ENSMUSG00000038160 (Atg5)

mus musculus

autophagy related 5

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Mus musculus
Organism part
Showing 48 experiments:
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Created with Highcharts 6.2.0adrenal glandaxillary lymph nodebronchuscentral neural epitheliumcorpora quadrigeminadifferentiated myotubeepididymisforelimbhippocampal formationintestinal mucosalateral prominence neural epitheliummandibular archmedulla oblongatanon-floor plate neural epitheliumolfactory pitpituitary glandskeletal muscle tissuestomachtestisurinary bladdervomeronasal organzone of skin
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49 FANTOM5 project - adult
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49 FANTOM5 project - neonate
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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49 FANTOM5 project - embryonic day 15
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49 FANTOM5 project - embryonic day 14
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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9
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49 FANTOM5 project - embryonic day 12
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9 in 3 strains - C57BL/6
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14 - embryonic day 10.5
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49 FANTOM5 project - embryonic day 13
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Mammalian Kaessmann
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6
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Vertebrates
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Fat and muscle
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Developing gut
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49 FANTOM5 project - embryonic day 11
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3 Soumillon et al
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3
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Sun et al., 2020 - Organism part
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - C57BL/6J
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Mernberger et al 2019 - Organism Part
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - lactating adult …
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49 FANTOM5 project - embryonic day 17.5
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49 FANTOM5 project - embryonic day 14.5
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49 FANTOM5 project - embryo
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4 Bonthuis et al - Idaho derived wild …
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Deshmukh et al., 2015 - organism part
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Proteomics
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Transcriptomics
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-1
-1.8
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1.4
Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
3.2309 × 10-3-1.8
Atg5'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
6.9076 × 10-5-1.6
Atg5'Plasmodium chabaudi infection' vs 'no infection' in 'adjuvant only'infect, treatmentProtective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase
Adjusted p-valueLog2-fold change
2.58 × 10-4-1.6
Atg5'Albumin Cre+/-;Hnf4a fl/fl' vs 'wild type genotype'genotypeTranscription profiling by array of liver-specific Hnf4alpha knock-out mice
Adjusted p-valueLog2-fold change
5.6689 × 10-3-1.6
Atg5'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'reticulocyte'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
6.9757 × 10-5-1.5
Atg5'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'mix of orthochromatic and polychromatophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
4.6535 × 10-6-1.4
Atg5'transgenic' vs 'wild type' in '121 day; 129Sv'age, genotype, strainWhole genome transcriptome analysis identifies indices of fast and slow disease progression in two ALS mouse models
Adjusted p-valueLog2-fold change
1.3591 × 10-31.4
Atg5'alpha-amanitin; maternal Ring1-Rnf+' vs 'none; maternal Ring1-Rnf+'compound, genotypePolycomb function during oogenesis is required for mouse early embryonic development (2-cell embryos)
Adjusted p-valueLog2-fold change
5.6425 × 10-8-1.3
Atg5'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
8.1765 × 10-51.3
Atg5'TUT4 deficiency; TUT7 knockout' vs 'wild type'phenotypeMicroarray profiling of mouse pachytene cells deficient for UPF2 or both TUT4 and TUT7
Adjusted p-valueLog2-fold change
1.8238 × 10-4-1.3
Atg5'lipopolysaccharide; 1 microgram per milliliter' vs 'none' in 'Nfkbiz-/-'compound, genotypeInhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2)
Adjusted p-valueLog2-fold change
2.0766 × 10-6-1.2
Atg5'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; wild type genotype'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
3.7083 × 10-41.2
Atg5'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'wild type'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
5.441 × 10-41.2
Atg5'granulocyte' vs 'hemopoietic stem cell'cell typeGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Adjusted p-valueLog2-fold change
1.3213 × 10-13-1.1
Atg5'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
4.4261 × 10-10-1.1
Atg5'5 week' vs '1 week' in 'Jak2+/V617F; CRISPR/Cas9 mediated knockout of Dnmt3a'genotype, timeRNA-seq of Jak2VF LSK cells transduced with Dnmt3a-Cas9-GFP lentivirus vs. emp-Cas9-GFP controls one week and five weeks post methylcellulose plating
Adjusted p-valueLog2-fold change
4.3828 × 10-4-1.1
