ENSG00000124164 (VAPB)

homo sapiens

VAMP associated protein B and C

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Homo sapiens
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Showing 9 experiments:
image/svg+xml human body features 2009-05-27 Sjef text : Kevin (tsaitgaist) REDON http://commons.wikimedia.org/wiki/File:Human_body_features.svg cerebral cortex pleura brain heart breast thyroid gland adrenal gland lymph node bone marrow adipose tissue skeletal muscle leukocyte frontal cortex temporal lobe prefrontal cortex pituitary gland atrial appendage aorta coronary artery gastroesophageal junction left ventricle hippocampus hippocampus caecum ileum rectum nose tongue left atrium pulmonary valve mitral valve penis vas deferens seminal vesicle testis epididymis eye nasal septum oral cavity tonsil nasal pharynx lung spinal cord amygdala trachea throat bronchus tricuspid valve diaphragm liver stomach spleen duodenum gall bladder pancreas colon small intestine appendix smooth muscle urinary bladder prostate gland nerve cerebellum cerebellar hemisphere kidney renal cortex bone cartilage esophagus salivary gland parotid gland submandibular gland skin
Created with Highcharts 6.2.0adiposebraindorsal thalamusgall bladderlungovarysalivary glandtelencephalonvermiform appendixanimal ovaryatrium auricular regioncerebellar hemispherecolonendometriumfallopian tubehippocampal formationleft cardiac atriummiddle frontal gyrusnucleus accumbenspineal bodyprostate glandskinstomachtibial arteryurinary bladder
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GTEX - organism part
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32 Uhlen's Lab
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Mammalian Kaessmann
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Hallstrom et al., 2014 - Organism part
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Illumina Body Map
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HDBR developing brain - 14 post …
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HDBR developing brain - 10 post …
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ENCODE (M. Snyder lab)
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68 FANTOM5 project - adult
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Proteomics
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Transcriptomics
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.1125 × 10-7-2.5
VAPB'deferoxamine; 100 nanomolar echinomycin' vs 'deferoxamine; none'growth condition, treatmentTranscription profiling by array of human glioblastoma cells after stimulation with deferoxamine and treatment with polyamide 1, echinomycin, or HIF-1a siRNA
Adjusted p-valueLog2-fold change
2.6507 × 10-242
VAPB'P-bodies (cytosolic RNP granules)' vs 'pre-sorted fraction'fractionRNA-Seq of purified P-bodies from HEK293 cells
Adjusted p-valueLog2-fold change
1.508 × 10-461.9
ENSG00000124164'lipopolysaccharide' vs 'none' in 'systemic-onset juvenile idiopathic arthritis'disease, stimulusA multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis [RNA-Seq]
Adjusted p-valueLog2-fold change
7.3152 × 10-61.9
VAPB'ovarian cancer' vs 'normal' in 'stromal cell'cell type, diseaseA cancer associated fibroblasts (CAFs) specific gene signature in high grade serous ovarian cancer
Adjusted p-valueLog2-fold change
1.0324 × 10-2-1.9
VAPB'anti-m6A' vs 'none'treatmentTranscription profiling by high throughput sequencing in identification of m6A modified sequences in HepG2 cells
Adjusted p-valueLog2-fold change
5.1095 × 10-431.8
ENSG00000124164'lipopolysaccharide' vs 'none' in 'normal'disease, stimulusA multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis [RNA-Seq]
Adjusted p-valueLog2-fold change
5.004 × 10-8-1.8
VAPB'estrogen receptor alpha knockdown' vs 'control'phenotypeExpression data from MCF7 cell line after silencing of Estrogen receptor
Adjusted p-valueLog2-fold change
3.6231 × 10-841.7
VAPB'Digoxin; 400 nanomolar' vs 'DMSO'compoundExpression profiling of Jurkat cells infected with HIV-1 and treated with digoxin or DMSO
Adjusted p-valueLog2-fold change
2.6042 × 10-21.7
VAPB'HER2 Positive Breast Carcinoma; breast carcinoma' vs 'normal'clinical information, diseaseRNA-seq of 17 breast tumor samples of three different subtypes and normal human breast organoids samples
Adjusted p-valueLog2-fold change
1.1277 × 10-311.6
ENSG00000124164'Growth Medium' vs 'none' in 'systemic-onset juvenile idiopathic arthritis'disease, stimulusA multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis [RNA-Seq]
Adjusted p-valueLog2-fold change
6.6969 × 10-9-1.6
VAPB'blood alcohol content 0.02%declining' vs 'control' in 'time point 5'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
7.6911 × 10-8-1.6
VAPB'blood alcohol content 0.04%declining' vs 'control' in 'time point 4'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
4.1667 × 10-291.5
ENSG00000124164'Growth Medium' vs 'none' in 'normal'disease, stimulusA multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis [RNA-Seq]
Adjusted p-valueLog2-fold change
5.2453 × 10-8-1.5
VAPB'blood alcohol content 0.04%rising' vs 'control' in 'time point 2'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
5.9523 × 10-8-1.4
VAPB'blood alcohol content 0.08%' vs 'control' in 'time point 3'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
2.5429 × 10-5-1.4
VAPB'Alzheimers disease' vs 'normal' in 'posterior cingulate cortex'disease, organism partMicroarray analysis of six brain areas from Alzheimers disease patients and normal individuals
Adjusted p-valueLog2-fold change
3.317 × 10-5-1.4
VAPB'differentiated; hAKPC-P' vs 're-differentiated; hIPod'cell type, phenotypeDifferentiation of human amniotic fluid kidney progenitor cells into podocytes and comparison with human conditionally immortalized podocytes
Adjusted p-valueLog2-fold change
6.7641 × 10-17-1.3
VAPB'estrogen receptor alpha shRNA' vs 'scrambled shRNA'RNA interferenceRNA-seq of the human breast cancer ERα-suppressed MCF-7(MCF-7/SP10+) cells and of their internal control MCF-7 (MCF-7/C) cells
Adjusted p-valueLog2-fold change
1.5311 × 10-7-1.3
VAPB'blood alcohol content 0%' vs 'control' in 'time point 1'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
3.176 × 10-4-1.3
VAPB'Staphylococcus aureus strain 11490' at '6 hour' vs 'none' at '0 hour'time, treatmentTranscription profiling by array of human peripheral blood mononuclear cells after treatment with community-associated Staphylococcus aureus and incubation for different lengths of time
Adjusted p-valueLog2-fold change
3.1459 × 10-3-1.3
VAPB'teratozoospermia' vs 'normospermic'diseaseTranscription profiling by array of human sperm from normospermic and teratozoospermic individuals
Adjusted p-valueLog2-fold change
2.9892 × 10-6-1.2
VAPB'Alzheimers disease' vs 'normal' in 'middle temporal gyrus'disease, organism partMicroarray analysis of six brain areas from Alzheimers disease patients and normal individuals
Adjusted p-valueLog2-fold change
2.7175 × 10-5-1.2
VAPB'Snail overexpression' vs 'control'treatmentExpression data from breast cancer cell line MCF-7 with ectopic expression of the transcription factor Snail
Adjusted p-valueLog2-fold change
3.4684 × 10-5-1.2
VAPB'differentiated; hAKPC-P' vs 'undifferentiated; hIPod'cell type, phenotypeDifferentiation of human amniotic fluid kidney progenitor cells into podocytes and comparison with human conditionally immortalized podocytes
Adjusted p-valueLog2-fold change
