ENSG00000185652 (NTF3)

homo sapiens

neurotrophin 3

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Homo sapiens
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Showing 33 experiments:
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.1643 × 10-46
NTF3'human cytomegalovirus (Towne strain)' vs 'none'infectRNAseq of proneural glioblastoma stem-like cells 72 hours after infection with human cytomegalovirus (CMV) Towne strain
Adjusted p-valueLog2-fold change
1.444 × 10-8-5.4
NTF3'HER2 Positive Breast Carcinoma; breast carcinoma' vs 'normal'clinical information, diseaseRNA-seq of 17 breast tumor samples of three different subtypes and normal human breast organoids samples
Adjusted p-valueLog2-fold change
6.4308 × 10-7-5.4
NTF3'liver tumor' vs 'adjacent non-tumor tissue'clinical informationTranscriptome sequencing of human hepatocellular carcinoma
Adjusted p-valueLog2-fold change
5.942 × 10-54.9
NTF3'astrocyte overexpressing 7 genes' vs 'glioblastoma cell line'phenotypeTranscription profiling by array of human primary astrocytes, cancer stem cells derived from astrocytes overexpressing various oncogenic and iPSC-inducing factors, glioma stem cells and gliblastomat cell line to compare their expression profiles and tumor-initiating capabilities
Adjusted p-valueLog2-fold change
4.6375 × 10-154-4.8
NTF3'SOX2 overexpression' vs 'wild type' in 'U-2982'cell line, phenotypeRNA-seq of human glioblastoma cell lines with overexpression of SOX2, SFRP2
Adjusted p-valueLog2-fold change
5.0399 × 10-434.6
NTF3'doxycycline; 0.5 microgram per milliliter; Day 1 post Neurogenin induction' vs 'control'compound, treatmentRapid neurogenesis through transcriptional activation in human stem cell (RNA-Seq)
Adjusted p-valueLog2-fold change
5.0222 × 10-8-4.3
NTF3'tumor' vs 'paratumoral tissue'clinical informationTranscriptomic characterization of Hepatocellular Carcinoma with CTNNB1 mutation
Adjusted p-valueLog2-fold change
6.6786 × 10-10-4.2
NTF3'tumor necrosis factor alpha' vs 'none' in 'brain microvascular endothelial cell; co-culture'cell type, growth condition, stimulusReactive astrocytes transduce blood-brain barrier inflammation through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin
Adjusted p-valueLog2-fold change
3.1818 × 10-10-4.1
NTF3'non-triple-negative breast cancer; breast carcinoma' vs 'normal'clinical information, diseaseRNA-seq of 17 breast tumor samples of three different subtypes and normal human breast organoids samples
Adjusted p-valueLog2-fold change
1.9936 × 10-184
NTF3'aging cells' vs 'spontaneously immortal cells; control'phenotype, treatmentPathway Profiling of Replicative and Induced Senescence
Adjusted p-valueLog2-fold change
8.8061 × 10-6-3.9
NTF3'CRISPR-Cas9 induced GNRH1 reporter; 27 day' vs 'wild type genotype; 20 day'genotype, stimulus, timeRNA-Seq of GNRH1 neurons differentiated from human pluripotent stem cells
Adjusted p-valueLog2-fold change
9.129 × 10-63.9
NTF3'astrocyte overexpressing 7 genes' vs 'astrocyte'phenotypeTranscription profiling by array of human primary astrocytes, cancer stem cells derived from astrocytes overexpressing various oncogenic and iPSC-inducing factors, glioma stem cells and gliblastomat cell line to compare their expression profiles and tumor-initiating capabilities
Adjusted p-valueLog2-fold change
8.0837 × 10-253.7
NTF3'young cells' vs 'spontaneously immortal cells; control'phenotype, treatmentPathway Profiling of Replicative and Induced Senescence
Adjusted p-valueLog2-fold change
8.059 × 10-4-3.7
NTF3'P0 cells' vs 'untreated P4 cells'passage, treatmentTranscription profiling by high throughput sequencing of human fetal differentiated P0 retinal pigment epithelial cells, mesenchymal P4 cells, and A-83-01 rescued P4 cells
Adjusted p-valueLog2-fold change
2.0902 × 10-7-3.5
NTF3'breast carcinoma' vs 'normal'block, diseaseRNA-seq of blood platelets from six tumor types and healthy donors
Adjusted p-valueLog2-fold change
2.4559 × 10-16-3.2
NTF3'neoplasm' vs 'normal tissue adjacent to neoplasm'sampling siteMassive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma
Adjusted p-valueLog2-fold change
3.3858 × 10-343.1
NTF3'dexamethasone; 1 micromolar' vs 'ethanol'compoundRNA-seq in GR18 cell line to identify genes regulated by the Glucocorticoid Receptor
Adjusted p-valueLog2-fold change
2.3859 × 10-113.1
NTF3'doxycycline; 0.5 microgram per milliliter; Day 3 post Neurogenin induction' vs 'control'compound, treatmentRapid neurogenesis through transcriptional activation in human stem cell (RNA-Seq)
Adjusted p-valueLog2-fold change
1.8402 × 10-73.1
NTF3'ochratoxin A; 130 nanomolar' vs 'none' at '1 day'compound, timeMicroarray mRNA data of RPTEC/TERT1 cells exposed to nephrotoxic chemicals ochratoxin A and potassium bromate
Adjusted p-valueLog2-fold change
7.7585 × 10-53
NTF3'group 3 medulloblastoma' vs 'normal'diseaseGene expression profile of pediatric and adult brain tumor types and normal brain
Adjusted p-valueLog2-fold change
1.6328 × 10-4-3
NTF3'KLF17 overexpression' at '24 day' vs 'wild type' at '0 day'phenotype, timeRNA-seq of hESCs undergoing primed to naive-like resetting via exogenous KLF17 overexpression
Adjusted p-valueLog2-fold change
5.5584 × 10-6-2.9
NTF3'FiPS generated with GATA3VP16, SOX2vP16, KLF4 and cMYC' vs 'Control fibroblasts'cell typeGene expression from human fibroblasts
Adjusted p-valueLog2-fold change
1.2365 × 10-52.9
NTF3'transduced with HOXA1' vs 'control'treatmentGene expression profiling of enforced HOXA1 expression in melanoma cell line
Adjusted p-valueLog2-fold change
3.9771 × 10-7-2.7
NTF3'SNCA overexpression' vs 'wild type genotype'genotypeRNA-seq of human midbrain organoid models of Parkinson's Disease
Adjusted p-valueLog2-fold change
6.4449 × 10-3-2.6
NTF3'neoplasm' vs 'normal tissue adjacent to neoplasm'sampling siteNext Generation Sequencing Identification of HBV-MLL4 integration and its molecular basis in Chinese hepatocellular carcinoma
Adjusted p-valueLog2-fold change
1.2798 × 10-22.6
NTF3'astrocyte overexpressing 4 genes' vs 'glioblastoma cell line'phenotypeTranscription profiling by array of human primary astrocytes, cancer stem cells derived from astrocytes overexpressing various oncogenic and iPSC-inducing factors, glioma stem cells and gliblastomat cell line to compare their expression profiles and tumor-initiating capabilities
Adjusted p-valueLog2-fold change
2.5869 × 10-26-2.5
NTF3'wild type ZFP36L1; 4-hydroxytamoxifen; senescent cell' vs 'wild type non-senescent cell'compound, genotype, phenotypeAnalysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant
Adjusted p-valueLog2-fold change
1.3043 × 10-72.5
NTF3'SOX2 siRNA' vs 'negative control' in '2102Ep'RNA interference, cell lineGene expression data from SOX2 knock-out 2102Ep and NTera-2 human embryonal carcinoma cell lines
Adjusted p-valueLog2-fold change
9.3595 × 10-92.4
NTF3'replicatively senescent; grown until growth arrest' vs 'spontaneously immortal cells; control'phenotype, treatmentPathway Profiling of Replicative and Induced Senescence
Adjusted p-valueLog2-fold change
1.6204 × 10-24-2.3
NTF3'wild type; 4-hydroxytamoxifen; senescent cell' vs 'wild type non-senescent cell'compound, genotype, phenotypeAnalysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant
Adjusted p-valueLog2-fold change
2.4819 × 10-5-2.3
NTF3'7 hour' vs '0 hour' in 'MDA-LM2'cell line, timeTranscription profiling by high throughput sequencing in MDA-MB-231 and MDA-LM2 cell lines
Adjusted p-valueLog2-fold change
2.1169 × 10-3-2.3
NTF3'24 hours with hMSC Adipogenic Differentiation Bullet Kit' vs 'none' in 'polysome'fraction, protocolRNA-seq of total RNA from human adipose tissue stem cells induced to adipogenesis and osteogenesis for 24 hours
Adjusted p-valueLog2-fold change
1.0033 × 10-3-2.2
NTF3'KLF17 overexpression' at '1 day' vs 'wild type' at '0 day'phenotype, timeRNA-seq of hESCs undergoing primed to naive-like resetting via exogenous KLF17 overexpression
Adjusted p-valueLog2-fold change
1.1886 × 10-3-2.2
NTF3'colorectal carcinoma' vs 'normal'block, diseaseRNA-seq of blood platelets from six tumor types and healthy donors
Adjusted p-valueLog2-fold change
3.4076 × 10-142.1
NTF3'GATA6 R456C/+; Patient A' vs 'wild type genotype; H9' in 'definitive endoderm cell'cell line, cell type, genotype, individualRNA-seq of definitive endoderm and pancreatic progenitor cells derived in vitro from human pluripotent stem cells in order to study the role of transcription factor GATA6 in human pancreas development
Adjusted p-valueLog2-fold change
8.6476 × 10-13-2.1
NTF3'pBABE-puro-H-RasG12V; senescent' vs 'control; proliferative'genotype, phenotypeTranscription profiling by high throughput sequencing of proliferative and Ras-induced senescent human primary fibroblasts
