ENSMUSG00000001520 (Nrip2)

mus musculus

nuclear receptor interacting protein 2

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Mus musculus
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Showing 9 experiments:
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Created with Highcharts 6.2.0brainbrown adipose tissuecaudal brain neural epitheliumcentral neural epitheliumcolondentate gyrus of hippocampal formationdorsal control neural epitheliumepidermal ectodermfloor platehead mesenchymeheartkidneylateral nasal prominencelateral prominence neural epitheliumliverlungmandibular archmaxillary archmedial nasal prominencemesodermnon-floor plate neural epitheliumolfactory bulbolfactory pitskeletal muscle tissuespleenstriatumsubventricular zonetestisthymuswhite adipose tissuezone of skin
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14 - embryonic day 10.5
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9 in 3 strains - DBA/2J
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14 - embryonic day 8.5
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Fat and muscle
T
9 in 3 strains - CD1
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9 in 3 strains - C57BL/6
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9
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4
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14 - embryonic day 9.5
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Proteomics
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Transcriptomics
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-3.4
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.3087 × 10-783.6
Nrip2'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1'cell type, growth condition, phenotypeTranscription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture
Adjusted p-valueLog2-fold change
7.8684 × 10-3-3.4
Nrip2'neural stem cell' vs 'niche cell'cell typeTranscription profiling by high throughput sequencing of three populations of primary dentate gyrus cells
Adjusted p-valueLog2-fold change
1.7388 × 10-2-3.3
Nrip2'pabpn1l -/-' vs 'wild type genotype' in 'zygote'genotype, organism partRNA-seq of oocytes and zygotes from pabpn1l ko and wt female mice
Adjusted p-valueLog2-fold change
2.2065 × 10-73.2
Nrip2'pkd1 knockout' vs 'wild type' in 'presence of fluid flow'genotype, stimulusTranscription profiling by array of mouse kidney epithelial cells from pkd1 knockout and wild type in response to fluid flow
Adjusted p-valueLog2-fold change
1.4651 × 10-3-3
Nrip2'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '1.5 to 3 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
2.5607 × 10-12-2.9
Nrip2'Plasmodium berghei' vs 'none' in 'none'compound, infectTranscription profiling by array of mouse blood infected with Plasmodium berghei after treatment with activated charcoal
Adjusted p-valueLog2-fold change
3.1913 × 10-52.9
Nrip2'pkd1 knockout' vs 'wild type' in 'absence of fluid flow'genotype, stimulusTranscription profiling by array of mouse kidney epithelial cells from pkd1 knockout and wild type in response to fluid flow
Adjusted p-valueLog2-fold change
5.9387 × 10-62.8
Nrip2'liver-specific Cnot1 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
1.5929 × 10-4-2.8
Nrip2'extracellular vesicle; EMT cell culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
1.3162 × 10-52.7
Nrip2'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
2.8094 × 10-22.7
Nrip2'metaphase II oocyte' vs 'germinal vesicle oocyte'cell typeTranscription profiling of mouse in vivo matured MII oocytes and fully in vivo grown germinal vesicle oocytes to identify gene transcripts linked to epigenetic reprogramming
Adjusted p-valueLog2-fold change
9.8592 × 10-3-2.6
Nrip2'induction of polymicrobial sepsis' vs 'control' at '72 hour' in '20 to 24 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
3.5426 × 10-22.6
Nrip2'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
7.199 × 10-142.4
Nrip2'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
2.7936 × 10-52.4
Nrip2'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
5.1779 × 10-102.2
Nrip2'carotid body' vs 'adrenal medulla'organism partExpression profile of mouse carotid body and adrenal medulla [RNA-Seq]
Adjusted p-valueLog2-fold change
1.8078 × 10-62.2
Nrip2'6 day; osteogenesis differentiation' vs ' 0 day; control' in '2C12-pMirn0'cell line, growth condition, timeEffect of Mirn378 overexpression on gene expression during C2C12 myogenic and BMP2-induced osteogenic differentiation
Adjusted p-valueLog2-fold change
3.2744 × 10-2-2.1
Nrip2'XBP1s overexpression' vs 'wild type genotype' in '4μ8C; 15 micromolar'compound, genotypeOverexpression of spliced XBP1 in in vitro Th2 cells, and comparison to 4u8c treatment
Adjusted p-valueLog2-fold change
1.339 × 10-7-1.9
Nrip2'Notch3 homozygous knockout' vs 'wild type genotype' in 'cerebellar microvascular fragments'genotype, organism partTranscription profiling by array of cerebral and cerebellar microvascular fragments from mice with Notch3 homozygous knockout vs samples from control, wild-type littermates
Adjusted p-valueLog2-fold change
4.4626 × 10-4-1.9
Nrip2'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
3.3792 × 10-2-1.9
Nrip2'30 month' vs '5 month' in 'male'age, block, sexExpression data from tail skin in young (5 months) and old (30 months) CB6F1 mice
Adjusted p-valueLog2-fold change
1.0519 × 10-2-1.8
Nrip2'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'bER knockout'compound, genotypeLaser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries
Adjusted p-valueLog2-fold change
2.799 × 10-21.8
Nrip2'B4053; RML infected' at '6 week' vs 'B4053; uninfected' at '6 week'strain, time, treatmentTranscription profiling of mouse brain infected with prions in eight mouse-prion strain combinations in a systems approach to the study of prion disease
Adjusted p-valueLog2-fold change
3.6533 × 10-21.8
Nrip2'Macrophage of F4/80+, CD11b+, CD11c-+; obese leptin-deficient' vs 'Macrophage of F4/80+, CD11b+, CD11c-+; control'cell type, genotypeExpression data from mouse adipose tissue macrophage
Adjusted p-valueLog2-fold change
1.6176 × 10-4-1.6
Nrip2'Notch3 homozygous knockout' vs 'wild type genotype' in 'cerebral microvascular fragments'genotype, organism partTranscription profiling by array of cerebral and cerebellar microvascular fragments from mice with Notch3 homozygous knockout vs samples from control, wild-type littermates
Adjusted p-valueLog2-fold change
1.2691 × 10-2-1.6
Nrip2'status epilepticus' vs 'none' in 'astrocyte; soticlestat; 30 milligram per kilogram'cell type, compound, diseaseRNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment
Adjusted p-valueLog2-fold change
2.1695 × 10-4-1.5
Nrip2'cut nerve; 7 day' vs 'none'injury, protocol, timeChanges in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury
Adjusted p-valueLog2-fold change
1.4236 × 10-41.4
Nrip2'24 hour' vs '0 hour' in 'WT1-KTS'genotype, timeEWS-WT1 Oncogene Activates a Neuronal Reprogramming Factor ASCL1 and Mediates Partial Neural Differentiation
Adjusted p-valueLog2-fold change
1.0386 × 10-31.4
Nrip2'R6/2 transgenic' vs 'wild type' in '12 week; striatum'age, genotype, organism partTranscription profiling by high throughput sequencing in wild type and R6/2 mutant mouse cortex and striatum at 8 and 12 weeks.
Adjusted p-valueLog2-fold change
1.289 × 10-3-1.4
Nrip2'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
3.1348 × 10-31.4
Nrip2'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
8.105 × 10-31.4
Nrip2'ICG-001 and PHA665752' vs 'DMSO'compoundTranscription profiling by array of mammospheres derived from tumors of mice harboring Wnt/Met signaling mutations treated Wnt and MET pathway inhibitors
Adjusted p-valueLog2-fold change
7.1994 × 10-4-1.3
Nrip2'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J'phenotype, stimulus, strainRNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail
Adjusted p-valueLog2-fold change
6.325 × 10-3-1.3
Nrip2'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
5.8107 × 10-61.2
Nrip2'none; wasp knockout' vs 'none; wild type'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
2.3401 × 10-31.2
Nrip2'5,9-endoperoxy-cholest-7-en-3β,6α-diol' vs 'vehicle (cyclodextrin)'compound, timeArray results for differential gene expression in 661W, a mouse cone photoreceptor-derived cell line, comparing cells incubated with vehicle controls vs. those treated with either of two 7-dehdyrocholesterol-derived oxysterols or cholesterol
Adjusted p-valueLog2-fold change
2.6625 × 10-31.2
Nrip2'Crx knockout' vs 'control' at '6 zeitgeber'genotype, timeTranscriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20
Adjusted p-valueLog2-fold change
6.8894 × 10-3-1.2
Nrip2'osteoblast culture 27 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
4.419 × 10-2-1.2
Nrip2'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '20 to 24 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
2.5793 × 10-41.1
Nrip2'Mef2c deletion' vs 'wild type'phenotypeWhole transcriptome sequencing of mouse regulatory T cells with and without Mef2d, Mef2c, HDAC1, HDAC2 or Dyrk1 deletion
Adjusted p-valueLog2-fold change
4.1766 × 10-31.1
Nrip2Synacthen vs sodium chloride controlcompoundTranscription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses.
Adjusted p-valueLog2-fold change
4.4022 × 10-3-1.1
Nrip2'Notch3 knockout' vs 'wild type'genotypeExpression data from caudal artery of Notch3WT and Notch3KO mice
Adjusted p-valueLog2-fold change
7.2362 × 10-3-1.1
Nrip2'osteoblast culture 9 day' vs '0 day'timeTranscription profiling by array of mouse primary neonatal osteoblasts to study the regulation of bone mineralisation
Adjusted p-valueLog2-fold change
7.3196 × 10-3-1.1
Nrip2'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre-'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
3.094 × 10-2-1.1
Nrip2'lung carcinoma' vs 'normal' in 'lung cell'cell type, diseaseTranscriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq
Adjusted p-valueLog2-fold change
2.8809 × 10-71
Nrip2'Kit ligand; wasp knockout' vs 'Kit ligand; wild type'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
2.8878 × 10-7-1
Nrip2'chronic pancreatitis' vs 'control'diseasePancreatic gene expression associated with cerulein induced chronic pancreatitis in mice
Adjusted p-valueLog2-fold change
1.9127 × 10-6-1
Nrip2'embryo transfer' vs 'no embryo transfer'stimulusRNA-seq of whole mouse placentas at E10.5 comparing C57Bl/6 male conceptuses that had undergone blastocyst transfer to non-transferred C57Bl/6 male conceptuses
Adjusted p-valueLog2-fold change
2.4873 × 10-5-1
Nrip2'transgenic' vs 'wild type' in '121 day; 129Sv'age, genotype, strainWhole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models
Adjusted p-valueLog2-fold change
3.1893 × 10-3-1
Nrip2'Sik1 knockout; gonad adipose tissue' vs 'wild type genotype; gonad adipose tissue'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
6.2106 × 10-31
Nrip2"tunicamycin; 2 microgram per milliliter" vs "DMSO" in "PWK/PhJ"compound, strainTranscription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress
Adjusted p-valueLog2-fold change
7.2958 × 10-31
Nrip2'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
4.4924 × 10-2-1
Nrip2'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre+'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα