ENSMUSG00000044378 (Slc15a5)

mus musculus

solute carrier family 15, member 5

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Mus musculus
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Showing 14 experiments:
Created with Highcharts 6.2.0arcuate nucleus of hypothalamusbrainbrown adipose tissuecentral neural epitheliumcerebellumcolondorsal control neural epitheliumdorsal raphe nucleushearthippocampal formationkidneylateral nasal prominencelateral prominence neural epitheliumliverlungmandibular archmaxillary archmedial nasal prominencemuscle tissueolfactory epitheliumolfactory pitskeletal muscle tissuespleentestisthymusvomeronasal organwhite adipose tissuezone of skin
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Vertebrates
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9 in 3 strains - DBA/2J
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9 in 3 strains - CD1
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9 in 3 strains - C57BL/6
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4 Bonthuis et al - CastEiJ
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Mammalian Kaessmann
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Fat and muscle
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3 Soumillon et al
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2
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14 - embryonic day 10.5
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4 Bonthuis et al - C57BL/6J
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4 Bonthuis et al - (C57BL/6J X …
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Proteomics
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Transcriptomics
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-4.7
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Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
4.1152 × 10-19-4.7
Slc15a5'Alb-Cre-ERT2 / Cnot1 flox/flox' vs 'Cnot1 flox/flox' in 'none'compound, genotype, timeRNA-seq of livers in control and Cnot1 tamoxifen-inducible liver-specific knockout mice
Adjusted p-valueLog2-fold change
1.6241 × 10-6-3.8
Slc15a5'hepatocyte-derived proliferative ducts (hepPDs)' vs 'hepatocyte'cell typeTranscription profiling by high throughput sequencing of hepatocyte-derived progenitors cells in a mouse model of oval cell activation
Adjusted p-valueLog2-fold change
1.7122 × 10-6-3.7
Slc15a5'conditional Kras and p53 mutation induced soft tissue sarcoma' vs 'normal'diseaseTranscription profiling by array of mouse soft tissue sarcoma samples induced by conditional mutations of Kras and p53 against healthy muscles from mice of the same genotype but no induced sarcoma
Adjusted p-valueLog2-fold change
1.8471 × 10-2-3.3
Slc15a5'clear cell sarcoma; Rosa26CreER' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.5216 × 10-7-2.8
Slc15a5'high fat diet' vs 'normal chow' in '28 week; ReverbαFlox2-6AdipoCre+'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
5.3904 × 10-7-2.8
Slc15a5'ko cyld-/-' vs 'wild type'genotypeTranscription profiling by array of mouse liver with Cyld inactivation
Adjusted p-valueLog2-fold change
2.5487 × 10-4-2.6
Slc15a5'Pax7 driven ablation of miR-1/133a' vs 'wild type'phenotypeMetabolic maturation during muscle stem cell differentiation is achieved by miR-1/133a-mediated inhibition of the Dlk-Dio3 mega gene cluster.
Adjusted p-valueLog2-fold change
3.1068 × 10-2-2.6
Slc15a5'synovial sarcoma' vs 'control'disease, genotypeMouse Model of Clear Cell Sarcoma
Adjusted p-valueLog2-fold change
1.8346 × 10-4-2.5
Slc15a5'hepatocyte-specific deletion of JAK2' vs 'wild type genotype' in '40 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
6.4251 × 10-4-2.5
Slc15a5'transgenic hepatic growth hormone and hepatocyte-specific deletion of JAK2' vs 'wild type genotype' in '40 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
2.2345 × 10-2-2.5
Slc15a5'high fat diet; 30 degree celsius' vs 'chow; 23 degree celsius' in 'brown adipose tissue'diet, organism part, temperatureRNA-seq of brown and white mouse adipose tissue at thermoneutrality and high-fat diet
Adjusted p-valueLog2-fold change
1.212 × 10-32.4
Slc15a5'adipose tissue specific Cnot1 knockout' vs 'wild type phenotype' in 'brown adipose tissue'organism part, phenotypeRNA-seq to identify the role of mRNA decay in mouse adipose tissues
Adjusted p-valueLog2-fold change
1.7611 × 10-3-2.3
Slc15a5'transgenic hepatic growth hormone' vs 'wild type genotype' in '40 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
1.4239 × 10-2-2.3
Slc15a5'24 month; Pgc-1 alpha knockout' vs '24 month; wild type'age, genotypeProgressive loss of PGC-1alpha expression in aging muscle potentiates glucose intolerance and systemic inflammation
Adjusted p-valueLog2-fold change
1.0883 × 10-5-2.2
Slc15a5'Pax7 driven Mef2a overexpression' vs 'wild type'phenotypeMetabolic maturation during muscle stem cell differentiation is achieved by miR-1/133a-mediated inhibition of the Dlk-Dio3 mega gene cluster.
