ENSMUSG00000020048 (Hsp90b1)

mus musculus

heat shock protein 90, beta (Grp94), member 1

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Mus musculus
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Showing 7 experiments:
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.1688 × 10-6-5.5
Hsp90b1'diabetic pregnancy' vs 'normal'diseaseTranscription profiling by array of E10.5 embryos from diabetic pregnancies and matched controls from normal pregnancies to study the effect of maternal diabetes on transcription in the developing embryo
Adjusted p-valueLog2-fold change
3.1116 × 10-533.5
Hsp90b1'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.0787 × 10-42.6
Hsp90b1'interferon beta' vs 'none' in 'wild type; uninfected'compound, disease, genotypeTranscription profiling of mouse influenza virus infected in wild type and mutant animals revels induced gene expression changes of regional B cells are mediated in part through type I IFN
Adjusted p-valueLog2-fold change
5.0589 × 10-8-2.5
Hsp90b1'subconfluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
8.0924 × 10-8-2.4
Hsp90b1'collagen sandwich' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.1778 × 10-23-2.3
Hsp90b1'extracellular vesicle; EMT cell culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
1.9762 × 10-22.3
Hsp90b1'13 day; Alpha9 knockout' vs '13 day; wild type'age, genotypeTemporal profiling of gene expression in cochleae of wild type and alpha9 null mice
Adjusted p-valueLog2-fold change
1.4221 × 10-92.2
Hsp90b1'clear cell sarcoma; Rosa26CreER' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.9283 × 10-8-2.1
Hsp90b1'intravenous injection of 10-100 thousand B-ALL cells' vs 'none' in 'lentiviral expression of mTie2-IFN-mirT and Tie2-driven overexpression of IFNalpha'genotype, stimulusRNA-seq of mouse macrophages to investigate how interferon gene therapy reprograms the leukemia microenvironment
Adjusted p-valueLog2-fold change
7.7081 × 10-6-2
Hsp90b1'collagen sandwich' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
5.6013 × 10-3-2
Hsp90b1'Tetrafluororethane; 50000 part per million; air' vs 'none; ; air'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
8.0793 × 10-3-2
Hsp90b1'Coumarin; 200 milligram per kilogram; corn oil' vs 'none; ; corn oil'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
5.4331 × 10-711.9
Hsp90b1"tunicamycin; 2 microgram per milliliter" vs "DMSO" in "C57BL/6J x NZO/H1LtJ F1 cross"compound, strainTranscription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress
Adjusted p-valueLog2-fold change
5.3898 × 10-21-1.9
Hsp90b1'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
5.9021 × 10-7-1.9
Hsp90b1'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.2955 × 10-5-1.9
Hsp90b1'subconfluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.8686 × 10-41.9
Hsp90b1'Trypanosoma brucei STIB247' vs 'uninfected'infectTranscription profiling by array of spleens from mice infected with different Trypanosoma brucei strains
Adjusted p-valueLog2-fold change
1.6006 × 10-31.9
Hsp90b1'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '1.5 to 3 month mice'age, time, treatmentAged Mice are Unable to Mount an Effective Myeloid Response to Sepsis
Adjusted p-valueLog2-fold change
1.3108 × 10-831.8
Hsp90b1"tunicamycin; 2 microgram per milliliter" vs "DMSO" in "C57BL/6J x 129S1Sv/ImJ F1 cross"compound, strainTranscription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress
Adjusted p-valueLog2-fold change
1.5115 × 10-28-1.8
Hsp90b1'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
6.6305 × 10-19-1.8
Hsp90b1'extracellular vesicle; MET cell culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
1.2821 × 10-61.8
