-8.1 | | Xk | '5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a' | genotype, time | RNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating |
6.2 | | Xk | 'SMRT shRNA' vs 'none' in 'CpG' at '6 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
-3.8 | | Xk | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
3.7 | | Xk | 'SMRT shRNA' vs 'none' in 'none' at '0 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
-3.6 | | Xk | 'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-3.5 | | Xk | 'clear cell sarcoma; TATCre' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
3.5 | | Xk | 'SMRT shRNA; CpG; 6 hour' vs 'none; none; 0 hour' | RNA interference, stimulus, time | RNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation |
3.4 | | Xk | 'erythroblast' vs 'hematopoietic stem cell' | cell type | Transcription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells |
-3.3 | | Xk | 'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-3.3 | | Xk | 'Duchenne muscular dystrophy' vs 'normal' | disease | RNA-seq comparison of immortalised myoblasts from dystrophic and WT mice |
-2.8 | | Xk | '21 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-2.7 | | Xk | 'extracellular vesicle; non-stimulated culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-2.4 | | Xk | 'clear cell sarcoma; Rosa26CreER' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-2.4 | | Xk | '180 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-2.4 | | Xk | '30 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
2.4 | | Xk | 'Influenza A virus' vs 'none' | infect | RNA-seq of mouse alveolar macrophages from control and Influenza A virus infected animals |
2.3 | | Xk | '1810027O10Rik knockout; gonad adipose tissue' vs 'wild type genotype; gonad adipose tissue' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
2.3 | | Xk | 'NrlGFP positive' vs 'NrlGFP negative' | phenotype | Transcription profiling by array of photoreceptor precursor cells selected via cell surface antigen expression. |
-2.3 | | Xk | '365 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-2.3 | | Xk | '730 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-2.3 | | Xk | 'osteosarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-2.2 | | Xk | '90 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-2.2 | | Xk | '60 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
-2.2 | | Xk | 'PTEN null, P53-/-' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
-2.1 | | Xk | '14 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
2.1 | | Xk | 'Cbs knockout' vs 'wild type' | genotype | Gene expression profile of CD4-positive T cells from mouse Cbs knockout |
2 | | Xk | 'hypobaric hypoxia' vs 'control' | growth condition | Comparison of gene expression in whole blood of mice subjected to hypobaric hypoxia at Mt. Everest in vivo. |
-1.9 | | Xk | 'colitis' at '8 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
-1.9 | | Xk | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.8 | | Xk | 'Triple knockout (Zfp36-/-, TNFR1-/-, TNFR2-/-)' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing of douple (TNFR1-/-/TNFR2-/-) and triple (Zfp36-/-/TNFR1-/-/TNFR2-/-) knockout mouse spleens |
-1.8 | | Xk | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
-1.7 | | Xk | 'Irx3 knockout' vs 'control' at '1 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
-1.7 | | Xk | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-1.6 | | Xk | 'extracellular vesicle; EMT cell culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
1.6 | | Xk | 'dexamethasome' vs 'methyl beta-clodextrin' in 'Nr1d1 homozygous knockout; 1 milligram per kilogram; ZT6' | compound, genotype, time | RNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment |
1.6 | | Xk | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
-1.5 | | Xk | 'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide' | compound, phenotype | Resistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition |
1.5 | | Xk | 'mir181a1/b1 Knockout' vs 'wild type' | genotype | Mouse CD4+/CD8+ thymocytes from miR-181a1/b1 KO vs WT |
-1.5 | | Xk | 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 3 day' vs 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 0 day' | cell type, compound, time | Drug tolerance development of mouse Bcr/Abl pre-B ALL cells on irradiated MEFs |
