ENSMUSG00000006005 (Tpr)

mus musculus

translocated promoter region, nuclear basket protein

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Mus musculus
Organism part
Showing 9 experiments:
Created with Highcharts 6.2.0brainbrown adipose tissuecaudal brain neural epitheliumcentral neural epitheliumcolondentate gyrus of hippocampal formationdorsal control neural epitheliumepidermal ectodermfloor platehead mesenchymeheartkidneylateral nasal prominencelateral prominence neural epitheliumliverlungmandibular archmaxillary archmedial nasal prominencemesodermnon-floor plate neural epitheliumolfactory bulbolfactory pitskeletal muscle tissuespleenstriatumsubventricular zonetestisthymuswhite adipose tissuezone of skin
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14 - embryonic day 10.5
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9 in 3 strains - DBA/2J
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14 - embryonic day 8.5
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Fat and muscle
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9 in 3 strains - CD1
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9 in 3 strains - C57BL/6
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9
T
4
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14 - embryonic day 9.5
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Proteomics
T
Transcriptomics
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-1
-2.4
1
1.7
Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
6.023 × 10-14-2.4
Tpr'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
2.3457 × 10-5-1.8
Tpr'normobaric hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo.
Adjusted p-valueLog2-fold change
1.3005 × 10-51.7
Tpr'chronic pancreatitis' vs 'control'diseasePancreatic gene expression associated with cerulein induced chronic pancreatitis in mice
Adjusted p-valueLog2-fold change
1.7072 × 10-5-1.7
Tpr'alpha-amanitin; maternal Ring1-Rnf+' vs 'none; maternal Ring1-Rnf+'compound, genotypePolycomb function during oogenesis is required for mouse early embryonic development (2-cell embryos)
Adjusted p-valueLog2-fold change
7.8679 × 10-4-1.7
Tpr'subarachnoid hemorrhage' vs 'normal'diseaseTranscription profiling by array of the effect of SAH on brain cells in white matter region of mice
Adjusted p-valueLog2-fold change
5.5382 × 10-3-1.7
Tpr'48 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
3.2666 × 10-21.7
Tpr'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
9.7861 × 10-24-1.6
Tpr'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
7.004 × 10-31.6
Tpr'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
6.867 × 10-16-1.5
Tpr'actinomycin D; 4 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
6.6512 × 10-11-1.5
Tpr'AZD5069; 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
1.5698 × 10-3-1.5
Tpr'96 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
2.5841 × 10-21.5
Tpr'neural stem cell' vs 'niche cell'cell typeTranscription profiling by high throughput sequencing of three populations of primary dentate gyrus cells
Adjusted p-valueLog2-fold change
6.5036 × 10-101.4
Tpr'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant'disease, stimulusRNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice
Adjusted p-valueLog2-fold change
2.1524 × 10-71.4
Tpr'mutant MyoD expression' at '12 hour' vs 'wild type MyoD expression' at '0 hour'phenotype, timeTranscription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation.
Adjusted p-valueLog2-fold change
3.2126 × 10-61.4
Tpr'confluent monolayer on collagen' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
9.6385 × 10-61.4
Tpr'confluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.7005 × 10-51.4
Tpr'Duchenne muscular dystrophy' vs 'normal'diseaseRNA-seq comparison of immortalised myoblasts from dystrophic and WT mice
Adjusted p-valueLog2-fold change
3.4206 × 10-41.4
Tpr'2,3-Benzofuran; 240 milligram per kilogram; corn oil' vs 'none; ; corn oil'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
4.1524 × 10-3-1.4
Tpr'mutant MyoD expression' at '6 hour' vs 'control' at '6 hour'phenotype, timeTranscription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation.
Adjusted p-valueLog2-fold change
5.0407 × 10-114-1.3
Tpr'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte'cell type, compound, genotypeTranscription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin
Adjusted p-valueLog2-fold change