Adjusted p-valueLog2-fold change
8.9033 × 10-8-2.1
NTF3'4-hydroxytamoxifen' vs 'none' in 'scrambled control'RNA interference, compoundTranscription profiling of human cells transfected with a miR-34a LNA inhibitor to investigate its role in oncogene-induced senescence
Adjusted p-valueLog2-fold change
1.3935 × 10-38-2
NTF3'shRNA knockdown of PROX1' vs 'wild type phenotype' in 'U-343_MGa'cell line, phenotypeRNA-seq analysis of PROX1 overexpression and knockdown in glioblastoma cell lines
Adjusted p-valueLog2-fold change
5.5856 × 10-52
NTF3'group 4 medulloblastoma' vs 'normal'diseaseGene expression profile of pediatric and adult brain tumor types and normal brain
Adjusted p-valueLog2-fold change
8.5907 × 10-3-2
NTF3'triple-negative breast cancer; breast carcinoma' vs 'normal'clinical information, diseaseRNA-seq of 17 breast tumor samples of three different subtypes and normal human breast organoids samples
Adjusted p-valueLog2-fold change
6.4884 × 10-8-1.9
NTF3'inflammatory breast cancer' vs 'normal'diseaseExpression Analysis of Microdissected Inflammatory Breast Cancer
Adjusted p-valueLog2-fold change
1.6444 × 10-6-1.9
NTF3'Braf activated' vs 'untreated'treatmentExpression data from Control, Uninfected and BRAF infected cells
Adjusted p-valueLog2-fold change
8.8933 × 10-5-1.9
NTF3'induced pluripotent stem cell' vs 'fibroblast of dermis' in 'normal'cell type, diseaseKlinefelter syndrome derived hiPSCs show similar XCI behavior as female hPSCs
Adjusted p-valueLog2-fold change
2.0585 × 10-7-1.8
NTF3'4-hydroxytamoxifen' vs 'none' in 'miR-34a LNA inhibitor'RNA interference, compoundTranscription profiling of human cells transfected with a miR-34a LNA inhibitor to investigate its role in oncogene-induced senescence
Adjusted p-valueLog2-fold change
2.7887 × 10-71.8
NTF3'154; 1 micromolar' vs 'DMSO'compoundDevelopment of a small molecule for treatment of castration resistant prostate cancer via androgen receptor and IL6/STAT3 pathways
Adjusted p-valueLog2-fold change
3.0897 × 10-6-1.8
NTF3'non-inflammatory breast cancer' vs 'normal'diseaseExpression Analysis of Microdissected Inflammatory Breast Cancer
Adjusted p-valueLog2-fold change
1.6889 × 10-5-1.8
NTF3'10 unit per milliliter; JFHA' vs 'control'compoundPrimary human hepatocytes treated with IL28B and the HCV JFH1 Genotype 2A clone.
Adjusted p-valueLog2-fold change
2.3396 × 10-5-1.8
NTF3'Down syndrome' vs 'normal'diseaseRNA-seq of induced pluripotent stem cells from monozygotic twins discordant for trisomy 21
Adjusted p-valueLog2-fold change
9.62 × 10-3-1.8
NTF3'tumor necrosis factor alpha' vs 'none' in 'brain microvascular endothelial cell; monoculture'cell type, growth condition, stimulusReactive astrocytes transduce blood-brain barrier inflammation through a TNFα-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin
Adjusted p-valueLog2-fold change
3.9136 × 10-21.8
NTF3'NSAID-exacerbated respiratory disease' vs 'normal'diseaseTotal RNAseq of human healthy control inferior turbinate and glucocorticoid-treated, NSAID-exacerbated respiratory disease (N-ERD) nasal polyp nasal brushings
Adjusted p-valueLog2-fold change
6.7847 × 10-111.7
NTF3'3 to 5 weeks post ovulation' vs 'adult' in 'normal'developmental stage, diseaseComparison of gene expression profiling of human lung at four developmental stages and lung adenocarcioma
Adjusted p-valueLog2-fold change
1.2812 × 10-61.7
NTF3'Numb5 overexpression' vs 'control' in 'MDAMB231'cell line, genotypeExpression profile of MDA-MB-231 and MCF7 cells stably transfected with GFP-Numb4, GFP-Numb5, GFP-Numb6
Adjusted p-valueLog2-fold change
2.4889 × 10-61.7
NTF3'CLF1' vs 'CLS1; co-culture with CAF to generate sphere'cell line, growth condition, passageCancer-Associated Fibroblasts Support Lung Cancer Stemness through Paracrine IGF-II/IGF1R/Nanog Signaling
Adjusted p-valueLog2-fold change
3.8069 × 10-5-1.7
NTF3'gefitinib; 24 hour' vs 'none; 2 hour'compound, timeRNA-seq of A431 cell line after gefitinib treatment
Adjusted p-valueLog2-fold change
5.2181 × 10-31.7
NTF3'valproic acid; 15 millimolar' vs 'control' at '3 day'compound, sampling time pointRNA-seq of Primary Human Hepatocytes (PHH) exposed to Valproic Acid (VPA) for 3 days daily and 3 days daily exposure followed by 3 days washout.
Adjusted p-valueLog2-fold change
1.1911 × 10-21.7
NTF3'post full confluence' vs 'early cell adhesion'sampling time pointTranscription profiling by array of human osteogenic cells at different stages of the differentiation process
Adjusted p-valueLog2-fold change
3.8439 × 10-21.7
NTF3'astrocyte overexpressing 4 genes' vs 'astrocyte'phenotypeTranscription profiling by array of human primary astrocytes, cancer stem cells derived from astrocytes overexpressing various oncogenic and iPSC-inducing factors, glioma stem cells and gliblastomat cell line to compare their expression profiles and tumor-initiating capabilities
Adjusted p-valueLog2-fold change
1.4141 × 10-7-1.6
NTF3'11 day' vs '0 day'timeRNA-Seq characterization of human H1-derived NPC differentiation timecourse
Adjusted p-valueLog2-fold change
4.4774 × 10-71.6
NTF3'AD80; 0.05 micromolar' vs 'vehicle' in 'HuH-7'cell line, compoundRNA-seq of human hepatocellular carcinoma cell line Huh7 and immortalized hepatocyte cell line THLE5B treated with experimental compound AD80, Sorafenib, and vehicle for 24 hours
Adjusted p-valueLog2-fold change
4.6865 × 10-71.6
NTF3'Numb6 overexpression' vs 'control' in 'MDAMB231'cell line, genotypeExpression profile of MDA-MB-231 and MCF7 cells stably transfected with GFP-Numb4, GFP-Numb5, GFP-Numb6
Adjusted p-valueLog2-fold change
3.2414 × 10-51.6
NTF3'5 day' vs '0 day'timeGlobal expression profiling time series of early human embryonic stem cell differentiation towards the mesoderm lineage
Adjusted p-valueLog2-fold change
1.3506 × 10-41.6
NTF3'medulloblastoma' vs 'normal'diseaseExpression data from human brain tumors and human normal brain
Adjusted p-valueLog2-fold change
3.1975 × 10-21.6
NTF3'sodium metavanadate' vs 'control'compoundSodium metavanadate exhibits carcinogenic tendencies in vitro in immortalized human bronchial epithelial cells [DEG.C]
Adjusted p-valueLog2-fold change
8.1822 × 10-81.5
NTF3'blood alcohol content 0.04%rising' vs 'control' in 'time point 2'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
9.5057 × 10-7-1.5
NTF3'heat shock' vs 'untreated'growth conditionRNA-seq analysis of U2OS cells exposed to heat stress
Adjusted p-valueLog2-fold change
7.6676 × 10-51.5
NTF3'6 day' vs '0 day'timeGlobal expression profiling time series of early human embryonic stem cell differentiation towards the mesoderm lineage
Adjusted p-valueLog2-fold change
2.6579 × 10-4-1.5
NTF3'BT20; 24 hour' vs 'BT20; 0 hour'cell line, timeTranscription profiling by array of triple-negative, HER2-overexpressing and hormone-sensitive breast carcinoma cell lines after EGFR inhibition with erlotinib
Adjusted p-valueLog2-fold change
5.477 × 10-41.5
NTF3'astrocyte overexpressing 7 genes' vs 'glioma stem cell line'phenotypeTranscription profiling by array of human primary astrocytes, cancer stem cells derived from astrocytes overexpressing various oncogenic and iPSC-inducing factors, glioma stem cells and gliblastomat cell line to compare their expression profiles and tumor-initiating capabilities
Adjusted p-valueLog2-fold change
3.6799 × 10-31.5
NTF3'Ataxia-telangiectasia' vs 'normal' in 'neural stem cell'cell type, diseaseHuman iPSC-Derived Cerebellar Neurons from a Patient with Ataxia-Telangiectasia Reveal Disrupted Gene Regulatory Networks
Adjusted p-valueLog2-fold change
5.1999 × 10-31.5
NTF3'KLF17 overexpression' at '5 day' vs 'wild type' at '0 day'phenotype, timeRNA-seq of hESCs undergoing primed to naive-like resetting via exogenous KLF17 overexpression
Adjusted p-valueLog2-fold change
3.4093 × 10-71.4
NTF3'blood alcohol content 0.02%declining' vs 'control' in 'time point 5'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
6.4976 × 10-6-1.4