Atg5'side population cells' vs 'main population cells' in 'bone marrow'cell type, organism partGene expression of side population and main population cells, isolated from adult murine skeletal muscle and bone marrow
Adjusted p-valueLog2-fold change
1.0841 × 10-31.1
Atg5'TUT4; TUT7 double knockout' vs 'wild type'phenotypeMicroarray profiling of mouse pachytene cells deficient for UPF2 or both TUT4 and TUT7
Adjusted p-valueLog2-fold change
1.1251 × 10-3-1.1
Atg5'lipopolysaccharide; 1 microgram per milliliter' vs 'none' in 'wild type'compound, genotypeInhibitor of NFκB ζ (IκBζ) is a transcriptional key regulator of monocyte chemoattractant protein-1 (MCP-1/CCL2)
Adjusted p-valueLog2-fold change
1.2139 × 10-31.1
Atg5'chronic cystitis' vs 'none' in 'C57/Bl6'disease, strainChronic cystitis microarray comparing C3H/HeN and C57BL/6 bladder gene expression
Adjusted p-valueLog2-fold change
1.856 × 10-3-1.1
Atg5'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
4.5867 × 10-31.1
Atg5'chemical hypoxia' vs 'control'growth conditionComparison of gene expression in whole blood of mice subjected to chemical hypoxia in vivo.
Adjusted p-valueLog2-fold change
1.6473 × 10-9-1
Atg5'tape stripping and oral administration of winged bean extract' vs 'tape stripping'treatmentTranscription profiling by array of mouse dorsal skin after tape stripping and treatment with winged bean extract.
Adjusted p-valueLog2-fold change
7.1535 × 10-7-1
Atg5'lipopolysaccharide; 10 nanogram per milliliter' vs 'none' in 'Hoxb8-FL; MEF2A knockout'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.4736 × 10-61
Atg5"98 to 119 week; reproductively old" vs "6 to 12 week; reproductively young"age, phenotypeRNAseq of whole ovarian follicles from young and old mice.
Adjusted p-valueLog2-fold change
1.4239 × 10-5-1
Atg5'antibiotics, CCl4 and diethylnitrosamine' vs 'none' in 'wild type genotype'genotype, treatmentGene expression accompanying the promotion of hepatocellular carcinoma by intestinal microbiota and Tlr4 in mice.
Adjusted p-valueLog2-fold change
5.8043 × 10-51
Atg5'Mycobacterium tuberculosis; D2.B6-Chr19 congenic; 70 day' vs 'control; D2.B6-Chr19 congenic; 0 day'infect, strain, timeTranscription profiling of mouse lung from C57BL6 and DBA2 parental strains and D2.B6-Chr7 and D2.B6-Chr19 congenic mice following aerosol infection with Mycobacterium tuberculosis for 30 and 70 days
Adjusted p-valueLog2-fold change
7.4605 × 10-51
Atg5'MEF2A knockout' vs 'wild type genotype' in 'Hoxb8-FL; lipopolysaccharide; 10 nanogram per milliliter'cell line, compound, genotypeBulk RNA-seq of wild type and MEF2A or MEF2C/D knockout mouse bone marrow macrophages under different stimulation conditions
Adjusted p-valueLog2-fold change
1.018 × 10-41
Atg5'mutant MyoD expression' at '24 hour' vs 'control' at '24 hour'phenotype, timeTranscription profiling of mouse embryoic fibroblasts expressing wild type MyoD or its non-acetylatable version MyoD RRR to investigate how MyoD acetylation may contribute to differential gene activation.
Adjusted p-valueLog2-fold change
1.2499 × 10-4-1
Atg5'pre-B acute lymphoblastic leukemia 8093; nilotinib; 3 day' vs 'pre-B acute lymphoblastic leukemia 8093; nilotinib; 0 day'cell type, compound, timeDrug tolerance development of mouse Bcr/Abl pre-B ALL cells on irradiated MEFs
Adjusted p-valueLog2-fold change
3.0007 × 10-3-1
Atg5'Plasmodium chabaudi infection' vs 'no infection' in 'vaccination'infect, treatmentProtective vaccination against blood-stage malaria of Plasmodium chabaudi: differential gene expression in the liver of Balb/c mice towards the end of crisis phase
Adjusted p-valueLog2-fold change
1.1244 × 10-2-1
Atg5'fetal definitive erythroid cell' vs 'primitive erythroid cell' in 'basophilic erythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.1905 × 10-21
Atg5'heat-shocked at 42 degreeC' vs 'grown at 33 degreeC' in 'HdhQ111 knock-in'genotype, growth conditionTranscription profiling by array of mouse wild type and Htt mutant striatal cells upon heat shock
Adjusted p-valueLog2-fold change
1.4039 × 10-2-1
Atg5'adult definitive erythroid cell' vs 'primitive erythroid cell' in 'proerythroblast'cell type, phenotypeTranscription profiling by array of differentiating primary primitive and definitive mouse red blood cells
Adjusted p-valueLog2-fold change
1.9805 × 10-2-1
Atg5'actinomycin D; 8 hour' vs 'none' in 'Cnot1 flox/flox'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
2.0776 × 10-2-1
Atg5'Tetrafluororethane; 50000 part per million; air' vs 'none; ; air'compound, treatmentTranscription profiling by array of Mus musculus liver tissue after exposure to various carcinogenic chemicals
Adjusted p-valueLog2-fold change
2.8608 × 10-21
Atg5'V6.5; embryonic stem cell’ vs 'wild type; endothelial'cell line, cell type, genotypeCD47 Inhibits Self-renewal and Reprogramming by Regulating c-Myc and Other Stem Cell Transcription Factors
Adjusted p-valueLog2-fold change
3.2917 × 10-21
Atg5'osteosarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Synonym
2010107M05Rik, Apg5l, 3110067M24Rik, Paddy
Ortholog
Gene ontology
InterPro
Ensembl gene
Ensembl transcript
Ensembl protein
Entrez
UniProt
MGI ID (Mouse)
MGI description
Gene biotype
Design element
5011128, 10344127, ILMN_1217612, 10338401, 94225_at, 5598983, 4479694, 5292021, A_52_P254981, 10338565, 5343189, 1418236_s_at, 10340552, 10343205, 4337315, 4579422, 5375266, 4602276, 4911508, 10339127, 10339889, 1415684_at, 10339247, 4755258, ILMN_2998139, ILMN_2998135, 5045515, 4492605, 4453559, 5402713, 10341676, 10341553, 4470957, 5550623, 10342288, 10342567, 10338984, A_55_P2015113, 10338268, 10362922, 10340657, 4521059, 4678555, 4741350, 10340175, 5515094, 10342257, 10340291, 4471870, 4799747, 1418235_at, 10343908, 17233061, 4350258, 10342184
Reactome pathway ID