6 | | Gnas | 'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-5.3 | | Gnas | 'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells' | age, cell type | Transcriptional profiling of nascent and mature pancreatic beta cells |
5.3 | | Gnas | 'actinomycin D; 4 hour' vs 'none' in 'Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-3.7 | | Gnas | 'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
3.5 | | Gnas | 'extracellular vesicle; non-stimulated culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
3.4 | | Gnas | 'Ngn3-expressing cell' vs 'Ngn3-null cell' | cell type | Transcriptional profiling of Ngn3-dependent pancreatic endocrine differentiation at E15.5 |
-3.3 | | Gnas | 'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-2.9 | | Gnas | 'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-2.9 | | Gnas | 'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
2.7 | | Gnas | 'actinomycin D; 8 hour' vs 'none' in 'Alb-Cre-ERT2 / Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
2.6 | | Gnas | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
2.6 | | Gnas | '7 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
2.5 | | Gnas | 'actinomycin D; 4 hour' vs 'none' in 'Alb-Cre-ERT2 / Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-2.5 | | Gnas | 'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
2.4 | | Gnas | '336 hour' vs '0 hour' on 'Affymetrix Mouse430A_2 Array' | time | Transcription profiling of murine V6.5 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation |
2.4 | | Gnas | '6 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
2.4 | | Gnas | '10 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
-2.3 | | Gnas | 'postnatal day 12' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
2.3 | | Gnas | '168 hour' vs '0 hour' on 'Affymetrix Mouse430A_2 Array' | time | Transcription profiling of murine V6.5 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation |
-2.3 | | Gnas | 'metaphase II oocyte' vs 'germinal vesicle oocyte' | cell type | Transcription profiling of mouse in vivo matured MII oocytes and fully in vivo grown germinal vesicle oocytes to identify gene transcripts linked to epigenetic reprogramming |
2.2 | | Gnas | 'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
2.2 | | Gnas | 'AZD5069; 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
2.2 | | Gnas | 'lipopolysaccharide; 10 nanogram per milliliter and PFI-1; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
2.1 | | Gnas | '5 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
2 | | Gnas | '4 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
2 | | Gnas | 'alpha-amanitin; maternal Ring1-Rnf+' vs 'none; maternal Ring1-Rnf+' | compound, genotype | Polycomb function during oogenesis is required for mouse early embryonic development (2-cell embryos) |
2 | | Gnas | 'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-2 | | Gnas | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
1.8 | | Gnas | 'Mettl6 knockout clone D1' vs 'wild type genotype' | genotype | METTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation |
-1.8 | | Gnas | 'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'brown adipose tissue' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
1.8 | | Gnas | 'PS2APP transgenic' vs 'non transgenic' in 'microglia cell' at '13 month' | age, cell type, genotype | Transcription profiling by high throughput sequencing of astrocytes, microglial and neuronal cells from an Alzheimer's mouse model |
-1.8 | | Gnas | 'cancer' vs 'normal' in 'lymph node medullary sinus macrophage' | cell type, disease | RNA Sequencing of CD169+ lymph node macrophages isolated from naïve or tumor-bearing mice |
1.7 | | Gnas | 'Mettl6 knockout clone G6' vs 'wild type genotype' | genotype | METTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation |
-1.7 | | Gnas | 'carcinoma' vs 'normal' | disease | Gene expression profile between normal mouse skin and carcinomas arising in the skin of RbF/F;K14creERTM;p107-/- mouse |
-1.7 | | Gnas | 'carboplatin; 30 milligram per kilogram' vs 'none' in '14 week; none' | age, irradiate | Pericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence |
1.6 | | Gnas | '14 day' vs '0 day' on 'Affymetrix Mouse430A_2 Array' | time | Transcription profiling of murine R1 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation |
1.6 | | Gnas | '96 hour' vs '0 hour' on 'Affymetrix Mouse430A_2 Array' | time | Transcription profiling of murine V6.5 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation |
1.6 | | Gnas | '3 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
1.6 | | Gnas | 'cut nerve; 7 day' vs 'none' | injury, protocol, time | Changes in the coding/non-coding transcriptome and DNA methylome that define the Schwann cell repair phenotype after nerve injury |
-1.5 | | Gnas | 'liver-specific Cnot3 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
-1.5 | | Gnas | 'Reverbαflox/floxAlbCreERT2+' vs 'wild type genotype' | genotype | Antibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq |
1.5 | | Gnas | 'co-transplanted with NOD-scid IL2Rgamma null HSCs' vs 'co-transplanted with wild type HSCs' | growth condition | RNA-seq of mouse wildtype HSCs purified from recipient mice co-transplanted with wildtype or different types of lymphoid cell deficient HSCs |
1.5 | | Gnas | '4 day' vs '0 day' on 'Affymetrix Mouse430A_2 Array' | time | Transcription profiling of murine R1 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation |
1.5 | | Gnas | 'R6/2 transgenic' vs 'wild type' in '12 week; striatum' | age, genotype, organism part | Transcription profiling by high throughput sequencing in wild type and R6/2 mutant mouse cortex and striatum at 8 and 12 weeks. |
1.5 | | Gnas | 'embryoid body' vs 'embryonic stem cell' on 'Affymetrix GeneChip Array 430A 2.0' | developmental stage | Gene expression profile of J1 embryonic stem cells and J1 embryoid bodies |
1.4 | | Gnas | 'induced neuronal cell' vs 'pluripotent embryonic stem cell' | phenotype | Transcription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells |
-1.4 | | Gnas | 'Reverbαflox/floxAlbCreERT2-' vs 'wild type genotype' | genotype | Antibody-independent ChIP-sequencing and liver-targeted deletion redefine REVERBα repressor function - RNA-seq |
1.4 | | Gnas | '7 day' vs '0 day' on 'Affymetrix Mouse430A_2 Array' | time | Transcription profiling of murine R1 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation |
1.4 | | Gnas | 'lipopolysaccharide; 10 nanogram per milliliter and SGC-CBP30; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
1.3 | | Gnas | '9 day' vs '0 day' on 'Affymetrix Mouse430A_2 Array' | time | Transcription profiling of murine R1 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation |
1.3 | | Gnas | 'Stella maternal / zygotic knockout' vs 'wild type genotype' in '2-cell embryo' | developmental stage, genotype | Transcription profiling of wild type and Stella knockout oocytes, wild type and Stella maternal/zygotic knockout embryos to study to the role of Stella in early mouse development |
1.2 | | Gnas | '2 day' vs '0 day' on 'Affymetrix Mouse430A_2 Array' | time | Transcription profiling of murine R1 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation |
1.2 | | Gnas | 'interferon gamma' vs 'none' | compound, stimulus | RNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone |
1.2 | | Gnas | 'doxycicline-mediated expression of c-Jun' vs 'control' | phenotype | Transcription profiling by array of mouse whole bone marrow after c-Jun induction |
1.2 | | Gnas | 'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'bER knockout' | compound, genotype | Laser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries |
-1.2 | | Gnas | '19BL; differentiated 3factor-reprogrammed induced pluripotent stem cell' vs 'R1; differentiated embryonic stem cell' at '11 day' | cell line, growth condition, time | Natural cardiogenesis-based template predicts cardiogenic potential of induced pluripotent stem cell lines |
-1.2 | | Gnas | 'Tet2 knockout' vs 'wild type' in 'hematopoietic stem cell' | cell type, genotype | Transcription profiling by high throughput sequencing of bone marrow stem and progenitor cells from Tet2 depleted mice |
-1.1 | | Gnas | '3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen' | genotype, organism part, sampling site | RNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls. |
