ENSMUSG00000025389 (Mip)

mus musculus

major intrinsic protein of lens fiber

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Mus musculus
Organism part
Showing 1 experiment:
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18 White et al
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Proteomics
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Transcriptomics
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Regulation
-1
-4.9
1
4.8
Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
8.3272 × 10-3-4.9
Mip'status epilepticus' vs 'none' in 'astrocyte; soticlestat; 30 milligram per kilogram'cell type, compound, diseaseRNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment
Adjusted p-valueLog2-fold change
7.7512 × 10-34.8
Mip'soticlestat; 30 milligram per kilogram' vs 'none' in 'astrocyte; none'cell type, compound, diseaseRNA-seq profiling of three distinct cell populations in a murine model of epilepsia with and without drug treatment
Adjusted p-valueLog2-fold change
8.7395 × 10-34
Mip'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
3.0137 × 10-22.3
Mip'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
9.4345 × 10-32.1
Mip'Triple knockout (Zfp36-/-, TNFR1-/-, TNFR2-/-)' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of douple (TNFR1-/-/TNFR2-/-) and triple (Zfp36-/-/TNFR1-/-/TNFR2-/-) knockout mouse spleens
Adjusted p-valueLog2-fold change
2.9094 × 10-21.8
Mip'actinomycin D; 4 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
3.7008 × 10-41.4
Mip'SMRT shRNA; CpG; 6 hour' vs 'none; none; 0 hour'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
5.4826 × 10-41.4
Mip'SMRT shRNA' vs 'none' in 'CpG' at '6 hour'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Adjusted p-valueLog2-fold change
2.658 × 10-21.4
Mip'FusΔNLS/+' vs 'wild type genotype' at '12 hour'genotype, timeMutant FUS triggers age-dependent synaptic impairment in presymptomatic ALS-FUS mice (RNA-seq part2)
Adjusted p-valueLog2-fold change
2.2553 × 10-3-1.1
Mip'Mettl6 knockout clone D1' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
3.4333 × 10-3-1.1
Mip'Mettl6 knockout clone G6' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
2.292 × 10-2-1.1
Mip'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
9.5454 × 10-3-1
Mip'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
1.7844 × 10-21
Mip'CpG; 6 hour' vs 'none; 0 hour' in 'SMRT shRNA'RNA interference, stimulus, timeRNA-seq of Control and SMRT KD CD8α+ DCs at 0hr and 6hr CpG stimulation
Synonym
Cts, shrivelled, MIP26, Svl, aquaporin 0, Lop, lens opacity, Aqp0
Ortholog
ENSPPYG00000004662 (Pongo abelii), mip (Xenopus tropicalis), mipa (Tetraodon nigroviridis), ENSDNOG00000030726 (Dasypus novemcinctus), ENSGGOG00000016571 (Gorilla gorilla), Eglp3 (Drosophila melanogaster), Eglp4 (Drosophila melanogaster), ENSAPLG00000024556 (Anas platyrhynchos), Eglp1 (Drosophila melanogaster), Eglp2 (Drosophila melanogaster), mipb (Tetraodon nigroviridis), ENSTNIG00000002388 (Salmo salar), ENSOARG00020002585 (Salmo salar), ENSSSCG00000000400 (Sus scrofa), ENSACAG00000016525 (Anolis carolinensis), MIP (Equus caballus), mipb (Danio rerio), FPS1 (Saccharomyces cerevisiae), ENSMODG00000021154 (Monodelphis domestica), MIP (Bos taurus), ENSOCUG00000022630 (Oryctolagus cuniculus), ENSCSAG00000005087 (Chlorocebus sabaeus), mipa (Danio rerio), AQY3 (Saccharomyces cerevisiae), ENSGALG00000042119 (Salmo salar), ENSACAG00000029542 (Anolis carolinensis), ENSPANG00000011371 (Papio anubis), Mip (Rattus norvegicus), MIP (Pan troglodytes)
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
4931463, 4442982, 17238318, 4444524, 5597746, 5504534, U27502_s_at, 10367173, 98796_at, 5336248, 1421039_at, 1435447_at, 5581973, ILMN_1254280, 4856295
Reactome pathway ID