NTF3'embryonic stem cell differentiating toward definitive endoderm; 36 hour' vs 'embryonic stem cell; 0 hour'cell type, timeRNA-seq of definitive endoderm differentiation of human embryonic stem cells in early G1 phase of the cell cycle
Adjusted p-valueLog2-fold change
7.4087 × 10-6-1.4
NTF3'Braf activated' vs 'empty vector'treatmentExpression data from Control, Uninfected and BRAF infected cells
Adjusted p-valueLog2-fold change
2.614 × 10-31.4
NTF3'7 day' vs '0 day'timeGlobal expression profiling time series of early human embryonic stem cell differentiation towards the mesoderm lineage
Adjusted p-valueLog2-fold change
3.2472 × 10-31.4
NTF3'medulloblastoma' vs 'normal'diseasePediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes
Adjusted p-valueLog2-fold change
2.0182 × 10-2-1.4
NTF3'RXF 393; poorly differentiated hypernephroma; P10' vs 'RXF 393; poorly differentiated hypernephroma; P0'cell line, disease, passageMicroarray analysis of xenograft models in use at the Developmental Therapeutics Program of the National Cancer Institute (DTP-NCI)
Adjusted p-valueLog2-fold change
3.6226 × 10-21.4
NTF3'breast cancer' vs 'normal'diseaseHeterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast
Adjusted p-valueLog2-fold change
3.873 × 10-42-1.3
NTF3'psoriasis; lesional skin' vs 'normal; normal'disease, phenotypeTranscriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms
Adjusted p-valueLog2-fold change
1.3665 × 10-71.3
NTF3'blood alcohol content 0%' vs 'control' in 'time point 1'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
7.2691 × 10-61.3
NTF3'HNF4a homozygous deletion mutant (DBD Mut)' vs 'wild type'genetic modificationTranscriptomic profiling of mutant and WT HNF4alpha hepatic progenitor stage cells
Adjusted p-valueLog2-fold change
2.2729 × 10-5-1.3
NTF3'2 micromolar retinoic acid' vs 'none'compoundTranscription profiling by array of human embryonic stem cells response to retinoic acid exposure
Adjusted p-valueLog2-fold change
8.9417 × 10-4-1.3
NTF3'MCT8[P321L]' vs 'correction to MCT8[wt]' in 'derived brain microvascular endothelial cell'cell type, compound, genotypeRNA-seq analysis of MCT8-deficient and healthy control brain microvascular endothelial cells (BMECs) and neural cells
Adjusted p-valueLog2-fold change
2.3697 × 10-31.3
NTF3'9 day' vs '0 day'timeGlobal expression profiling time series of early human embryonic stem cell differentiation towards the mesoderm lineage
Adjusted p-valueLog2-fold change
8.0682 × 10-31.3
NTF3'sonic hedgehog group medulloblastoma' vs 'normal'diseaseGene expression profile of pediatric and adult brain tumor types and normal brain
Adjusted p-valueLog2-fold change
1.2719 × 10-2-1.3
NTF3'induced pluripotent stem cell' vs 'fibroblast of dermis' in 'Klinefelter's syndrome'cell type, diseaseKlinefelter syndrome derived hiPSCs show similar XCI behavior as female hPSCs
Adjusted p-valueLog2-fold change
4.8273 × 10-10-1.2
NTF3'progenitor cell of endocrine pancreas' vs 'definitive endoderm cell' in 'GATA6 R456C/+; Patient A"cell line, cell type, genotype, individualRNA-seq of definitive endoderm and pancreatic progenitor cells derived in vitro from human pluripotent stem cells in order to study the role of transcription factor GATA6 in human pancreas development
Adjusted p-valueLog2-fold change
6.9752 × 10-71.2
NTF3'blood alcohol content 0.08%' vs 'control' in 'time point 3'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
1.2224 × 10-61.2
NTF3'blood alcohol content 0.04%declining' vs 'control' in 'time point 4'sampling time point, treatmentMicroarray characterization of gene expression changes in blood during acute ethanol exposure
Adjusted p-valueLog2-fold change
2.7429 × 10-51.2
NTF3'recombinant human MFAP5 protein' vs 'vehicle control'compoundExpression analysis on microfibrillar associated protein 5 (MFAP5) protein treated ovarian cancer cell line OVCA432
Adjusted p-valueLog2-fold change
1.3535 × 10-4-1.2
NTF3'2 micromolar; retinoic acid' vs '1 micromolar DMSO'compoundTranscription profiling by array of human embryonic stem cells response to retinoic acid exposure
Adjusted p-valueLog2-fold change
1.5176 × 10-41.2
NTF3'4 day' vs '0 day'timeGlobal expression profiling time series of early human embryonic stem cell differentiation towards the mesoderm lineage
Adjusted p-valueLog2-fold change
2.0614 × 10-4-1.2
NTF3'paediatric' vs 'foetal' in 'epithelial cell of large intestine'cell type, developmental stageTranscriptional profiling by array of intestinal epithelial cells from foetal and paediatric gut
Adjusted p-valueLog2-fold change
1.7664 × 10-31.2
NTF3'Human betacoronavirus 2c England-Qatar/2012; 24 hour' vs 'mock; 18 hour'infect, timeTranscription profiling of human bronchial epithelial cell line Calu-3 2B4 infected with Human Coronavirus MERS-CoV-London
Adjusted p-valueLog2-fold change
2.2468 × 10-31.2
NTF3'ovarian cancer' vs 'normal' in 'epithelial cell'cell type, diseaseA cancer associated fibroblasts (CAFs) specific gene signature in high grade serous ovarian cancer
Adjusted p-valueLog2-fold change
4.9559 × 10-3-1.2
NTF3'expression of wild type RBM47' vs 'empty vector'genotypeIdentification of alternatively spliced transcripts in brain metastatic derivatives of MDA-MB-231 breast cancer cells in response to RBM47 expression
Adjusted p-valueLog2-fold change
5.4326 × 10-31.2
NTF3'Neurobasal medium' vs 'DMEM/F12 with glutamax'growth conditionRNA sequencing of human iPSC-derived brain microvascular endothelial cells.
Adjusted p-valueLog2-fold change
9.4031 × 10-3-1.2
NTF3'high guluronic acid alginate' vs 'monolayer'growth conditionTranscription profiling by array of human mesenchymal stem cells in 2D culture compared with two different alginate-based 3D scaffolds
Adjusted p-valueLog2-fold change
2.8762 × 10-10-1.1
NTF3'lesion' vs 'normal tissue adjacent to lesion' in '1 week'sampling site, timeRNA-sequencing of the mRNA transcriptome in lesional and non-lesional skin, across three time-points in severe psoriasis patients treated with the tumor necrosis factor (TNF) inhibitor, etanercept
Adjusted p-valueLog2-fold change
1.8296 × 10-91.1
NTF3'6 to 8 weeks post ovulation' vs 'adult' in 'normal'developmental stage, diseaseComparison of gene expression profiling of human lung at four developmental stages and lung adenocarcioma
Adjusted p-valueLog2-fold change
4.6606 × 10-71.1
NTF3'DISC1 exon 2 mut/mut' vs 'wild type' in 'neural progenitor cell' at 'embryoid body, day 17'cell type, genotype, sampling time pointTranscriptome profiling of human neural progenitor cells and neurons with DISC1 interruption
Adjusted p-valueLog2-fold change
2.1651 × 10-5-1.1
NTF3'papillary renal cell carcinoma' vs 'normal' in 'adult'developmental stage, diseaseGene expression data from human data of different types of renal tumors and normal kidneys
Adjusted p-valueLog2-fold change
7.0776 × 10-5-1.1
NTF3'GATA6 R456C/+; Patient A' vs 'wild type genotype; H9' in 'progenitor cell of endocrine pancreas'cell line, cell type, genotype, individualRNA-seq of definitive endoderm and pancreatic progenitor cells derived in vitro from human pluripotent stem cells in order to study the role of transcription factor GATA6 in human pancreas development
Adjusted p-valueLog2-fold change
1.6375 × 10-4-1.1
NTF3'tuberculin' vs 'saline'stimulusTranscriptional profiling of the tuberculin skin test in individuals cured of active tuberculosis disease (RNA-Seq)
Adjusted p-valueLog2-fold change
1.6777 × 10-41.1
NTF3'8 day' vs '0 day'timeGlobal expression profiling time series of early human embryonic stem cell differentiation towards the mesoderm lineage
Adjusted p-valueLog2-fold change
2.3382 × 10-4-1.1
NTF3'ETP-45658' vs 'DMSO'compoundGene expression profiling upon PI3K inhibition using different inhibitors
Adjusted p-valueLog2-fold change
3.2904 × 10-4-1.1
NTF3'chronic discoid lupus erythematosus' vs 'normal'clinical historyGene expression in cutaneous lupus erythematosus
Adjusted p-valueLog2-fold change
3.6239 × 10-4-1.1
NTF3'pBABE-puro-H-RasG12V transfected' vs 'control'genotypeTranscription profiling by array of Ras-induced human fibroblast cell line WI38 to analyse transcriptional changes in senescent cells
Adjusted p-valueLog2-fold change
1.8118 × 10-31.1
NTF3'Bmi1 knockdown' vs 'control'compound, genotype, timeTranscription profiling by array of human multiple myeloma cells after infection with a shRNA targeting BMI1
Adjusted p-valueLog2-fold change
3.7364 × 10-3-1.1
NTF3'NiO nanoparticles; 0.5 microgram per milliliter' vs 'none'compoundRNA-Seq of BEAS-2B cells treated with low doses of Ni and NiO nanoparticles as well as NiCl2 for 6 weeks
Adjusted p-valueLog2-fold change
8.9355 × 10-3-1.1
NTF3'esophageal adenocarcinoma' vs 'normal'disease, disease stagingWhole transcriptome profiling of Esophageal adenocarcinoma and Barrett's
Adjusted p-valueLog2-fold change
1.6665 × 10-21.1
NTF3'Tetralogy of Fallot' vs 'normal'diseaseRNA-seq of heart right ventricle from 22 patients with Tetralogy of Fallot and healthy individuals
Adjusted p-valueLog2-fold change
2.1356 × 10-21.1
NTF3'non primary Sjogren syndrome sicca' vs 'normal'block, diseaseTranscription profiling by array of parotid tissue from Primary Sjögren’s Syndrome and controls
Adjusted p-valueLog2-fold change
2.1781 × 10-21.1
NTF3'EPZ004777; 6.4 micromolar' vs 'dimethyl sulfoxide; 1E-08 molar' in 'PEO4'cell line, compoundFunctional effect of DOT1L pharmacological inhibition in ERα-positive Ovarian Cancer cells
Adjusted p-valueLog2-fold change
2.2531 × 10-21.1
NTF3'p63 knockdown by siRNA' vs 'scrambled siRNA' in 'BxPC-3'RNA interference, cell lineRNA-seq of human pancreatic cell lines, L3.6pl and BxPC-3, upon knockdown of p63 for 48 hours compared to siControl
Adjusted p-valueLog2-fold change
2.829 × 10-2-1.1
NTF3'brain-derived neurotrophic factor' vs 'none' at '2 hour'sampling time point, stimulusRNA-seq of human neurons derived from H9 embryonic stem cell lines treated with BDNF, TrkB agonist ZEB 85 or NT4 against untreated controls
Adjusted p-valueLog2-fold change
3.3298 × 10-21.1
NTF3'DISC1 exon 8 mut/mut' vs 'wild type' in 'neuron' at 'embryoid body, day 50'cell type, genotype, sampling time pointTranscriptome profiling of human neural progenitor cells and neurons with DISC1 interruption
Adjusted p-valueLog2-fold change
5.1423 × 10-7-1
NTF3'HFF1; cocultured with epithelial Cal51 cells' vs 'HFF1; normal'cell line, growth conditionSystem-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity
Adjusted p-valueLog2-fold change
9.242 × 10-6-1
NTF3'HFFF2; cocultured with epithelial MDAMB231 cells' vs 'HFFF2; normal'cell line, growth conditionSystem-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity
Adjusted p-valueLog2-fold change
5.4398 × 10-51
NTF3'MDAMB231; cocultured with fibroblast Wi38' vs 'MDAMB231; normal'cell line, growth conditionSystem-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity
Adjusted p-valueLog2-fold change
8.2238 × 10-51
NTF3'ICI 182,780; 1E-08 molar' vs 'dimethyl sulfoxide; 1E-08 molar' in 'PEO1'cell line, compoundFunctional effect of DOT1L pharmacological inhibition in ERα-positive Ovarian Cancer cells
Adjusted p-valueLog2-fold change
8.5031 × 10-51
NTF3'liver hemangioma' vs 'normal'diseaseIntegrated ordination of miRNA and mRNA expression profiles [mRNA]
Adjusted p-valueLog2-fold change
1.0597 × 10-41
NTF3'KLF17 overexpression' vs 'wild type phenotype' at '4 day'phenotype, timeRNA-seq of hESCs overexpressing inducible KLF17 versus uninduced controls.
Adjusted p-valueLog2-fold change
1.2484 × 10-4-1
NTF3'cisplatin; 100 micromolar' vs 'none' in 'TMEM45A knockdown by siRNA'RNA interference, compoundRNA-seq of human head and neck cancer cell line SQD9 knock-out for TMEM45A exposed to cisplatin
Adjusted p-valueLog2-fold change
1.5691 × 10-41
NTF3'SOX2 siRNA' vs 'negative control' in 'NTera-2'RNA interference, cell lineGene expression data from SOX2 knock-out 2102Ep and NTera-2 human embryonal carcinoma cell lines
Adjusted p-valueLog2-fold change
1.9094 × 10-4-1
NTF3'cisplatin; 100 micromolar' vs 'none' in 'scrambled siRNA'RNA interference, compoundRNA-seq of human head and neck cancer cell line SQD9 knock-out for TMEM45A exposed to cisplatin
Adjusted p-valueLog2-fold change
2.0523 × 10-41
NTF3'KLF17 overexpression' vs 'wild type phenotype' at '3 day'phenotype, timeRNA-seq of hESCs overexpressing inducible KLF17 versus uninduced controls.
Adjusted p-valueLog2-fold change
2.3931 × 10-4-1
NTF3'PI-103' vs 'DMSO'compoundGene expression profiling upon PI3K inhibition using different inhibitors
Adjusted p-valueLog2-fold change
1.4755 × 10-31
NTF3'10 day' vs '0 day'timeGlobal expression profiling time series of early human embryonic stem cell differentiation towards the mesoderm lineage
Adjusted p-valueLog2-fold change
1.6706 × 10-3-1
NTF3'neoplasm; malignant' vs 'normal tissue adjacent to neoplasm; non-malignant' in 'hepatocyte'cell type, phenotype, sampling siteViral Expression and Molecular Profiling in Liver Tissue versus Microdissected Hepatocytes in Hepatitis B Virus - Associated Hepatocellular Carcinoma
Adjusted p-valueLog2-fold change
1.838 × 10-31
NTF3'MDA-MB-231; docetaxel resistant' vs 'MDA-MB-231; control'cell line, phenotypeTranscription profiling by array of MCF-7 and MDA-MB-213 cells treated with docetaxel
Adjusted p-valueLog2-fold change
2.1722 × 10-3-1
NTF3'DAOY M2.1; MYC overexpression' vs 'DAOY; wild type'cell type, genotypeBone morphogenetic protein-7 is a MYC target with pro-survival functions in childhood medulloblastoma
Adjusted p-valueLog2-fold change
4.4821 × 10-3-1
NTF3'not-inflamed; interstitial cystitis' vs 'normal'clinical information, diseaseTranscription profiling by array of bladder tissue of patients with interstitial cystitis
Adjusted p-valueLog2-fold change
5.3282 × 10-3-1
NTF3'TDP-43 knock-down' vs 'control'genotype3'-end targeted sequencing of 6 control and 6 TDP-43 KD samples in HEK293
Adjusted p-valueLog2-fold change
6.239 × 10-31
NTF3'hypoxia' vs 'normoxia' in 'SNF96.2'cell line, growth conditionHypoxia and Intrinsic Transcriptomic Subtyping of Soft Tissue Sarcoma
Adjusted p-valueLog2-fold change
1.7044 × 10-2-1
NTF3'cancer tissue' vs 'surrounding noncancerous tissue' in 'hepatitis B virus induced hepatocellular carcinoma'clinical information, diseaseTranscription profiling by array of human hepatitis B virus (HBV) and hepatitis C virus (HCV) induced hepatocellular (HCC) carcinoma and surrounding noncancerous liver tissue.
Adjusted p-valueLog2-fold change
1.7452 × 10-2-1
NTF3'epithelial cell of small intestine' vs 'epithelial cell of large intestine' in 'foetal'cell type, developmental stageTranscriptional profiling by array of intestinal epithelial cells from foetal and paediatric gut
Adjusted p-valueLog2-fold change
2.3079 × 10-2-1
NTF3'tripeptide arginine-glycine-aspartic acid-modified alginate' vs 'monolayer'growth conditionTranscription profiling by array of human mesenchymal stem cells in 2D culture compared with two different alginate-based 3D scaffolds
Adjusted p-valueLog2-fold change
3.5385 × 10-2-1
NTF3'cultured with 3D BPH-1 epithelial acini' vs 'cultured without epithelial acini'growth conditionTranscription profiling by array of human stromal cells cultured with or without 3D BPH-1 prostate epithelial cells
Synonym
NGF2
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
Gene biotype
Design element
4908_at, 35041_at, 3402179, 11758373_s_at, g9845503_3p_at, ILMN_1809364, 206706_PM_at, 206706_at, 7953284, A_23_P360797, A_19_P00330048, 3402165, 3402164, 3402175, 3402167, 3402178, 3402166, 3402177, M37763_at, A_24_P530690, 3402172, 3402182, 3402151, 3402173
Reactome pathway ID