1.5 | | Xk | "YFP positive" vs "YFP negative" in "lamina propria of small intestine" | organism part, phenotype | Bulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages |
-1.5 | | Xk | 'carotid body' vs 'adrenal medulla' | organism part | Expression profile of mouse carotid body and adrenal medulla [RNA-Seq] |
-1.4 | | Xk | 'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide' | compound, phenotype | Resistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition |
1.4 | | Xk | 'Nrl-/-' vs 'wild type' | genotype | Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and Nrl-/- Retinal Transcriptomes |
-1.4 | | Xk | 'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1' | cell type, growth condition, phenotype | Transcription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture |
-1.4 | | Xk | 'heterozygous RYR1 mutant' vs 'RYR1 wild type' in 'embryonic day 14.5' | developmental stage, genotype | Microarrays of mouse embryonic limb skeletal muscle at days E14.5 and E18.5 lacking the RYR1 or Cav1.1 Ca2+ channels |
-1.4 | | Xk | '12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
-1.4 | | Xk | 'AZD5069; 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
-1.4 | | Xk | 'homozygous RYR1 mutant' vs 'RYR1 wild type' in 'embryonic day 14.5' | developmental stage, genotype | Microarrays of mouse embryonic limb skeletal muscle at days E14.5 and E18.5 lacking the RYR1 or Cav1.1 Ca2+ channels |
1.4 | | Xk | 'transplanted secondary tumors' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
1.4 | | Xk | 'chemical hypoxia' vs 'control' | growth condition | Comparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo. |
-1.4 | | Xk | 'dmrt1 knockout' vs 'wild type' in '129Sv' | genotype, strain | Dmrt1 (doublesex and mab-3 related transcription factor 1) conditional knockout expression analysis of E15.5 testes. |
-1.3 | | Xk | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
1.3 | | Xk | 'Ubc9 overexpression' vs 'wild type genotype' in 'undifferentiated; oxygen/glucose-deprivation followed by restoration of oxygen/glucose' | genotype, growth condition, stimulus | SUMOylation promotes survival and integration of neural stem cell grafts in stroke |
-1.3 | | Xk | 'ko cyld-/-' vs 'wild type' | genotype | Transcription profiling by array of mouse liver with Cyld inactivation |
1.3 | | Xk | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'A/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1.2 | | Xk | 'CD4-positive T cell' vs 'CD8-positive T cell' in 'Egr2-GFP knockin; Egr2-GFP high' | cell type, genotype, phenotype | RNAseq analysis of CD4 and CD8 T cells in response to vaccinia virus infection |
1.2 | | Xk | 'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
-1.2 | | Xk | 'TGFβ, 5 nanogram per milliliter' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-1.2 | | Xk | 'LDB1 knock-down' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
1.2 | | Xk | 'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'neutrophil' | cell type, genotype | RNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice |
-1.2 | | Xk | 'tumor' vs 'normal' in 'liver' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
-1.2 | | Xk | '7 day' vs '1 day' | age | Transcriptional profilling of female mice liver as a function of age |
1.2 | | Xk | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'SWR/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
1.2 | | Xk | 'V6.5; embryonic stem cell’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
1.2 | | Xk | 'dexamethasome' vs 'methyl beta-clodextrin' in 'wild type genotype; 1 milligram per kilogram; ZT6' | compound, genotype, time | RNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment |
-1.2 | | Xk | "muscularis externa layer of small intestine" vs "lamina propria of small intestine" in "YFP positive" | organism part, phenotype | Bulk RNA-sequencing of self-maintaining versus monocyte-replaced gut macrophages |
-1.1 | | Xk | 'ATF5 knockdown' vs 'wild type' in 'DMSO' | compound, genotype | Microarray to find ATF5 dependent genes in response to proteasome inhibition |
-1.1 | | Xk | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'wild type' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
