ENSG00000125445 (MRPS7)

homo sapiens

mitochondrial ribosomal protein S7

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Homo sapiens
Organism part
Showing 69 experiments:
image/svg+xml human body features 2009-05-27 Sjef text : Kevin (tsaitgaist) REDON http://commons.wikimedia.org/wiki/File:Human_body_features.svg cerebral cortex pleura brain heart breast thyroid gland adrenal gland lymph node bone marrow adipose tissue skeletal muscle leukocyte frontal cortex temporal lobe prefrontal cortex pituitary gland atrial appendage aorta coronary artery gastroesophageal junction left ventricle hippocampus hippocampus caecum ileum rectum nose tongue left atrium pulmonary valve mitral valve penis vas deferens seminal vesicle testis epididymis eye nasal septum oral cavity tonsil nasal pharynx lung spinal cord amygdala trachea throat bronchus tricuspid valve diaphragm liver stomach spleen duodenum gall bladder pancreas colon small intestine appendix smooth muscle urinary bladder prostate gland nerve cerebellum cerebellar hemisphere kidney renal cortex bone cartilage esophagus salivary gland parotid gland submandibular gland skin
Created with Highcharts 6.2.0adiposediencephalon and midbrainkidneyparietal lobesmooth musclezone of skinaortabasal ganglionbreastcervical vertebraendocervixeyegall bladderhindbrain fragmentleft ventriclemammary glandmitral valvenucleus accumbensplateletpulmonary valveright atriumseminal vesiclesubmandibular glandThalamustongueuterine cervix
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GTEX - organism part
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68 FANTOM5 project - adult
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32 Uhlen's Lab
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Hallstrom et al., 2014 - Organism part
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19 NIH Epigenomics Roadmap
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Illumina Body Map
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ENCODE (M. Snyder lab)
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68 FANTOM5 project - fetal
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Mammalian Kaessmann
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Zhu et al., 2018 - Organism part
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Human2021_Tissues - Wang et al. 2019
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Human Proteome Map - adult
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Doll et al., 2017 - Organism part
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brain regions
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Human Proteome Map - fetus
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cerebellum and occipital lobe
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ovary, pancreas, liver, subst. nigra
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Kingdom
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Experiment type
Experimental variables
Regulation
Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.335 × 10-42.5
MRPS7'CD3 and CD28' vs 'none'compound, diseaseTranscription profiling by array of human CD3-positive T cells from patients with systemic lupus erythematosus
Adjusted p-valueLog2-fold change
1.6024 × 10-13-2.4
MRPS7'P-bodies (cytosolic RNP granules)' vs 'pre-sorted fraction'fractionRNA-Seq of purified P-bodies from HEK293 cells
Adjusted p-valueLog2-fold change
7.274 × 10-5-2.4
MRPS7'kidney transplant; transplant rejection; borderline' vs 'none; normal; none'clinical information, disease, disease stagingExpression of the IL-17/Th17 axis in the development of acute renal allograft rejection
Adjusted p-valueLog2-fold change
8.2139 × 10-15-2.3
MRPS7'systemic-onset juvenile idiopathic arthritis; placebo, Prednisone, non-steroidal anti-inflammatory drug, methotrexate' vs 'normal; none'disease, treatmentGene expression data of whole blood of systemic juvenile idiopathic arthritis (SJIA) patients treated with canakinumab or placebo and age matched healthy controls