1.0735 × 10-4-1.3
Tpr'Runx1 knockdown; induce erythroid differentiation' vs 'wild type; induce erythroid differentiation'genotype, stimulusTranscription profiling by array of Mouse erythro-leukaemia cells during differentiation to investigate the influence of Runx1 transcription factor
Adjusted p-valueLog2-fold change
5.513 × 10-51.2
Tpr'confluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
9.7297 × 10-4-1.2
Tpr'Fhl1 knockdown by siRNA' vs 'wild type' at '1 day'phenotype, time3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1
Adjusted p-valueLog2-fold change
5.0276 × 10-31.2
Tpr'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'bER knockout'compound, genotypeLaser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries
Adjusted p-valueLog2-fold change
2.6729 × 10-21.2
Tpr'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
2.907 × 10-81.1
Tpr'extracellular vesicle; EMT cell culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
7.1144 × 10-61.1
Tpr'methionine- and choline-deficient, high fat diet' vs 'normal'dietExpression data from mouse liver treated with metformin
Adjusted p-valueLog2-fold change
1.078 × 10-51.1
Tpr'confluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.8024 × 10-41.1
Tpr'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.8987 × 10-31.1
Tpr'left ventricle' vs 'right ventricle' in 'embryonic day 14.5'developmental stage, organism partTranscriptional Atlas of Cardiogenesis Maps Congenital Heart Disease Interactome
Adjusted p-valueLog2-fold change
2.6153 × 10-31.1
Tpr'Rb;E2f8 knock-out' vs 'wild type'genotypeExpression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells
Adjusted p-valueLog2-fold change
3.1342 × 10-3-1.1
Tpr'24 hour after induction of differentiation' vs 'induction of differentiation'compound, sampling time pointExpression Profiling of Early Myogenesis - Affymetrix Dataset
Adjusted p-valueLog2-fold change
3.188 × 10-21.1
Tpr'DAPT' vs 'dimethyl sulfoxide' in 'Ngn3tTA/tTA'compound, genotypeNeurog3-independant role of Notch signaling in pancreas explants. Microarray of pancreata of Wildtype or Neurog3tTA/tTA (Neurog3-Null) background at E12.5, explanted for 3d + treatment 24h with DAPT/vehicle.
Adjusted p-valueLog2-fold change
8.9084 × 10-201
Tpr'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
2.3309 × 10-141
Tpr'nuclear translocation of Mbd3b' at '48 hour' vs 'none' at '0 hour'stimulus, timeTranscription profiling by RNA-seq during NuRD complex induction in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
4.2326 × 10-141
Tpr'nuclear translocation of Mbd3b' at '24 hour' vs 'none' at '0 hour'stimulus, timeTranscription profiling by RNA-seq during NuRD complex induction in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
2.4646 × 10-8-1
Tpr'216 hour' vs '0 hour' on 'Affymetrix Mouse430A_2 Array'timeTranscription profiling of murine J1 embryonic stem cells undergoing a differentiation time course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
1.2819 × 10-4-1
Tpr'reduced expression of miR-25' vs 'wild type'phenotypeTranscription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice
Adjusted p-valueLog2-fold change
4.436 × 10-4-1
Tpr'mutant MyoD expression' at '24 hour' vs 'control' at '24 hour'phenotype, timeTranscription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation.
Adjusted p-valueLog2-fold change
2.984 × 10-3-1
Tpr'Stella maternal / zygotic knockout' vs 'wild type genotype' in '2-cell embryo'developmental stage, genotypeTranscription profiling of wild type and Stella knockout oocytes, wild type and Stella maternal/zygotic knockout embryos to study to the role of Stella in early mouse development
Adjusted p-valueLog2-fold change
3.8066 × 10-3-1
Tpr'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
4.2968 × 10-3-1
Tpr'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
2.6263 × 10-21
Tpr'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '1.5 to 3 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
3.2545 × 10-2-1
Tpr'induction of polymicrobial sepsis' vs 'control' at '2 hour' in '20 to 24 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
4.0392 × 10-2-1
Tpr'carboplatin; 30 milligram per kilogram' vs 'none' in '14 week; none'age, irradiatePericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence
Adjusted p-valueLog2-fold change
4.3879 × 10-2-1
Tpr'SARS coronavirus MA15 lacking full-length E protein' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains