-4 | | SIAH1 | 'doxorubicin; 5 micomolar and T0901317; 5 micromolar' vs 'none' | compound | LXR mediated-signalling protects human hair follicles against doxorubicin-induced toxicity ex vivo |
-3.5 | | SIAH1 | 'doxorubicin; 5 micromolar' vs 'none' | compound | LXR mediated-signalling protects human hair follicles against doxorubicin-induced toxicity ex vivo |
-3.5 | | SIAH1 | 'deferoxamine; 100 nanomolar echinomycin' vs 'deferoxamine; none' | growth condition, treatment | Transcription profiling by array of human glioblastoma cells after stimulation with deferoxamine and treatment with polyamide 1, echinomycin, or HIF-1a siRNA |
-3.4 | | SIAH1 | '5 microgram per milliliter dose of actinomycin D' vs '5 percent dose of mannitol' | compound | Transcription profiling of human A549 lung cancer cells treated with actinomycin D and sapphyrin PCI-2050 a new class of tumor-selective inhibitors of gene expression. |
-2.9 | | SIAH1 | 'UV' vs 'none' in 'brct expression' | phenotype, stimulus | Transcriptional profiling by array of U2OS cells overexpressing the BRCT domain of PARP1 after UV radiation |
-2.7 | | SIAH1 | 'UV' vs 'none' in '(no brct expression) GFP control' | phenotype, stimulus | Transcriptional profiling by array of U2OS cells overexpressing the BRCT domain of PARP1 after UV radiation |
2.2 | | SIAH1 | 'p53KO; tunicamycin' vs 'p53KO; control' | genotype, treatment | Induction of ER stress in HCT116 colon cancer cells |
-2 | | SIAH1 | 'blood alcohol content 0%' vs 'control' in 'time point 1' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
-2 | | SIAH1 | 'blood alcohol content 0.02%declining' vs 'control' in 'time point 5' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
-2 | | SIAH1 | 'blood alcohol content 0.04%declining' vs 'control' in 'time point 4' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
1.9 | | SIAH1 | 'noradrenaline, 1 micromolar' vs 'none' | stimulus | Human primary adipose-derived stem cells (hpASC) differentiated to white adipocytes stimulated with norepinephrine 3h |
1.8 | | SIAH1 | 'siRNA double knockdown of HNF4A and GATA6' vs 'scrambled siRNA' | RNA interference | Total RNA-seq of human oesophageal adenocarcinoma cell line OE19 treated with siNT, siHNF4A, siGATA6 and siHNF4A+siGATA6 for 72 hours |
-1.8 | | SIAH1 | '12 hour' vs '0 hour' in 'MCF-10A' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
-1.8 | | SIAH1 | 'blood alcohol content 0.04%rising' vs 'control' in 'time point 2' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
-1.8 | | SIAH1 | 'atopic eczema; normal skin' vs 'normal; normal skin' | clinical information, disease, phenotype | Transcription profiling by array of acute and chronic atopic dermatitis compared to normal skin |
-1.8 | | SIAH1 | 'blood alcohol content 0.08%' vs 'control' in 'time point 3' | sampling time point, treatment | Microarray characterization of gene expression changes in blood during acute ethanol exposure |
1.8 | | SIAH1 | 'wild type; tunicamycin' vs 'wild type; control' | genotype, treatment | Induction of ER stress in HCT116 colon cancer cells |
1.7 | | SIAH1 | 'CB-5083; 5 micromolar' vs 'dimethyl sulfoxide' in 'sensitive to CB-5083' | compound, phenotype | RNA-seq of human ovarian cancer cell line OVSAHO parental and CB-5083-resistant cells |
-1.7 | | SIAH1 | 'colorectal carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
1.7 | | SIAH1 | 'wild type; BREFELDIN A' vs 'wild type; control' | genotype, treatment | Induction of ER stress in HCT116 colon cancer cells |
-1.6 | | SIAH1 | '12 hour' vs '0 hour' in 'MCF-10A-H1047R' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
-1.6 | | SIAH1 | 'erythroleukemia; ZRSR2 shRNA' vs 'normal' | disease, genotype | RNA-seq of bone marrow from patients with myelodysplastic syndrome |
1.6 | | SIAH1 | 'DICERER5/EX5; tunicamycin' vs 'DICERER5/EX5; control' | genotype, treatment | Induction of ER stress in HCT116 colon cancer cells |