Adjusted p-valueLog2-fold change
1.5622 × 10-42.2
MRPS7'T-helper 1 polarising' at '1 day' vs 'no stimulus'cell type, sampling time point, stimulusTranscription profiling by array of human CD4+T-cells, Th1/Th2 polarized time-series and primary memory subsets
Adjusted p-valueLog2-fold change
7.8921 × 10-4-2.2
MRPS7'transplant rejection; borderline' vs 'normal; none' in 'kidney transplant'clinical information, disease, disease stagingExpression of the IL-17/Th17 axis in the development of acute renal allograft rejection
Adjusted p-valueLog2-fold change
4.3032 × 10-832.1
MRPS7'Human gammaherpesvirus 4' at '2 day' vs 'none' at '0 day'infect, timeInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
Adjusted p-valueLog2-fold change
3.9658 × 10-782.1
MRPS7'Human gammaherpesvirus 4' at '3 day' vs 'none' at '0 day'infect, timeInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
Adjusted p-valueLog2-fold change
8.7381 × 10-23-2.1
MRPS7'tumor necrosis factor alpha' vs 'none' in 'brain microvascular endothelial cell; co-culture'cell type, growth condition, stimulusReactive astrocytes transduce blood-brain barrier inflammation through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin
Adjusted p-valueLog2-fold change
7.087 × 10-21-2
MRPS7'tumor necrosis factor alpha' vs 'none' in 'brain microvascular endothelial cell; monoculture'cell type, growth condition, stimulusReactive astrocytes transduce blood-brain barrier inflammation through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin
Adjusted p-valueLog2-fold change
1.2492 × 10-42
MRPS7'T-helper 2 polarising' at '1 day' vs 'no stimulus'cell type, sampling time point, stimulusTranscription profiling by array of human CD4+T-cells, Th1/Th2 polarized time-series and primary memory subsets
Adjusted p-valueLog2-fold change
7.1257 × 10-42
MRPS7'4-hydroxy-3-methyl-but-2-enyl pyrophosphate; 1 nanomolar' vs 'none'compoundTranscription profiling by array of human peripheral blood gamma-delta T cells stimulated with HMB-PP or OKT-3
Adjusted p-valueLog2-fold change
1.3768 × 10-2-2
MRPS7'Newcastle disease virus' at '14 hour' vs 'none' at '0 hour'infect, timeTranscription profiling by array of human dendritic cells infected with Newcastle Disease Virus
Adjusted p-valueLog2-fold change
5.8801 × 10-6-1.9
MRPS7'teratozoospermia' vs 'normospermic'diseaseTranscription profiling by array of human sperm from normospermic and teratozoospermic individuals
Adjusted p-valueLog2-fold change
1.7706 × 10-2-1.9
MRPS7'Newcastle disease virus' at '18 hour' vs 'none' at '0 hour'infect, timeTranscription profiling by array of human dendritic cells infected with Newcastle Disease Virus
Adjusted p-valueLog2-fold change
4.7879 × 10-21.9
MRPS7'interleukin-21 (Homo sapiens); 25 nanogram per milliliter' vs 'control; none'compound, growth conditionGene signature of CLL cells cultured with activated T cells or CD40L-expressing cells
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Log2-fold change
1.8
MRPS7'injected in NSG mouse' vs 'none' in 'none'stimulus, xenograftRNA-Seq of T cells sorted from human PBMCs, or from T cells stimulated with CD3/CD28 beads for 4 days, or from the spleen of NSG or NSG-HLA-A2/HHD mice, 7 days after transplantation with human PBMCs
Adjusted p-valueLog2-fold change
1.5658 × 10-2341.8
MRPS7'injected in NSG-HLA-A2/HHD mouse' vs 'none' in 'none'stimulus, xenograftRNA-Seq of T cells sorted from human PBMCs, or from T cells stimulated with CD3/CD28 beads for 4 days, or from the spleen of NSG or NSG-HLA-A2/HHD mice, 7 days after transplantation with human PBMCs
Adjusted p-valueLog2-fold change
2.663 × 10-391.8
MRPS7'Human gammaherpesvirus 4' at '4 day' vs 'none' at '0 day'infect, timeInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
Adjusted p-valueLog2-fold change
1.9943 × 10-5-1.8