5.7522 × 10-5-1.2
VAPB'Alzheimers disease' vs 'normal' in 'hippocampus'disease, organism partMicroarray analysis of six brain areas from Alzheimers disease patients and normal individuals
Adjusted p-valueLog2-fold change
1.1755 × 10-2-1.2
VAPB'herpes simplex virus G207' vs 'none'infectTranscription profiling by array of human malignant peripheral nerve sheath tumor cells after infection with herpes simplex virus G207
Adjusted p-valueLog2-fold change
1.0883 × 10-31.1
VAPB'T-helper 2 polarising' at '1 day' vs 'no stimulus'cell type, sampling time point, stimulusTranscription profiling by array of human CD4+T-cells, Th1/Th2 polarized time-series and primary memory subsets
Adjusted p-valueLog2-fold change
1.1775 × 10-31.1
VAPB'deferoxamine; none' vs 'control; none'growth condition, treatmentTranscription profiling by array of human glioblastoma cells after stimulation with deferoxamine and treatment with polyamide 1, echinomycin, or HIF-1a siRNA
Adjusted p-valueLog2-fold change
2.3018 × 10-10-1
VAPB'JQ1 (1 micromolar) and THZ1 (35 nanomolar)' vs 'none'compoundRNA-seq of IMR-5/75 neuroblastoma cell line treated with JQ1, THZ1 or combination against untreated controls
Adjusted p-valueLog2-fold change
5.0203 × 10-7-1
VAPB'miR-221/222' vs 'control'RNA interferenceGene expression profiling of MCF10A (miR-221/222 vs control)
Adjusted p-valueLog2-fold change
1.6028 × 10-4-1
VAPB'FGF8 100 nanogram per milliliter' vs 'none' in 'wild type genotype' at '20 day'genotype, stimulus, timeRNA-Seq of GNRH1 neurons differentiated from human pluripotent stem cells
Adjusted p-valueLog2-fold change
1.8826 × 10-4-1
VAPB'154; 1 micromolar' vs 'DMSO'compoundDevelopment of a small molecule for treatment of castration resistant prostate cancer via androgen receptor and IL6/STAT3 pathways
Adjusted p-valueLog2-fold change
1.9063 × 10-41
VAPB'MDAMB231; cocultured with fibroblast HFF1' vs 'MDAMB231; normal'cell line, growth conditionSystem-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity
Adjusted p-valueLog2-fold change
2.4173 × 10-41
VAPB'lung cancer' vs 'normal' in 'lung; Fresh-frozen tissue'disease, organism part, protocolTranscription profiling by array of formalin-fixed paraffin-embedded or fresh frozen human tumor samples
Adjusted p-valueLog2-fold change
4.9841 × 10-4-1
VAPB'medulloblastoma' vs 'normal'diseasePediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes
Adjusted p-valueLog2-fold change
6.1125 × 10-4-1
VAPB'Staphylococcus aureus strain 9897' at '6 hour' vs 'none' at '0 hour'time, treatmentTranscription profiling by array of human peripheral blood mononuclear cells after treatment with community-associated Staphylococcus aureus and incubation for different lengths of time
Adjusted p-valueLog2-fold change
8.736 × 10-4-1
VAPB'group 4 medulloblastoma' vs 'normal'diseaseGene expression profile of pediatric and adult brain tumor types and normal brain
Adjusted p-valueLog2-fold change
1.1326 × 10-3-1
VAPB'Staphylococcus aureus strain 10254' at '6 hour' vs 'none' at '0 hour'time, treatmentTranscription profiling by array of human peripheral blood mononuclear cells after treatment with community-associated Staphylococcus aureus and incubation for different lengths of time
Adjusted p-valueLog2-fold change
9.415 × 10-31
VAPB'non-triple-negative breast cancer; breast carcinoma' vs 'normal'clinical information, diseaseRNA-seq of 17 breast tumor samples of three different subtypes and normal human breast organoids samples
Adjusted p-valueLog2-fold change
1.1201 × 10-2-0.6
ENSG00000124164'papillary renal cell carcinoma' vs 'clear cell renal cell carcinoma'diseaseSWATH analysis of human kidney tissues to generate a digital map representing the proteome of biopsy level clinical samples.