-4.3 | | Phf1 | 'Yersinia pestis' vs 'control' in 'neutrophil' | cell type, infect, sampling site | Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague |
-4.2 | | Phf1 | 'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
3 | | Phf1 | 'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-' | cell type, phenotype | Thymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche. |
2.9 | | Phf1 | 'granulocyte' vs 'hemopoietic stem cell' | cell type | Gene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes. |
-2.5 | | Phf1 | 'LDB1 knock-down with full-length Ldb1 construct' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
2.4 | | Phf1 | 'AZD5069; 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
-2.3 | | Phf1 | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
-2.2 | | Phf1 | 'Cd1d homozyous knockout' vs 'wild type genotype' in 'α-GalCer; 2 microgram' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
-2.1 | | Phf1 | 'α-GalCer; 2 microgram' vs 'none' in 'wild type genotype' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
-2.1 | | Phf1 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-2.1 | | Phf1 | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.7 | | Phf1 | 'reduced expression of miR-25' vs 'wild type' | phenotype | Transcription profiling by high throughput sequencing of wild type and miR-25 agomir or antagomir treated mice |
-1.7 | | Phf1 | 'Kit ligand' vs 'none' in 'wasp knockout' | compound, genotype | Transcription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand |
1.7 | | Phf1 | 'hematopoietic stem cell and hematopoietic multipotent progenitor cell' vs 'common myeloid progenitor' | cell type | Transcription profiling by high throughput sequencing between multipotent hematopoietic stem progenitor cells LS+K) and myeloid committed cells (LS−K) of the mouse bone marrow |
-1.6 | | Phf1 | '21 percent oxygen, 37 degree Celsius, 10 percent serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
1.6 | | Phf1 | 'myelocyte' vs 'hemopoietic stem cell' | cell type | Gene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes. |
-1.6 | | Phf1 | 'interferon beta' vs 'none' in 'wild type; uninfected' | compound, disease, genotype | Transcription profiling of mouse influenza virus infected in wild type and mutant animals revels induced gene expression changes of regional B cells are mediated in part through type I IFN |
1.5 | | Phf1 | 'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
1.5 | | Phf1 | '3D culture' vs '2D culture' | growth condition | mRNA-seq of mouse salivary gland cancer cells cultured in adherent or non-adherent culture |
-1.5 | | Phf1 | 'epithelium-specific Apc knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
-1.5 | | Phf1 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
1.4 | | Phf1 | 'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-1.4 | | Phf1 | '3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
-1.4 | | Phf1 | 'Kit ligand; wasp knockout' vs 'Kit ligand; wild type' | compound, genotype | Transcription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand |
1.4 | | Phf1 | 'postnatal >1 year; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
-1.4 | | Phf1 | 'Trypanosoma brucei STIB247' vs 'uninfected' | infect | Transcription profiling by array of spleens from mice infected with different Trypanosoma brucei strains |
-1.4 | | Phf1 | 'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant' | disease, stimulus | RNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice |
1.4 | | Phf1 | 'CD47 knockdown; cell from embryoid body-like cluster’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
-1.4 | | Phf1 | 'SOD1-G93A transgenic' vs 'wild type' at 'day 65' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
1.3 | | Phf1 | 'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
-1.3 | | Phf1 | '21 percent oxygen, 37 degree Celsius, no serum' vs 'none' | growth condition | RNA sequencing of native and ex vivo cultured murine tail tendon fascicles |
1.3 | | Phf1 | 'chemical hypoxia' vs 'control' | growth condition | Comparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo. |
1.3 | | Phf1 | 'extracellular vesicle; non-stimulated culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-1.3 | | Phf1 | 'AhCre Apc Floxed Cited1 knockout' vs 'control' | genotype | Cited-1 deficiency suppresses intestinal tumorigenesis through the repression of the Wnt pathway- evidence for the just right model of Wnt mediated tumorigenesis |
1.3 | | Phf1 | 'Tfc knockout; normal' vs 'control' | disease, genotype | Gene expression in thymi of Tcf1 -/-, Tcf +/- or Tcf1 -/- mice with tumor. |
1.2 | | Phf1 | 'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
1.2 | | Phf1 | '12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
1.2 | | Phf1 | 'alpha-amanitin; maternal Ring1-Rnf+' vs 'none; maternal Ring1-Rnf+' | compound, genotype | Polycomb function during oogenesis is required for mouse early embryonic development (2-cell embryos) |
-1.2 | | Phf1 | 'smoke; 3000 microgram' vs 'control; 0 microgram' in 'wild type' at 'after 5 month exposure and 1 day post-exposure' | compound, genotype, sampling time point | Transcription profiling by array of Nrf2 knockout mice exposed to cigarette smoke |
-1.2 | | Phf1 | 'SARS coronavirus MA15' vs 'none' at '4 day' | infect, time | SM014 - SARS MA15 wild type, and SARS nsp16 mutant virus infections of C57BL6 mice - A time course |
