ENSMUSG00000022435 (Upk3a)

mus musculus

uroplakin 3A

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Mus musculus
Organism part
Showing 24 experiments:
Created with Highcharts 6.2.0adrenal glandbronchuscorpora quadrigeminaepididymisintestinal mucosalungmuscle tissuepancreasspleenthymusvesicular glandaxillary lymph nodecerebellumdiencephalonheartlateral nasal prominencemedial nasal prominenceolfactory epitheliumprostate glandsubmandibular glandurinary bladderzone of skin
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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9
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6
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Mammalian Kaessmann
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - adult
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2
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - CastEiJ
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Mernberger et al 2019 - Organism Part
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Vertebrates
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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4
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14 - embryonic day 10.5
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4 Bonthuis et al - Idaho derived wild …
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4 Bonthuis et al - C57BL/6J
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Proteomics
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Transcriptomics
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-8.5
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
1.3249 × 10-13-8.5
Upk3a'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
1.4419 × 10-7-3
Upk3a'chronic cystitis' vs 'none' in 'C57/Bl6'disease, strainChronic cystitis microarray comparing C3H/HeN and C57BL/6 bladder gene expression
Adjusted p-valueLog2-fold change
2.2342 × 10-22.8
Upk3a'Sod1G86R' vs 'wild type genotype' in '105 day; callosal sulcus'age, genotype, organism partRNA sequencing of corticospinal neurons and control callosal projection neurons purified from the cerebral cortex of adult wild-type and Sod1G86R mice, a model of amyotrophic lateral sclerosis, at four disease-relevant ages.
Adjusted p-valueLog2-fold change
2.5538 × 10-5-2.6
Upk3a'reduced expression of miR-25' vs 'wild type'phenotypeTranscription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice
Adjusted p-valueLog2-fold change
1.2114 × 10-22.6
Upk3a'extracellular vesicle; non-stimulated culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
3.2034 × 10-11-2.5
Upk3a'Abcc8-/-' vs 'wild type genotype' in 'normal; male'diet, genotype, sexEffects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome
Adjusted p-valueLog2-fold change
1.8527 × 10-3-2.3
Upk3a'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week'age, genotypePrevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA
Adjusted p-valueLog2-fold change
1.7289 × 10-22.3
Upk3a'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'inguinal fat pad'organism part, phenotypeRNA-seq to identify the role of mRNA decay in mouse adipose tissues
Adjusted p-valueLog2-fold change
9.8296 × 10-9-2.1
Upk3a'Abcc8-/-' vs 'wild type genotype' in 'high fat; female'diet, genotype, sexEffects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome
Adjusted p-valueLog2-fold change
2.2131 × 10-8-2.1
Upk3a'Abcc8-/-' vs 'wild type genotype' in 'normal; female'diet, genotype, sexEffects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome
Adjusted p-valueLog2-fold change
1.9604 × 10-22
Upk3a'p150 subunit of CAF-1 siRNA knockdown' vs 'scrambled siRNA'RNA interferenceRNA-seq of control siRNA, p150 siRNA and p60 siRNA transfected mES cells
Adjusted p-valueLog2-fold change
2.1787 × 10-2-2
Upk3a'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'A/J'infect, strain, timeGenomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression
Adjusted p-valueLog2-fold change
8.9518 × 10-41.9
Upk3a'Smad4f/f x CCSPicrePtenf/f' vs 'wild type' at '7 month'age, genotypeErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis [expression]
Adjusted p-valueLog2-fold change
1.074 × 10-21.9
Upk3a'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
2.6065 × 10-4-1.8
Upk3a'STAT1 -/-' vs 'wild type genotype' in 'SARS coronavirus MA15' at '9 day'genotype, infect, timeTranscriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds
Adjusted p-valueLog2-fold change
3.8968 × 10-41.8
Upk3a'Ptenf/f x CCSPiCre' vs 'wild type' at '7 month'age, genotypeErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis [expression]
Adjusted p-valueLog2-fold change
1.4626 × 10-3-1.8
Upk3a'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2'genotype, irradiateRNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy
Adjusted p-valueLog2-fold change
1.2578 × 10-5-1.6
Upk3a'Abcc8-/-' vs 'wild type genotype' in 'high fat; male'diet, genotype, sexEffects of increased intracellular calcium and overnutrition on pancreatic beta cell transcriptome
Adjusted p-valueLog2-fold change
3.0668 × 10-31.6
Upk3a'wild type; mature luminal' vs 'wild type; MaSC/basal'cell type, genotypeExpression data from sorted control and Pygo2-null mouse mammary stem/basal cells
Adjusted p-valueLog2-fold change
1.0639 × 10-51.5
Upk3a'SARS coronavirus MA15' vs 'none' in 'wild type genotype' at '7 day'genotype, infect, timeSM020 - Infection with SARS MA15 of C57BL/6J mice and KEPI (ppp1r14c) knockouts
Adjusted p-valueLog2-fold change
1.4445 × 10-4-1.5
Upk3a'SARS coronavirus MA15' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
7.887 × 10-41.4
Upk3a'Pygo2 SS knockout; MaSC/basal' vs 'wild type; MaSC/basal'cell type, genotypeExpression data from sorted control and Pygo2-null mouse mammary stem/basal cells
Adjusted p-valueLog2-fold change
1.0193 × 10-31.3
Upk3a'Smad4f/f x CCSPicrePtenf/f' vs 'wild type' at '12 month'age, genotypeErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis [expression]
Adjusted p-valueLog2-fold change
4.5047 × 10-31.3
Upk3a'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
6.1955 × 10-3-1.3
Upk3a'STAT1 -/-' vs 'wild type genotype' in 'SARS coronavirus MA15' at '5 day'genotype, infect, timeTranscriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds
Adjusted p-valueLog2-fold change
1.8241 × 10-2-1.3
Upk3a'gamma radiation; 8 Gray' vs 'none' in 'Lgr5-Cre-ERT2; Il22-/-'genotype, irradiateRNA Seq of colonic Lgr5+ epithelial stem cells in Il22+/+ and Il22-/- mice during homeostasis and 24h after irradiation with 8 Gy
Adjusted p-valueLog2-fold change
4.881 × 10-61.2
Upk3a'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '7 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
7.0577 × 10-41.2
Upk3a'Stat5a (Stat5abnull/Stat5b-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
4.6225 × 10-3-1.2
Upk3a'Hnf1a knock out' vs 'wild type'genotypeTranscription profiling of pancreatic islets from Hnf1a-deficient and wild type mice
Adjusted p-valueLog2-fold change
3.3619 × 10-4-1.1
Upk3a'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '2 day'stimulus, timeSM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection.
Adjusted p-valueLog2-fold change
3.3991 × 10-3-1.1
Upk3a'SARS coronavirus MA15 E protein mutant Δ3' vs 'mock'infectHost responses contributing to the attenuation of severe acute respiratory syndrome coronaviruses missing E protein domains
Adjusted p-valueLog2-fold change
1.3688 × 10-21.1
Upk3a'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
1.6373 × 10-8-1
Upk3a'trans-tympanically injected with Hemophilus influenza' vs 'control'treatmentOtitis Media Impact on Middle Ear
Adjusted p-valueLog2-fold change
6.3958 × 10-8-1
Upk3a'SARS coronavirus MA15' vs 'mock' in 'wild type genotype' at '2 day'genotype, infect, timeMouse lung tissue transcriptome response to a mouse-adapted strain of SARS-CoV in wild type C57BL6/NJ mice and TLR3-/- mice
Adjusted p-valueLog2-fold change
7.1546 × 10-7-1
Upk3a'AMPK double knockout; floxed AMPK alpha 1 and 2 with Ins1-Cre' vs 'floxed AMPK without Ins1-Cre; wild type'genotype, phenotypeTranscription profiling by high throughput sequencing of pancreatic islets from LKB1 and AMPK knockout mice
Adjusted p-valueLog2-fold change
2.8262 × 10-51
Upk3a'Influenza A virus' vs 'mock' in 'interleukin-22'infect, stimulusTranscription profiling by array of pulmonary gene expression in response to interleukin-22 during severe influenza
Adjusted p-valueLog2-fold change
1.4385 × 10-31
Upk3a'active Sendai virus' vs 'UV-inactivated Sendai virus' at '21 day' on 'Affymetrix MOE430A Array'infect, timeTranscription profiling by array of lungs from C57BL/6J mice infected with Sendai virus
Adjusted p-valueLog2-fold change
2.6066 × 10-3-1
Upk3a'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5'cell type, developmental stageTranscription profiling by high throughput sequencing of murine beta cells at key stages of maturation
Adjusted p-valueLog2-fold change
3.4816 × 10-2-1
Upk3a'IFNAR1 -/-' vs 'wild type genotype' in 'SARS coronavirus MA15' at '5 day'genotype, infect, timeTranscriptomic analysis of host response to mouse-adapted SARS virus in wild type, STAT1 -/-, and IFNAR1 -/- mouse genetic backgrounds