ENSMUSG00000038069 (Cdkn2aip)

mus musculus

CDKN2A interacting protein

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Mus musculus
Organism part
Showing 42 experiments:
Created with Highcharts 6.2.0adrenal glandcentral neural epitheliumdorsal control neural epitheliumheart left ventricleleft cardiac atriummuscle tissueright cardiac atriumthymusblood plasmabronchuscorpora quadrigeminadentate gyrus of hippocampal formationepidermal ectodermeyeball of camera-type eyehypothalamusintestinemandibular archmedulla oblongataolfactory epitheliumpituitary glandskeletal muscle tissuestriatumuteruswhite adipose tissue
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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9
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9 in 3 strains - C57BL/6
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14 - embryonic day 10.5
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Mammalian Kaessmann
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6
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Vertebrates
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4
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Fat and muscle
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Developing gut
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3 Soumillon et al
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3
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Sun et al., 2020 - Organism part
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - C57BL/6J
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - adult
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2
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49 FANTOM5 project - juvenile
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4 Bonthuis et al - Idaho derived wild …
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Organism part - Geiger et al
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Organism part - Huttlin et al
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Huttlin et al., 2010 - tissues - brain, …
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Organism part - Malmstrom et al - , …
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Linscheid et al., 2021 - tissue - heart …
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Duda et al., 2018 - organism part - …
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Duda et al., 2018 - organism part - …
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Linscheid et al. 2019 - organism part
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Zhao et al., 2019 - tissue - lens
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Organism part - Malmstrom et al - , …
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Organism part - Malmstrom et al - , …
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Deshmukh et al., 2015 - organism part
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Proteomics
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Transcriptomics
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
8.0186 × 10-43
Cdkn2aip'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
7.903 × 10-52.9
Cdkn2aip'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'wild type'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
1.3308 × 10-32.9
Cdkn2aip'conditional UPF2 knockout; 36 hour after partial hepatechtomy' vs 'control; 36 hour after partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
2.819 × 10-52.5
Cdkn2aip'conditional UPF2 knockout; before partial hepatechtomy' vs 'control; before partial hepatechtomy'genotype, sampling timeTranscription profiling of livers of adult UPF2 null mice in response to partial hepatechtomy
Adjusted p-valueLog2-fold change
1.2228 × 10-7-2.2
Cdkn2aip'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
3.4596 × 10-51.9
Cdkn2aip'Rb;E2f8 knock-out' vs 'wild type'genotypeExpression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells
Adjusted p-valueLog2-fold change
1.3891 × 10-21.8
Cdkn2aip'Lin- Dapi-EpCAM- CD31+td-tomato+' vs 'Lin- Dapi-EpCAM- CD31+td-tomato-' in 'vascular endothelial cell'cell type, phenotypeThymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche.
Adjusted p-valueLog2-fold change
2.9773 × 10-21.7
Cdkn2aip'Upf2fl/fl;LysMCre' vs 'wild type genotype' in 'macrophage'cell type, genotypeTranscription profiling of mouse T-cell thymocytes and bone marrow-derived macrophages dervied from Upf2fl/fl;LysMCre and Upf2fl/fl;LckCre mice to test the importance of nonsense-mediated mRNA decay on global transcription
Adjusted p-valueLog2-fold change
1.2462 × 10-7-1.6
Cdkn2aip'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
2.3053 × 10-71.6
Cdkn2aip'myeloid lineage restricted progenitor cell' vs 'long term hematopoietic stem cell' in 'Elp3fl/fl'cell type, genotypeRNA-seq of long-term hematopoietic stem cells and myeloid progenitors of control mice or mice conditionally deficient for Trp53 or Elp3 or both genes in the hematopoietic system
Adjusted p-valueLog2-fold change
5.3959 × 10-51.6
Cdkn2aip'E2f8 knock-out' vs 'wild type'genotypeExpression data from WT, E2f8 KO, Rb KO and Rb;E2f8 DKO spleen Ter19+CD71high sorted cells
Adjusted p-valueLog2-fold change
1.1572 × 10-51.5
Cdkn2aip'confluent monolayer on collagen' at '7 day' vs 'freshly isolated' at '0 day'growth condition, timeTranscription profiling of primary mouse hepatocytes under different culture conditions
Adjusted p-valueLog2-fold change
2.2832 × 10-4-1.5
Cdkn2aip'Yersinia pestis' vs 'control' in 'neutrophil'cell type, infect, sampling siteSpatially distinct neutrophil responses within the inflammatory lesions of pneumonic plague
