4.1 | | Mlh1 | '4 hours after hCG treatment' vs 'control' in 'wild type' | genotype, treatment | The ISWI ATPase Snf2L is required for superovulation and regulates Fgl2 in differentiating mouse granulosa cells |
-4 | | Mlh1 | 'metaphase II oocyte' vs 'germinal vesicle oocyte' | cell type | Transcription profiling of mouse in vivo matured MII oocytes and fully in vivo grown germinal vesicle oocytes to identify gene transcripts linked to epigenetic reprogramming |
3.6 | | Mlh1 | 'pabpn1l -/-' vs 'wild type genotype' in 'zygote' | genotype, organism part | RNA-seq of oocytes and zygotes from pabpn1l ko and wt female mice |
-3.5 | | Mlh1 | 'Snfl2 Ex6DEL' vs 'wild type' in '4 hours after hCG treatment' | genotype, treatment | The ISWI ATPase Snf2L is required for superovulation and regulates Fgl2 in differentiating mouse granulosa cells |
-2.7 | | Mlh1 | 'granulocyte' vs 'hemopoietic stem cell' | cell type | Gene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes. |
2.3 | | Mlh1 | 'human chorionic gonadotropin; 5 International Unit' vs 'none' in 'bER knockout' | compound, genotype | Laser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries |
2 | | Mlh1 | 'TUT4; TUT7 double knockout' vs 'wild type' | phenotype | Microarray profiling of mouse pachytene cells deficient for UPF2 or both TUT4 and TUT7 |
1.8 | | Mlh1 | 'ABIN1[D485N] knock-in' vs 'wild type genotype' in 'classical monocyte' | cell type, genotype | RNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice |
-1.8 | | Mlh1 | 'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
1.7 | | Mlh1 | 'TUT4 deficiency; TUT7 knockout' vs 'wild type' | phenotype | Microarray profiling of mouse pachytene cells deficient for UPF2 or both TUT4 and TUT7 |
-1.6 | | Mlh1 | 'Helicobacter hepaticus' vs 'none' in 'Alpk1 homozygous knockout' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
-1.6 | | Mlh1 | 'Helicobacter hepaticus' vs 'none' in 'wild type phenotype' | infect, phenotype | Whole transcriptome profiling of the steady state and Hh-treated (8 hrs) Alpk1+/- (heterozygous) and Alpk1-/- (knockout) BMDMs using RNA-Sequencing approach |
-1.6 | | Mlh1 | 'Myd88 -/- mutant' vs 'wild type' in 'liver; GF' | genotype, growth condition, organism part | Transcriptional profiling of 53 tissue samples from germ-free and conventionally raised mice |
1.6 | | Mlh1 | 'bER knockout' vs 'wild type' in 'human chorionic gonadotropin; 5 International Unit' | compound, genotype | Laser Capture Microdissection isolation of preovulatory granulosa cells from WT and bERKO ovaries |
1.5 | | Mlh1 | 'lung carcinoma' vs 'normal' in 'CD11b+Ly6G+ neutrophil' | cell type, disease | Transcriptome analysis of isolated stormal cells and tumor epithelial cells in mouse lung cancer by RNA-Seq |
-1.5 | | Mlh1 | 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 3 day' vs 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 0 day' | cell type, compound, time | Drug tolerance development of mouse Bcr/Abl pre-B ALL cells on irradiated MEFs |
-1.4 | | Mlh1 | 'lipopolysaccharide; 10 nanogram per milliliter and PFI-1; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.4 | | Mlh1 | 'lipopolysaccharide; 10 nanogram per milliliter and prostaglandin E2; 1 micromolar and interferon beta; 100 units per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
1.4 | | Mlh1 | 'acute graft vs. host disease; T-cell depleted bone marrow + T cells transplant' vs 'normal; T-cell depleted bone marrow transplant' | disease, stimulus | RNA-Seq of lymph node fibroblastic reticular cells isolated from bone marrow transplant recipient mice with or without acute Graft-versus-host disease on day 7 or untransplanted control mice |
1.4 | | Mlh1 | 'RAW264.7 macrophage cell line; control' vs 'bone marrow macrophage; control' | cell type, growth condition | Transcription profiling of mouse bone marrow macrophages (BMM) compared to BMM co-cultured with 4T1.2 breast cancer cells, treated with tumour cell supernatant, or RAW macrophage cell line |
-1.4 | | Mlh1 | 'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
-1.3 | | Mlh1 | '3D culture' vs '2D culture' | growth condition | mRNA-seq of mouse salivary gland cancer cells cultured in adherent or non-adherent culture |
-1.3 | | Mlh1 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.3 | | Mlh1 | 'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.3 | | Mlh1 | 'lipopolysaccharide; 1 microgram per milliliter' vs 'none' in 'Nfkbiz-/-' | compound, genotype | Inhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2) |
-1.3 | | Mlh1 | 'hepatocyte-specific deletion of JAK2' vs 'wild type genotype' in '40 week' | age, genotype | Hepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice |
1.3 | | Mlh1 | 'conditional UPF2 knockout; 36 hour after partial hepatechtomy' vs 'control; 36 hour after partial hepatechtomy' | genotype, sampling time | Transcription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy |
-1.3 | | Mlh1 | 'hepatocyte-specific Pten and Tgfbr2 knockout' vs 'wild type' | genotype | Hepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice |
1.3 | | Mlh1 | 'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast' | cell type, phenotype | Transcription profiling by array of differentiating primary primitive and definitive mouse red blood cells |
1.3 | | Mlh1 | 'Yersinia pestis' vs 'control' in 'neutrophil' | cell type, infect, sampling site | Spatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague |
-1.2 | | Mlh1 | 'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none' | compound, genotype, time | RNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice |
-1.2 | | Mlh1 | '10 day' vs '0 day' | age | Transcription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies |
1.2 | | Mlh1 | 'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl' | cell type, genotype | RNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system |
-1.2 | | Mlh1 | 'Myd88 -/-' vs 'wild type genotype' in 'raised in germ-free environment; jejunum' | environmental history, genotype, organism part | Transcriptional profiling of intestinal tissue samples from germ-free and conventionally raised mice which are either wild-type or Myd88-/- |
1.2 | | Mlh1 | 'V6.5; embryonic stem cell’ vs 'wild type; endothelial' | cell line, cell type, genotype | CD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors |
1.2 | | Mlh1 | 'conditional UPF2 knockout; before partial hepatechtomy' vs 'control; before partial hepatechtomy' | genotype, sampling time | Transcription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy |
1.2 | | Mlh1 | 'upf3 knockout' vs 'wild type' in 'testis' | cell type, genotype | UPF2 establishes testis-specific transcriptome enriched in transcripts with shorter 3’UTRs |
1.2 | | Mlh1 | 'recombinant human interleukin-2; 100 unit per milliliter; 16 hour' vs 'control; 0 hour' | compound, time | Transcription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2 |
-1.2 | | Mlh1 | 'postnatal 2-3 month; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
-1.2 | | Mlh1 | 'Gata6 knockout' vs 'wild type' | phenotype | Global gene expression in the adult Gata6 null mouse pancreas |
1.1 | | Mlh1 | 'LDB1 knock-down with Ldb1 delta 4/5 construct' vs 'control shRNA' | RNA interference | Role of LDB1 in the transition from chromatin looping to transcription activation |
-1.1 | | Mlh1 | 'doxorubicin; 17.5 milligram per kilogram body weight' vs 'vehicle' in 'scramble; podocyte' | cell type, compound, genotype | Transcription profiling to identify the role of MOF in primary MEFs and differentiated podocytes in response to Adriamycin |
-1.1 | | Mlh1 | 'lipopolysaccharide; 10 nanogram per milliliter and SGC-CBP30; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype' | cell line, compound, genotype | Bulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions |
-1.1 | | Mlh1 | 'Soulatrolide; 20 milligram per kilogram per day' vs 'control; ' | compound | Toxicogenomics on mice liver of coumarins from Calophyllum brasiliense |
1.1 | | Mlh1 | 'dox-induced over-expression of oncogenes for 5 days' vs 'untreated control' | phenotype | Temporal Transcriptional Profiling in response to cMYC and KrasG12D Expression and Inactivation in In Vitro Cultured Primary Mammary Epithelial Cells of Adult Virgin Mice |
-1.1 | | Mlh1 | 'Myd88 -/-' vs 'wild type genotype' in 'raised in germ-free environment; proximal colon' | environmental history, genotype, organism part | Transcriptional profiling of intestinal tissue samples from germ-free and conventionally raised mice which are either wild-type or Myd88-/- |
1.1 | | Mlh1 | 'stabilization-competent' vs 'stabilization-incompetent' in '23 day; secondary reprogramming cell' | age, cell type, phenotype | Transcription profiling by high throughput sequencing in gene expresion profile of 4 SC clones and 4 SI clones at different time points defined a stabilization competency signiture |
-1.1 | | Mlh1 | 'Myd88 -/-' vs 'wild type genotype' in 'raised in germ-free environment; ileum' | environmental history, genotype, organism part | Transcriptional profiling of intestinal tissue samples from germ-free and conventionally raised mice which are either wild-type or Myd88-/- |
-1.1 | | Mlh1 | 'Myd88 -/- mutant' vs 'wild type' in 'subcutaneous fat; GF' | genotype, growth condition, organism part | Transcriptional profiling of 53 tissue samples from germ-free and conventionally raised mice |
1.1 | | Mlh1 | 'recombinant human interleukin-2; 100 unit per milliliter; 12 hour' vs 'control; 0 hour' | compound, time | Transcription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2 |
1.1 | | Mlh1 | 'ko cyld-/-' vs 'wild type' | genotype | Transcription profiling by array of mouse liver with Cyld inactivation |
-1.1 | | Mlh1 | 'Myd88 -/- mutant' vs 'wild type' in 'epidimymal fat; GF' | genotype, growth condition, organism part | Transcriptional profiling of 53 tissue samples from germ-free and conventionally raised mice |
-1.1 | | Mlh1 | 'hepatocyte-specific Pten knockout' vs 'wild type' | genotype | Hepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice |
-1.1 | | Mlh1 | 'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
-1.1 | | Mlh1 | 'liver-specific Pit1 knockout' vs 'wild type genotype' in 'regular chow diet' | diet, genotype | Transcription profiling by array of liver tissues from mice with liver-specific knockout of Pit1 and wild-type littermates fed with either a high-fat diet or chow control diet |
1 | | Mlh1 | 'α-GalCer; 2 microgram' vs 'none' in 'Cd1d homozyous knockout' | compound, genotype | CD1d-dependent immune suppression mediated by regulatory B cells through modulations of iNKT cells |
-1 | | Mlh1 | '12 day' vs '5 day' in 'doxycycline; 200 nanogram per milliliter; neoplasm' | compound, phenotype, time | RNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls |
1 | | Mlh1 | 'epithelium-specific mutant beta-catenin expression' vs 'wild type' | phenotype | RNAseq of murine small intestinal tissue following epithelium-specific deletion of Bcl9/9l +/- Apc +/- mutant B-catenin |
-1 | | Mlh1 | 'Double knockout (TNFR1-/-, TNFR2-/-)' vs 'wild type' | genotype | Transcription profiling by high throughput sequencing of douple (TNFR1-/-/TNFR2-/-) and triple (Zfp36-/-/TNFR1-/-/TNFR2-/-) knockout mouse spleens |
-1 | | Mlh1 | 'none; wasp knockout' vs 'none; wild type' | compound, genotype | Transcription profiling of bone marrow–derived mast cells from WASP-deficient mice after stimulation with kit ligand |
-1 | | Mlh1 | 'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line' | clinical information, infect | Gene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium |
-1 | | Mlh1 | 'fasted' vs 're-fed' in 'wild type genotype; Gabpa miRNA' | RNA interference, diet, genotype | Gene expression profiling of liver from C57BLKS/J and db/db 8 mice with an AAV harboring a control or GAbpa-specific miRNA under the LP1 promoter |
-1 | | Mlh1 | 'postnatal >1 year; hindlimb' vs 'embryonic day 17.5; whole forelimb and hindlimb' | age, organism part | Expression data from skeletal muscle satellite cells at different development stages |
-1 | | Mlh1 | 'myelocyte' vs 'hemopoietic stem cell' | cell type | Gene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes. |
1 | | Mlh1 | 'UPF2 knockout' vs 'wild type' | phenotype | Microarray profiling of mouse pachytene cells deficient for UPF2 or both TUT4 and TUT7 |
1 | | Mlh1 | 'recombinant human interleukin-2; 100 unit per milliliter; 10 hour' vs 'control; 0 hour' | compound, time | Transcription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2 |
-1 | | Mlh1 | 'Alb-Cre;VHLf/f' vs 'Alb-Cre' | genotype | Transcription profiling by array of mice with liver-specific expression of hypoxia inducible factor, or inactivated von Hippel-Lindau tumor suppressor |
-1 | | Mlh1 | 'induction of polymicrobial sepsis' vs 'control' at '24 hour' in '1.5 to 3 month mice' | age, time, treatment | Aged Mice are Unable to Mount an Effective Myeloid Response to Sepsis |
1 | | Mlh1 | 'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector' | genotype | RNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice |
-1 | | Mlh1 | 'induction of polymicrobial sepsis' vs 'control' at '72 hour' in '1.5 to 3 month mice' | age, time, treatment | Aged Mice are Unable to Mount an Effective Myeloid Response to Sepsis |