MRPS7'kidney transplant; transplant rejection; acute' vs 'none; normal; none'clinical information, disease, disease stagingExpression of the IL-17/Th17 axis in the development of acute renal allograft rejection
Adjusted p-valueLog2-fold change
1.4322 × 10-31.8
MRPS7'anti-CD3 antibody; 1 microgram per milliliter' vs 'none'compoundTranscription profiling by array of human peripheral blood gamma-delta T cells stimulated with HMB-PP or OKT-3
Adjusted p-valueLog2-fold change
1.5495 × 10-31.8
MRPS7'cells p16-transfected' vs 'control'treatmentInduction of apoptotic processes in Capan-1 pancreatic carcinoma cells by restoration of p16INK4a expression
Adjusted p-valueLog2-fold change
1.8072 × 10-28-1.7
MRPS7'5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide; 0.4 millimolar' vs 'none'compoundTranscriptome of primary acute myeloid leukemia (AML) cells treated with AICAr
Adjusted p-valueLog2-fold change
4.7048 × 10-7-1.7
MRPS7'blood alcohol content 0.02%declining' vs 'control' in 'time point 5'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
2.2455 × 10-3-1.7
MRPS7'transplant rejection; acute' vs 'normal; none' in 'kidney transplant'clinical information, disease, disease stagingExpression of the IL-17/Th17 axis in the development of acute renal allograft rejection
Adjusted p-valueLog2-fold change
7.8828 × 10-3-1.7
MRPS7'gestational week 11 to 13' vs 'adult' in 'normal'developmental stage, phenotypeComparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents
Adjusted p-valueLog2-fold change
1.193 × 10-2-1.7
MRPS7'Newcastle disease virus' at '16 hour' vs 'none' at '0 hour'infect, timeTranscription profiling by array of human dendritic cells infected with Newcastle Disease Virus
Adjusted p-valueLog2-fold change
1.545 × 10-10-1.6
MRPS7'formalin-fixed,parafin-embedded xenograft; messageAmp Premier methodology' vs 'fresh-frozen xenograft; normal'infect, specimen with known storage state, treatmentA Methodology for Utilization of Predictive Genomic Signatures in FFPE Samples
Adjusted p-valueLog2-fold change
1.88 × 10-71.6
MRPS7'stimulation' vs 'control'growth conditionEffect of human breast tumor supernatant on normal CD4+ T cells (Confirmation Set SN)
Adjusted p-valueLog2-fold change
2.442 × 10-5-1.6
MRPS7'7 day' vs '3 day' in 'hypoxia'environmental stress, timeTranscription profiling by array of the effect of hypoxia in tumour-initiating cells derived from a colorectal cancer patient
Adjusted p-valueLog2-fold change
3.4457 × 10-5-1.6
MRPS7'herpes simplex virus G207' vs 'none'infectTranscription profiling by array of human malignant peripheral nerve sheath tumor cells after infection with herpes simplex virus G207
Adjusted p-valueLog2-fold change
4.0324 × 10-41.6
MRPS7'lung cancer' vs 'normal' in 'lung; Fresh-frozen tissue'disease, organism part, protocolTranscription profiling by array of formalin-fixed paraffin-embedded or fresh frozen human tumor samples
Adjusted p-valueLog2-fold change
6.234 × 10-3-1.6
MRPS7'Francisella tularensis novicida' vs 'uninfected'infectTranscription profiling by array of human peripheral blood mononuclear cells infected with Francisella tularensis
Adjusted p-valueLog2-fold change
9.7854 × 10-3-1.6
MRPS7'arsenite' vs 'control'compoundTranscription profiling by high throughput sequencing of 293S cells treated with arsenite
Adjusted p-valueLog2-fold change
1.3715 × 10-331.5
MRPS7'cisplatin; 100 micromolar' vs 'none' in 'scrambled siRNA'RNA interference, compoundRNA-seq of human head and neck cancer cell line SQD9 knock-out for TMEM45A exposed to cisplatin
Adjusted p-valueLog2-fold change
1.3604 × 10-171.5
MRPS7'Human gammaherpesvirus 4' at '1 day' vs 'none' at '0 day'infect, timeInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
Adjusted p-valueLog2-fold change
3.7384 × 10-17-1.5
MRPS7'poly(I:C); 25 microgram per milliliter' vs 'none' in 'none; none'compound, infect, stimulusRNA-seq of H1N1 infected monocyte-derived dendritic cells (MoDC), stimulated with single-stranded oligonucleotides (ssON) and/or Poly I:C.
