6.5 | | GUCY2D | 'dexamethasone; 1 micromolar' vs 'vehicle' | compound | RNA-seq in GR18 cell line to identify genes regulated by the Glucocorticoid Receptor (24h treatment) |
4.1 | | GUCY2D | 'induced pluripotent stem cell' vs 'fibroblast of dermis' in 'normal' | cell type, disease | Klinefelter syndrome derived hiPSCs show similar XCI behavior as female hPSCs |
-4 | | GUCY2D | 'colorectal carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
-3.8 | | GUCY2D | 'GATA6 R456C/+; Patient A' vs 'wild type genotype; H9' in 'definitive endoderm cell' | cell line, cell type, genotype, individual | RNA-seq of definitive endoderm and pancreatic progenitor cells derived in vitro from human pluripotent stem cells in order to study the role of transcription factor GATA6 in human pancreas development |
-3.6 | | ENSG00000132518 | 'Growth Medium' vs 'none' in 'normal' | disease, stimulus | A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis [RNA-Seq] |
-3.5 | | GUCY2D | 'breast carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
3.4 | | GUCY2D | 'tongue squamous cell carcinoma' vs 'normal' in 'vehicle' | compound, disease | Transcription profiling by high throughput sequencing of retinoic acid treated human oral squamous cell carcinoma cells and normal cells |
3.2 | | GUCY2D | '24 hour' vs '0 hour' in 'MCF-10A-H1047R' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
-3 | | GUCY2D | 'pancreatic adenocarcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
-2.7 | | ENSG00000132518 | 'Growth Medium' vs 'none' in 'systemic-onset juvenile idiopathic arthritis' | disease, stimulus | A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis [RNA-Seq] |
-2.7 | | GUCY2D | 'untreated; air-liquid interface (day 14)' vs 'untreated; submerged (day 8)' | compound, growth condition | Genome-wide expression profiling of an in vitro model for studying esophageal epithelial differentiation |
-2.5 | | GUCY2D | 'interleukin 13; 100 nanogram per milliliter; air-liquid interface (day 14)' vs 'untreated; submerged (day 8)' | compound, growth condition | Genome-wide expression profiling of an in vitro model for studying esophageal epithelial differentiation |
-2.4 | | GUCY2D | 'visceral Leishmaniasis; active infection' vs 'normal' | disease, disease staging | RNA-seq of blood samples from patients diagnosed with visceral leishmaniasis and asymptomatic individuals (Brazil) |
-2.4 | | GUCY2D | 'GATA6 R456C/+; Patient A' vs 'wild type genotype; H9' in 'progenitor cell of endocrine pancreas' | cell line, cell type, genotype, individual | RNA-seq of definitive endoderm and pancreatic progenitor cells derived in vitro from human pluripotent stem cells in order to study the role of transcription factor GATA6 in human pancreas development |
2.3 | | GUCY2D | 'shEED' vs 'control' | RNA interference | RNA-seq transcriptional profiling in primary human erythroid progenitor cells upon shRNA-mediated knockdown of PRC2 core subunits |
-2.3 | | GUCY2D | 'Barrett’s esophagus; non-dysplastic' vs 'normal' | disease, disease staging | Whole transcriptome profiling of Esophageal adenocarcinoma and Barrett's |
-2.2 | | GUCY2D | 'esophageal adenocarcinoma' vs 'normal' | disease, disease staging | Whole transcriptome profiling of Esophageal adenocarcinoma and Barrett's |
2.1 | | GUCY2D | 'squamous cell carcinoma' vs 'normal' | block, disease | RNA-seq of a panel of non-melanoma skin cancer lesions |
2.1 | | GUCY2D | 'lapatinib; 500 nanomolar; 1 day' vs 'dimethyl sulfoxide; 1 day' | compound, time | RNA-seq of human oesophageal adenocarcinoma OE19 cell line treated with lapatinib |
2.1 | | GUCY2D | 'neoplasm' vs 'normal tissue adjacent to neoplasm' | sampling site | Next Generation Sequencing Identification of HBV-MLL4 integration and its molecular basis in Chinese hepatocellular carcinoma |
-2 | | ENSG00000132518 | 'lipopolysaccharide' vs 'none' in 'systemic-onset juvenile idiopathic arthritis' | disease, stimulus | A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis [RNA-Seq] |
2 | | GUCY2D | 'triple-negative breast cancer; breast carcinoma' vs 'normal' | clinical information, disease | RNA-seq of 17 breast tumor samples of three different subtypes and normal human breast organoids samples |
-2 | | GUCY2D | 'Barrett’s esophagus; low-grade dysplasia' vs 'normal' | disease, disease staging | Whole transcriptome profiling of Esophageal adenocarcinoma and Barrett's |
1.9 | | GUCY2D | 'progenitor cell of endocrine pancreas' vs 'definitive endoderm cell' in 'GATA6 R456C/+; Patient A" | cell line, cell type, genotype, individual | RNA-seq of definitive endoderm and pancreatic progenitor cells derived in vitro from human pluripotent stem cells in order to study the role of transcription factor GATA6 in human pancreas development |
1.8 | | GUCY2D | '6 hour' vs '0 hour' in 'MCF-10A' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