1.1 | | Gnas | '1.5 day' vs '0 day' on 'Affymetrix Mouse430A_2 Array' | time | Transcription profiling of murine R1 embryonic stem cells differentiating into embryoid bodies over a time-course to study changes in transcription during stem cell differentiation |
1.1 | | Gnas | 'estradiol' at '30 hour' vs 'none' at '0 hour' | compound, time | Transcription profiling by array of G1E cells during time course treatment with estradiol. |
-1.1 | | Gnas | 'R1_Pax4+' at '0 day' vs 'wild type' at '0 day' | phenotype, time | Transcription profiling of mouse wild type R1 and cells expressing Pax4 following induction of pacreatic differentitation |
-1.1 | | Gnas | 'Pcl2 knockdown' vs 'control' | genotype | Gene expression profile in mouse embryonic stem cells in which endogenous Pcl2 expression was stably knocked down using short hairpin RNA |
1.1 | | Gnas | 'Lin- Dapi-EpCAM- CD31+td-tomato+' vs 'Lin- Dapi-EpCAM- CD31+td-tomato-' in 'vascular endothelial cell' | cell type, phenotype | Thymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche. |
-1.1 | | Gnas | 'SOD1-G93A transgenic' vs 'wild type' at 'day 65' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
-1.1 | | Gnas | 'osteosarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-1.1 | | Gnas | 'cardiotoxin; 10 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq comparison of fibro-adipogenic progenitors (FAPs) from wild type, mdx and cardiotoxin-injured mice |
1.1 | | Gnas | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
1 | | Gnas | 'beta(3)-adrenergic agonist Cl316,243' vs 'none' at '10 week' | age, stimulus | RNA-seq of age-associated transcriptome changes in brown adipose tissue |
-1 | | Gnas | 'liver-specific Cnot1 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
1 | | Gnas | '26 day' vs '0 day' | age | Gene expression profile of mouse differentiating embryonic stem cells (day 0, 6, 16, and 26) |
1 | | Gnas | 'dexamethasone; 100 nanomolar' vs 'none' | compound, stimulus | RNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone |
-1 | | Gnas | 'induced neural stem cell' vs 'mouse embryonic fibroblast cell' | cell type | Gene expression profile of mouse induced neural stem cells |
1 | | Gnas | '336 hour' vs '0 hour' on 'Affymetrix Mouse430A_2 Array' | time | Transcription profiling of murine J1 embryonic stem cells undergoing a differentiation time course to study changes in transcription during stem cell differentiation |
1 | | Gnas | 'oral hard palate epithelium' vs 'tail skin epithelium' | organism part | Transcriptional profiling of mouse oral and skin epithelium to study their intrinsic difference in global gene expression |
1 | | Gnas | '96 hour' vs '0 hour' on 'Affymetrix Mouse430A_2 Array' | time | Transcription profiling of murine J1 embryonic stem cells undergoing a differentiation time course to study changes in transcription during stem cell differentiation |
-1 | | Gnas | 'Mycobacterium tuberculosis H37Rv' vs 'none' | infect | The global transcriptome of whole lungs extracted from M. tuberculosis infected C57BL6 mice |
1 | | Gnas | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
1 | | Gnas | 'dexamethasone; 100 nanomolar; interferon gamma' vs 'none' | compound, stimulus | RNA-Seq of murine lung endothelial cells stimulated with IFN-gamma and dexamethasone |
1 | | Gnas | 'PS2APP transgenic' vs 'non transgenic' in 'microglia cell' at '7 month' | age, cell type, genotype | Transcription profiling by high throughput sequencing of astrocytes, microglial and neuronal cells from an Alzheimer's mouse model |
1 | | Gnas | 'calorie restricted diet' vs 'normal diet' at '15 month' | age, diet | Transcription profiling by array of cochleae from mice fed a calorie-restricted diet |
1 | | Gnas | 'Insm1-expressing/Pdx1-high expressing endocrine progenitor cell' vs 'Insm1-expressing/Pdx1-low expressing endocrine progenitor cell' in 'embryonic day 18.5' | cell type, developmental stage | Transcriptional regulation of endocrine cell differentiation by Insm1 |
-1 | | Gnas | 'PTEN null, P53-/-' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
1 | | Gnas | 'Id2_Id3_double knockout' vs 'wild type' in 'CD4+TCRb+CD8– cell; thymus' | cell type, genotype, organism part | Transcription profiling by high throughput sequencing of Id-proteins (Id2 and Id3) gene knockout cells |