1.5 | | SIAH1 | 'lipopolysaccharide; 20 nanogram per milliliter; stimulated; 24 hour' vs 'none; naive; 0 hour' | compound, stimulus, time | Genetics of gene expression across innate immune stimulation in primary monocytes |
-1.5 | | SIAH1 | 'pancreatic adenocarcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
-1.5 | | SIAH1 | 'acetaminophen; 18 millimolar' vs 'none' in 'hSKP-HPC; normal; skin' | cell line, compound, disease, organism part | Gene expression data from acetaminophen-induced toxicity in human hepatic in vitro systems and clinical liver samples |
1.4 | | SIAH1 | 'interferon gamma; 20 nanogram per milliliter; stimulated; 24 hour' vs 'none; naive; 0 hour' | compound, stimulus, time | Genetics of gene expression across innate immune stimulation in primary monocytes |
1.4 | | SIAH1 | 'MAGEA3 shRNA' vs 'scrambled shRNA' | RNA interference | RNA-seq of the human HCC cell line PLC5 after 72 hours treatment with either MAGEA3 shRNA or Scramble control |
1.4 | | SIAH1 | 'myxosarcoma' vs 'normal' | disease | Atrial Myxomas Arise From Multipotent Myxoid Cardiac Stem Cells |
1.4 | | SIAH1 | 'P-bodies (cytosolic RNP granules)' vs 'pre-sorted fraction' | fraction | RNA-Seq of purified P-bodies from HEK293 cells |
-1.4 | | SIAH1 | 'suberoylanilide hydroxamic acid' vs 'control' | compound | Vascular histone deacetylation by pharmacological HDAC inhibition [SAHA, RNA-seq] |
1.3 | | SIAH1 | 'CB-5083; 5 micromolar' vs 'dimethyl sulfoxide' in 'resistant to CB-5083' | compound, phenotype | RNA-seq of human ovarian cancer cell line OVSAHO parental and CB-5083-resistant cells |
-1.3 | | SIAH1 | 'cisplatin; 100 micromolar' vs 'none' in 'TMEM45A knockdown by siRNA' | RNA interference, compound | RNA-seq of human head and neck cancer cell line SQD9 knock-out for TMEM45A exposed to cisplatin |
1.3 | | SIAH1 | 'SARS coronavirus Urbani ΔORF6 mutant' vs 'mock' at '60 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
1.3 | | SIAH1 | 'abl; dihydrotestosterone; 16 hour' vs 'abl; vehicle' | RNA interference, cell line, compound, time | Transcription profiling by array of human LNCaP and abl cells after treatment with dihydrotestosterone or androgen receptor siRNA |
-1.3 | | SIAH1 | '24 hour' vs '0 hour' in 'MCF-10A-H1047R' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
-1.3 | | SIAH1 | 'glioblastoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
1.3 | | SIAH1 | 'SARS coronavirus Urbani ΔORF6 mutant' vs 'mock' at '54 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
1.3 | | SIAH1 | 'SARS coronavirus Urbani ΔORF6 mutant' vs 'mock' at '72 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
-1.3 | | SIAH1 | 'neoplasm' vs 'normal tissue adjacent to neoplasm' | sampling site | Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma |
-1.3 | | SIAH1 | 'influenza A virus' vs 'none' in 'wild type' | genotype, infect | Transcription profiling by array of HUVEC cells after infection with H5N1 influenza virus |
-1.3 | | SIAH1 | 'trichostatin A; 500 nanomolar' vs 'control' | compound | Transcription profiling by high throughput sequencing of human aortic endothelial cell treated with TSA |
-1.3 | | SIAH1 | 'Ataxia-telangiectasia' vs 'normal' | disease | Ataxia-telangiectasia cerebellar cortex expression |
1.2 | | SIAH1 | 'Sorafenib; 5 micromolar' vs 'vehicle' in 'HuH-7' | cell line, compound | RNA-seq of human hepatocellular carcinoma cell line Huh7 and immortalized hepatocyte cell line THLE5B treated with experimental compound AD80, Sorafenib, and vehicle for 24 hours |
1.2 | | SIAH1 | '1 microgram per milliliter; lipopolysaccharide' vs 'none' in 'control' | compound, growth condition | Transcription profiling by array of human dendritic cells co-cultured with carcinoma cells or treated with lipopolysaccharide |