1.8 | | GUCY2D | 'actinic keratosis' vs 'normal' | block, disease | RNA-seq of a panel of non-melanoma skin cancer lesions |
1.7 | | GUCY2D | 'HES1 homozygous knockout' vs 'wild type genotype' | genotype | RNA-seq of Human Embryonic Stem Cell derived pancreas progenitor differentiation, Day 13 of wildtype, HES1-/-, NEUROG3-/- and HES1-/-NEUROG3-/- genotypes |
-1.7 | | GUCY2D | 'hepatobiliary carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
1.7 | | GUCY2D | 'sebaceous of Jadassohn nevus' vs 'normal' | block, disease | RNA-seq of a panel of non-melanoma skin cancer lesions |
-1.6 | | GUCY2D | 'embryonic stem cell differentiating toward definitive endoderm; 36 hour' vs 'embryonic stem cell; 0 hour' | cell type, time | RNA-seq of definitive endoderm differentiation of human embryonic stem cells in early G1 phase of the cell cycle |
1.5 | | GUCY2D | 'differentiated; hAKPC-P' vs 'undifferentiated; hIPod' | cell type, phenotype | Differentiation of human amniotic fluid kidney progenitor cells into podocytes and comparison with human conditionally immortalized podocytes |
-1.5 | | GUCY2D | 'non-small cell lung carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
-1.5 | | GUCY2D | 'embryonic stem cell differentiating toward definitive endoderm; 24 hour' vs 'embryonic stem cell; 0 hour' | cell type, time | RNA-seq of definitive endoderm differentiation of human embryonic stem cells in early G1 phase of the cell cycle |
-1.5 | | GUCY2D | 'familial hemophagocytic lymphohistiocytosis 5' vs 'normal' | disease | RNAseq on PBMC of three patients with Familial Hemophagocytic Lymphohistiocytosis Type 5 (FHL5) and three age and sex-matched controls |
1.4 | | ENSG00000132518 | 'ulcerative colitis' vs 'normal' | disease | RNA-seq of 134 patients undergoing bowel resection for inflammatory bowel disease and controls |
1.4 | | GUCY2D | 'differentiated; hAKPC-P' vs 're-differentiated; hIPod' | cell type, phenotype | Differentiation of human amniotic fluid kidney progenitor cells into podocytes and comparison with human conditionally immortalized podocytes |
1.4 | | GUCY2D | 'shEZH2' vs 'control' | RNA interference | RNA-seq transcriptional profiling in primary human erythroid progenitor cells upon shRNA-mediated knockdown of PRC2 core subunits |
1.3 | | GUCY2D | 'SA181; hepatocyte-like cell' vs 'SA181; embryonic stem cell' | block, cell line, cell type, fraction | Gene expression profile of human embryonic stem cell-derived hepatocyte-like cells |
1.3 | | GUCY2D | 'ChiPS4; hepatocyte-like cell' vs 'ChiPS4; induced pluripotent stem cell' | block, cell line, cell type, fraction | Gene expression profile of human embryonic stem cell-derived hepatocyte-like cells |
1.3 | | GUCY2D | 'overexpression of Halo-RelA' vs 'control' | phenotype | Transcription profiling by high throughput sequencing of HEK293 cells expressing Halo-RelA, Halo-NFkB1, or Halo tag alone |
-1.3 | | GUCY2D | 'embryonic stem cell differentiating toward definitive endoderm; 60 hour' vs 'embryonic stem cell; 0 hour' | cell type, time | RNA-seq of definitive endoderm differentiation of human embryonic stem cells in early G1 phase of the cell cycle |
1.2 | | GUCY2D | 'differentiated; hAKPC-P' vs 'undifferentiated; hAKPC-P' | cell type, phenotype | Differentiation of human amniotic fluid kidney progenitor cells into podocytes and comparison with human conditionally immortalized podocytes |
1.1 | | GUCY2D | 'DGAT2 homozygous knockout' vs 'wild type genotype' in 'fatty acids (800 micromolar) and fructose (5.5 millimolar)' | genotype, treatment | Investigating NAFLD from RNA-seq data (human cell line Huh7) for samples under three treatments: low fat low sugar, low fat high sugar and high fat high sugar. Wild type samples are compared against DGAT2 knocked out. |
-1.1 | | GUCY2D | 'JQ1 (250 micromolar); ICG-001 (2.5 micromolar)' vs 'dimethyl sulfoxide' | stimulus | RNA-seq in HSJD-DIPG-007 cells treated with JQ1, ICG-001, JQ1 and ICG-001 and DMSO as control. |
-1.1 | | GUCY2D | 'embryonic stem cell differentiating toward definitive endoderm; 12 hour' vs 'embryonic stem cell; 0 hour' | cell type, time | RNA-seq of definitive endoderm differentiation of human embryonic stem cells in early G1 phase of the cell cycle |
-1.1 | | GUCY2D | 'definitive endoderm cell; 72 hour' vs 'embryonic stem cell; 0 hour' | cell type, time | RNA-seq of definitive endoderm differentiation of human embryonic stem cells in early G1 phase of the cell cycle |
1 | | GUCY2D | 'phorbol 13-acetate 12-myristate; 100 nanomolar' at '3 day' vs 'none' at '0 day' in 'none' | compound, stimulus, time | Transcriptional profiling of THP1-derived human macrophages with different stimuli |
1 | | ENSG00000132518 | 'Crohn's disease' vs 'normal' | disease | RNA-seq of 134 patients undergoing bowel resection for inflammatory bowel disease and controls |
-1 | | GUCY2D | 'wild type; BREFELDIN A' vs 'wild type; control' | genotype, treatment | Induction of ER stress in HCT116 colon cancer cells |
