ENSMUSG00000028736 (Pax7)

mus musculus

paired box 7

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Mus musculus
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.5555 × 10-4-5.5
Pax7'70 week' vs '6 week' in 'none; none;age, irradiatePericyte induced reprogramming of the bone marrow microenvironment drives stem and cancer cell quiescence
Adjusted p-valueLog2-fold change
3.7132 × 10-11-5.2
Pax7'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
6.8499 × 10-7-4.2
Pax7'clear cell sarcoma; TATCre' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
3.7181 × 10-34.1
Pax7'AZD7507; AZD5069 (at same dosage); 100 milligram per kilogram' vs 'none'compoundRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Adjusted p-valueLog2-fold change
1.0428 × 10-24
Pax7'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control'cell type, growth conditionOSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells
Adjusted p-valueLog2-fold change
5.794 × 10-73.8
Pax7'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte'cell type, compound, genotypeTranscription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin
Adjusted p-valueLog2-fold change
1.7515 × 10-3-3.6
Pax7'clear cell sarcoma; Rosa26CreER' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
3.183 × 10-113.2
Pax7'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.273 × 10-42.6
Pax7'synovial sarcoma' vs 'normal'diseaseTranscription profiling by array of tumors excised from conditional mouse model of synovial sarcoma compared to skeletal muscle from wild type mice
Adjusted p-valueLog2-fold change
9.2725 × 10-32.5
Pax7'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell'age, cell type, phenotypeTranscription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture
Adjusted p-valueLog2-fold change
7.4796 × 10-32.4
Pax7'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype'compound, genotypeRNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence.
Adjusted p-valueLog2-fold change
6.92 × 10-62.2
Pax7'Triple knockout (Zfp36-/-, TNFR1-/-, TNFR2-/-)' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of douple (TNFR1-/-/TNFR2-/-) and triple (Zfp36-/-/TNFR1-/-/TNFR2-/-) knockout mouse spleens
Adjusted p-valueLog2-fold change
8.9505 × 10-5-2
Pax7'no limb muscle' vs 'wild type'phenotypeTranscription profiling by array of TS23 humerus tissue from muscle-less mutant (splotch-delayed) mice and control littermates to identify differentially expressed genes between muscle-less and control embryonic (TS23) humerus tissue, in order to determine mechanosensitive genes that impact skeletal development
Adjusted p-valueLog2-fold change
1.9885 × 10-3-1.9
Pax7'Sall4 homozygous knockout' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
4.1188 × 10-3-1.8
Pax7'129S1 allele at SNP rs50454566' vs 'wild type genotype'genotypeRNA-Seq of mouse embryonic stem cells derived from genetically diverse inbred mouse strains with varying alleles at Lifr gene
Adjusted p-valueLog2-fold change
4.9518 × 10-2-1.8
Pax7'XBP1s overexpression' vs 'wild type genotype' in '4μ8C; 15 micromolar'compound, genotypeOverexpression of spliced XBP1 in in vitro Th2 cells, and comparison to 4u8c treatment
Adjusted p-valueLog2-fold change
2.6602 × 10-3-1.6
Pax7'Mettl6 knockout clone D1' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
6.5593 × 10-6-1.4
Pax7'pre-B acute lymphoblastic leukemia 8093; nilotinib; 3 day' vs 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 0 day'cell type, compound, timeDrug tolerance development of mouse Bcr/Abl pre-B ALL cells on irradiated MEFs
Adjusted p-valueLog2-fold change
2.3962 × 10-41.4
Pax7'Smad4 mutant' vs 'control'genotypeGene expression profile of Myf5-Cre;Smad4flox/flox mutant
Adjusted p-valueLog2-fold change
8.394 × 10-51.3
Pax7'Men1-null' vs 'wild type'genotypeDifferentially regulated genes in adipocytes derived from Men1-null vs WT mouse embryonic stem cells
Adjusted p-valueLog2-fold change
2.3611 × 10-3-1.3
Pax7'mir181a1/b1 Knockout' vs 'wild type'genotypeMouse CD4+/CD8+ thymocytes from miR-181a1/b1 KO vs WT
Adjusted p-valueLog2-fold change
1.5814 × 10-51.2
Pax7'postnatal >1 year; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb'age, organism partExpression data from skeletal muscle satellite cells at different development stages
Adjusted p-valueLog2-fold change
1.7843 × 10-2-1.2
Pax7'3110043O21Rik knockout; spleen' vs 'wild type genotype; spleen'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
3.1875 × 10-51.1
Pax7'Double knockout (TNFR1-/-, TNFR2-/-)' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of douple (TNFR1-/-/TNFR2-/-) and triple (Zfp36-/-/TNFR1-/-/TNFR2-/-) knockout mouse spleens
Adjusted p-valueLog2-fold change
3.0087 × 10-41.1
Pax7'postnatal 2-3 month; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb'age, organism partExpression data from skeletal muscle satellite cells at different development stages
Adjusted p-valueLog2-fold change
9.6549 × 10-3-1.1
Pax7'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-'genotype, treatmentTIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury
Adjusted p-valueLog2-fold change
6.5474 × 10-4-1
Pax7'bisphenol AF; 10 micromolar' vs 'vehicle'compoundTranscriptomic analyses of 11.5 dpc female germ cell (mouse) exposed or not to Bisphenol A analogues (BPAF and BADGE)
Adjusted p-valueLog2-fold change
9.8483 × 10-4-1
Pax7'pre-B acute lymphoblastic leukemia 8093; lonafarnib; 4 day' vs 'pre-B acute lymphoblastic leukemia 8093; lonafarnib; 0 day'cell type, compound, timeDrug tolerance development of mouse Bcr/Abl pre-B ALL cells on irradiated MEFs
Adjusted p-valueLog2-fold change
2.289 × 10-3-1
Pax7'Wnt1Cre Ezh2lox/lox' vs 'control'genotypeExpression data from E11.5 mouse branchial arch 1 (BA1) - comparison between Ezh2lox/lox and Wnt1Cre Ezh2lox/lox embryos
Adjusted p-valueLog2-fold change
4.8207 × 10-31
Pax7'shRNA p68/p72 knockdown; differentiated' vs 'control; differentiated' on 'Affymetrix Array MOE430B'RNA interference, developmental stageTranscription profiling of p68/72 deficient C2C12 cells to investigate the function of p68/p72 in muscle gene expression and skeletal C2C12 cell differentiation.