1.2 | | SIAH1 | 'human transforming growth factor beta 1' vs 'control' in 'chondrocyte' at '384 hour' | block, cell type, growth condition, time | Gene Expression underlying Osteo-, Adipo-, and Chondro-Genic Lineage Commitment of Human Mesenchymal Stem Cells |
1.2 | | SIAH1 | 'group 4 medulloblastoma' vs 'normal' | disease | Gene expression profile of pediatric and adult brain tumor types and normal brain |
1.2 | | SIAH1 | 'deprived of Methionine' vs 'control media' in 'MCF7' at '24 hour' | cell line, growth condition, time | Transcription profiling by array of human MCF-7 and PC3 cells grown under amino acid deprived or rich conditions for 24 or 48 hours |
1.2 | | SIAH1 | 'IL4 and dexamethasone' vs 'IL4 only' at '0 hour' | compound, growth condition, time | Transcription profiling by array of human primary macrophages after treatment with TGF-beta |
-1.2 | | SIAH1 | 'tongue squamous cell carcinoma' vs 'normal' in 'vehicle' | compound, disease | Transcription profiling by high throughput sequencing of retinoic acid treated human oral squamous cell carcinoma cells and normal cells |
-1.2 | | SIAH1 | 'expressing O6-methylguanine methyltransferase' vs 'control' | phenotype | MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib |
-1.2 | | SIAH1 | '1,25-dihydroxyvitamin D3; 10 nanomolar' vs 'vehicle' in 'immature dentritic cell' at '5 day' | cell type, compound, time | Transcription profiling by array of human monocyte-derived dendritic cells treated with 1,25-dihydroxyvitamin D3 |
-1.1 | | SIAH1 | 'chronic kidney disease' vs 'normal' | disease | Expression data from uremic patients (end stage renal failure) and 20 healthy controls |
-1.1 | | SIAH1 | 'cisplatin; 100 micromolar' vs 'none' in 'scrambled siRNA' | RNA interference, compound | RNA-seq of human head and neck cancer cell line SQD9 knock-out for TMEM45A exposed to cisplatin |
1.1 | | SIAH1 | 'poly(I:C); 25 microgram per milliliter' vs 'none' in 'none; none' | compound, infect, stimulus | RNA-seq of H1N1 infected monocyte-derived dendritic cells (MoDC), stimulated with single-stranded oligonucleotides (ssON) and/or Poly I:C. |
1.1 | | SIAH1 | 'valproic acid; 15 millimolar' vs 'control' at '3 day' | compound, sampling time point | RNA-seq of Primary Human Hepatocytes (PHH) exposed to Valproic Acid (VPA) for 3 days daily and 3 days daily exposure followed by 3 days washout. |
1.1 | | SIAH1 | '20 μM Methionine media' vs 'control media' in 'PC3' at '24 hour' | cell line, growth condition, time | Transcription profiling by array of human MCF-7 and PC3 cells grown under amino acid deprived or rich conditions for 24 or 48 hours |
-1.1 | | SIAH1 | 'non-small cell lung carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
1.1 | | SIAH1 | 'Mycobacterium tuberculosis' vs 'none' in 'dendritic cell' at '48 hour' | cell type, infect, time | Transcription profiling by array of human dendritic cells and macrophages infected with Mycobacterium tuberculosis |
-1.1 | | SIAH1 | 'H5N1 influenza virus' vs 'none' in 'wild type' | genotype, infect | Transcription profiling by array of HUVEC cells after infection with H5N1 influenza virus |
1.1 | | SIAH1 | 'SARS coronavirus Urbani ΔORF6 mutant' vs 'mock' at '48 hour' | infect, time | Time course analysis of icSARS CoV Urbani or icSARS deltaORF6 infected Calu-3 2B4 bronchial epithelial cells |
-1.1 | | SIAH1 | 'plasma cell' vs 'memory B cell' | cell type | Transcription profiling by array of human activated B cells, plasmablasts and plasma cells compared to memory B cells |
-1.1 | | SIAH1 | 'ovarian cancer' vs 'normal' in 'epithelial cell' | cell type, disease | A cancer associated fibroblasts (CAFs) specific gene signature in high grade serous ovarian cancer |
-1.1 | | SIAH1 | 'NLRC4-Macrophage Activation Syndrome; prior to anakinra treatment' vs 'normal' | disease, treatment | An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome |
-1.1 | | SIAH1 | 'Francisella tularensis Schu S4' vs 'uninfected' | infect | Transcription profiling by array of human peripheral blood mononuclear cells infected with Francisella tularensis |