Adjusted p-valueLog2-fold change
7.117 × 10-11-1.5
MRPS7'CRISPR-Cas9 induced GNRH1 reporter; 27 day' vs 'wild type genotype; 20 day'genotype, stimulus, timeRNA-Seq of GNRH1 neurons differentiated from human pluripotent stem cells
Adjusted p-valueLog2-fold change
1.1575 × 10-81.5
MRPS7'squamous cell carcinoma' vs 'normal'block, diseaseRNA-seq of a panel of non-melanoma skin cancer lesions
Adjusted p-valueLog2-fold change
3.05 × 10-7-1.5
MRPS7'blood alcohol content 0.08%' vs 'control' in 'time point 3'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
1.8792 × 10-6-1.5
MRPS7'SKR6LR cells resistant to lapanitib' vs 'SKR6 cells with elevated HER2 expression'phenotypeNuclear factor kappa B activation-induced anti-apoptosis renders HER2 positive cells drug resistant and accelerates tumor growth
Adjusted p-valueLog2-fold change
2.0281 × 10-61.5
MRPS7'actinic keratosis' vs 'normal'block, diseaseRNA-seq of a panel of non-melanoma skin cancer lesions
Adjusted p-valueLog2-fold change
2.5362 × 10-5-1.5
MRPS7'hypoxia' vs 'normoxia' at '7 day'environmental stress, timeTranscription profiling by array of the effect of hypoxia in tumour-initiating cells derived from a colorectal cancer patient
Adjusted p-valueLog2-fold change
2.4818 × 10-41.5
MRPS7'differentiated macrophage' at '168 hour' vs '0 hour'timeTranscription profiling of human monocytes to macrophage differentiation
Adjusted p-valueLog2-fold change
4.0468 × 10-41.5
MRPS7'ovarian cancer' vs 'normal' in 'stromal cell'cell type, diseaseA cancer associated fibroblasts (CAFs) specific gene signature in high grade serous ovarian cancer
Adjusted p-valueLog2-fold change
1.6644 × 10-2-1.5
MRPS7'Newcastle disease virus' at '12 hour' vs 'none' at '0 hour'infect, timeTranscription profiling by array of human dendritic cells infected with Newcastle Disease Virus
Adjusted p-valueLog2-fold change
1.3905 × 10-361.4
MRPS7'cisplatin; 100 micromolar' vs 'none' in 'TMEM45A knockdown by siRNA'RNA interference, compoundRNA-seq of human head and neck cancer cell line SQD9 knock-out for TMEM45A exposed to cisplatin
Adjusted p-valueLog2-fold change
1.9989 × 10-231.4
MRPS7'KLF17 overexpression' at '24 day' vs 'wild type' at '0 day'phenotype, timeRNA-seq of hESCs undergoing primed to naive-like resetting via exogenous KLF17 overexpression
Adjusted p-valueLog2-fold change
3.4009 × 10-231.4
MRPS7'KLF17 overexpression' at '5 day' vs 'wild type' at '0 day'phenotype, timeRNA-seq of hESCs undergoing primed to naive-like resetting via exogenous KLF17 overexpression
Adjusted p-valueLog2-fold change
2.9954 × 10-6-1.4
MRPS7'blood alcohol content 0.04%declining' vs 'control' in 'time point 4'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
3.0977 × 10-61.4
MRPS7'MCF-7 clone 5C' vs 'MCF-7'cell lineTranscription profiling by array of human hormone-responsive MCF-7 cells versus estrogen-deprived breast cancer cells
Adjusted p-valueLog2-fold change
4.4415 × 10-6-1.4
MRPS7'blood alcohol content 0%' vs 'control' in 'time point 1'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
7.0147 × 10-6-1.4
MRPS7'GLV-1h153' at '24 hour' vs 'control'infect, timeExpression data from human pancreatic cells PANC-1 infected with oncolytic vaccinia virus GLV-1h153
Adjusted p-valueLog2-fold change
1.1155 × 10-31.4
MRPS7'T-helper 1 polarising' at '5 days' vs 'no stimulus'cell type, sampling time point, stimulusTranscription profiling by array of human CD4+T-cells, Th1/Th2 polarized time-series and primary memory subsets
Adjusted p-valueLog2-fold change
2.3592 × 10-31.4
MRPS7'3 h DRB 8 min 4sU' vs 'untreated'treatment4sUDRB-seq: measuring transcription elongation and initiation genomewide
Adjusted p-valueLog2-fold change
1.1095 × 10-21.4
MRPS7'non-triple-negative breast cancer; breast carcinoma' vs 'normal'clinical information, diseaseRNA-seq of 17 breast tumor samples of three different subtypes and normal human breast organoids samples
Adjusted p-valueLog2-fold change
1.2185 × 10-2-1.4
MRPS7'freshly isolated' vs 'monolayer'growth conditionTranscription profiling by array of human mesenchymal stem cells in 2D culture compared with two different alginate-based 3D scaffolds
Adjusted p-valueLog2-fold change
2.1662 × 10-2-1.4
MRPS7'Newcastle disease virus' at '10 hour' vs 'none' at '0 hour'infect, timeTranscription profiling by array of human dendritic cells infected with Newcastle Disease Virus
Adjusted p-valueLog2-fold change
2.7334 × 10-21.4
MRPS7'non primary Sjogren syndrome sicca' vs 'normal'block, diseaseTranscription profiling by array of parotid tissue from Primary Sjögren’s Syndrome and controls
Adjusted p-valueLog2-fold change
1.1358 × 10-113-1.3
MRPS7'501Mel; shBRG1 knockdown' vs '501Mel; control'cell line, phenotypeBRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq)
Adjusted p-valueLog2-fold change
5.808 × 10-191.3
MRPS7'KLF17 overexpression' vs 'wild type' at '5 day'phenotype, timeRNA-seq of hESCs undergoing primed to naive-like resetting via exogenous KLF17 overexpression
Adjusted p-valueLog2-fold change
1.8077 × 10-61.3
MRPS7'sebaceous of Jadassohn nevus' vs 'normal'block, diseaseRNA-seq of a panel of non-melanoma skin cancer lesions
Adjusted p-valueLog2-fold change
4.6393 × 10-6-1.3
MRPS7'ochratoxin A; 130 nanomolar' vs 'none' at '1 day'compound, timeMicroarray mRNA data of RPTEC/TERT1 cells exposed to nephrotoxic chemicals ochratoxin A and potassium bromate
Adjusted p-valueLog2-fold change
2.3435 × 10-5-1.3
MRPS7'blood alcohol content 0.04%rising' vs 'control' in 'time point 2'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
4.6737 × 10-5-1.3
MRPS7'lipid; 10 volume percent' vs 'control'compoundComparison of a macrophage like cell line derived from THP-1 cells
Adjusted p-valueLog2-fold change
3.1462 × 10-4-1.3
MRPS7'Francisella tularensis Schu S4' vs 'uninfected'infectTranscription profiling by array of human peripheral blood mononuclear cells infected with Francisella tularensis
Adjusted p-valueLog2-fold change
8.2905 × 10-4-1.3
MRPS7"after autologous stem cell transplantation" vs "before autologous stem cell transplantation"timeRNA-seq of human multiple myeloma patients myeloid-derived suppressor cells (M-MDSC)
Adjusted p-valueLog2-fold change
1.9167 × 10-3-1.3
MRPS7'wild type; BREFELDIN A' vs 'wild type; control'genotype, treatmentInduction of ER stress in HCT116 colon cancer cells
Adjusted p-valueLog2-fold change
2.3555 × 10-21.3
MRPS7'cocultured with CD40L- cells' vs 'control' in 'none'compound, growth conditionGene signature of CLL cells cultured with activated T cells or CD40L-expressing cells
Adjusted p-valueLog2-fold change
3.6876 × 10-21.3
MRPS7'RXF 393; poorly differentiated hypernephroma; P10' vs 'RXF 393; poorly differentiated hypernephroma; P0'cell line, disease, passageMicroarray analysis of xenograft models in use at the Developmental Therapeutics Program of the National Cancer Institute (DTP-NCI)
Adjusted p-valueLog2-fold change
5.0329 × 10-25-1.2
MRPS7'11 day' vs '0 day'timeRNA-Seq characterization of human H1-derived NPC differentiation timecourse
Adjusted p-valueLog2-fold change
1.0411 × 10-121.2
MRPS7'Influenza A virus (A/California/07-00001/2009(H1N1))' vs 'none' in 'poly(I:C); 25 microgram per milliliter; none'compound, infect, stimulusRNA-seq of H1N1 infected monocyte-derived dendritic cells (MoDC), stimulated with single-stranded oligonucleotides (ssON) and/or Poly I:C.
Adjusted p-valueLog2-fold change
4.8528 × 10-9-1.2
MRPS7'breast carcinoma' vs 'normal'block, diseaseRNA-seq of blood platelets from six tumor types and healthy donors
Adjusted p-valueLog2-fold change
1.1925 × 10-4-1.2
MRPS7'PLX4720; 1 micromolar' vs 'none'compoundRNA-seq of the human melanoma cell-line A375P treated with the BRAF inhibitor PLX4720 and a DMSO control
Adjusted p-valueLog2-fold change
2.258 × 10-41.2
MRPS7'astrocyte overexpressing 4 genes' vs 'astrocyte'phenotypeTranscription profiling by array of human primary astrocytes, cancer stem cells derived from astrocytes overexpressing various oncogenic and iPSC-inducing factors, glioma stem cells and gliblastomat cell line to compare their expression profiles and tumor-initiating capabilities
Adjusted p-valueLog2-fold change
2.4521 × 10-41.2
MRPS7'NKAES-derived NK cells' vs 'primary human NK cells' in 'none'clinical history, compoundTranscription profiling by array of human natural killer cells
Adjusted p-valueLog2-fold change
2.0965 × 10-32-1.1
MRPS7'CCNK knock-down' vs 'mock'RNA interferenceRNA-seq analysis of vorinostat-resistant HCT116 cells following gene knockdown of potential vorinostat-resistance candidate genes
Adjusted p-valueLog2-fold change
7.892 × 10-15-1.1
MRPS7'suberoylanilide hydroxamic acid' vs 'control'compoundVascular histone deacetylation by pharmacological HDAC inhibition [SAHA, RNA-seq]
Adjusted p-valueLog2-fold change
3.6681 × 10-131.1
MRPS7'Human gammaherpesvirus 4' at '14 day' vs 'none' at '0 day'infect, timeInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
Adjusted p-valueLog2-fold change
1.9203 × 10-9-1.1
MRPS7'ssON; 0.5 micromolar' vs 'none' in 'none; none'compound, infect, stimulusRNA-seq of H1N1 infected monocyte-derived dendritic cells (MoDC), stimulated with single-stranded oligonucleotides (ssON) and/or Poly I:C.
Adjusted p-valueLog2-fold change
1.862 × 10-8-1.1
MRPS7'miR-221/222' vs 'control'RNA interferenceGene expression profiling of MCF10A (miR-221/222 vs control)
Adjusted p-valueLog2-fold change
8.3115 × 10-81.1
MRPS7'tongue squamous cell carcinoma' vs 'normal' in 'vehicle'compound, diseaseTranscription profiling by high throughput sequencing of retinoic acid treated human oral squamous cell carcinoma cells and normal cells
Adjusted p-valueLog2-fold change
2.8355 × 10-61.1
MRPS7'12 hour' vs '0 hour' in 'MCF-10A-H1047R'cell line, timeKnock-in of PIK3CA-H1047R into MCF-10A
Adjusted p-valueLog2-fold change
3.6105 × 10-6-1.1
MRPS7'shEED' vs 'control'RNA interferenceRNA-seq transcriptional profiling in primary human erythroid progenitor cells upon shRNA-mediated knockdown of PRC2 core subunits
Adjusted p-valueLog2-fold change
6.8041 × 10-61.1
MRPS7'Human gammaherpesvirus 4' at '5 day' vs 'none' at '0 day'infect, timeInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
Adjusted p-valueLog2-fold change
1.1972 × 10-5-1.1
MRPS7'T-cell mediated transplant rejection' vs 'normal'diseaseIntragraft anti-viral-specific gene expression as a distinctive transcriptional signature for polyomavirus-associated nephropathy
Adjusted p-valueLog2-fold change
1.6635 × 10-5-1.1
MRPS7'non-small cell lung carcinoma' vs 'normal'block, diseaseRNA-seq of blood platelets from six tumor types and healthy donors
Adjusted p-valueLog2-fold change
1.9131 × 10-5-1.1
MRPS7'fibroblast; Klinefelter’s Syndrome' vs 'embryonic stem cell; control'cell type, diseaseExpression data of the iPSCs derived from foreskin fibroblast cells of normal person and KS patient
Adjusted p-valueLog2-fold change
3.7125 × 10-5-1.1
MRPS7'colorectal carcinoma' vs 'normal'block, diseaseRNA-seq of blood platelets from six tumor types and healthy donors
Adjusted p-valueLog2-fold change
9.6875 × 10-5-1.1
MRPS7'systemic-onset juvenile idiopathic arthritis; Prednisone, non-steroidal anti-inflammatory drug, methotrexate' vs 'normal; none'disease, treatmentGene expression data of whole blood of systemic juvenile idiopathic arthritis (SJIA) patients treated with canakinumab or placebo and age matched healthy controls
Adjusted p-valueLog2-fold change
1.3154 × 10-41.1
MRPS7'breast cancer; breast' vs 'normal; breast'disease, organism partGene expression profiling of triple negative breast cancer, normal ductal cells, and normal tissues
Adjusted p-valueLog2-fold change
2.1287 × 10-41.1
MRPS7'Human gammaherpesvirus 4' at '8 day' vs 'none' at '0 day'infect, timeInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
Adjusted p-valueLog2-fold change
4.0414 × 10-4-1.1
MRPS7'highly invasive' vs 'poorly invasive'phenotypeExpression data from CL1-0 and CL1-5 lung cancer cell line.