-1.1 | | Xk | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
1.1 | | Xk | 'dexamethasome' vs 'methyl beta-clodextrin' in 'Nr1d1 homozygous knockout; 1 milligram per kilogram; ZT18' | compound, genotype, time | RNASeq data analysis of wild type and reverb alpha knockout cells from mouse liver, at different time points, with or without DEX treatment |
-1.1 | | Xk | 'doxycycline; 200 nanogram per milliliter; neoplasm; 12 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
-1.1 | | Xk | 'Cbfb+/MYH11' vs 'control of Cbfb+/MYH11' | genotype | Transcription profiling by array of Mus musculus expressing Cbfb-MYH11 |
1.1 | | Xk | 'stromal cell; E2' vs 'stromal cell; vehicle' | cell type, treatment | Affymetrix gene chip analysis for the whole mouse genome transcripts of epithelial and stromal cells from mouse uterine primary co-culture treated with either vehicle or E2 |
-1.1 | | Xk | 'interferon gamma' vs 'dexamethasone; 100 nanomolar' | compound, stimulus | RNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone |
1.1 | | Xk | 'Insm1-expressing endocrine progenitor cell' vs 'Insm1-lacking endocrine progenitor cell' in 'embryonic day 15.5' | cell type, developmental stage | Transcriptional regulation of endocrine cell differentiation by Insm1 |
-1.1 | | Xk | 'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs' | growth condition | RNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs |
1.1 | | Xk | 'co-culture' vs 'separate' in 'wild type genotype' | genotype, growth condition | RNA-seq of wild-type and transformed Ink4a/Arf-/-; EGFRvIII neural stem cells in separate or co-culture conditions |
-1.1 | | Xk | 'lipopolysaccharide; 10 nanogram per milliliter and PFI-1; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.1 | | Xk | 'dmrt1 knockout' vs 'wild type' in 'C57BL/6' | genotype, strain | Dmrt1 (doublesex and mab-3 related transcription factor 1) conditional knockout expression analysis of E15.5 testes. |
1.1 | | Xk | 'oxygen/glucose-deprivation followed by restoration of oxygen/glucose' vs 'none' in 'Ubc9 overexpression; undifferentiated' | genotype, growth condition, stimulus | SUMOylation promotes survival and integration of neural stem cell grafts in stroke |
-1 | | Xk | 'nmf205, Gcn2 double mutant' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing in cerebellum of mouse Gcn2 -/-, nmf205-/- and nmf205-/-;Gcn2-/- |
-1 | | Xk | 'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
1 | | Xk | 'Trim24,Trp53 double knockdown' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing of mouse embryonic stem cells following Trim24 and/or p53 knockdown |
-1 | | Xk | 'beta cell specific Pax6 knockout' vs 'wild type' | phenotype | RNA-Seq of pancreatic islets from beta cell-specific Pax6 knockout mice |
-1 | | Xk | 'follicle stimulating hormone and epidermal growth factor' vs '293H control medium' | growth condition | Transcription profiling by array of mouse cumulus cells after culture with growth differentiation factor 9 or follicle stimulating hormone and epidermal growth factor |
1 | | Xk | 'myelocyte' vs 'hemopoietic stem cell' | cell type | Gene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes. |
-1 | | Xk | 'Debaryomyces hansenii' at '6 hour' vs 'none' at '0 hour' | stimulus, time | RNA seq of mouse bone marrow derived macrophages treated with Debaryomyces hansenii against untreated controls |
1 | | Xk | 'normobaric hypoxia' vs 'control' | growth condition | Comparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo. |
-1 | | Xk | '2'-fucosyllactose supplementation' vs 'control' in '8 weeks post-ileocecal resection' | diet, treatment | Transcriptomic characterization of the impact of 2'-fucosyllactose supplementation on intestinal adaptation following ileocecal resection. |
1 | | Xk | 'undifferentiated' vs 'differentiated; rosiglitazone' in '129S6sv/ev' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-1 | | Xk | 'human-Mfn2 T111A/S442A-overexpressing (Mfn2AA)' vs 'tet-off control' in '5 week; left ventricle' | age, genotype, organism part | Transcription profiling by high throughput sequencing of a mitofusin 2 (Mfn2) mutant in mouse |
1 | | Xk | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'F1.129xB6' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