1 | | SIAH1 | 'lipopolysaccharide; 20 nanogram per milliliter; stimulated; 2 hour' vs 'none; naive; 0 hour' | compound, stimulus, time | Genetics of gene expression across innate immune stimulation in primary monocytes |
-1 | | SIAH1 | 'H9; hepatocyte-like cell; hepatocyte-like cell foci' vs 'H9; embryonic stem cell' | block, cell line, cell type, fraction | Gene expression profile of human embryonic stem cell-derived hepatocyte-like cells |
1 | | SIAH1 | 'Crohn's disease' vs 'normal' | disease | RNA-seq of formalin-fixed, paraffin-embedded uninvolved terminal ileal tissue obtained from ileo-colic resection surgeries of Crohns disease and control patients |
1 | | SIAH1 | 'expression of estrogen receptor beta fused to C terminus tandem affinity purification tag' vs 'expression of estrogen receptor alpha fused to C terminus tandem affinity purification tag' | genotype | The nuclear receptor ERbeta engages AGO2 in regulation of gene transcription, RNA splicing and RISC loading. Part 4 |
-1 | | SIAH1 | 'adult; burn; middle stage' vs 'adult; control' | developmental stage, injury, sampling time point | Gene expression of blood samples from pediatric and adult patients with severe burns collected at an early and middle stage after injury. |
1 | | SIAH1 | 'medulloblastoma' vs 'normal' | disease | Expression data from human brain tumors and human normal brain |
-1 | | SIAH1 | 'AsPC-1; pancreatic adenocarcinoma; P04' vs 'AsPC-1; pancreatic adenocarcinoma; P0' | cell line, disease, passage | Microarray analysis of xenograft models in use at the Developmental Therapeutics Program of the National Cancer Institute (DTP-NCI) |
-1 | | SIAH1 | '7 hour' vs '0 hour' in 'MDA-LM2' | cell line, time | Transcription profiling by high throughput sequencing in MDA-MB-231 and MDA-LM2 cell lines |
-1 | | SIAH1 | '6 hour' vs '0 hour' in 'MCF-10A-H1047R' | cell line, time | Knock-in of PIK3CA-H1047R into MCF-10A |
1 | | SIAH1 | 'rotenone; 50 nanomolar' at '4 week' vs 'vehicle; ' at '4 week' | compound, time | Transcriptome analysis of a chronic in vitro model of Parkinsonism |
-1 | | SIAH1 | 'breast carcinoma' vs 'normal' | block, disease | RNA-seq of blood platelets from six tumor types and healthy donors |
1 | | SIAH1 | 'chronic lymphocytic leukemia' vs 'normal' in 'B lymphocytes' | cell type, disease | Gene expression profiling of B lymphocytes and plasma cells from Waldenstrons macroglobulinemia. |
-1 | | SIAH1 | 'BRD4 inhibitor JQ1' vs 'none' in 'OMM1' | cell line, compound | Transcription profiling by array of uveal melanoma cell lines with wild type and mutant G-proteins (GNAQ or GNA11) in response to treatment with BRAD4 inhibitor JQ1 |
1 | | SIAH1 | 'sonic hedgehog group medulloblastoma' vs 'normal' | disease | Gene expression profile of pediatric and adult brain tumor types and normal brain |
1 | | SIAH1 | 'psoriasis' vs 'normal' in 'Ovation RNA Amplification V2 kit' | disease, protocol | Dominant Th1 and Minimal Th17 Skewing in Discoid Lupus Revealed by Transcriptomic Comparison with Psoriasis |
-1 | | SIAH1 | 'T-helper 2 polarising' at '5 days' vs 'no stimulus' | cell type, sampling time point, stimulus | Transcription profiling by array of human CD4+T-cells, Th1/Th2 polarized time-series and primary memory subsets |
1 | | SIAH1 | 'bone marrow' vs 'cord blood' | cell line, organism part | Gene expression in pediatric cALL |
1 | | SIAH1 | 'tumor' vs 'normal' | clinical information | Transcription profiling by high throughput sequencing in esophageal squamous cell carcinoma cells. |
1 | | SIAH1 | 'Streptococcus gordonii' vs 'sham infection' | infect | Transcription profiling by array of human gingival epithelial cell responses to a complex microbiome |
-1 | | SIAH1 | 'expression of BRAF(V600E) and MITF' vs 'expression of BRAF(V600E)' | phenotype | Gene expression profile of MITF expressing cells |