1.2 | | Phf1 | 'Col1a1-tetO-MLL/ENL' vs 'wild type' in 'hematopoietic stem cell' | cell type, genotype | Transcription profiling by high throughput sequencing of hematopoietic stem cells from a conditional-inducible mouse model of the MLL-ENL fusion oncogene |
-1.1 | | Phf1 | 'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
-1.1 | | Phf1 | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
-1.1 | | Phf1 | 'epithelium-specific mutant beta-catenin expression' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
-1.1 | | Phf1 | 'epithelium-specific Apc; Bcl9; Bcl9l knockout' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
-1.1 | | Phf1 | '14 days P. chabaudi infected' vs 'uninfected' in 'gonadectomized male' | clinical information, disease, sex, time | Transcription profiling by array of mice infected with Plasmodium chabaudi after gonadectomization to investigate involvement of gonadal steroids |
-1.1 | | Phf1 | 'glioblastoma multiforme' vs 'normal' | disease | Analysis of the expression profiles of glioma-associated microglia/macrophages and naive control cells in Mus musculus. |
1.1 | | Phf1 | 'Setd5 homozygous (null) knockout' vs 'Setd5 heterozygous knockout' | genotype | Transcriptional profiling of Setd5 heterozygous and knockout mouse embryonic stem cells |
-1.1 | | Phf1 | 'LDB1 knock-down' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
-1.1 | | Phf1 | 'SARS coronavirus MA15 dORF6' vs 'none' at '4 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
-1.1 | | Phf1 | 'Trypanosoma brucei TREU927' vs 'uninfected' | infect | Transcription profiling by array of spleens from mice infected with different Trypanosoma brucei strains |
1.1 | | Phf1 | '50 micromolar; hydrogen peroxide' vs 'none' | compound | Transcription profiling by array of mouse dermal fibroblasts after treatment with hydrogen peroxide |
-1.1 | | Phf1 | 'neoplasm' vs 'normal tissue adjacent to neoplasm' | sampling site | Transcription profiling by array of Apc+/Delta716 mouse intestinal polyps vs normal intestinal mucosa |
-1.1 | | Phf1 | 'Elk knockout; stimulated with plate-bound alphaCD3 for 30 min' vs 'wild type; stimulated with plate-bound alphaCD3 for 30 min' | genotype, stimulus | Gene expression analysis of double positive T cells from different genotypes, unstimulated or stimulated with plate-bound alphaCD3 for 30 min |
-1.1 | | Phf1 | 'AhCre Apc Floxed' vs 'control' | genotype | Cited-1 deficiency suppresses intestinal tumorigenesis through the repression of the Wnt pathway- evidence for the just right model of Wnt mediated tumorigenesis |
-1 | | Phf1 | 'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line' | cell type, genotype, growth condition | Transcription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes |
-1 | | Phf1 | 'pabpn1l -/-' vs 'wild type genotype' in 'zygote' | genotype, organism part | RNA-seq of oocytes and zygotes from pabpn1l ko and wt female mice |
-1 | | Phf1 | 'Kit ligand' vs 'none' in 'wild type' | compound, genotype | Transcription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand |
-1 | | Phf1 | 'upf3 knockout' vs 'wild type' in 'testis' | cell type, genotype | UPF2 establishes testis-specific transcriptome enriched in transcripts with shorter 3’UTRs |
-1 | | Phf1 | 'wild type genotype; SARS MA15; 4 day' vs 'wild type genotype; mock' | genotype, infect, time | SARS infection of C57BL6, and PLAT knock-out mice |
-1 | | Phf1 | 'AAV9-Ccnt1;Myh6-cre;LSL-R26CAG-c-MycERT2/+' vs 'AAV9-Ccnt1;LSL-R26CAG-c-MycERT2/+' | genotype | RNA-seq of purified cardiomocytes from adult mice (+/- AAV-CCNT1) 4 hours post MycER activation compared controls. |
-1 | | Phf1 | 'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'neutrophil' | cell type, genotype | RNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice |
-1 | | Phf1 | 'SARS coronavirus MA15; 10^5 PFU' vs 'none' at '4 day' | stimulus, time | SM001: SARS CoV MA15 infection of C57Bl/6 mouse model – Data from 4 viral doses at 1, 2, 4 and 7 days post infection. |
1 | | Phf1 | 'postnatal 2-3 month; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
-1 | | Phf1 | 'recombinant human interleukin-2; 100 unit per milliliter; 16 hour' vs 'control; 0 hour' | compound, time | Transcription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2 |
-1 | | Phf1 | 'SARS coronavirus MA15' vs 'none' at '4 day' | infect, time | SM012 - SARS MA15 wild type, and SARS deltaORF6 mutant virus infections of C57BL6 mice - A time course |
-1 | | Phf1 | 'Influenza A virus (A/Puerto Rico/8/1934(H1N1)); 2 day' vs 'mock' in 'NOD/ShiLtJ' | infect, strain, time | Genomic profiling of collaborative cross founder mouse strains infected with respiratory viruses to discover novel transcripts and infection-related strain-specific gene and isoform expression |
-1 | | Phf1 | 'recombinant human interleukin-2; 100 unit per milliliter; 24 hour' vs 'control; 0 hour' | compound, time | Transcription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2 |
-1 | | Phf1 | 'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in' | genotype, growth condition | Transcription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock |
1 | | Phf1 | 'KDM4C knock-down' vs 'wild type genotype' in 'mixed-lineage leukemia' | clinical history, genotype | Targeting epigenetic networks mediated by Prmt1 and Kdm4c in acute myeloid leukemia |
