-8.2 | | Mecr | 'Cox6a2 knockout' vs 'wild type' | phenotype | RNA-seq of PV+ interneurons in WT and Cox6a2-/- mice to unravel the molecular signaling that contributes to the increase in oxidative stress and metabolic dysregulation following Cox6a2 knockout. |
-4.7 | | Mecr | 'metaphase II oocyte' vs 'germinal vesicle oocyte' | cell type | Transcription profiling of mouse in vivo matured MII oocytes and fully in vivo grown germinal vesicle oocytes to identify gene transcripts linked to epigenetic reprogramming |
3 | | Mecr | 'brown adipose tissue' vs 'white adipose tissue' in 'chow; 23 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
-2.7 | | Mecr | 'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-2.6 | | Mecr | 'megakaryocyte' vs 'hematopoietic stem cell' | cell type | Transcription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells |
-2.4 | | Mecr | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
-2.3 | | Mecr | 'Irx3 knockout' vs 'control' at '7 day' | genetic modification, time | RNA-Seq of mouse Irx3-KO and Control ME3 cells on days 1 and 7 of adipogenic differentiation |
-2.3 | | Mecr | 'granulocyte' vs 'hemopoietic stem cell' | cell type | Gene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes. |
2.2 | | Mecr | 'Kit ligand' vs 'none' in 'wasp knockout' | compound, genotype | Transcription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand |
1.9 | | Mecr | 'Kit ligand' vs 'none' in 'wild type' | compound, genotype | Transcription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand |
-1.9 | | Mecr | 'myelocyte' vs 'hemopoietic stem cell' | cell type | Gene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes. |
-1.8 | | Mecr | '12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
-1.8 | | Mecr | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-1.7 | | Mecr | 'Bcl6 -/- BCR-ABL1-transformed B cell precursors; STI571 treated' vs 'Bcl6 -/- BCR-ABL1-transformed B cell precursors; untreated' | cell type, treatment | Gene expression data of BCR-ABL1 transformed B cell precursors from BCL6 wild-type and BCL6 knockout mice |
-1.7 | | Mecr | 'unilateral ureteral obstruction' vs 'sham' in 'TIMP3 -/-' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
1.6 | | Mecr | 'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
1.6 | | Mecr | 'doxycycline; 200 nanogram per milliliter; neoplasm; 5 day' vs 'none; normal; 0 day' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
-1.6 | | Mecr | 'colitis' at '8 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
-1.6 | | Mecr | 'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-' | cell type, phenotype | Thymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche. |
-1.6 | | Mecr | 'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'inguinal fat pad' | organism part, phenotype | RNA-seq to identify the role of mRNA decay in mouse adipose tissues |
-1.6 | | Mecr | 'transplanted secondary tumors' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
1.6 | | Mecr | 'dox-induced over-expression of oncogenes for 5 days' vs 'untreated control' | phenotype | Temporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice |
-1.6 | | Mecr | 'transgenic C3(1)-SV40Tag; 20 week' vs 'wild type; 8 week' | age, genotype | Prevention of mammary tumor progression by silencing HoxA1 via intraductal injection of nanoparticle-formulated siRNA |
1.6 | | Mecr | 'PTEN null' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
1.5 | | Mecr | 'RAW264.7 macrophage cell line; control' vs 'bone marrow macrophage; control' | cell type, growth condition | Transcription profiling of mouse bone marrow macrophages (BMM) compared to BMM co-cultured with 4T1.2 breast cancer cells, treated with tumour cell supernatant, or RAW macrophage cell line |
-1.4 | | Mecr | 'Bcl6 +/+ BCR-ABL1-transformed B cell precursors; STI571 treated' vs 'Bcl6 +/+ BCR-ABL1-transformed B cell precursors; untreated' | cell type, treatment | Gene expression data of BCR-ABL1 transformed B cell precursors from BCL6 wild-type and BCL6 knockout mice |
1.4 | | Mecr | 'PGC-1 beta knock in' vs 'wild type' | genotype | Transcription profiling by array of skeletal muscle from PGC-1 beta transgenic mice |
-1.4 | | Mecr | 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 3 day' vs 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 0 day' | cell type, compound, time | Drug tolerance development of mouse Bcr/Abl pre-B ALL cells on irradiated MEFs |
1.4 | | Mecr | 'trichostatin A and LIF' at '12 hour' vs 'none' at '0 hour' | compound, time | Transcription profiling of mouse embryonic stem cell line CGR8 grown in presence of Leukemia Inhibitory Factor and treated with trichostatin A |
1.4 | | Mecr | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
-1.3 | | Mecr | 'liver-specific Cnot3 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
-1.3 | | Mecr | 'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte' | cell type | Transcription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation |
1.3 | | Mecr | 'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-1.3 | | Mecr | 'mutant MyoD expression' at '24 hour' vs 'wild type MyoD expression' at '0 hour' | phenotype, time | Transcription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation. |
-1.3 | | Mecr | 'synovial sarcoma' vs 'control' | disease, genotype | Mouse Model of Clear Cell Sarcoma |
-1.3 | | Mecr | 'hepatocyte-specific Pten and Tgfbr2 knockout' vs 'wild type' | genotype | Hepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice |
1.3 | | Mecr | 'recombinant human interleukin-2; 100 unit per milliliter; 12 hour' vs 'control; 0 hour' | compound, time | Transcription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2 |
1.3 | | Mecr | 'recombinant human interleukin-2; 100 unit per milliliter; 10 hour' vs 'control; 0 hour' | compound, time | Transcription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2 |
1.3 | | Mecr | 'lung carcinoma' vs 'normal' in 'CD11b+Ly6G+ neutrophil' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
-1.3 | | Mecr | 'insulin-like growth factor-1' vs 'none' | compound | Gene expression profiling of murine T regulatory cells after insulin-like growth factor-1 stimulation |
1.2 | | Mecr | 'pabpn1l -/-' vs 'wild type genotype' in 'zygote' | genotype, organism part | RNA-seq of oocytes and zygotes from pabpn1l ko and wt female mice |
-1.2 | | Mecr | '3D culture' vs '2D culture' | growth condition | mRNA-seq of mouse salivary gland cancer cells cultured in adherent or non-adherent culture |
1.2 | | Mecr | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.2 | | Mecr | 'tumor' vs 'normal' in 'liver' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
-1.2 | | Mecr | 'hepatocyte-specific Pten knockout' vs 'wild type' | genotype | Hepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice |
1.2 | | Mecr | 'influenza' vs 'uninfected' in 'wild type' | compound, disease, genotype | Transcription profiling of mouse influenza virus infected in wild type and mutant animals revels induced gene expression changes of regional B cells are mediated in part through type I IFN |
1.2 | | Mecr | 'PTEN null, P53-/-' vs 'wild type genotype' | genotype | RNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice |
1.1 | | Mecr | 'brown adipose tissue' vs 'white adipose tissue' in 'high fat diet; 30 degree celsius' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
1.1 | | Mecr | 'α-GalCer; 2 microgram' vs 'none' in 'wild type genotype' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
1.1 | | Mecr | 'wild type; treated with angiotensin II and a combination of hydralazine and hydrochlorothiazide' vs 'wild type; vehicle' | genotype, treatment | Effect of Hypertension of Dendritic Cell Gene Expression |
-1.1 | | Mecr | '6 day' vs '0 day' | time | Transcription profiling by array of mouse colon tissues under dextran sodium sulphate induction for 2, 4 and 6 days against uninduced controls at day 0 |
-1.1 | | Mecr | 'undifferentiated' vs 'differentiated; rosiglitazone' in 'AKR/J' | phenotype, stimulus, strain | RNA-seq of mouse subcutaneous SVF cells before and after differentiation with a brown fat differentiation cocktail |
-1.1 | | Mecr | 'tumor' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
1.1 | | Mecr | 'DKO' vs 'wild type' | genotype | Transcription profiling by array of wild type and Hdac1 and 2 knockout lymphocytes |
1.1 | | Mecr | 'dominant-negative Brg1' vs 'wild type' | genotype | Transcription profiling by array of lens tissue from mice expressing a dnBrg1 transgenic construct |
-1.1 | | Mecr | 'unilateral ureteral obstruction' vs 'sham' in 'TIMP2 -/-' | genotype, treatment | TIMP2 and TIMP3 have divergent roles in early renal tubulointerstitial injury |
1.1 | | Mecr | 'chemical hypoxia' vs 'control' | growth condition | Comparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo. |
-1.1 | | Mecr | 'erythroblast' vs 'hematopoietic stem cell' | cell type | Transcription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells |
1.1 | | Mecr | 'recombinant human interleukin-2; 100 unit per milliliter; 16 hour' vs 'control; 0 hour' | compound, time | Transcription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2 |
-1.1 | | Mecr | 'Tbx5;Nkx2-5 knockout' vs 'wild type' | genotype | Transcription profiling by array of tbx5, nkx2-5 or both transcription factor knockouts during early heart formation in mouse |
1 | | Mecr | 'LDB1 knock-down with Ldb1 delta 4/5 construct' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
-1 | | Mecr | 'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'brown adipose tissue' | diet, organism part, temperature | RNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet |
1 | | Mecr | 'LDB1 knock-down' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
1 | | Mecr | 'M-CSF and FSL-1' at '3 day' vs 'none' at '0 day' | compound, time | Microarray profiling of polyploid macrophage progeny |
-1 | | Mecr | 'estradiol' at '30 hour' vs 'none' at '0 hour' | compound, time | Transcription profiling by array of G1E cells during time course treatment with estradiol. |
-1 | | Mecr | 'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal' | disease | Transcription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma |
-1 | | Mecr | 'liver-specific Cnot1 knockout' vs 'wild type' | phenotype | Roles of mRNA decay in liver development |
-1 | | Mecr | 'dibenzazapine 10 micromoles per kilogram' vs 'none' | compound, dose | Transcription profiling by array of pancreatic cells from C57BL/6 mice following dibenzazepine treatment |
-1 | | Mecr | 'tape stripping and oral administration of winged bean extract' vs 'tape stripping' | treatment | Transcription profiling by array of mouse dorsal skin after tape stripping and treatment with winged bean extract. |
1 | | Mecr | 'colitis' at '19 day' vs 'normal' at '0 day' | disease, time | Temporal transcriptomic changes during DSS colitis development and resolution. |
1 | | Mecr | 'Tfc knockout; thymic lymphoma' vs 'control' | disease, genotype | Gene expression in thymi of Tcf1 -/-, Tcf +/- or Tcf1 -/- mice with tumor. |
-1 | | Mecr | 'injected with sperm-derived RNA fragments from mice subjected to early life stress (MSUS)' vs 'injected with sperm-derived RNA fragments from control non-stressed mice' | stimulus | Zygotic expression after parental early life stress |
1 | | Mecr | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
1 | | Mecr | 'lipopolysaccharide' vs 'none' in 'bone marrow; wild type' | cell type, compound, genotype | Transcription profiling by high throughput sequencing of spleens of GPR34 knockout and wild type mice |
1 | | Mecr | 'recombinant human interleukin-2; 100 unit per milliliter; 8 hour' vs 'control; 0 hour' | compound, time | Transcription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2 |
-1 | | Mecr | 'azoxymethane and dextran sodium sulfate' vs 'control' in 'Myd88 knockout' | compound, genotype | Gene expression profiling of total colon in AOM/DSS-treated Myd88 knockout and wild type |
-1 | | Mecr | 'induction of polymicrobial sepsis' vs 'control' at '2 hour' in '1.5 to 3 month mice' | age, time, treatment | Aged Mice are Unable to Mount an Effective Myeloid Response to Sepsis |
1 | | Mecr | 'inducible deletion of Mll' vs 'control' | treatment | MLL regulated genes in LSK/CD48- hematopoietic stem cells |