Adjusted p-valueLog2-fold change
7.9094 × 10-52
Slc15a5'alpha-amanitin; maternal Ring1-Rnf+' vs 'none; maternal Ring1-Rnf+'compound, genotypePolycomb function during oogenesis is required for mouse early embryonic development (2-cell embryos)
Adjusted p-valueLog2-fold change
1.0402 × 10-4-2
Slc15a5'cardiotoxin; 40 microliter' vs 'none' in 'wild type' at '12 day'compound, genotype, timeTranscription profiling by array of mouse skeletal muscle expressing CnAa or CnAb1 under the control of the MLC promoter after treatment with cardiotoxin
Adjusted p-valueLog2-fold change
4.668 × 10-2-2
Slc15a5'liver-specific Cnot3 knockout' vs 'wild type'phenotypeRoles of mRNA decay in liver development
Adjusted p-valueLog2-fold change
4.8709 × 10-61.9
Slc15a5'Reverbα-/- global knockout' vs 'Reverbα wild type' in 'not applicable; 13 week'age, diet, genotypeTissue-autonomous regulation of adipose expansion by core clock protein REVERBα
Adjusted p-valueLog2-fold change
7.3079 × 10-4-1.9
Slc15a5'NEMO-TNFR1 double knockout' vs 'wild type'genotypeTNFR1 controls apoptosis and chronic liver disease in hepatocyte-specific IKKγ (Nemo) mice.
Adjusted p-valueLog2-fold change
5.0334 × 10-31.9
Slc15a5'Stat5a (Stat5abnull/Stat5b-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
1.0696 × 10-4-1.8
Slc15a5'Yin Yang 1 (YY1) knockout' vs 'wild type'genotypeExpression data from mouse skeletal muscle
Adjusted p-valueLog2-fold change
1.455 × 10-21.8
Slc15a5'Stat5b (Stat5abnull/Stat5a-)' vs 'wild type' at 'pregnancy'genotype, sampling time pointTranscription profiling by high throughput sequencing of mouse wild type and Stat5-mutant mammary tissues at parturition and early pregnancy
Adjusted p-valueLog2-fold change
4.1139 × 10-21.8
Slc15a5"98 to 119 week; reproductively old" vs "6 to 12 week; reproductively young"age, phenotypeRNAseq of whole ovarian follicles from young and old mice.
Adjusted p-valueLog2-fold change
1.9977 × 10-2-1.7
Slc15a5'transgenic hepatic growth hormone and hepatocyte-specific deletion of JAK2' vs 'wild type genotype' in '12 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
2.6917 × 10-2-1.7
Slc15a5'hepatocyte-specific deletion of JAK2' vs 'wild type genotype' in '12 week'age, genotypeHepatic Deletion of Janus Kinase 2 Counteracts Inflammation, Oxidative Stress and Liver Cancer Formation in Growth Hormone Transgenic Mice
Adjusted p-valueLog2-fold change
2.2569 × 10-31.6
Slc15a5'dihydrotestosterone; 45 microgram per day' vs 'vehicle; ' on 'Affymetrix MOE430A array' on 'Affymetrix GeneChip Mouse Expression Array MOE430A [MOE430A]'compoundTranscription profiling of mouse after gonadectomy and treatment with estradiol, dihydrotestosterone or vehicle to compare gene expression in gastrocnemius
Adjusted p-valueLog2-fold change
1.1919 × 10-3-1.5
Slc15a5'NEMO knockout' vs 'wild type'genotypeTNFR1 controls apoptosis and chronic liver disease in hepatocyte-specific IKKγ (Nemo) mice.
Adjusted p-valueLog2-fold change
4.5 × 10-2-1.4
Slc15a5'injected with sperm-derived RNA fragments from mice subjected to early life stress (MSUS)' vs 'injected with sperm-derived RNA fragments from control non-stressed mice'stimulusZygotic expression after parental early life stress
Adjusted p-valueLog2-fold change
3.6679 × 10-41.3
Slc15a5'730 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
6.1712 × 10-4-1.3
Slc15a5'Dicer knock out' vs 'wild type'genotypeTranscription profiling by array of mouse Dicer-deficient ooctyes
Adjusted p-valueLog2-fold change
6.0802 × 10-61.2
Slc15a5'60 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
9.5 × 10-4-1.2
Slc15a5'isocaloric high-fat diet' vs 'control diet'dietMouse adipose tissue under hypercaloric and isocaloric high-fat diet
Adjusted p-valueLog2-fold change
7.0317 × 10-3-1.2
Slc15a5'streptozotocin' vs 'mock'treatmentLiver adapts mitochondrial function to insulin-resistant and diabetic states in mice
Adjusted p-valueLog2-fold change
8.1861 × 10-3-1.2
Slc15a5'PGC-1 beta knock in' vs 'wild type'genotypeTranscription profiling by array of skeletal muscle from PGC-1 beta transgenic mice
Adjusted p-valueLog2-fold change
8.4956 × 10-51.1
Slc15a5'90 day' vs '1 day'ageTranscriptional profilling of female mice liver as a function of age
Adjusted p-valueLog2-fold change
1.3954 × 10-41.1
Slc15a5'Sik1 knockout; abdominal muscle' vs 'wild type genotype; abdominal muscle'genotype, organism part, sampling siteRNAseq of coding RNA in the liver, spleen, kidney, abdominal muscle and gonadal adipose tissue of knock out mice and wild type controls.
Adjusted p-valueLog2-fold change
4.077 × 10-2-1.1
Slc15a5'hepatocyte-specific Pten and Tgfbr2 knockout' vs 'wild type'genotypeHepatocyte-specific knockout of Pten and of Pten and Tgfbr2 in mice
Adjusted p-valueLog2-fold change
1.7612 × 10-3-1
Slc15a5'Het (Q175) knock-in' vs 'wild type' in 'white adipose tissue around gonad'genotype, organism partTranscriptome profiling in knock-in mouse models of Huntington's disease [AllelicSeries_6month_TissueSurvey_mRNA]