Adjusted p-valueLog2-fold change
2.2361 × 10-30-1.4
Cdkn2aip'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'primary cell line; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
6.1483 × 10-26-1.4
Cdkn2aip'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
1.4527 × 10-71.4
Cdkn2aip'MG132; 1 micromolar' vs 'DMSO' in 'CHOP-/-'compound, genotypeMicroarray to find CHOP dependent genes in response to proteasome inhibition
Adjusted p-valueLog2-fold change
8.0871 × 10-3-1.4
Cdkn2aip'CD34+ keratinocyte' vs 'CD34-keratinocyte'cell typeAkt signalling leads to stem cell activation and promotes tumour development in epidermis.
Adjusted p-valueLog2-fold change
6.1593 × 10-3-1.3
Cdkn2aip'Mxd1 knockdown by siRNA' vs 'wild type' at '1 day'phenotype, time3' RNA-seq of differentiating (brown) mouse subcutaneous SVF cells upon knockdown of Zfp521, Fhl1, or Mxd1
Adjusted p-valueLog2-fold change
1.3743 × 10-41.2
Cdkn2aip'trichostatin A and LIF' at '6 hour' vs 'none' at '0 hour'compound, timeTranscription profiling of mouse embryonic stem cell line CGR8 grown in presence of Leukemia Inhibitory Factor and treated with trichostatin A
Adjusted p-valueLog2-fold change
2.2042 × 10-3-1.2
Cdkn2aip'PTEN null, P53-/-' vs 'wild type genotype'genotypeRNA seq of prostate gland from WT, PTEN pc -/- and PTEN pc-/-;P53 -/- mice
Adjusted p-valueLog2-fold change
1.4374 × 10-21.2
Cdkn2aip'interferon beta' vs 'none' in 'wild type; uninfected'compound, disease, genotypeTranscription profiling of mouse influenza virus infected in wild type and mutant animals revels induced gene expression changes of regional B cells are mediated in part through type I IFN
Adjusted p-valueLog2-fold change
8.4961 × 10-33-1.1
Cdkn2aip'Salmonella enterica serovar Typhimurium' vs 'control' in 'derived macrophage from E14 Traf2 mutant cell line'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
3.4978 × 10-29-1.1
Cdkn2aip'Salmonella enterica serovar Typhimurium' vs 'control' in 'bone marrow macrophage from 129P2 mouse strain'clinical information, infectGene expression profiles of mouse embryonic stem cell derived macrophages infected with Salmonella typhimurium
Adjusted p-valueLog2-fold change
3.9382 × 10-71.1
Cdkn2aip'MG132; 1 micromolar' vs 'DMSO' in 'wild type'compound, genotypeMicroarray to find CHOP dependent genes in response to proteasome inhibition
Adjusted p-valueLog2-fold change
1.5945 × 10-61.1
Cdkn2aip'West Nile virus; late stage encephalitis' vs 'early stage encephalitis'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
6.6932 × 10-61.1
Cdkn2aip'chronic pancreatitis' vs 'control'diseasePancreatic gene expression associated with cerulein induced chronic pancreatitis in mice
Adjusted p-valueLog2-fold change
4.4028 × 10-51.1
Cdkn2aip'3 day' vs '0 day'ageTranscription profiling of mouse embyronic stem cell line CGR8 during the first 10 days of differentiation into embryoid bodies
Adjusted p-valueLog2-fold change
1.2602 × 10-41.1
Cdkn2aip'trichostatin A and LIF' at '12 hour' vs 'none' at '0 hour'compound, timeTranscription profiling of mouse embryonic stem cell line CGR8 grown in presence of Leukemia Inhibitory Factor and treated with trichostatin A
Adjusted p-valueLog2-fold change
6.3209 × 10-41.1
Cdkn2aip'induce erythroid differentiation' vs 'none' in 'wild type'genotype, stimulusTranscription profiling by array of Mouse erythro-leukaemia cells during differentiation to investigate the influence of Runx1 transcription factor
Adjusted p-valueLog2-fold change
3.6756 × 10-211
Cdkn2aip'nmf205, Gcn2 double mutant' vs 'wild type'genotypeTranscription profiling by high throughput sequencing in cerebellum of mouse Gcn2 -/-, nmf205-/- and nmf205-/-;Gcn2-/-
Adjusted p-valueLog2-fold change
3.2591 × 10-81
Cdkn2aip'West Nile virus; late stage encephalitis' vs 'mock infection'infect, timeTranscriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection
Adjusted p-valueLog2-fold change
1.9734 × 10-4-1
Cdkn2aip'recombinant human interleukin-2; 100 unit per milliliter; 8 hour' vs 'control; 0 hour'compound, timeTranscription profiling by array of mouse CTLL-2 cell line treated with recombinant human interleukin-2
Adjusted p-valueLog2-fold change
3.9368 × 10-4-1
Cdkn2aip'Plasmodium chabaudi infection' vs 'no infection' in 'adjuvant only'infect, treatmentProtective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase
Adjusted p-valueLog2-fold change
4.5137 × 10-4-1
Cdkn2aip'pre-B acute lymphoblastic leukemia 8093; nilotinib; 3 day' vs 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 0 day'cell type, compound, timeDrug tolerance development of mouse Bcr/Abl pre-B ALL cells on irradiated MEFs
Adjusted p-valueLog2-fold change
3.7302 × 10-31
Cdkn2aip'V6.5; embryonic stem cell’ vs 'wild type; endothelial'cell line, cell type, genotypeCD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors
Adjusted p-valueLog2-fold change
6.4248 × 10-31
Cdkn2aip'erythroblast' vs 'hematopoietic stem cell'cell typeTranscription profiling by array of primary megakaryocytes (MEG) and erythroblasts (ERY) developed from murine fetal liver hematopoietic stem cells
Adjusted p-valueLog2-fold change
8.7636 × 10-3-1
Cdkn2aip'Ckit negative' vs 'Ckit positive'cell typeGene expression profile of c-kit positive and c-kit negative cells
Adjusted p-valueLog2-fold change
1.6588 × 10-21
Cdkn2aip'RA839; Nrf2 knockout' vs 'RA839; wild type genotype'RNA interference, compound, genotypeCharacterization of RA839, a non-covalent small-molecule binder to Keap1 and selective activator of Nrf2 signalling
Adjusted p-valueLog2-fold change
4.9076 × 10-2-1
Cdkn2aip'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells