ENSMUSG00000023977 (Ubr2)

mus musculus

ubiquitin protein ligase E3 component n-recognin 2

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Mus musculus
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Showing 7 experiments:
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T
Mammalian Kaessmann
T
9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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9 in 3 strains - C57BL/6
T
9
T
3 Soumillon et al
T
14 - embryonic day 10.5
P
Proteomics
T
Transcriptomics
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-2.1
1
3.4
Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
2.46 × 10-33.4
Ubr2'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.0093 × 10-4-2.1
Ubr2'recombinant human interleukin-2; 100 unit per milliliter; 6 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2
Adjusted p-valueLog2-fold change
6.8991 × 10-11-2
Ubr2'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
4.9265 × 10-2-2
Ubr2'insulin-like growth factor-1' vs 'none'compoundGene expression profiling of murine T regulatory cells after insulin-like growth factor-1 stimulation
Adjusted p-valueLog2-fold change
2.3452 × 10-20-1.8
Ubr2'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
3.0879 × 10-71.7
Ubr2'TUT4 deficiency; TUT7 knockout' vs 'wild type'phenotypeMicroarray profiling of mouse pachytene cells deficient for UPF2 or both TUT4 and TUT7
Adjusted p-valueLog2-fold change
5.7518 × 10-6-1.5
Ubr2'collagen sandwich' at '1 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
6.7309 × 10-5-1.5
Ubr2'recombinant human interleukin-2; 100 unit per milliliter; 4 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2
Adjusted p-valueLog2-fold change
1.5328 × 10-3-1.5
Ubr2'recombinant human interleukin-2; 100 unit per milliliter; 2 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2
Adjusted p-valueLog2-fold change
6.3286 × 10-111.4
Ubr2'upf3 knockout' vs 'wild type' in 'testis'cell type, genotypeUPF2 establishes testis-specific transcriptome enriched in transcripts with shorter 3’UTRs
Adjusted p-valueLog2-fold change
5.8114 × 10-6-1.4
Ubr2'CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
1.7074 × 10-51.4
Ubr2'TUT4; TUT7 double knockout' vs 'wild type'phenotypeMicroarray profiling of mouse pachytene cells deficient for UPF2 or both TUT4 and TUT7
Adjusted p-valueLog2-fold change
3.3878 × 10-5-1.4
Ubr2'normobaric hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to normobaric hypoxia in vivo.
Adjusted p-valueLog2-fold change
3.9179 × 10-4-1.4
Ubr2'recombinant human interleukin-2; 100 unit per milliliter; 8 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2
Adjusted p-valueLog2-fold change
1.735 × 10-14-1.3
Ubr2'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.5289 × 10-7-1.3
Ubr2'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.2591 × 10-6-1.3
Ubr2'Kit ligand' vs 'none' in 'wasp knockout'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
7.969 × 10-51.3
Ubr2'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
2.075 × 10-4-1.3
Ubr2'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
5.3238 × 10-71.2
Ubr2'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'neutrophil'cell type, genotypeRNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice
Adjusted p-valueLog2-fold change
1.1227 × 10-6-1.2
Ubr2'hypoxia' vs 'control'treatmentTranscription profiling of mouse Jardine SIDS Model
Adjusted p-valueLog2-fold change
7.4329 × 10-6-1.2
Ubr2'subconfluent monolayer on collagen' at '2 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
1.4742 × 10-5-1.2
Ubr2'clear cell sarcoma; Rosa26CreER' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
2.7008 × 10-3-1.2
Ubr2'control mice [Gp130f/f]; cecal ligation and puncture' vs 'control mice [Gp130f/f]; control'genotype, treatmentHepatic acute phase proteins control innate immune responses during infection by promoting myeloid derived suppressor cell function
Adjusted p-valueLog2-fold change
9.8761 × 10-69-1.1
Ubr2'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
3.5865 × 10-7-1.1
Ubr2'carcinoma' vs 'normal'diseaseGene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse
Adjusted p-valueLog2-fold change
1.3 × 10-5-1.1
Ubr2'antibiotics, CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
3.4565 × 10-5-1.1
Ubr2'subconfluent monolayer on collagen' at '3 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
7.0402 × 10-51.1
Ubr2'myelocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
3.3694 × 10-4-1.1
Ubr2'missense mutation (T2996C) in Mucin 2 (Muc2)' vs 'wild type genotype'genotypeTranscription profiling of mouse intestine in ENU mutagenesis mouse strains with missense mutations in Muc2 mucin and ER stress
Adjusted p-valueLog2-fold change
4.7266 × 10-4-1.1
Ubr2'Yersinia pestis' vs 'control' in 'neutrophil'cell type, infect, sampling siteSpatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague
Adjusted p-valueLog2-fold change
1.2474 × 10-2-1.1
Ubr2'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
5.565 × 10-71
Ubr2'extracellular vesicle; non-stimulated culture medium' vs 'none'sampling site, stimulusCellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET
Adjusted p-valueLog2-fold change
6.2055 × 10-7-1
Ubr2'Kit ligand' vs 'none' in 'wild type'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
2.97 × 10-6-1
Ubr2'Mycobacterium tuberculosis; C57BL/6J; 70 day' vs 'control; C57BL/6J; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
4.6561 × 10-6-1
Ubr2'Kit ligand; wasp knockout' vs 'Kit ligand; wild type'compound, genotypeTranscription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand
Adjusted p-valueLog2-fold change
2.9818 × 10-5-1
Ubr2'30 days of tuberculosis' vs 'uninfected'disease, timeTranscription profiling by array of lungs from mice infected with tuberculosis
Adjusted p-valueLog2-fold change
4.4636 × 10-51
Ubr2'5 nanogram per milliliter; TGFbeta1' vs 'none' at '24 hour'compound, timeTranscription profiling by array of mouse hepatocytes following treatment with growth factor beta 1 in a time series
Adjusted p-valueLog2-fold change
8.9934 × 10-4-1
Ubr2'polarized with E coli lipopolysacharide and INF-gamma' vs 'untreated'compound, treatmentExpression data from polarized macrophages: effect of p53
Adjusted p-valueLog2-fold change
2.7643 × 10-3-1
Ubr2'recombinant human interleukin-2; 100 unit per milliliter; 10 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2
Adjusted p-valueLog2-fold change
3.522 × 10-3-1
Ubr2'recombinant human interleukin-2; 100 unit per milliliter; 12 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2
Synonym
9930021A08Rik, ENSMUSG00000043296, E130209G04Rik
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
5164223, 4786162, 5490975, 17345613, 4802052, 4881355, 4853806, 5039695, 5513184, 4478043, 5051387, 5484729, 5344995, 5301508, 5342013, 4321422, 4699038, 4992664, 5511288, 4587208, 4674494, 1427163_at, 4995935, A_55_P2008576, 4491564, 4555879, 4987811, 5010405, 5243364, 5547888, A_55_P2122588, 5333662, 5275095, ILMN_1237752, 5574166, 4306194, 4866196, 1429515_at, 5183845, 5329807, 4979239, ILMN_1235729, 4659801, 4951008, 4500152, 4570782, 4864088, 4955491, A_51_P513611, 4900547, 5326826, 1429516_at, 111342_at, 4894616, 5237953, 4379548, 5595805, 5091382, 4540173, 5359023, 5504442, 5228550, 5233358, 5329617, 4934437, 10451495, 4453928, 4423431, 4943855, A_51_P250788, A_52_P459750, 5168692, 5394737, 5364273, 5582595, 4369023, A_52_P387502, 4697786, 4994671, 111993_at, 5402976, 5428625, A_51_P144575, 4617423, 5005150
Reactome pathway ID