human near-haploid cell line HAP1 with CRISPR-edited frameshift mutations
Adjusted p-valueLog2-fold change
2.8 × 10-22.8
TAF1L'small cell lung carcinoma' vs 'normal'diseaseRNA-seq of primary tumors from 79 small cell lung cancer patients and 7 normal lung tissue
Adjusted p-valueLog2-fold change
1.5444 × 10-4-2.7
TAF1L'pancreatic adenocarcinoma' vs 'normal'block, diseaseRNA-seq of blood platelets from six tumor types and healthy donors
Adjusted p-valueLog2-fold change
2.1018 × 10-5-2.6
TAF1L'breast carcinoma' vs 'normal'block, diseaseRNA-seq of blood platelets from six tumor types and healthy donors
Adjusted p-valueLog2-fold change
3.781 × 10-4-2.6
TAF1L'DMSO' in 'stimulated with interferon gamma and lipopolysaccharide' vs 'none' at '6 hour'compound, time, treatmentGPBAR1 agonism has a broad impact on blocking macrophage activation
Adjusted p-valueLog2-fold change
3.7348 × 10-2-2.6
TAF1L'EGR2-E356K' vs 'wild type genotype'genotypeRNA-sequencing of human B cells to investigate chronic lymphocytic leukemia mutations observed in hematopoietic multipotent progenitor fractions
Adjusted p-valueLog2-fold change
2.361 × 10-3-2.5
TAF1L'hepatobiliary carcinoma' vs 'normal'block, diseaseRNA-seq of blood platelets from six tumor types and healthy donors
Adjusted p-valueLog2-fold change
7.0935 × 10-92.4
TAF1L'osteosarcoma' vs 'normal'diseaseTranscription profiling by array of human bone specimens from patients with osteosarcoma
Adjusted p-valueLog2-fold change
1.6639 × 10-6-2.3
TAF1L'ulcerative colitis' vs 'normal'diseasePSC-IBD mucosal biology
Adjusted p-valueLog2-fold change
1.2236 × 10-92
TAF1L'blood alcohol content 0%' vs 'control' in 'time point 1'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
2.3909 × 10-82
TAF1L'blood alcohol content 0.02%declining' vs 'control' in 'time point 5'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
3.2481 × 10-3-2
TAF1L'EX00000246; stimulated with interferon gamma and lipopolysaccharide' vs 'none' at '6 hour'compound, time, treatmentGPBAR1 agonism has a broad impact on blocking macrophage activation
Adjusted p-valueLog2-fold change
2.2064 × 10-22
TAF1L'tumor tissue' vs 'non-malignant tissue'sampling siteRNA-seq of 199 non-small cell lung carcinoma patients and 19 paired normal lung tissues
Adjusted p-valueLog2-fold change
8.3199 × 10-81.9
TAF1L'blood alcohol content 0.04%declining' vs 'control' in 'time point 4'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
5.0255 × 10-4-1.9
TAF1L'EX00000246' vs 'none' in 'unstimulated' at '6 hour'compound, time, treatmentGPBAR1 agonism has a broad impact on blocking macrophage activation
Adjusted p-valueLog2-fold change
6.8772 × 10-61.8
TAF1L'medulloblastoma, large-cell' vs 'normal'diseasePediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes
Adjusted p-valueLog2-fold change
1.8517 × 10-71.7
TAF1L'blood alcohol content 0.04%rising' vs 'control' in 'time point 2'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
8.3029 × 10-81.6
TAF1L'blood alcohol content 0.08%' vs 'control' in 'time point 3'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
2.2502 × 10-21.6
TAF1L'embryonic stem cell differentiating toward definitive endoderm; 60 hour' vs 'embryonic stem cell; 0 hour'cell type, timeRNA-seq of definitive endoderm differentiation of human embryonic stem cells in early G1 phase of the cell cycle
Adjusted p-valueLog2-fold change
1.085 × 10-2-1.5
TAF1L'familial hemophagocytic lymphohistiocytosis 5' vs 'normal'diseaseRNAseq on PBMC of three patients with Familial Hemophagocytic Lymphohistiocytosis Type 5 (FHL5) and three age and sex-matched controls
Adjusted p-valueLog2-fold change
1.5542 × 10-51.4
TAF1L'differentiated; hAKPC-P' vs 're-differentiated; hIPod'cell type, phenotypeDifferentiation of human amniotic fluid kidney progenitor cells into podocytes and comparison with human conditionally immortalized podocytes
Adjusted p-valueLog2-fold change
9.3337 × 10-61.3
TAF1L'differentiated; hAKPC-P' vs 'undifferentiated; hIPod'cell type, phenotypeDifferentiation of human amniotic fluid kidney progenitor cells into podocytes and comparison with human conditionally immortalized podocytes
Adjusted p-valueLog2-fold change
3.0344 × 10-51.3
TAF1L'differentiated; hAKPC-P' vs 'undifferentiated; hAKPC-P'cell type, phenotypeDifferentiation of human amniotic fluid kidney progenitor cells into podocytes and comparison with human conditionally immortalized podocytes
Adjusted p-valueLog2-fold change
1.4782 × 10-31.3
TAF1L'Zaire ebolavirus lacking the mucin domain of GP' vs 'mock' at '8 hour'infect, timeHuman U937 cell transcriptome response to Zaire Ebola virus wild-type in the delta-”VP30 background and delta-mucin virus
Adjusted p-valueLog2-fold change
1.7316 × 10-21.3
TAF1L'7 hour' vs '0 hour' in 'MDA-LM2'cell line, timeTranscription profiling by high throughput sequencing in MDA-MB-231 and MDA-LM2 cell lines
Adjusted p-valueLog2-fold change
5.2455 × 10-41.2
TAF1L'glioblastoma' vs 'normal'diseasePediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes
Adjusted p-valueLog2-fold change
1.0887 × 10-31.2
TAF1L'atypical teratoid / rhabdoid tumor' vs 'normal'diseasePediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes
Adjusted p-valueLog2-fold change
1.5157 × 10-31.2
TAF1L'medulloblastoma' vs 'normal'diseasePediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes
Adjusted p-valueLog2-fold change
8.2267 × 10-3-1.1
TAF1L'suberoylanilide hydroxamic acid' vs 'control'compoundVascular histone deacetylation by pharmacological HDAC inhibition [SAHA, RNA-seq]
Adjusted p-valueLog2-fold change
4.5097 × 10-2-1.1
TAF1L'siRNAs against NELF' vs 'control' in 'whole-cell RNA'RNA, RNA interferenceIntegrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes [RNA-seq]
Adjusted p-valueLog2-fold change
5.5882 × 10-31
TAF1L'adult high grade glioma' vs 'normal'diseaseGene expression profile of pediatric and adult brain tumor types and normal brain
Adjusted p-valueLog2-fold change
1.1543 × 10-21
TAF1L'group 4 medulloblastoma' vs 'normal'diseaseGene expression profile of pediatric and adult brain tumor types and normal brain