ENSMUSG00000078505 (Aadacl4fm4)

mus musculus

AADACL4 family member 4

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Mus musculus
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Showing 28 experiments:
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Created with Highcharts 6.2.0adrenal glandbronchuscorpora quadrigeminaepidermal ectodermheartlateral prominence neural epitheliummedial nasal prominenceolfactory bulbpreoptic areastomachtonguevomeronasal organaxillary lymph nodecerebellumdiencephaloneyeball of camera-type eyeintestinemammary glandmuscle (biceps femoris)ovarysmall intestinesubventricular zoneuterus
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49 FANTOM5 project - adult
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9 in 3 strains - CD1
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9 in 3 strains - DBA/2J
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9
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Mernberger et al 2019 - Organism Part
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9 in 3 strains - C57BL/6
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49 FANTOM5 project - neonate
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4
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2
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14 - embryonic day 10.5
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Gregg et al - CAST/EiJ
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4 Bonthuis et al - CastEiJ
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4 Bonthuis et al - (CastEiJ X …
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4 Bonthuis et al - (C57BL/6J X …
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Vertebrates
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Mammalian Kaessmann
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6
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49 FANTOM5 project - pregnant adult day …
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49 FANTOM5 project - lactating adult …
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49 FANTOM5 project - juvenile
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49 FANTOM5 project - embryonic day 18
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49 FANTOM5 project - embryonic day 17
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49 FANTOM5 project - embryonic day 16
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14 - embryonic day 9.5
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Gregg et al - C57BL/6J
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Gregg et al - (CAST/EiJ X C57BL/6J)F1
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Gregg et al - (C57BL/6J X CAST/EiJ)F1
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4 Bonthuis et al - C57BL/6J
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Proteomics
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Transcriptomics
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Regulation
-1.3
-6.8
1.2
1.8
Display log2-fold change
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Log2-fold changeSpeciesGene nameComparisonExperimental variablesExperiment name
Adjusted p-valueLog2-fold change
7.8408 × 10-22-6.8
Aadacl4fm4'tamoxifen induction at 2 months, wait 1 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
7.0985 × 10-25-6.2
Aadacl4fm4'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'luminal cell of prostate epithelium; Nkx3.1-CreERT2 targeted allele'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
5.1944 × 10-25-5.3
Aadacl4fm4'tamoxifen induction at 2 months, wait 6 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
2.2249 × 10-24-5
Aadacl4fm4'tamoxifen induction at 2 months, wait 3 months' vs 'no tamoxifen induction' in 'basal cell of prostate epithelium; CK5-CreERT2 transgenic line'cell type, genotype, growth conditionTranscription profiling by high throughput sequencing of PIN/tumor lesions from basal or luminal origins at time points at which mice displayed similar histopathological phenotypes
Adjusted p-valueLog2-fold change
5.9206 × 10-61.8
Aadacl4fm4'K14-Cre-ERT2; none; UVB irradiation; 7 day' vs 'K14-Cre-ERT2; none; none'genotype, irradiate, timeAblation of casein kinase 1 in keratinocytes induces p53-dependent hyperpigmentation of the skin
Adjusted p-valueLog2-fold change
4.9914 × 10-5-1.3
Aadacl4fm4'K14-Cre-ERT2 / CK1α fl/fl / p53 fl/fl; 4-hydroxytamoxifen; none; 7 day' vs 'K14-Cre-ERT2; none; none'genotype, irradiate, timeAblation of casein kinase 1 in keratinocytes induces p53-dependent hyperpigmentation of the skin
Adjusted p-valueLog2-fold change
2.5956 × 10-31.2
Aadacl4fm4'Fam208a homozygous mutant' vs 'wild type'block, genotypeThe epigenetic modifier Fam208a is required to maintain epiblast cell potency