ENSMUSG00000070619 (Pramel31)

mus musculus

PRAME like 31

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Mus musculus
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Showing 16 experiments:
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9 in 3 strains - DBA/2J
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14 - embryonic day 10.5
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14 - embryonic day 9.5
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14 - embryonic day 8.5
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4 Bonthuis et al - CastEiJ
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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9 in 3 strains - CD1
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4 Bonthuis et al - C57BL/6J
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Mernberger et al 2019 - Organism Part
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9 in 3 strains - C57BL/6
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6
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9
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Gregg et al - CAST/EiJ
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Gregg et al - C57BL/6J
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4 Bonthuis et al - Idaho derived wild …
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Proteomics
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Transcriptomics
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
5.4265 × 10-583.6
Pramel31'induced neuronal cell' vs 'pluripotent embryonic stem cell'phenotypeTranscription profiling by high throughput sequencing of retinoic acid-differentiated neuronal cells compared to nondifferentiated pluripotent embryonic stem cells
Adjusted p-valueLog2-fold change
1.086 × 10-83.2
Pramel31'Drosha -/-' vs 'wild type genotype'genotypeRNA-seq of mouse ES cells with conditional Drosha knockout against wild type controls to identify pri-miRNAs
Adjusted p-valueLog2-fold change
1.2584 × 10-242.3
Pramel31'Zbtb2 -/-' vs 'wild type genotype' in 'EpiLC' at '2 day'genotype, growth condition, timeRNA-seq for wild-type and Zbtb2 knock-out clones of mESCs in 2iLIF, EpiLC and SerumLIF conditions.
Adjusted p-valueLog2-fold change
1.7724 × 10-172
Pramel31'Zbtb2 -/-' vs 'wild type genotype' in 'EpiLC' at '1 day'genotype, growth condition, timeRNA-seq for wild-type and Zbtb2 knock-out clones of mESCs in 2iLIF, EpiLC and SerumLIF conditions.
Adjusted p-valueLog2-fold change
1.9933 × 10-52
Pramel31'Mettl6 knockout clone D1' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
1.1518 × 10-391.8
Pramel31'Trim24 knockdown' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of mouse embryonic stem cells following Trim24 and/or p53 knockdown
Adjusted p-valueLog2-fold change
5.4477 × 10-51.8
Pramel31'Mettl6 knockout clone G6' vs 'wild type genotype'genotypeMETTL6 is a tRNA m3C methyltransferase that regulates translation and tumor cell proliferation
Adjusted p-valueLog2-fold change
9.123 × 10-4-1.8
Pramel31'PF-04691502–resistant cell; 1 micromolar; PF-04691502' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
1.679 × 10-2-1.6
Pramel31'129S1 allele at SNP rs50454566' vs 'wild type genotype'genotypeRNA-Seq of mouse embryonic stem cells derived from genetically diverse inbred mouse strains with varying alleles at Lifr gene
Adjusted p-valueLog2-fold change
2.98 × 10-81.5
Pramel31'Zbtb2 -/-' vs 'wild type genotype' in 'SerumLIF' at '2 day'genotype, growth condition, timeRNA-seq for wild-type and Zbtb2 knock-out clones of mESCs in 2iLIF, EpiLC and SerumLIF conditions.
Adjusted p-valueLog2-fold change
5.4649 × 10-3-1.5
Pramel31'NOD allele at SNP rs50454566' vs 'wild type genotype'genotypeRNA-Seq of mouse embryonic stem cells derived from genetically diverse inbred mouse strains with varying alleles at Lifr gene
Adjusted p-valueLog2-fold change
1.8503 × 10-2-1.5
Pramel31'PF-04691502–resistant cell; 1 micromolar; PF-04691502 removed for 48 hours' vs 'parental AKP cell; dimethyl sulfoxide'compound, phenotypeResistance to PI3K/mTOR inhibitor PF-04691502 in KRAS mutant colorectal cancer models reveals a sensitivity to combination with EGFR inhibition
Adjusted p-valueLog2-fold change
8.8611 × 10-101.4
Pramel31'Zbtb2 -/-' vs 'wild type genotype' in 'SerumLIF' at '1 day'genotype, growth condition, timeRNA-seq for wild-type and Zbtb2 knock-out clones of mESCs in 2iLIF, EpiLC and SerumLIF conditions.
Adjusted p-valueLog2-fold change
2.1813 × 10-51.3
Pramel31'Sall4 ZFC4mut' vs 'wild type genotype'genotypeRNA-Seq of Sall4 mutants in mouse embryonic stem cells
Adjusted p-valueLog2-fold change
3.7454 × 10-131.2
Pramel31'Trim24,Trp53 double knockdown' vs 'wild type'genotypeTranscription profiling by high throughput sequencing of mouse embryonic stem cells following Trim24 and/or p53 knockdown
Adjusted p-valueLog2-fold change
7.4108 × 10-81.2
Pramel31'Zbtb2 -/-' vs 'wild type genotype' in '2iLIF' at '0 day'genotype, growth condition, timeRNA-seq for wild-type and Zbtb2 knock-out clones of mESCs in 2iLIF, EpiLC and SerumLIF conditions.
Adjusted p-valueLog2-fold change
9.5001 × 10-31
Pramel31'PH3 homozygous knockout' vs 'wild type phenotype'phenotypePHF3 binds RNA polymerase II via the SPOC domain and regulates transcription of neuronal genes - Mouse Embryonic Stem Cell RNAseq
Adjusted p-valueLog2-fold change
3.0744 × 10-2-1
Pramel31'3 day' vs '0 day'ageTime course analysis of the cardiac transcriptome in the neonatal period
Adjusted p-valueLog2-fold change
3.6579 × 10-2-1
Pramel31'Setd5 homozygous (null) knockout' vs 'Setd5 heterozygous knockout'genotypeTranscriptional profiling of Setd5 heterozygous and knockout mouse embryonic stem cells