ENSMUSG00000026497 (Mixl1)

mus musculus

Mix1 homeobox-like 1 (Xenopus laevis)

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Mus musculus
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Showing 1 experiment:
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Created with Highcharts 6.2.0brown adipose tissueinguinal fat padwhite adipose tissue
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Sun et al., 2020 - Organism part
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Proteomics
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Transcriptomics
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-2.9
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
9.3099 × 10-105.4
Mixl1'3 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
7.509 × 10-53.8
Mixl1'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
2.5454 × 10-23.1
Mixl1'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
3.7151 × 10-11-2.9
Mixl1'0.45 micromolar; 5-fluourouracil' vs 'none' at '24 hour'compound, timeTranscription profiling by array of mouse embryonic stem cells after treatment with 5-fluourouracil, methoxyacetic acid, monobutl phthalate, Penicillin G, retinoic acid or valproic acid
Adjusted p-valueLog2-fold change
2.3069 × 10-122.4
Mixl1'Drosha -/-' vs 'wild type genotype'genotypeRNA-seq of mouse ES cells with conditional Drosha knockout against wild type controls to identify pri-miRNAs
Adjusted p-valueLog2-fold change
9.3831 × 10-3-2.4
Mixl1'SGC-CBP30; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
7.0862 × 10-142.2
Mixl1'Setd5 homozygous (null) knockout' vs 'Setd5 heterozygous knockout'genotypeTranscriptional profiling of Setd5 heterozygous and knockout mouse embryonic stem cells
Adjusted p-valueLog2-fold change
7.2703 × 10-52.2
Mixl1'tumor' vs 'normal' in 'kidney'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
2.748 × 10-2-2.1
Mixl1'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.9248 × 10-21.9
Mixl1'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre-'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
3.4821 × 10-21.9
Mixl1'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte'cell type, compound, genotypeTranscription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin
Adjusted p-valueLog2-fold change
9.6405 × 10-41.8
Mixl1'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
3.0923 × 10-31.7
Mixl1'tumor' vs 'normal' in 'liver'clinical information, organism partPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
Adjusted p-valueLog2-fold change
3.2443 × 10-31.6
Mixl1'embryoid body' vs 'embryonic stem cell' on 'Affymetrix GeneChip Array 430A 2.0'developmental stageGene expression profile of J1 embryonic stem cells and J1 embryoid bodies
Adjusted p-valueLog2-fold change
9.7892 × 10-3-1.4
Mixl1'prostaglandin E2; 1 micromolar' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
4.5796 × 10-21.4
Mixl1'stabilization-competent' vs 'stabilization-incompetent' in '22 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
2.8729 × 10-7-1.1
Mixl1'12 nanomolar; retinoic acid' vs 'none' at '24 hour'compound, timeTranscription profiling by array of mouse embryonic stem cells after treatment with 5-fluourouracil, methoxyacetic acid, monobutl phthalate, Penicillin G, retinoic acid or valproic acid
Adjusted p-valueLog2-fold change
1.0534 × 10-51.1
Mixl1'96 hour' vs '0 hour' on 'Affymetrix Mouse430A_2 Array'timeTranscription profiling of murine V6.5 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation
Adjusted p-valueLog2-fold change
5.3866 × 10-41.1
Mixl1'BMP4 40 nanograms per milliliter' vs 'none'compound, doseTGF-beta and BMP mediated gene expression in cultured sclerotome.
Adjusted p-valueLog2-fold change
2.2087 × 10-51
Mixl1'4 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
1.5905 × 10-41
Mixl1'acetaldehyde; 30 micromolar' vs 'none' at '4-day differentiated'compound, sampling time pointTranscriptional profiling by array of mouse embryonic stem cells treated with six different compounds
Adjusted p-valueLog2-fold change
2.8944 × 10-3-1
Mixl1'chemical hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo.
Adjusted p-valueLog2-fold change
5.8917 × 10-3-1
Mixl1'vehicle control; Nrf2 knockout' vs 'vehicle control; wild type genotype'RNA interference, compound, genotypeCharacterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling
Adjusted p-valueLog2-fold change
2.5993 × 10-2-1
Mixl1'wild type genoytpe; siRNA Keap1-2' vs 'wild type genotype; scrambled shRNA'RNA interference, compound, genotypeCharacterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling
Adjusted p-valueLog2-fold change
3.4675 × 10-21
Mixl1'stabilization-competent' vs 'stabilization-incompetent' in '27 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture