-8.9 | | Car10 | 'Cox6a2 knockout' vs 'wild type' | phenotype | RNA-seq of PV+ interneurons in WT and Cox6a2-/- mice to unravel the molecular signaling that contributes to the increase in oxidative stress and metabolic dysregulation following Cox6a2 knockout. |
-5.2 | | Car10 | 'extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
5.1 | | Car10 | 'induced neuronal cell' vs 'pluripotent embryonic stem cell' | phenotype | Transcription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells |
-4.8 | | Car10 | 'induced extraembryonic endoderm stem cell; grown in XEN cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-4.8 | | Car10 | 'induced extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
4.3 | | Car10 | 'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
3.9 | | Car10 | "98 to 119 week; reproductively old" vs "6 to 12 week; reproductively young" | age, phenotype | RNAseq of whole ovarian follicles from young and old mice. |
-3.9 | | Car10 | 'neural progenitor cell' vs 'niche cell' | cell type | Transcription profiling by high throughput sequencing of three populations of primary dentate gyrus cells |
3.8 | | Car10 | 'Insm1-expressing/Pdx1-high expressing endocrine progenitor cell' vs 'Insm1-expressing/Pdx1-low expressing endocrine progenitor cell' in 'embryonic day 15.5' | cell type, developmental stage | Transcriptional regulation of endocrine cell differentiation by Insm1 |
-3.8 | | Car10 | 'cortical epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1-Ly51+ td-tomato+t vs 'medullary epithelial cell; Lin- Dapi-EpCAM+ CD31-UEA1+Ly51- td-tomato-' | cell type, phenotype | Thymic T-cell progenitor development is supported by membrane bound Kit ligand provided by a combined vascular endothelial and epithelial niche. |
3.7 | | Car10 | 'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
3.2 | | Car10 | 'P60; insulin-expressing mature beta cells' vs 'E16.5; insulin-expressing nascent beta cells' | age, cell type | Transcriptional profiling of nascent and mature pancreatic beta cells |
3.1 | | Car10 | 'extracellular vesicle; non-stimulated culture medium' vs 'none' | sampling site, stimulus | Cellular and extracellular vesicle RNA sequence for E-cadherin-RFP EMT reporter system expressing mouse breast cancer cell line Py2T during EMT/MET |
-3 | | Car10 | 'extraembryonic endoderm stem cell; grown in ES cell medium' vs 'mouse embryonic fibroblast; control' | cell type, growth condition | OSKM induce extraembryonic endoderm stem (iXEN) cells in parallel to iPS cells |
-2.6 | | Car10 | 'subventicular zone of the lateral ventricle' vs 'cerebellum' | organism part | Expression data from adult Shh-responding astroglia cells in mice |
2.5 | | Car10 | 'postnatal day 60' vs 'postnatal day 1' in 'insulin-expressing immature beta cell' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
2.5 | | Car10 | '4-hydroxytamoxifen-mediated deletion of Prmt5' vs 'wild type' in 'mouse neural progenitor cell' | cell type, phenotype | Transcription profiling by high throughput sequencing of murine neural stem/progenitor cells lacking PRMT5 over control |
2.5 | | Car10 | 'neurosphere in differentiation medium; 12 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
2.5 | | Car10 | '10 day' vs '0 day' | age | Transcriptional profiling by array of mouse cerebellar cortex during postnatal development |
2.4 | | Car10 | 'etoposide; 2.5 micromolar' vs 'none' in 'wild type genotype' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
-2.4 | | Car10 | 'hippocampus' vs 'cerebellum' | organism part | Expression data from adult Shh-responding astroglia cells in mice |
2.4 | | Car10 | 'AZD7507; 100 milligram per kilogram' vs 'none' | compound | RNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069 |
2.2 | | Car10 | 'neurosphere in differentiation medium; 5 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
2.2 | | Car10 | 'transplanted secondary tumors' vs 'normal' in 'kidney' | clinical information, organism part | Premature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array] |
2.1 | | Car10 | 'calorie restricted diet' vs 'normal diet' at '15 month' | age, diet | Transcription profiling by array of cochleae from mice fed a calorie-restricted diet |
2.1 | | Car10 | 'neurogenin-3-expressing endocrine progenitor cell' vs 'neurogenin-3-lacking pancreatic progenitor cell' at 'embryonic day 15.5' | cell type, developmental stage | Transcription profiling by high throughput sequencing of murine beta cells at key stages of maturation |
-2.1 | | Car10 | 'adenoviral vector expressing human ACE2' vs 'empty adenoviral vector' | genotype | RNA-seq of SARS-CoV-2 infected lungs from mice sensitized for SARS-CoV-2 infection by Ad5-hACE2 transduction compared to non-sensitized mice |
2 | | Car10 | 'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'wild type genotype' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
1.9 | | Car10 | 'etoposide; 2.5 micromolar' vs 'none' in 'H2afj-∆7-KO' | compound, genotype | RNA-seq of H2afj-ko and isogenic WT C57/Bl6-N mouse embryonic fibroblasts in proliferation and after etoposide-induced senescence. |
1.9 | | Car10 | 'PDE10 inhibitor; PDE10A knockout; striatum' vs 'PDE10 inhibitor; wild type; striatum' | compound, genotype, organism part | Microarray profiling of WT or PDE10A KO mice treated with vehicle or a PDE10 inhibitor |
1.8 | | Car10 | 'alpha-amanitin; maternal Ring1-Rnf+' vs 'none; maternal Ring1-Rnf+' | compound, genotype | Polycomb function during oogenesis is required for mouse early embryonic development (2-cell embryos) |
-1.8 | | Car10 | 'XBP1s overexpression' vs 'wild type genotype' in '4μ8C; 15 micromolar' | compound, genotype | Overexpression of spliced XBP1 in in vitro Th2 cells, and comparison to 4u8c treatment |
1.8 | | Car10 | 'Insm1-expressing/Pdx1-high expressing endocrine progenitor cell' vs 'Insm1-expressing/Pdx1-low expressing endocrine progenitor cell' in 'embryonic day 18.5' | cell type, developmental stage | Transcriptional regulation of endocrine cell differentiation by Insm1 |
-1.7 | | Car10 | 'beta cell specific Pax6 knockout' vs 'wild type' | phenotype | RNA-Seq of pancreatic islets from beta cell-specific Pax6 knockout mice |
-1.6 | | Car10 | 'metaphase II oocyte' vs 'germinal vesicle oocyte' | cell type | Transcription profiling of mouse in vivo matured MII oocytes and fully in vivo grown germinal vesicle oocytes to identify gene transcripts linked to epigenetic reprogramming |
1.5 | | Car10 | 'neuron' vs 'differentiating progenitor' | cell type | Transcription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line |
1.5 | | Car10 | 'Crx knockout' vs 'control' at '6 zeitgeber' | genotype, time | Transcriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20 |
1.5 | | Car10 | 'neurosphere in differentiation medium; 1 day' vs 'neurosphere; 0 day' in 'Cstb knockout' | genotype, growth condition, time | Transcriptome analysis of neurospheres derived from Cstb-KO mouse embryo brains during differentiation |
1.5 | | Car10 | 'Insm1-expressing endocrine progenitor cell' vs 'Insm1-lacking endocrine progenitor cell' in 'embryonic day 15.5' | cell type, developmental stage | Transcriptional regulation of endocrine cell differentiation by Insm1 |
-1.4 | | Car10 | 'permanent neonatal diabetes mellitus' vs 'normal' | disease | Microarray comparing gene expression changes between control, normoglycaemic mice, and mice expressing the human neonatal diabetes mutation Kir6.2-V59M in pancreatic beta-cells left diabetic for 2 weeks |
-1.4 | | Car10 | 'Hnf4a-pKO;Hnf1aHET double mutant' vs 'wild type genotype' | genotype | Transcription profiling by array of pancreatic islets from pancreas-specific Hnf4alpha knockout, heterozygous Hnf1alpha, and double mutant mice |
-1.3 | | Car10 | 'glioblastoma multiforme' vs 'normal' | disease | Analysis of the expression profiles of glioma-associated microglia/macrophages and naive control cells in Mus musculus. |
-1.3 | | Car10 | 'dorsolateral nucleus motor neuron' vs 'lumbar motor neurons' | cell type | Comparison of gene expression in motor pools with differential vulnerability in ALS |
-1.3 | | Car10 | 'proliferating progenitor' vs 'differentiating progenitor' | cell type | Transcription profiling by high throughput sequencing of proliferating neural stem cells, differentiating neurogenic progenitors and newborn neurons using a dual-reporter mouse line |
-1.3 | | Car10 | 'co-cultured with hematopoietic stem cell for 9 days' vs 'non co-cultured for 9 days' in 'stromal cell; expressing AKT1' | cell type, growth condition, phenotype | Transcription profiling by high throughput sequencing of murine bone marrow endothelial cells and bone marrow stroma, in vitro and in vivo, with and without hematopoietic stem cells co-culture |
-1.2 | | Car10 | 'Chikungunya virus; late stage encephalitis' vs 'mock infection' | infect, time | Transcriptomic profiling of the brains of WNV and CHIKV infection-induced encephalitis in young mice after 2, 3 or 5 days post infection |
-1.2 | | Car10 | 'pancreas-specific Hnf4alpha knockout' vs 'wild type genotype' | genotype | Transcription profiling by array of pancreatic islets from pancreas-specific Hnf4alpha knockout, heterozygous Hnf1alpha, and double mutant mice |
1.2 | | Car10 | 'Crx knockout' vs 'control' at '20 zeitgeber' | genotype, time | Transcriptome in 129sv and Crx-/- pineal gland at ZT (Zeitgeber time) 6 and ZT20 |
1.1 | | Car10 | 'SOD1-G93A transgenic' vs 'wild type' at 'day 65' in 'B6/SJL' | genotype, sampling time point, strain | Transcription profiling by high throughput sequencing of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model |
-1.1 | | Car10 | '120 day; Sod1 G93A' vs '120 day; wild type genotype' | age, genotype | Transcription profiling of astrocytes from the symptomatic and late-stage time points of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis (ALS) |
1 | | Car10 | '7 day' vs '0 day' | age | Transcriptional profiling by array of mouse cerebellar cortex during postnatal development |
-1 | | Car10 | 'Hnf1a knock out' vs 'wild type' | genotype | Transcription profiling of pancreatic islets from Hnf1a-deficient and wild type mice |