Adjusted p-valueLog2-fold change
4.9555 × 10-41.1
MRPS7'low dose IL2' vs 'none' in 'primary human NK cells'clinical history, compoundTranscription profiling by array of human natural killer cells
Adjusted p-valueLog2-fold change
7.6191 × 10-41.1
MRPS7'differentiating monocyte' at '16 hour' vs '0 hour'timeTranscription profiling of human monocytes to macrophage differentiation
Adjusted p-valueLog2-fold change
1.1359 × 10-31.1
MRPS7'astrocyte overexpressing 7 genes' vs 'astrocyte'phenotypeTranscription profiling by array of human primary astrocytes, cancer stem cells derived from astrocytes overexpressing various oncogenic and iPSC-inducing factors, glioma stem cells and gliblastomat cell line to compare their expression profiles and tumor-initiating capabilities
Adjusted p-valueLog2-fold change
1.0199 × 10-2-1.1
MRPS7'hepatocellular carcinoma, neoplasm' vs 'normal; normal tissue' in 'liver'disease, organism partTranscription profiling by array of normal pancreas, primary pancreatic ductal adenocarcinoma (PDAC), normal liver, and pancreatic liver metastases using the Affymetrix HG-U133A array
Adjusted p-valueLog2-fold change
1.3138 × 10-21.1
MRPS7'cultured skin substitute; 3 day' vs 'skin; 0 day'organism part, timeTranscription profiling by array of human grafted engineered skin substitutes
Adjusted p-valueLog2-fold change
3.1345 × 10-21.1
MRPS7'Epstein-Barr virus infection' vs 'none' in 'palatine tonsil'infect, organism partTranscription profiling by array of B cells from tonsils, cord blood and peripheral blood infected with Epstein-Barr virus
Adjusted p-valueLog2-fold change
2.6725 × 10-621
MRPS7'expression of estrogen receptor beta fused to C terminus tandem affinity purification tag' vs 'expression of estrogen receptor alpha fused to C terminus tandem affinity purification tag'genotypeThe nuclear receptor ERbeta engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading. Part 4
Adjusted p-valueLog2-fold change
4.7133 × 10-40-1
MRPS7'progenitor cell of endocrine pancreas' vs 'definitive endoderm cell' in 'GATA6 R456C/+; Patient A"cell line, cell type, genotype, individualRNA-seq of definitive endoderm and pancreatic progenitor cells derived in vitro from human pluripotent stem cells in order to study the role of transcription factor GATA6 in human pancreas development
Adjusted p-valueLog2-fold change
7.1275 × 10-25-1
MRPS7'1 day' vs '0 day'timeRNA-Seq characterization of human H1-derived NPC differentiation timecourse
Adjusted p-valueLog2-fold change
2.5487 × 10-191
MRPS7'induced pluripotent stem cell' vs 'fibroblast of dermis' in 'Klinefelter's syndrome'cell type, diseaseKlinefelter syndrome derived hiPSCs show similar XCI behavior as female hPSCs
Adjusted p-valueLog2-fold change
1.5762 × 10-14-1
MRPS7'lapatinib; 500 nanomolar; 7 day' vs 'dimethyl sulfoxide; 1 day'compound, timeRNA-seq of human oesophageal adenocarcinoma OE19 cell line treated with lapatinib
Adjusted p-valueLog2-fold change
2.4654 × 10-10-1
MRPS7'stimulated with interferon gamma and lipopolysaccharide' vs 'unstimulated' in 'EX00000246' at '24 hour'compound, time, treatmentGPBAR1 agonism has a broad impact on blocking macrophage activation
Adjusted p-valueLog2-fold change
1.7253 × 10-61
MRPS7'24 hour' vs '0 hour' in 'MCF-10A-H1047R'cell line, timeKnock-in of PIK3CA-H1047R into MCF-10A
Adjusted p-valueLog2-fold change
2.1085 × 10-6-1
MRPS7'EPZ6438; 10x lowest cytotoxic concentration' vs 'DMSO' in 'SUDHL6' at '6 day'cell line, compound, timeExpression data from EZH2 inhibitor treated Non-Hodgkins Lymphoma cell lines
Adjusted p-valueLog2-fold change
8.9735 × 10-61
MRPS7'SR; poorly differentiated B cell origin leukemia; P10' vs 'SR; poorly differentiated B cell origin leukemia; P0'cell line, disease, passageMicroarray analysis of xenograft models in use at the Developmental Therapeutics Program of the National Cancer Institute (DTP-NCI)
Adjusted p-valueLog2-fold change
1.2753 × 10-5-1
MRPS7'trichostatin A; 500 nanomolar' vs 'control'compoundTranscription profiling by high throughput sequencing of human aortic endothelial cell treated with TSA
Adjusted p-valueLog2-fold change
1.3394 × 10-51
MRPS7'deferoxamine; 100 nanomolar echinomycin' vs 'deferoxamine; none'growth condition, treatmentTranscription profiling by array of human glioblastoma cells after stimulation with deferoxamine and treatment with polyamide 1, echinomycin, or HIF-1a siRNA
Adjusted p-valueLog2-fold change
1.7627 × 10-5-1
MRPS7'deprived of Lysine' vs 'control media' in 'MCF7' at '24 hour'cell line, growth condition, timeTranscription profiling by array of human MCF-7 and PC3 cells grown under amino acid deprived or rich conditions for 24 or 48 hours
Adjusted p-valueLog2-fold change
2.2916 × 10-5-1
MRPS7'EPZ6438; 10x lowest cytotoxic concentration' vs 'DMSO' in 'KARPAS_422' at '6 day'cell line, compound, timeExpression data from EZH2 inhibitor treated Non-Hodgkins Lymphoma cell lines
Adjusted p-valueLog2-fold change
9.2537 × 10-51
MRPS7'atopic eczema; normal skin' vs 'normal; normal skin'clinical information, disease, phenotypeTranscription profiling by array of acute and chronic atopic dermatitis compared to normal skin
Adjusted p-valueLog2-fold change
1.238 × 10-4-1
MRPS7'human metapneumovirus' at '48 hour' vs 'none' at '48 hour'infect, timeTranscription profiling by array of human bronchiole epithelial cells infected with human metapneumovirus
Adjusted p-valueLog2-fold change
2.6763 × 10-41
MRPS7'erythroleukemia; ZRSR2 shRNA' vs 'normal'disease, genotypeRNA-seq of bone marrow from patients with myelodysplastic syndrome
Adjusted p-valueLog2-fold change
3.4665 × 10-4-1
MRPS7'human metapneumovirus' at '72 hour' vs 'none' at '48 hour'infect, timeTranscription profiling by array of human bronchiole epithelial cells infected with human metapneumovirus
Adjusted p-valueLog2-fold change
3.7622 × 10-4-1
MRPS7'Alzheimers disease' vs 'normal' in 'hippocampus'disease, organism partMicroarray analysis of six brain areas from Alzheimers disease patients and normal individuals
Adjusted p-valueLog2-fold change
6.8336 × 10-41
MRPS7'astrocyte overexpressing 4 genes' vs 'glioblastoma cell line'phenotypeTranscription profiling by array of human primary astrocytes, cancer stem cells derived from astrocytes overexpressing various oncogenic and iPSC-inducing factors, glioma stem cells and gliblastomat cell line to compare their expression profiles and tumor-initiating capabilities
Adjusted p-valueLog2-fold change
1.0323 × 10-3-1
MRPS7'PMA' vs 'vehicle' in 'ZXDC1 knockdown'compound, genotypeExpression data from knockdown of ZXDC1/2 in PMA-treated U937
Adjusted p-valueLog2-fold change
2.1368 × 10-3-1
MRPS7'aging cells' vs 'spontaneously immortal cells; control'phenotype, treatmentPathway Profiling of Replicative and Induced Senescence
Adjusted p-valueLog2-fold change
4.4427 × 10-3-1
MRPS7'TGFbeta3' vs 'control' at '3 day'growth condition, timeTranscription profiling by array of human bone marrow mesenchymal stem cells after treatment with BMP2 or TGFbeta-3
Adjusted p-valueLog2-fold change
1.1964 × 10-21
MRPS7'lesional' vs 'non-lesional' in 'one-cycle cDNA synthesis from bulk tissue'phenotype, protocolCombined Use of Laser Capture Microdissection and Microarray Analysis Identifies Locally Expressed Disease-Related Genes in Focal Regions of Psoriasis Vulgaris Skin Lesions
Adjusted p-valueLog2-fold change
1.2702 × 10-2-1
MRPS7'chronic obstructive pulmonary disease' vs 'normal' in 'Streptococcus pneumoniae CGSP14'disease, infectTranscriptional profiling of primary human alveolar macrophages challenged with Streptococcus pneumoniae from patients with chronic obstructive pulmonary disease compared to healthy donors
Adjusted p-valueLog2-fold change
1.3731 × 10-21
MRPS7'Streptococcus pneumoniae CGSP14' vs 'none' in 'normal'disease, infectTranscriptional profiling of primary human alveolar macrophages challenged with Streptococcus pneumoniae from patients with chronic obstructive pulmonary disease compared to healthy donors
Adjusted p-valueLog2-fold change
3.9001 × 10-2-1
MRPS7'1 micromolar NSC319726' vs 'none'compoundTranscription profiling by array of ovarian carcinoma TOV-112D cells treated with NSC319726 to investigate the effect on p53 targets