Hsp90b1'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal'diseaseTranscription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma
Adjusted p-valueLog2-fold change
1.6461 × 10-2-1.8
Hsp90b1'PTEN null, P53-/-' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
3.3315 × 10-21.8
Hsp90b1'influenza' vs 'uninfected' in 'wild type'compound, disease, genotypeTranscription profiling of mouse influenza virus infected in wild type and mutant animals revels induced gene expression changes of regional B cells are mediated in part through type I IFN
Adjusted p-valueLog2-fold change
4.1231 × 10-21.8
Hsp90b1'megakaryocyte' vs 'hematopoietic stem cell'cell typeTranscription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells
Adjusted p-valueLog2-fold change
1.1251 × 10-871.7
Hsp90b1"tunicamycin; 2 microgram per milliliter" vs "DMSO" in "PWK/PhJ"compound, strainTranscription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress
Adjusted p-valueLog2-fold change
3.2018 × 10-81.7
Hsp90b1'wormy, worm left; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
2.6854 × 10-7-1.7
Hsp90b1'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.6373 × 10-5-1.7
Hsp90b1'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.3958 × 10-5-1.7
Hsp90b1'fasted' vs 're-fed' in 'wild type genotype; Gabpa miRNA'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
3.7702 × 10-41.7
Hsp90b1'Insm1-expressing/Pdx1-high expressing endocrine progenitor cell' vs 'Insm1-expressing/Pdx1-low expressing endocrine progenitor cell' in 'embryonic day 18.5'cell type, developmental stageTranscriptional regulation of endocrine cell differentiation by Insm1
Adjusted p-valueLog2-fold change
1.5082 × 10-31.7
Hsp90b1'calorie restricted diet' vs 'normal diet' at '15 month'age, dietTranscription profiling by array of cochleae from mice fed a calorie-restricted diet
Adjusted p-valueLog2-fold change
1.0165 × 10-21.7
Hsp90b1'Trypanosoma brucei TREU927' vs 'uninfected'infectTranscription profiling by array of spleens from mice infected with different Trypanosoma brucei strains
Adjusted p-valueLog2-fold change
9.9905 × 10-26-1.6
Hsp90b1'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
1.1581 × 10-131.6
Hsp90b1"tunicamycin; 2 microgram per milliliter" vs "DMSO" in "C57BL/6J x WSB/EiJ F1 cross"compound, strainTranscription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress
Adjusted p-valueLog2-fold change
7.2772 × 10-7-1.6
Hsp90b1'extracellular vesicle; non-stimulated culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
8.0941 × 10-61.6
Hsp90b1'dominant-negative Brg1' vs 'wild type'genotypeTranscription profiling by array of lens tissue from mice expressing a dnBrg1 transgenic construct
Adjusted p-valueLog2-fold change
1.2486 × 10-41.6
Hsp90b1'500 micromolar palmitate' vs '1 volume percent bovine serum albumin'compoundTranscription profiling of mouse C2C12 myotubes treated overnight with 500 uM palmitate or 1% bovine serum albumin control to identify mediators of obesity-linked reductions in PGC-1
Adjusted p-valueLog2-fold change
1.4015 × 10-21.6
Hsp90b1'5 day; Ad-VEGF-A164' vs '0 day; control'time, treatmentTranscription profiling by array of stromal-based signatures for the classification of gastric cance
Adjusted p-valueLog2-fold change
2.0482 × 10-2-1.6
Hsp90b1'Malathion; 14800 part per million; rodent chow' vs 'none; ; rodent chow'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
2.6872 × 10-2-1.6
Hsp90b1'1,2-Dibromoethane; 62 milligram per kilogram; corn oil' vs 'none; ; corn oil'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
3.3525 × 10-2-1.6
Hsp90b1'16 week' vs '4 week'ageDifferential gene expression in the Lacrimal gland during development and onset of xerostomia in Sjogren's syndrome-like disease of the C57BL/6.NOD-Aec1Aec2 mouse.
Adjusted p-valueLog2-fold change
3.8456 × 10-21.6
Hsp90b1'synovial sarcoma' vs 'normal'diseaseTranscription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice
Adjusted p-valueLog2-fold change
7.1368 × 10-321.5
Hsp90b1'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'TRAIL homozygous knock out'genotype, infectComparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice
Adjusted p-valueLog2-fold change
7.925 × 10-131.5
Hsp90b1'Lymphocytic choriomeningitis mammarenavirus' vs 'none' in 'wild type genotype'genotype, infectComparison of Trail+/+ versus Trail-/- splenic NK cells from naïve and LCMV-infected mice
Adjusted p-valueLog2-fold change
1.1688 × 10-12-1.5
Hsp90b1'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
1.3654 × 10-71.5
Hsp90b1'CCl4; 1.6 gram per kilogram' at '8 hour' vs 'none' at '0 hour'compound, timeTranscriptional responses in liver upon acute CCl4 intoxication
Adjusted p-valueLog2-fold change
1.1188 × 10-61.5
Hsp90b1"tunicamycin; 2 microgram per milliliter" vs "DMSO" in "A/J"compound, strainTranscription profiling by high throughput sequencing of mouse embryonic fibroblasts treated with tunicamycin to study the transcriptional response to endoplasmic reticulum stress
Adjusted p-valueLog2-fold change
1.4235 × 10-5-1.5
Hsp90b1'granulocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
3.8331 × 10-3-1.5
Hsp90b1'normal skin; PKC alpha-/-' vs 'normal skin; wild type genotype'clinical history, genotypeAltered dermal architecture in PKCα-/- skin
Adjusted p-valueLog2-fold change
1.2381 × 10-2-1.5
Hsp90b1'PTEN null' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
2.849 × 10-21.5
Hsp90b1'2,3-Benzofuran; 240 milligram per kilogram; corn oil' vs 'none; ; corn oil'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
2.7362 × 10-1921.4
Hsp90b1'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout'compound, genotypeCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Adjusted p-valueLog2-fold change
4.0264 × 10-261.4
Hsp90b1'α-GalCer; 2 microgram' vs 'none' in 'wild type genotype'compound, genotypeCD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells
Adjusted p-valueLog2-fold change
7.1067 × 10-61.4
Hsp90b1'7 days P. chabaudi infected' vs 'uninfected' in 'intact male'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
9.9739 × 10-6-1.4
Hsp90b1'fasted' vs 're-fed' in 'wild type genotype; control miRNA'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
1.117 × 10-5-1.3
Hsp90b1'collagen sandwich' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
4.044 × 10-5-1.3
Hsp90b1'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
1.6091 × 10-41.3
Hsp90b1'Kit ligand' vs 'none' in 'wasp knockout'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
3.0934 × 10-41.3
Hsp90b1'induce erythroid differentiation' vs 'none' in 'wild type'genotype, stimulusTranscription profiling by array of Mouse erythro-leukaemia cells during differentiation to investigate the influence of Runx1 transcription factor
Adjusted p-valueLog2-fold change
6.0847 × 10-4-1.3
Hsp90b1'normobaric hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo.
Adjusted p-valueLog2-fold change
6.738 × 10-41.3
Hsp90b1'wormy, worm separated; Trichuris muris' vs 'control; non wormy' in 'caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
6.7831 × 10-4-1.3
Hsp90b1'collagen sandwich' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.4079 × 10-3-1.3
Hsp90b1'fasted' vs 're-fed' in 'db/db; control miRNA'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
7.953 × 10-92-1.2
Hsp90b1'SMRT shRNA; CpG; 6 hour' vs 'none; none; 0 hour'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
2.0558 × 10-83-1.2
Hsp90b1'CpG; 6 hour' vs 'none; 0 hour' in 'SMRT shRNA'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
2.0517 × 10-121.2
Hsp90b1'Id2_Id3_double knockout' vs 'wild type' in 'CD4+TCRb+CD8– cell; thymus'cell type, genotype, organism partTranscription profiling by high throughput sequencing of Id-proteins (Id2 and Id3) gene knockout cells
Adjusted p-valueLog2-fold change
2.1278 × 10-71.2
Hsp90b1'Kit ligand' vs 'none' in 'wild type'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
2.5602 × 10-61.2
Hsp90b1'7 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized female'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
5.2159 × 10-61.2
Hsp90b1'Mycobacterium tuberculosis; C57BL/6J; 30 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
2.2038 × 10-51.2
Hsp90b1'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
3.4055 × 10-51.2
Hsp90b1'30 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
7.6812 × 10-51.2
Hsp90b1'14 days P. chabaudi infected' vs 'uninfected' in 'intact female'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
1.1532 × 10-41.2
Hsp90b1'missense mutation (T2996C) in Mucin 2 (Muc2)' vs 'wild type genotype'genotypeTranscription profiling of mouse intestine in ENU mutagenesis mouse strains with missense mutations in Muc2 mucin and ER stress
Adjusted p-valueLog2-fold change
2.1165 × 10-41.2
Hsp90b1'chronic pancreatitis' vs 'control'diseasePancreatic gene expression associated with cerulein induced chronic pancreatitis in mice
Adjusted p-valueLog2-fold change
2.2864 × 10-41.2
Hsp90b1'Trichuris muris' vs 'control' in 'non wormy; caecum'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
3.0003 × 10-4-1.2
Hsp90b1'confluent monolayer on collagen' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
3.9653 × 10-4-1.2
Hsp90b1'fasted' vs 're-fed' in 'db/db; Gabpa miRNA'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
1.4969 × 10-31.2
Hsp90b1'Kin-' vs 'wild type' in 'cAMP' at '24 hour'compound, genotype, timeTranscription profiling by array of mouse S49 cells mutant for Kin after treatment with cAMP
Adjusted p-valueLog2-fold change
2.7382 × 10-2-1.2
Hsp90b1'Runx3 knockout' vs 'wild type genotype' in 'IL-2'compound, genotypeRunx3 function in splenic NK cells (IL-2 or IL-15)
Adjusted p-valueLog2-fold change
3.4378 × 10-12-1.1
Hsp90b1'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
7.3357 × 10-91.1
Hsp90b1'Trichuris muris' vs 'control' in 'mesenteric lymph node'environmental stress, infect, organism partRNA-seq of mouse intestinal mucosa to investigate infection by the parasitic nematode Trichuris muris
Adjusted p-valueLog2-fold change
7.8592 × 10-61.1
Hsp90b1'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
1.9003 × 10-51.1
Hsp90b1'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.7759 × 10-5-1.1
Hsp90b1'5-azacytidine 10 micromolar' vs 'none'compoundTranscription profiling by array of mouse C2C12 cells treated with 5-azacytidine
Adjusted p-valueLog2-fold change
5.4441 × 10-51.1
Hsp90b1'Cbfb knockout' vs 'control of Cbfb knockout'genotypeTranscription profiling by array of Mus musculus expressing Cbfb-MYH11
Adjusted p-valueLog2-fold change
6.3163 × 10-51.1
Hsp90b1'miR-1-133a_FGFR1_tKO' vs 'miR-1-133a_dKO'compound, genotypeRepression of OSMR and FGFR1 by miR-1/133a prevents adult cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
Adjusted p-valueLog2-fold change
2.6012 × 10-41.1
Hsp90b1'mutant MyoD expression' at '24 hour' vs 'wild type MyoD expression' at '0 hour'phenotype, timeTranscription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation.
Adjusted p-valueLog2-fold change
2.8143 × 10-41.1
Hsp90b1'CCl4; 1.6 gram per kilogram' at '24 hour' vs 'none' at '0 hour'compound, timeTranscriptional responses in liver upon acute CCl4 intoxication
Adjusted p-valueLog2-fold change
3.7861 × 10-4-1.1
Hsp90b1'RAD001' vs 'placebo' in 'wild type' at '48 hour'compound, genotype, timeTranscription profiling by array of prostate from AKT transgenic mice treated with RAD001.
Adjusted p-valueLog2-fold change
6.7376 × 10-41.1
Hsp90b1'Mycobacterium tuberculosis; DBA/2J congenic; 70 day' vs 'control; DBA/2J congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
2.7703 × 10-3-1.1
Hsp90b1'subarachnoid hemorrhage' vs 'normal'diseaseTranscription profiling by array of the effect of SAH on brain cells in white matter region of mice
Adjusted p-valueLog2-fold change
2.8343 × 10-31.1
Hsp90b1'mutant MyoD expression' at '12 hour' vs 'wild type MyoD expression' at '0 hour'phenotype, timeTranscription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation.
Adjusted p-valueLog2-fold change
1.0489 × 10-21.1
Hsp90b1'Was knockout' vs 'wild type genotype'genotypeGerminal Center B-Cell gene expression comparison between Wiskott-Aldrich syndrome protein KO mice and WT mice
Adjusted p-valueLog2-fold change
9.133 × 10-16-1
Hsp90b1'pabpn1l -/-' vs 'wild type genotype' in 'zygote'genotype, organism partRNA-seq of oocytes and zygotes from pabpn1l ko and wt female mice
Adjusted p-valueLog2-fold change
1.0511 × 10-15-1
Hsp90b1'LDB1 knock-down with full-length Ldb1 construct' vs 'control shRNA'RNA interferenceRole of LDB1 in the transition from chromatin looping to transcription activation
Adjusted p-valueLog2-fold change
5.521 × 10-13-1
Hsp90b1'MyD88 homozygous knockout' vs 'wild type genotype' in 'TLR9 ligand CpG ODN (1826)'genotype, stimulusTranscription profiling by sequencing of murine MyD88 -/- and MyD88 +/+ mTECs stimulated with a TLR9 ligand
Adjusted p-valueLog2-fold change
1.5541 × 10-8-1
Hsp90b1'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.7858 × 10-8-1
Hsp90b1'liver-specific Cnot1 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
3.3819 × 10-61
Hsp90b1'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector'genotypeRNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice
Adjusted p-valueLog2-fold change
4.539 × 10-61
Hsp90b1'14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized female'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
2.2494 × 10-5-1
Hsp90b1'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'Cstb knockout'genotype, growth condition, timeTranscriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation
Adjusted p-valueLog2-fold change
2.4899 × 10-41
Hsp90b1'7 days P. chabaudi infected' vs 'uninfected' in 'intact female'clinical information, disease, sex, timeTranscription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids
Adjusted p-valueLog2-fold change
3.2825 × 10-4-1
Hsp90b1'confluent monolayer on collagen' at '5 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
8.6349 × 10-4-1
Hsp90b1'db/db' vs 'wild type genotype' in 'Gabpa miRNA; re-fed'RNA interference, diet, genotypeGene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter
Adjusted p-valueLog2-fold change
1.1439 × 10-31
Hsp90b1'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
2.2695 × 10-31
Hsp90b1'promyelocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
2.8658 × 10-31
Hsp90b1'Tet2 knockout' vs 'wild type' in 'hematopoietic stem cell'cell type, genotypeTranscription profiling by high throughput sequencing of bone marrow stem and progenitor cells from Tet2 depleted mice
Adjusted p-valueLog2-fold change
3.8757 × 10-31
Hsp90b1'recombinant human interleukin-2; 100 unit per milliliter; 12 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2
Adjusted p-valueLog2-fold change
5.8823 × 10-3-1
Hsp90b1'B4053; RML infected' at '6 week' vs 'B4053; uninfected' at '6 week'strain, time, treatmentTranscription profiling of mouse brain infected with prions in eight mouse-prion strain combinations in a systems approach to the study of prion disease
Adjusted p-valueLog2-fold change
2.288 × 10-21
Hsp90b1'bronchoalveolar adenocarcinoma induced using doxycycline' vs 'normal'diseaseTranscription profiling by array of lung alveolar type II epithelial cells with bronchoalveolar adenocarcinoma
Adjusted p-valueLog2-fold change
4.7038 × 10-21
Hsp90b1'Staphylococcus aureus Sanger476; 2 hour' vs 'none; 0 hour' in 'BALB/cByJ'infect, strain, timeGene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans